Allogeneic1
- In addition to complications seen from exposure to chemotherapy and radiation, patients undergoing allogeneic transplantation can experience unique late effects secondary to graft versus host disease (GVHD) and autoimmunity. (medscape.com)
Stem cells5
- Bone marrow contains stem cells, which are immature cells that become blood cells. (medlineplus.gov)
- Bone marrow donation can be done either by collecting a donor's bone marrow surgically, or by removing stem cells from a donor's blood. (medlineplus.gov)
- First, the donor is given 5 days of shots to help stem cells move from the bone marrow into the blood. (medlineplus.gov)
- For example, because hematopoietic stem cells can reconstitute the entire blood system, bone marrow transplantation has long been used in the clinic to treat various diseases. (articlecity.com)
- Similarly, the transplantation of other tissue-specific stem cells, such as stem cells isolated from epithelial and neural tissues, can treat mouse disease models and human patients in which epithelial and neural cells are damaged. (articlecity.com)
Myeloma3
- Myeloma cells destroy bone , which releases calcium, a condition called hypercalcemia. (webmd.com)
- Myeloma cells produce excess abnormal proteins, called paraproteins, in the bone marrow that can cause your blood to become so thick that it flows sluggishly in your body, a condition called hyperviscosity. (webmd.com)
- People with life-threatening cancers, such as leukemia , lymphoma , and myeloma can be treated with a bone marrow transplant or, sometimes, a stem cell transplant. (medlineplus.gov)
Transplant5
- In a study from the United States, long-term survivors of pediatric bone marrow transplantation followed in the Bone Marrow Transplant Survivors Study were compared with survivors of childhood cancer treated without bone marrow transplant from the Childhood Cancer Survivor Study. (medscape.com)
- Autologous bone marrow transplant is when people donate their own bone marrow. (medlineplus.gov)
- Allogenic bone marrow transplant is when another person donates bone marrow. (medlineplus.gov)
- But only about 30% of people who need a bone marrow transplant can find a matching donor in their own family. (medlineplus.gov)
- Doctors can then use the registry to find a matching donor for a person who needs a bone marrow transplant. (medlineplus.gov)
Donor4
- For this type of treatment, bone marrow is collected from a donor. (medlineplus.gov)
- Bone marrow transplants work best if the HLAs from the donor and the patient are a close match. (medlineplus.gov)
- Then, a counselor meets with the donor to discuss the bone marrow donation process. (medlineplus.gov)
- After a bone marrow harvest, the donor stays in the hospital until they're fully awake and can eat and drink. (medlineplus.gov)
Registry1
- The 70% of people who do not have a relative who is a good match may be able to find one through a bone marrow registry. (medlineplus.gov)
Cells1
- This bone marrow film at 400X magnification demonstrates a complete absence of hemopoietic cells. (medscape.com)
Transplants work1
- Bone marrow transplants work best if the HLAs from the donor and the patient are a close match. (medlineplus.gov)
Lymphoma3
- Stem cell and bone marrow transplants are sometimes used to treat types of cancer including leukaemia, lymphoma and myeloma. (macmillan.org.uk)
- Is bone marrow transplantation a cure for lymphoma and other blood cancers? (yashodahospitals.com)
- Lymphoma is a cancer of the lymphatic system, which comprises of the structures like the lymph nodes, spleen, thymus, bone marrow and vessels that carry the lymph fluid throughout the body. (yashodahospitals.com)
HSCT2
- Likewise, many children are now surviving hematopoietic stem-cell transplantation (HSCT) (see related histology slide below) and require structured long-term follow-up care. (medscape.com)
- This condition is fatal if those affected do not receive treatment through hematopoietic stem cell transplantation (HSCT). (info4pi.org)
Rescue2
- For example, while HSCs can support lifelong hematopoiesis after bone marrow transplantation (BMT), they have limited capacity to rescue the host from lethal conditioning 5 . (elifesciences.org)
- Therefore, BMT is also called as a bone marrow rescue. (yashodahospitals.com)
Blood7
- The bone marrow normally makes millions of new blood cells every day to replace blood cells as they are needed. (macmillan.org.uk)
- The European Society for Blood and Bone Marrow Transplantation: Hematopoietic stem cell transplantation and cellular therapies. (macmillan.org.uk)
- Thirdly, the CRA assesses HSC activity based on overall hematopoietic chimerism, which might reflect poorly on the actual HSC activity given the vastly different turnover rates of different blood cells lineages 13 . (elifesciences.org)
- Cancer involves the bone marrow, blood cells, and the lymphatic system. (yashodahospitals.com)
- The bone marrow helps regulate clotting, build bone and cartilage, blood cells regulate the flow of oxygen and carbon dioxide and the lymphatic system carries lymphatic fluid that is responsible for fighting infections, in presence of white blood cells. (yashodahospitals.com)
- Occurs in the blood and bone marrow. (yashodahospitals.com)
- The cancer cells surround the bone marrow and prevent it from producing normal cells, such as the red blood cells, white blood cells, and platelets. (yashodahospitals.com)
Replace1
- Your body will replace the donated bone marrow in about 4 to 6 weeks. (medlineplus.gov)
Back2
- The bone marrow is removed from the back of your pelvic bones. (medlineplus.gov)
- Once injected, bone marrow cells find their way back into bone marrow. (yashodahospitals.com)
Donate2
- Sometimes, people can donate their own bone marrow for future use. (medlineplus.gov)
- It registers people who would be willing to donate bone marrow and stores their information in a database. (medlineplus.gov)
Collection1
- FACT-JACIE International Standards for Hematopoietic Cellular Therapy - product collection, processing and administration. (macmillan.org.uk)
Disease1
- Bone marrow is part of our immune system, which protects us from infection and disease. (macmillan.org.uk)