Myeloproliferative DisordersMyelodysplastic-Myeloproliferative DiseasesMyelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicAnemia, RefractoryThrombocytosisAnemia, SideroblasticPolycythemia VeraJanus Kinase 2Primary MyelofibrosisThrombocythemia, EssentialLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemia, Myelomonocytic, JuvenileSplenomegalyHematopoiesis, ExtramedullaryBone MarrowFusion Proteins, bcr-ablReceptors, ThrombopoietinGenes, ablLeukocytosisOncogene Proteins, FusionBone and BonesSTAT5 Transcription FactorHematopoietic Stem CellsLeukemia, Myeloid, AcuteBone Marrow TransplantationBone Marrow Cellsfms-Like Tyrosine Kinase 3MutationGene Expression Regulation, LeukemicCell Transformation, NeoplasticLeukemiaAnemia, Refractory, with Excess of BlastsBenzamidesHematopoiesisMyeloid CellsRetroviridaePyrimidinesTranslocation, GeneticLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeBone RemodelingReceptors, ErythropoietinBone Marrow NeoplasmsMutation, MissenseMice, Inbred C57BLPiperazinesLeukemia, MyeloidDisease Models, AnimalSignal TransductionProtein-Tyrosine KinasesTransduction, GeneticCell ProliferationMice, KnockoutProto-Oncogene ProteinsChromosomes, Human, Pair 5Bone DensityPhenotypeLeukemia, Neutrophilic, ChronicFlow CytometryMice, Inbred BALB CMice, TransgenicMegakaryocytesBone ResorptionCells, CulturedBone Marrow DiseasesBlast CrisisKaryotypingGranulocytesSarcoma Viruses, MurinePreleukemia