• The physicochemical properties of Ti implant surfaces are fundamental to the success of osseointegration. (bvsalud.org)
  • To improve the biological responses for obtaining rapid osseointegration, the surfaces have been modified by a wide range of process involving mechanical, chemical, and physical surface treatment methods, such as: the Ti plasma spray treatment, Ti oxide blasting, laser deposition of Ti carbide, and acid conditioning 4 . (bvsalud.org)
  • Conclusions: The surface modified by acid conditioning followed the addition of fluoride ions provides superior osseointegration process, even in the later periods of bone regeneration. (unimi.it)
  • Seeding of bone implants with mesenchymal stem cells (MSCs) may promote osseointegration and bone regeneration. (nih.gov)
  • This preliminary study revealed that treatment with triple acid etching can create a promising and efficient surface for the process of osseointegration. (hindawi.com)
  • A predictable way to achieve long-term clinical success with dental implants is to ensure the intimate contact between the living bone and the implant, known as osseointegration [ 1 , 2 ]. (hindawi.com)
  • Studies have shown that, compared to a smooth surface, rough topography enhances the osseointegration [ 5 , 6 ]. (hindawi.com)
  • It was proposed that this surface may make the treatment more efficient and accelerate osseointegration because the surface topography influences bone integration on a micrometer level [ 9 ]. (hindawi.com)
  • Conclusion: A CaPO4 coating on an anodized surface may induce rapid osseointegration at the bone-implant interface and more bone formation near the implant surface. (snu.ac.kr)
  • To evaluate the osseointegration of implants with hydrophobic (HFB) and hydrophilic (HFL) surfaces in a murine model of high- dose bisphosphonates (BPs). (bvsalud.org)
  • Both surfaces enable osseointegration in rats under BP therapy . (bvsalud.org)
  • CLINICAL RELEVANCE The study demonstrates that hydrophobic (HFB) and hydrophilic (HFL) implant surfaces can promote osseointegration in rats undergoing bisphosphonate therapy . (bvsalud.org)
  • Purpose: The objectives of this study were to evaluate bioactivity of a titanium membrane with anodization, cyclic precalcification, and heat (APH) treatment (APHTM), and to compare APHTM and nontreated titanium membrane (NTTM) in guided bone regeneration using histologic analysis and microcomputed tomography (micro-CT). (quintpub.com)
  • Conclusion: The results suggest that APH treatment on titanium membrane promotes intimate bone formation toward the membrane, thus increasing structural durability for bone regeneration. (quintpub.com)
  • Accordingly, the association of Ti implants with bone tissue culture may contribute to bone tissue regeneration 7 . (bvsalud.org)
  • Aim: Evaluate the late bone regeneration around implants with machined (MS) and acid modified surfaces followed by the deposition of fluoride ions (AFS) in the tibiae of rabbits. (unimi.it)
  • Bone regeneration around implants with modified surface by acid conditioning with the fluoride ions deposition / A.S. De Souza, L.T. Colombo, H. Hadad, A.F.P. Santos, R. Capalbo-Silva, P.P. Poli, C.N. Elias, E. Vedovatto, F.A. Souza, P.S.P. Carvalho. (unimi.it)
  • Porous PEEK's porous surface technology introduces a porous architecture designed to promote bone in-growth 2 while maintaining the biomechanical and imaging properties of PEEK. (nuvasive.com)
  • This biomechanical study was designed to determine the effect of surgical washers used with olive wires on surface kinetics of the cortical bone. (aott.org.tr)
  • The dependent variables assessed were the removal torque (biomechanical analysis ), the bone volume around the implants (%BV/TV) (microtomographic analysis ), the bone -implant contact (%BIC), the bone between the threads (%BBT) (histomorphometric analysis ), and the expression of bone metabolism markers ( immunohistochemistry analysis ). (bvsalud.org)
  • The HFL surfaces exhibited improved biomechanical performance, higher bone -implant contact, and increased bone volume, suggesting their potential clinical relevance for implant success in individuals on bisphosphonate treatment . (bvsalud.org)
  • Background Regenerex is a novel porous titanium construct with a three-dimensional porous structure and biomechanical characteristics close to that of normal trabecular bone. (lu.se)
  • Learn how surface topography impacts bone fusion in ceramic bone graft substitutes and Porous PEEK spinal implants. (nuvasive.com)
  • Advanced surface technologies in ceramic bone graft substitutes and spinal implants have demonstrated the ability to better support bone healing in spinal fusions, which can lead to improved outcomes for patients. (nuvasive.com)
  • Anton Paar has developed specialized solutions for the surface analysis of biomaterials such as prostheses, implants, tissues, biopolymers and biofilms, teeth, various ophthalmic applications, and for medical devices such as stents, pills, and membranes. (anton-paar.com)
  • Biocompatible materials include a wide range of applications: from contact lenses and their storage solutions to real and artificial tissue, bone, and cartilage to implants, prostheses, and medical devices such as stents. (anton-paar.com)
  • Much of the industry uses this process for the finishing of implants, making it possible to standardize the topography, reduce discrepancies between peaks and valleys on the surface, remove encrusted surface particles, produce microtexturing on a previously treated surface, and eliminate the grooves resulting from the machining process [ 3 , 7 ]. (hindawi.com)
  • Indeed, in a study originally aimed to show that the bonding phenomenon is chemical in nature, surface topography changes in the micrometer range were observed in hydroxyapatite ceramic implants, suggesting that micromechanical interlocking contributed to the bonding mechanism [8]. (toysis.pics)
  • The %BIC of the CG-HFL surfaces was slightly higher than that of the CG-HFB implants. (bvsalud.org)
  • It articulates with (1) the parietal bones posteriorly at the coronal suture, (2) the nasal bones and the frontal process of the maxilla anteriorly and medially, (3) the frontal process of the zygoma at the frontozygomatic suture laterally, and (4) within the temporal fossa, with the greater wing of the sphenoid. (medscape.com)
  • We attempt to decipher the effects of submicron topography and microtopography on bone union phenomena and endosseous interface stability. (toysis.pics)
  • What emerges from an analysis of our results is a new means by which biologically relevant criteria can be used to assess the importance of implant surface Topography in different scale ranges. (toysis.pics)
  • However, contact osteogenesis can result in bone attachment to the implant surface if the implant has a surface topography with submicron physical undercuts [3]. (toysis.pics)
  • Furthermore, Howship's lacunae form themselves on a bone surface with an even higher order topography, as can be seen from the strut-like morphology of the bony trabeculae in cancellous bone. (toysis.pics)
  • This post-the fifth installment in the series-will discuss how best to promote musculoskeletal health and reduce the incidence of musculoskeletal disorders (MSDs) among surface stone, sand, and gravel mine workers. (cdc.gov)
  • Surface mine workers often develop musculoskeletal injuries in the back, fingers, knees, and shoulders 1 . (cdc.gov)
  • Handling materials during loading and unloading or machine maintenance and repair is a frequent cause of musculoskeletal disorders among surface mine workers in minerals processing plants 4 . (cdc.gov)
  • Bones are part of the musculoskeletal system, which also includes muscles and the tissues that connect them (ligaments, tendons, and other connective tissue, called soft tissues). (msdmanuals.com)
  • When measuring the surface properties of biomaterials, researchers and also manufacturers face special challenges. (anton-paar.com)
  • Typical studies on biomaterials include measuring hardness and structural properties, characterization of surface charge, surface interaction, hydrophobic/hydrophilic properties, and many more. (anton-paar.com)
  • Download the SurPASS 3 biomaterials folder to see how zeta potential analysis combines the determination of adsorption kinetics with the characteristics of the adsorbed surface layer. (anton-paar.com)
  • A sandblasted/acid-etched surface and an anodized surface were used as positive controls, and a CaPO4-coated and anodized (CPA) surface was investigated as the experimental group. (snu.ac.kr)
  • The micro-CT analysis revealed significantly lower bone volume but higher bone mineral density in the APHTM samples than in the NTTM samples (P (quintpub.com)
  • However, implant material surfaces, such as titanium or bovine bone mineral, fail to support rapid and efficient attachment of MSCs, especially under serum-free conditions that may be desirable when human applications or tightly controlled experiments are envisioned. (nih.gov)
  • Programmes should also identify those at risk for fractures, on the basis of age, gender, bone mineral density, history of fracture, and lifetime use of agents such as alcohol, tobacco and corticosteroids, and incorporate strategies aimed at such people for preventing falls or lessening their impact. (who.int)
  • The cell surface glycoprotein CD24 exhibits the most prominent differential expression during osteogenic versus adipogenic differentiation of human BMSCs. (elsevierpure.com)
  • In undifferentiated human BMSCs, CD24 cell surface expression is variable among donors (range: 2%-10%) and increased by two to fourfold upon osteogenic differentiation. (elsevierpure.com)
  • Subsequent differentiation allows for rear- analysis of a set of mouse B lineage cell lines rep- rangements of the Ig light-chain (IgL) genes that replace the resenting defined stages of B cell development us- surrogate light-chain genes on the surface of the B cell [8]. (lu.se)
  • Hence, expression of the cell surface glycoprotein CD24 identifies a subpopulation of human BMSCs with reduced capacity for proliferation and extracellular matrix mineralization. (elsevierpure.com)
  • Assessing bone formation on hydrophilic and hydrophobic implant surfaces in a murine model treated with bisphosphonates. (bvsalud.org)
  • therapy also increased the %BBT at both implant surfaces. (bvsalud.org)
  • The bones of the forehead form the scaffold on which the soft tissues are draped. (medscape.com)
  • Inspired by elastography and Doppler imaging methods, this technique takes advantage of the difference between the mechanical and acoustic properties of bones and those of soft tissues to make the bone surface more easily distinguishable in US images. (houstonmethodist.org)
  • Bone surface concentrations were significantly higher than that of the control group at 4 h and thereafter. (elsevierpure.com)
  • The results of these preliminary experiments suggest that the use of the proposed technique has the potential to significantly enhance the detectability of bone surfaces in noisy ultrasound images. (houstonmethodist.org)
  • Here we demonstrate that a branched poly[Lys(Ser(i)-DL-Ala(m))] polymer functionalized with cyclic arginyl-glycyl-aspartate, when immobilized by simple adsorption to tissue culture plastic, surgical titanium alloy (Ti6Al4V), or Bio-Oss(®) bovine bone substitute, significantly accelerates serum-free adhesion and enhances seeding efficiency of human adipose tissue-derived MSCs. (nih.gov)
  • Therefore, the present study aimed to evaluate the adhesion capacity of mouse bone marrow MSCs to smooth and plasmanitrided Ti surfaces in the cathodic cage configuration. (bvsalud.org)
  • In summary, the presented novel polypeptide conjugate can be conveniently used for coating various surfaces, and may find applications whenever quick and efficient seeding of MSCs is required to various scaffolds in the absence of serum. (nih.gov)
  • AttraX initiates new bone formation on its own without added cells or growth factors, 1 unlike traditional synthetic bone graft substitutes. (nuvasive.com)
  • inproceedings{CAOS2019:interleaved_partial_active_shape, author = {Benjamin Hohlmann and Klaus Radermacher}, title = {The interleaved partial active shape model (IPASM) search algorithm -- towards 3D ultrasound-based bone surface reconstruction}, booktitle = {CAOS 2019. (easychair.org)
  • Here we show that bone marrow endosteal SSCs are defined by fibroblast growth factor receptor 3 ( Fgfr3 ) and osteoblast-chondrocyte transitional (OCT) identities with some characteristics of bone osteoblasts and chondrocytes. (nature.com)
  • Surface characteristics were analyzed with field emission scanning electron microscopy, energy dispersive spectroscopy, and confocal laser scanning microscopy. (snu.ac.kr)
  • After removing the damaged knee cartilage and bone, the surgeon attaches the artificial parts to your bones. (medlineplus.gov)
  • It is well-described that leptin receptor (LepR) + perivascular stromal cells provide a major source of bone-forming osteoblasts in adult and aged bone marrow. (nature.com)
  • These Fgfr3 + stem/stromal cells with OCT identities are abundant in the young bone marrow and depleted in the old bone marrow, denoting their transitional nature. (nature.com)
  • Overall, our findings indicate that Fgfr3 + endosteal stem/stromal cells with OCT identities dictate active and aggressive osteogenesis, identifying these cells as an important regulator of long-term bone homeostasis. (nature.com)
  • Where necessary, we subjected the bone-implant interface to a mechanical fracture test. (toysis.pics)
  • A fracture is a crack or break in a bone. (msdmanuals.com)
  • Treatment depends on the type and severity of the fracture and may include pain relievers, PRICE (protection, rest, ice, compression, and elevation), maneuvers or procedures to move the fractured bone fragments back into their normal position (reduction), immobilization of the injured part (for example, with a cast or splint), and sometimes surgery. (msdmanuals.com)
  • Fluorochrome bone markers were injected in three rats in each group at 3 (alizarin red) and 5 weeks (calcein green), followed by histologic examination at 7 weeks. (quintpub.com)
  • Thus, the proximal portion of nails and bone surface are suitable biomarkers for acute fluoride exposure in rats. (elsevierpure.com)
  • This formation helps deposition and adhesion of the extracellular matrix on the bone-implant interface. (bvsalud.org)
  • The c-surface exposure was realized by crystal orientation in HAP-based catalyst film, which was created by an electrochemical deposition of HAP seeds on a titanium substrate, followed by hydrothermal crystallization and peeling off of the crystalline films from the substrate. (osti.gov)
  • At 2 and 4 weeks, APHTM samples showed an intimate bone formation onto the membrane, whereas NTTM samples demonstrated interposition of connective tissue between the membrane and newly formed bone. (quintpub.com)
  • Ti is a very stable metal, although slight oxide formation occurs on its surface. (bvsalud.org)
  • The distinct catalytic activity between these two crystalline surfaces is attributed to the preferential formation of oxide ions and vacancies on c-surfaces. (osti.gov)
  • Density functional theory calculations confirmed the close relationship between different catalytic activities in c-surface of oriented and a-surface of unoriented HAP through the tendency of vacancy formation. (osti.gov)
  • More specifically, recent studies have focused on strengthening this interface and accelerating bone formation and healing time, resulting in a rapid recovery of function [ 3 , 4 ], greater satisfaction of the dentist with the results, and improved quality of life for the patient. (hindawi.com)
  • The bone marrow contains various populations of skeletal stem cells (SSCs) in the stromal compartment, which are important regulators of bone formation. (nature.com)
  • However, the identity of SSCs in young bone marrow and how they coordinate active bone formation remains unclear. (nature.com)
  • However, the identity of bone marrow SSCs during the transition, and how they contribute to active bone formation occurring in young stages remains unclear. (nature.com)
  • EverClean Surface - Using the antimicrobial properties of silver (the precious metal), EverClean Surfaces inhibit the growth of bacteria, mold, and mildew. (faucet.com)
  • Analyzing mechanical properties on and below the treated enamel surface is of great interest for teeth treatments, e.g. in caries (cavities) prevention or for the minimally invasive treatment of early caries lesions. (anton-paar.com)
  • Ionic nitriding is a surface treatment method which exhibits excellent mechanical properties, chemical stability, and biocompatibility when applied to Ti. (bvsalud.org)
  • The impact of different percentage of cerium oxide on surface mechanical and tribological behaviour of the coating has been investigated. (inderscience.com)
  • [ 5 ] BMPs are members of the transforming growth factor-beta superfamily and play a role in the development of bone and other tissues. (medscape.com)
  • Overview of Sprains and Other Soft-Tissue Injuries Sprains are tears in ligaments (tissues that connect one bone to another). (msdmanuals.com)
  • The objective of this technique is to facilitate US-based bone segmentation methods and improve the accuracy of their outcomes. (houstonmethodist.org)
  • However, the clinical features of ameloblastoma, including its growth rate and patterns of invasion, are quite different from those of bone metastasis of cancer cells, suggesting that different underlying mechanisms are involved. (elsevierpure.com)
  • However, image quality of US imaging methods in bone applications is limited by speckle, attenuation, shadow, multiple reflections and other imaging artifacts. (houstonmethodist.org)
  • To reduce the risk of analyzing cell line- pathway can be divided into distinct stages based on the specific features, we used several representative cell lines for recombination status of the Ig genes and on the expression each of four major stages in B cell development: pro-B, pre-B, pattern of surface markers and the presence of intracellular proteins [1- 6]. (lu.se)
  • In this study, we report a novel population of SSCs with osteoblast-chondrocyte transitional (OCT) identities in the bone marrow endosteal space, which highly expresses Fgfr3 and contributes to both normal and aberrant osteogenesis. (nature.com)
  • Bony union means the interlocking of the cement matrix of the bone with the properties of the underlying implant surface. (toysis.pics)
  • It is believed that it expands in the jaw bone through peritumoral activation of osteoclasts by receptor activator of nuclear factor kappa-B ligand (RANKL) released from the ameloblastoma, as in bone metastases of cancer cells. (elsevierpure.com)
  • This sequence mimics the events that occur at sites of natural bone remodeling where the surface left by resorption of active osteoclasts presents a nanotopographically complex surface with undercuts [3], [4]. (toysis.pics)
  • In fact, it is salutary to emphasize that in natural bone remodeling, the cementum matrix invades the underlying resorbed bone surface to a depth of about one micron, which corresponds to the depth of penetration of the fibrous rim of the ruffled membrane of osteoclasts in the resorbed matrix. (toysis.pics)
  • However, using the natural bone interface as a model, it is also evident that osteoclasts produce Howship lacunae, which are depressions excavated in the bone surface ranging in size from microns to hundreds of microns. (toysis.pics)
  • We have also shown that topographically complex surfaces accelerate osteoconduction [5]. (toysis.pics)
  • Aim: To evaluate the adhesion of mouse bone marrow mesenchymal cells (MBMMC) on different titanium surfaces. (bvsalud.org)
  • The aim of this study was to evaluate the use of nails and the periosteal surface of bone as indicators of acute exposure to fluoride. (elsevierpure.com)
  • Purpose: The aim of this study was to evaluate the effectiveness of a calcium phosphate (CaPO4)-coated and anodized titanium surface in vitro and in vivo. (snu.ac.kr)
  • Ligaments (which attach bone to bone) can be torn (sprained). (msdmanuals.com)
  • Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue leading to increased susceptibility to fractures, most commonly of the hip, spine and wrist. (who.int)
  • Getting PEEK to stick to bone: the development of porous PEEK for interbody fusion devices. (nuvasive.com)
  • Radial Head Subluxation (Nursemaid's Elbow) Elbow dislocations occur when the lower end of the upper arm bone (humerus) loses contact with the tops (heads) of the forearm bones (radius and ulna). (msdmanuals.com)
  • Scientists were able to use the nanotopographical patterns on the biomedical plastic to manipulate human embryonic stem cells towards bone cells. (freedomsphoenix.com)
  • These properties determine the adhesion and behavior of cells in contact with the surface. (bvsalud.org)
  • Furthermore, vacuolar-type H+-ATPase (V-ATPase) and H+/Cl- exchange transporter 7 (CLC-7) were detected on the surface of AM-1 cells by plasma membrane biotinylation and immunofluorescence analysis. (elsevierpure.com)
  • The term "transitional" emphasizes the unique feature of these cells that are particularly abundant in the young bone marrow. (nature.com)
  • B lymphocyte development is a highly ordered process pro- expression analysis without the use of intermediate amplifica- ceeding from the progenitor cells in the bone marrow (BM) to tion steps. (lu.se)
  • FESEM images showed surface irregularities and micro-voids in the coating that does not have cerium oxide. (inderscience.com)
  • For example, fractures can range from a small, easily missed crack in a foot bone to a massive, life-threatening break in the pelvis. (msdmanuals.com)
  • This cavity is divided into two separate cavities by the septum and kept patent by a bone and cartilaginous framework. (nih.gov)
  • Additional risk factors, such as urbanization, with the consequent increase in harder surfaces, will also result in greater numbers of fractures. (who.int)
  • Most fractures result from force applied to a bone. (msdmanuals.com)
  • Gliding refers to the movement where one flat bone surface slides or slips over another similar surface. (proprofs.com)
  • Mining Publication: Simple Solutions for Surface Mine Workers This booklet provides examples of solutions and task design ideas you can use to reduce risks for MSDs and slips, trips, and falls. (cdc.gov)
  • Conclusions: It was demonstrated that titanium surface treatment with ionic nitriding in a cathodic cage is biocompatible since it preserved the integrity of the cultivated MBMMC for a period of 24 h, allowing their adhesion. (bvsalud.org)
  • Methods: Grade II titanium discs (ASTM F86) received two different surface treatments: polished (S1) and cathodic cage plasma nitriding (S2). (bvsalud.org)
  • they will need to train health-care workers, provide better access to bone densitometry (or other reliable methods of diagnosis), find ways of manufacturing or importing treatments decided upon, and create or adopt guidelines for treatment. (who.int)
  • This movement is commonly observed in joints like the elbow or knee, where the angle between the bones decreases as they come closer together. (proprofs.com)