Bone substitute. Medical search. Frequent questions

In modern medicine, damaged and missing bones are replaced with bone from either patient or donor or using artificial materials containing calcium, such as Plaster of Paris, and more recently, phosphate compounds like hydroxyapatite and calcium phosphate. (medindia.net)
An injectable ceramic bone substitute, with hydroxyapatite in a calcium sulphate matrix, containing 66 mg of vancomycin per millilitre, was inserted to augment the fixation. (boneandjoint.org.uk)
The exceptional properties of FlexiOss® mentioned above result from its unique composition (hydrogel-like carbohydrate polymer and highly microporous hydroxyapatite ceramics) which does not appear in other bone-substituting biomaterials, neither commercial nor experimental ones. (flexioss.pl)
Biphasic formulations associating the very bioactive β-Tricalcium Phosphate and the stable Hydroxyapatite that allows resorption at the right pace which leads in the creation of a new strong and qualitative bone. (primedentalsupply.com)
This study aimed to improve the performance and mode of administration of a glass -reinforced hydroxyapatite synthetic bone substitute , Bonelike by Biosckin® (BL®), by association with a dextrin -based hydrogel , DEXGEL, to achieve an injectable and moldable device named DEXGEL Bone . (bvsalud.org)
Ceramics: Synthetic ceramics, such as calcium phosphate-based materials (hydroxyapatite and tricalcium phosphate), closely resemble the mineral component of natural bone. (credenceturbine.com)
Incorporation of hydroxyapatite (HA) in a collagen scaffold dramatically improves bone morphogenic protein (BMP) sequestration via biophysical interactions with BMP, thereby providing more controlled BMP release compared with pristine collagen. (lu.se)

The interconnected and open porous structure of the silicate-substituted calcium phosphate phase of ALTAPORE is similar to human cancellous bone and is designed to promote enhanced bone growth. (baxter.com)
The aim of this study was to evaluate if a synthetic fully resorbable tri-calcium phosphate-based substitute can provide adequate mechanical stability when employed to restore severe, contained defects, in comparison with morselized bone graft. (unime.it)
Five cadaveric pelvises were adopted, one side was reconstructed with morselized bone graft and the other with the synthetic substitute, consisting of dense calcium phosphate granules within a collagen matrix. (unime.it)

The use of graft materials to heal bone defects has been known for a long time. (medindia.net)
Loss of a key protein leads to defects in skeletal development including reduced bone density and shortening of the fingers and toes. (medindia.net)
These defects may be the result of surgery or injury to the bone. (wraltechwire.com)
These osseous defects are surgically created or the result of traumatic injury to the bone and are not intrinsic to the stability of the bony structure. (baxter.com)
Surgical handiness allows to fit the composite during the operation to the shape of individual bone defects by cutting or bending. (flexioss.pl)
All groups showed new bone formation from the periphery to the center of the defects, and the group nano-Sr with a lesser extent among those studied. (bvsalud.org)
These findings indicate that the Mastergraft artificial bone induced osteogenesis in the jawbone and seemed effective for repairing bone defects. (elsevierpure.com)
Bone grafts are commonly used in orthopedic and dental surgeries to promote bone healing, fill bone defects, and provide structural support. (kikyus.net)
Revision surgery aims to repair such defects before implantation by means of reconstruction materials, whose morselized bone graft represents the gold standard. (unime.it)
Overall, the synthetic substitute provided adequate mechanical stability in comparison with morselized bone graft, thus representing a reliable alternative to treat severe, contained acetabular defects. (unime.it)
The grafting materials were implanted in standardized 8 mm circular bicortical bone defects in rabbit calvariae. (dpapavasileiou.gr)
Defects treated with β-TCP/CS showed the greatest bone regeneration and graft resorption, although differences between groups were not statistically significant. (dpapavasileiou.gr)
In conclusion, the novel β-TCP/CS grafting material performed well as a bioactive and biomimetic alloplastic bone substitute when used in cranial defects in this animal model. (dpapavasileiou.gr)
It can be used clinically for all types of bone defects, eliminating the tedious surgical procedures and the psychological stress of the medical staff. (ad-c.org)
Bone grafting is a common procedure used to repair bone defects, promote bone growth, and facilitate the healing process in cases of fractures, bone loss, spinal fusion surgeries, and orthopedic treatments. (credenceturbine.com)
A bone graft is surgery to place new bone or bone substitutes into spaces around a broken bone or bone defects. (medlineplus.gov)
Objective: The present study aims to develop a histological descriptive analysis on the repair of bone defects filled with β-TCP, associated to pure titanium implants into cavities prepared in the calvarial bone of rats. (bvsalud.org)
Four bone defects were made into each one of the calvarial bones of rats and filled with: (a) β-TCP, (b) clot, (c) β-TCP + pure titanium screw, and (d) pure titanium screw. (bvsalud.org)

Areas of bone formation were detected in close contact with biomaterials. (bvsalud.org)
Novel bone substitute biomaterials should have a property not only to support cellular attachment on the material surfaces but also activate cellular function of osteoblasts that promote regeneration of bone tissue. (tohoku.ac.jp)

Older individuals often have compromised bone healing capabilities, making bone graft substitutes an essential component of their treatment and recovery. (kikyus.net)

BBS-Bioactive Bone Substitutes Plc, Company Announcement, Insider information, 20 November 2023 at 18.29 p.m. (ntb.no)
The Global Synthetic Dental Bone Graft Substitute market is anticipated to rise at a considerable rate during the forecast period, between 2023 To 2030. (marketreportsinsights.com)

The use of bone grafts and substitutes reduces the need to harvest autograft bones from patients, which in turn reduces postoperative pain and healing time. (medgadget.com)
The report also profiles key players involved in the global Bone Grafts and Substitutes Market , such as Arthrex, Inc., Baxter International Inc., Integra LifeSciences Holdings Corporation, Johnson & Johnson (DePuy Synthes), Medtronic Plc. (medgadget.com)
The report states that the global Bone Grafts And Substitutes Market generated $2,690 million in 2017 and is projected to attain $3,912 million by 2025, growing at a CAGR of 4.8% during the forecast period, 2018-2025. (medgadget.com)
The development of biocompatible synthetic bone grafts and a shift from autograft to the allograft, owing to rapid technological advancement, have increased the demand for bone grafts and substitutes worldwide. (medgadget.com)
The report segments the global bone grafts and substitutes market by type, application, and geography. (medgadget.com)
A vast range of bone grafts and substitutes is available for clinical use. (inkwoodresearch.com)

You'll also get some of that marrow in the middle of the bone to help thicken the sauce. (metafilter.com)
The product is combined with bone marrow from the patient and then packed into the area that needs to be repaired. (wraltechwire.com)
The precise handling characteristics of ALTAPORE allow the product to be molded into multiple shapes to adapt to various surgical needs when using as standalone, with autograft, or bone marrow aspirate. (baxter.com)
ALTAPORE is an implant intended to fill bony voids or gaps of the skeletal system (i.e., extremities, pelvis and posterolateral spine) and can be used by itself, with autograft as a bone graft extender or with autogenous bone marrow aspirate. (baxter.com)
Four weeks after the operation, part of each implant was already resorbed and the resorbed area was replaced by newly formed bone tissue and bone marrow. (elsevierpure.com)
In 1988, a study of ten people with debilitating pain in the hips and knees discovered a condition that the researchers called bone marrow edema . (medicalnewstoday.com)
People with hip and knee pain were found to have altered bone marrow density on a magnetic resonance imaging ( MRI ) scan that was not visible when examined by X-ray. (medicalnewstoday.com)
Bone marrow edema is now usually referred to as "bone bruise" to reflect the traumatic nature of the condition. (medicalnewstoday.com)
Recently, a technique for insufflating bone substitute into the bone marrow lesions of the knee, Subchondroplasty (Zimmer Knee Creations, Exton, PA), has led to promising results. (manhattansportsdoc.com)
Bone marrow from the posterior superior iliac crest was examined. (cdc.gov)
Aspirates and cytogenic evaluation of cultured cells of bone marrow were all normal. (cdc.gov)
The test may be performed by mixing the patient's plasma, serum, or serous effusions as a source of LE factor with bone marrow from a donor subject. (medscape.com)
LE cells were observed in the bone marrow of patients with lupus. (medscape.com)

However, cell-based matrices (CBM) segment is expected to grow at the highest rate, a CAGR of 6.1%, during the forecast period, as these materials serve as a cell-based bone grafts substitutes that use cells to generate tissue alone or in combination with support matrix. (medgadget.com)
creos xenogain collagen - a xenogenic bone substitute (deproteinized bovine bone mineral) embedded in 10% porcine type 1 collagen, indicated for guided bone regeneration (GBR) and guided tissue regeneration (GTR) procedures. (nobelbiocare.com)
High specific surface area (due to the high microporosity of granules), high ionic reactivity (adsorption of calcium and phosphate ions from surroundings liquid which allows to increase the rate of mineralization within the implantation site and increase the rate of new bone tissue formation). (flexioss.pl)
This simplifies the nutrient supply to the biomaterial within the implantation site and removal of metabolic degradation products, thus increasing the rate of bone tissue regeneration. (flexioss.pl)
This can happen, for example, after removal of tumors or infected bone tissue. (bonalive.com)
The bone graft substitutes market refers to the market for products used to replace or augment bone tissue in patients who require bone graft procedures. (kikyus.net)
Traditionally, bone grafts involved the transplantation of autografts (bone tissue taken from the patient's own body), allografts (bone tissue sourced from a human donor), or xenografts (bone tissue sourced from animals). (kikyus.net)
These advancements include the introduction of bioactive materials, tissue engineering techniques, and the incorporation of growth factors and stem cells into graft substitutes. (kikyus.net)
At 12 weeks after the operation, residual globular-shaped β-TCP granules composed of rod-shaped particles were resorbed into compact petrotic bone tissue almost completely. (elsevierpure.com)
The formation of less compact petrotic bone tissue was observed in specimens implanted with globular-shaped β-TCP granules composed of conventional non-rod-shaped particles. (elsevierpure.com)
Commercially available β-TCP granules composed of conventional non-rod-shaped particles were mostly resorbed into trabecular bone and the formation of compact petrotic bone tissue was rarely observed. (elsevierpure.com)
Due to the limited availability of bone tissue, synthetic substitutes are also used. (unime.it)
ICD-10-PCS code 0PUQ07Z for Supplement Left Metacarpal with Autologous Tissue Substitute, Open Approach is a medical classification as listed by CMS under Upper Bones range. (aapc.com)
Bruises can occur in bones as well as soft tissue. (medicalnewstoday.com)
Bone bruise pain lasts longer than pain from a soft tissue injury. (medicalnewstoday.com)
After eight weeks of healing, the animals were euthanized and the bone tissue was analyzed using histology and micro-computed tomography (micro-CT). (dpapavasileiou.gr)
They provide a scaffold for new bone growth and are gradually replaced by the patient's own bone tissue. (credenceturbine.com)
These materials eventually degrade, leaving behind new bone tissue. (credenceturbine.com)
Presence and volume of loose connective tissue and newly formed bone tissue were analyzed, as well as the presence or absence of remaining material (β-TCP) into the defect. (bvsalud.org)

This is the first long-term pharmacokinetic study that reports vancomycin release from a biphasic injectable ceramic bone substitute. (boneandjoint.org.uk)
Injectable bone substitutes (IBS) represent compelling options for bone regenerative medicine as they can be used to optimally fill a complex bone defect through minimally invasive intervention. (mad4am.fr)
Randomized clinical study of injectable dextrin-based hydrogel as a carrier of a synthetic bone substitute. (bvsalud.org)
CLINICAL RELEVANCE This study validates DEXGEL Bone safety and performance as an injectable carrier of granular bone substitutes for alveolar ridge preservation. (bvsalud.org)

Insight On Synthetic Bone Graft Substitutes Market: Share, Size, Insights 2022. (postingsea.com)
According to the Market Statsville Group (MSG), the global bone grafts & substitutes market was valued at USD 2.5 billion in 2021 and is projected to reach USD 3.5 million by 2030, registering a CAGR of 4.3% from 2022 to 2030. (kikyus.net)

Bone graft substitutes play a vital role in the treatment and management of these disorders, as they facilitate bone healing and regeneration. (kikyus.net)
They are often used in procedures where the goal is to facilitate bone regeneration without leaving a permanent implant. (credenceturbine.com)
Growth Factors: Some synthetic bone graft substitutes are combined with growth factors to enhance bone regeneration by stimulating the body's natural healing processes. (credenceturbine.com)
Further evaluation of the molecular mechanisms responsible for this increased osteoinductivity at an early stage in the regeneration process indicated that the CHA+BMP-2/7 enhanced progenitor cell homing at the implantation site, upregulated the key transcriptomic determinants of bone formation, and increased the production of bone extracellular matrix components. (lu.se)

Based on the type, the report categorizes the market into allograft, bone graft substitutes, and cell-based matrices. (medgadget.com)
Over the years, advancements in technology and biomaterial science have facilitated several bone graft types from different sources, such as synthetic materials (alloplastic graft), human cadavers (allograft), and animals (xenograft). (inkwoodresearch.com)
Autograft and allograft have both been associated with complications and the use of bone substitute wedges has been advocated to improve the outcome. (openorthopaedicsjournal.com)
SUMMARY OF BACKGROUND DATA: Ever since the introduction of allograft as a substitute for autologous bone in spinal surgery, a sea of literature has surfaced, evaluating both established and newly emerging fusion alternatives. (spinaldisccenter.com)
Or, it can be taken from frozen, donated bone (allograft). (medlineplus.gov)

Zavation β-TCP Bone Graft Substitute is microporous and macroporous composed of beta-tricalcium phosphate. (zavation.com)
Bioactive alloplastic materials, like beta-tricalcium phosphate (β-TCP) and calcium sulfate (CS), have been extensively researched and are currently used in orthopedic and dental bone regenerative procedures. (dpapavasileiou.gr)

Strontium ions are known to reduce bone resorption, induce osteoblastic activity and thus stimulate bone formation. (bvsalud.org)
DEXGEL Bone exhibited increased granule resorption (p = 0.029) accompanied by a tendency for more new bone ingrowth (although not statistically significant) compared to the BL® group. (bvsalud.org)
Serum bone alkaline phosphatase is a marker of bone formation and urinary N-telopeptides are markers of bone resorption. (cdc.gov)

A process by which bone implant materials can be synthesized from waste eggshells has been developed by researchers of Indian Institute of Technology (NIT) Hyderabad and Dr. B.R. Ambedkar National Institute of Technology (NIT) Jalandhar. (medindia.net)
Net proceeds from the Offering will be used inter alia for successful completion of the ongoing CE marking application process for BBS' bone implant ARTEBONE® Paste, for initiating the commercialisation of ARTEBONE® Paste and for paying the loan repayments and interest. (ntb.no)
BBS is applying for the CE marking for its first product, ARTEBONE® Paste bone implant. (ntb.no)
Although bone grafting is a large-scale practice in dentistry, implant failure due to loosened or poor fixation of implanted grafts is a common complication. (inkwoodresearch.com)
Bone/implant motions were measured through Digital Image Correlation and were expressed in terms of permanent and inducible translations and rotations. (unime.it)
After 6 months, a bone biopsy of the grafted area was collected for histological and histomorphometric evaluation, prior to implant placement. (bvsalud.org)
The addition of DEXGEL to BL® granules did not compromise bone volume or density, being even beneficial for implant primary stability (p = 0.017). (bvsalud.org)

Increased use of bone graft substitutes facilitates minimally invasive surgeries and short surgical procedures. (medgadget.com)
ALTAPORE MIS System is designed to assist surgeons who want a simple, ready-to-use bone grafting system for open and minimally invasive procedures. (baxter.com)
The demand for bone graft substitutes is driven by the need for minimally invasive treatment options. (kikyus.net)

However, astronomical cost of surgeries along with ethical issues related to bone grafting procedures impede market growth. (medgadget.com)
ALTAPORE bioactive bone graft substitute enables surgeons to think creatively while providing the enhanced porosity and adaptability that today's challenging orthopedic surgeries require. (baxter.com)
Bone graft substitutes offer an alternative that eliminates the need for additional surgeries and potential complications associated with autograft harvest. (kikyus.net)
Not all bone graft surgeries require the use of bone stimulators. (medlineplus.gov)

Regulatory agencies, such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), provide guidelines for the approval and commercialization of bone graft substitutes. (kikyus.net)
Despite the glimmer of hope provided by the discovery and commercialization of bone morphogenetic protein-2 (BMP-2) as a bone graft substitute, side effects related to the use of supraphysiological doses have hindered its clinical usage. (lu.se)

Sushruta Samhita, an ancient Sanskrit text on medicine and surgery, describes 'Asthipoorana' or bone grafting in which materials having calcium were combined with the latex of the banyan tree to form bone substitutes. (medindia.net)

It has refined the material's properties and made it more compatible with natural bone. (medindia.net)
Will gradually generate new natural bone. (primedentalsupply.com)

A recent study by Fact.MR on the dental membrane and bone graft substitutes market offers a 10-year forecast for 2021 to 2031. (pharmiweb.com)

Porous structure supports new bone growth. (zavation.com)
Polymers: Biodegradable synthetic polymers, like polylactic acid (PLA) and polyglycolic acid (PGA), are used to create porous scaffolds that promote bone cell attachment and growth. (credenceturbine.com)

This technique creates a wedge shaped defect in the bone, which can be managed either by leaving to heal or grafting with bone, bone substitute or other synthetic materials. (openorthopaedicsjournal.com)
Depending on many factors, such as the patient's age and background, defect type, site and size, additional material might be needed to fill the cavity and help the bone heal itself. (bonalive.com)
Octacalcium phosphate/gelatin composite (OCP/Gel) enhances bone repair in a critical-sized transcortical femoral defect rat model. (tohoku.ac.jp)
Collagen gel/TTCP/MCPM/ and growth factor materials are mixed in the cavity and then combined with innovative instruments to fill the bone defect directly. (ad-c.org)
During surgery, the surgeon makes a cut over the bone defect. (medlineplus.gov)
The bone graft can be taken from areas close to the bone defect or more commonly from the pelvis. (medlineplus.gov)
Recovery time depends on the injury or defect being treated and the size of the bone graft. (medlineplus.gov)
Most bone grafts help the bone defect heal with little risk of graft rejection. (medlineplus.gov)

However, the joint reconstruction segment is projected to grow at the fastest rate during the forecast period, registering a CAGR of 6.2%, due to an upsurge in incidences of bone and joint disorders. (medgadget.com)
According to Fact MR's recent market research, sales of Dental Membrane and Bone Graft Substitutes to swell at propelled CAGR through 2031, as investment towards expansion of healthcare infrastructure continues rising. (pharmiweb.com)

The reconstruction types exhibited a similar behavior, consisting of an initial settling trend followed by failure as bone fracture (i.e., no failure of the reconstruction material). (unime.it)

The study identifies crucial trends that are determining the growth of Dental Membrane and Bone Graft Substitutes market. (pharmiweb.com)
This report explicates recent market developments, strategic market growth analysis, market size, category market growths, product approvals, product launches, geographical expansions, and technological innovations associated with dental membrane and bone graft substitutes market. (pharmiweb.com)
First, he notes the typically increasing financial circumstances next, he points out company earnings growth third, are the traditionally small fascination rates, as the Fed sticks to its in close proximity to-zero rate coverage and ultimately, there is TINA, or 'there is no substitute. (floschi.info)
The technology, based on growth factor extract from reindeer bones, improves bone formation in bone healing problems. (lifesciencemarketresearch.com)
With enhanced micro and macro porosity and silicon content shown to be optimal for bone formation, ALTAPORE is designed to promote early vascularization, increase cellular activity, and enhance bone growth as demonstrated in pre-clinical and in-vitro studies. (baxter.com)
Thus, the biomaterial may resemble (in its properties) very expensive bone-substitutes containing BMP-2-type growth factors. (flexioss.pl)
The extensive documentation of the Synthetic Dental Bone Graft Substitute industry gives access to all the factors expected to influence the growth prospect of the business worldwide. (marketreportsinsights.com)
New bone growth occurs, and damaged bone is repaired or removed. (bonalive.com)
The 'diamond concept' is a framework describing 4 integral factors of bone healing: osteoconductive scaffolds, growth factors, mechanical environment, and osteogenic cells. (bonalive.com)
The bone graft substitutes market is driven by various dynamics that shape its growth and development. (kikyus.net)
These technologies have improved the efficacy and safety of bone graft substitutes, thereby driving market growth. (kikyus.net)
All clinical studies reporting radiological and/or patient outcomes following the use of bone substitutes were reviewed under the broad categories of Allografts, Demineralized Bone Matrices (DBM), Ceramics, Bone Morphogenic proteins (BMPs), Autologous growth factors (AGFs), Stem cell products and Synthetic Peptides. (spinaldisccenter.com)
These are machines that can be worn over the surgical area to stimulate bone growth. (medlineplus.gov)

The global orthobiologics company plans to launch its SIGNAFUSE Bioactive Bone Graft in a new strip format in the next few months. (wraltechwire.com)
SIGNAFUSE Bioactive Bone Graft is intended for use in bony empty spaces or gaps in the skeletal system that aren't required for bone stability. (wraltechwire.com)
We are excited to expand our portfolio of bone graft solutions with the SIGNAFUSE Bioactive Bone Graft strip," said Megan Osorio, Bioventus' marketing vice president. (wraltechwire.com)
The system combines extended reach, controlled delivery and precise bone graft placement in a specially designed applicator with ALTAPORE Bioactive Bone Graft Substitute. (baxter.com)

OBJECTIVE: Compared to autologous bone grafts, allogeneic bone grafts integrate slowly, which can adversely affect clinical outcomes. (jefferson.edu)

Whereas autologous bone graft from intraoral donor site and alloplastic bone graft received the lowest rejection rates, at 24.5% and 6.3%, respectively. (inkwoodresearch.com)
For alloplastic bone graft and xenograft, the country of origin was the major predictor for rejection. (inkwoodresearch.com)

Besides this, Dental Membrane and Bone Graft Substitutes market will continue gaining from increasing willingness among patients and families to spend on advanced healthcare. (pharmiweb.com)
Adoption of care model innovation in healthcare will have a profound impact on the Dental Membrane and Bone Graft Substitutes market. (pharmiweb.com)
The report offers actionable and valuable market insights of Dental Membrane and Bone Graft Substitutes. (pharmiweb.com)
The report also includes information on the sales and demand of Dental Membrane and Bone Graft Substitutes Market across various industries and regions. (pharmiweb.com)
The study also provides the dynamics responsible for influencing the future status of the dental membrane and bone graft substitutes market over the forecast period. (pharmiweb.com)

Orthopedic and trauma surgeons are regularly confronted with situations where an empty cavity remains in the patient's bone. (bonalive.com)

ALTAPORE achieves fusion rates on par with autograft-the gold standard in bone fusion. (baxter.com)
The use of DBM as a bone expander to augment autograft is supported, especially in the lumbar spine. (spinaldisccenter.com)
A bone graft can be taken from the person's own healthy bone (this is called an autograft). (medlineplus.gov)

What are the pros and cons of different types of bone graft substitutes? (bonalive.com)
Jumping or impact from running on hard surfaces can cause all three types of bone bruise. (medicalnewstoday.com)

Either a compressive force that crushes the cells and separates the cartilage and underlying bone, or a rotational twisting force triggers subchondral lesions. (medicalnewstoday.com)

The report not only offers hard to find facts about the trends and innovation driving the current and future of Synthetic Dental Bone Graft Substitute business, but also provides insights into competitive development such as acquisition and mergers, joint ventures, product launches and technology advancements. (marketreportsinsights.com)

By stimulating new bone formation through osteostimulation*, Bonalive® S53P4 bioactive glass induces a high but balanced local bone turnover. (bonalive.com)

Histological assessment of 17 cases confirmed adequate bone replacement of the Triosite although some areas of tricalcium phosphate remained visible. (openorthopaedicsjournal.com)

An increase in the prevalence of bone and joint disorders have garnered the bone graft substitutes segment to generate maximum revenue in 2016. (medgadget.com)
Spinal fusion accounted for the major share of the total market in 2016, as bone grafts and their substitutes are widely used in the spine fusion procedures worldwide. (medgadget.com)
METHODS: A Medline search of English language literature published through March 2016 discussing bone graft substitutes and fusion extenders was performed. (spinaldisccenter.com)

This study involved a histologic, enzyme histologic, immunohistologic, and three-dimensional microstructure evaluating the extent of osteogenesis and repair in the human alveolar extraction socket achievable with an artificial bone substitute. (elsevierpure.com)
The performance of DEXGEL Bone and BL® treatments on alveolar preservation were further analyzed by computed tomography and Hounsfield density analysis . (bvsalud.org)

The growing prevalence of these conditions contributes to the demand for bone graft substitutes. (kikyus.net)
As the elderly population grows, the demand for bone graft substitutes is expected to rise. (kikyus.net)

Revenue forecasts to 2030 for 5 regional and 17 key national markets - See forecasts for the Dental Bone Graft Substitutes market in North America, Latin America, Europe, Asia-Pacific and MEA. (visiongain.com)
North America has a mature healthcare infrastructure and is a key market for synthetic bone graft substitutes. (credenceturbine.com)

As many of you noted, this case posed issues that affected the patient's bone health beyond her age-related osteoporosis and use of alendronate. (medscape.com)

Opening wedge high tibial osteotomy often requires bone grafting to improve the union rate and avoid instability at the osteotomy site. (openorthopaedicsjournal.com)

Class I IBS, taking advantage of ceramic particles or granules as the support for bone formation, are already commercialized and widely employed in clinics. (mad4am.fr)
BL® granules (250-500 µm) were administered to 6 randomized participants whereas the other 6 received DEXGEL Bone . (bvsalud.org)

Factors such as a large aging population, high prevalence of bone-related conditions, and advanced medical technologies drive the demand for these substitutes. (credenceturbine.com)

The segment is expected to dominate the global market through 2025, owing to advancements in bone graft materials and the development of innovative products. (medgadget.com)
Where is the Dental Bone Graft Substitutes market heading? (visiongain.com)
Much opportunity remains in this growing Dental Bone Graft Substitutes Market. (visiongain.com)
The report also includes profiles and for some of the leading companies in the Dental Bone Graft Substitutes Market, with a focus on this segment of these companies' operations. (visiongain.com)
Overall world revenue for Dental Bone Graft Substitutes Market will surpass $xyz million in 2020, our work calculates. (visiongain.com)
The Synthetic Dental Bone Graft Substitute market is segmented on the basis of Types, Applications, Key Companies, Regions & Countries. (marketreportsinsights.com)
Regulatory Environment: The bone graft substitutes market is subject to regulatory oversight to ensure patient safety and product efficacy. (kikyus.net)
Cost Considerations: The cost-effectiveness of bone graft substitutes is a significant factor influencing market dynamics. (kikyus.net)
Competitive Landscape: The bone graft substitutes market is highly competitive, with numerous manufacturers and suppliers vying for market share. (kikyus.net)
Synthetic Bone Graft Substitutes Market pertains to the medical industry's focus on developing and supplying synthetic materials that can serve as substitutes for traditional bone grafts in various medical procedures. (credenceturbine.com)
Synthetic Bone Graft Substitutes Market exhibits varying trends and dynamics across different regions globally. (credenceturbine.com)
Europe is another significant market for synthetic bone graft substitutes. (credenceturbine.com)

However, advancements in medical technology have led to the development of synthetic bone graft substitutes. (kikyus.net)
Technological Advancements: The field of bone graft substitutes has witnessed significant technological advancements, leading to the development of innovative products. (kikyus.net)

OBJECTIVE: This manuscript intends to provide a review of clinically relevant bone substitutes and bone expanders for spinal surgery in terms of efficacy and associated clinical outcomes, as reported in contemporary spine literature. (spinaldisccenter.com)

The surgery consisted of tunneling procedure to elevate the maxillary edentulous ridge periosteum, followed by the insertion of bone graft. (jefferson.edu)
Whereas the general disease transmission risk is significantly low, attributed to the quality care administered during the bone graft-obtaining procedure, which has considerably improved over the years. (inkwoodresearch.com)
Defattening is an important procedure carried out so as to prevent the bones from looking dirty, attracting dust and also to make bleaching easier. (ispub.com)

Accordingly, rigorous research efforts have been centered on developing innovative bone substitutes that offer immediate mechanical support alongside ensuring appropriate graft anchoring. (inkwoodresearch.com)

On micro-computed tomography, new bone was observed in all collected samples, and osteogenesis was observed to have taken place around the artificial bone substitute. (elsevierpure.com)

Bone substitute wedges often appear as well delineated areas on radiographs several years following the osteotomy and this failure of full incorporation raises the question of the mechanical strength of the tibia and whether it will be suitable to undergo conversion to a total knee replacement when required. (openorthopaedicsjournal.com)

The industry experts have left no stone unturned to identify the major factors influencing the development rate of the Synthetic Dental Bone Graft Substitute industry including various opportunities and gaps. (marketreportsinsights.com)
When studying the micro markets the researchers also dig deep into their future prospect and contribution to the Synthetic Dental Bone Graft Substitute industry. (marketreportsinsights.com)

Bioactivating a bone substitute accelerates graft incorporation in a m" by Jinlong Chen, Xue Yuan et al. (jefferson.edu)

The skeletal system is developed and maintained by two continuous processes: bone modeling and remodeling. (bonalive.com)

The research seeks to produce bone substitute materials such as I-tricalcium phosphate (I-TCP), a commonly-used bone substitute material from natural sources, without the use of toxic chemicals, NIT Hyderabad said on Wednesday. (medindia.net)
Biocompatible (chemical composition similar to bone material. (zavation.com)
The material can then be polished and color-matched to create a deceptively authentic-looking ivory substitute. (materialstoday.com)
Instead of painstakingly carving them out of the ivory substitute material, objects can now be printed in a matter of hours. (materialstoday.com)
is a bone graft material intended to be used to reconstruct bony loss or bone gaps in maxillofacial applications. (primedentalsupply.com)
To make space for bone ingrowth, the material needs to be bio-absorbable. (bonalive.com)
We present the technique of acetabular Subchondroplasty, in which a bone substitute material is injected into subchondral acetabular cysts under fluoroscopic guidance. (manhattansportsdoc.com)

Evaluation of bone mineral status can utilize measures of total bone mineral content and bone mineral density. (cdc.gov)
In patients with such a history or who fail to at least maintain bone mineral density while on a bisphosphonate, consideration should be given to switching to a drug such as denosumab. (medscape.com)

Ceramics (40 studies) and Allografts (39 studies) were the other two highly published groups of bone substitutes. (spinaldisccenter.com)

Anatomy9

Organisms1

Diseases7

Chemicals and Drugs13

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Phenomena and Processes13

Technology, Industry, Agriculture10

Hydroxyapatite7

Calcium phosphate3

Defects18

Biomaterials2

Making bone graft substitutes1

20232

Grafts and substitutes6

Marrow13

Tissue19

Injectable4

20222

Regeneration4

Allograft5

Beta-tricalcium phosphate2

Resorption3

Implant7

Minimally3

Surgeries4

Commercialization of bone2

Having calcium1

Natural bone2

20211

Porous2

Defect8

CAGR2

Reconstruction1

Growth13

Bioactive Bone Graft4

Autologous bone grafts1

Alloplastic bone2

Membrane5

Orthopedic1

Autograft3

Types of bone2

Cartilage and unde1

Insights1

Stimulating new bone formation1

Histological1

20163

Alveolar2

Demand for bone2

North America2

Patient's bone1

Wedge high tibial osteotomy1

Granules2

Prevalence1

Market12

Advancements2

Clinically1

Procedure3

Innovative bone1

Micro-computed tomography1

Mechanical1

Dental bone2

Incorporation1

Skeletal system1

Material7

Density2

Allografts1