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  • Mineral Density
  • It has been observed that higher serum-osteocalcin levels are relatively well correlated with increases in bone mineral density (BMD) during treatment with anabolic bone formation drugs for osteoporosis, such as Teriparatide. (wikipedia.org)
  • osteocalcin
  • In many studies, osteocalcin is used as a preliminary biomarker on the effectiveness of a given drug on bone formation. (wikipedia.org)
  • Scaffold
  • NASDAQ: WMGI), a global orthopaedic medical device company, today announced a supply and distribution agreement with AlloSource for FUSIONFLEX[TM] Bone Matrix , a unique bone repair scaffold for use in primary fusion procedures of the foot and ankle, as well as other orthopaedic bone grafting applications. (thefreedictionary.com)
  • The mechanical and physical properties of the scaffolds (porosity, compressive strength, solubility) and their potential to facilitate homogenous colonization by osteogenic cells and extracellular bone matrix formation throughout the porous scaffold architecture prior to in vivo implantation were examined. (scientific.net)
  • More particularly, this invention relates to a superior collagenous bone matrix useful as a xenogenic implant for use as an osteogenic device, as a bone particle coating for implantable prostheses, as a delivery vehicle for the in vivo sustained release of protein, and as a scaffold for anchorage-dependent cells. (google.com)
  • The processing of the bone sweeps off the osteoinductive and osteogenic capabilities of the graft, thus leaving just an osteoconductive scaffold behind. (qyresearchgroups.com)
  • Bone generally has the ability to regenerate completely but requires a very small fracture space or some sort of scaffold to do so. (wikipedia.org)
  • Osteoconduction occurs when the bone graft material serves as a scaffold for new bone growth that is perpetuated by the native bone. (wikipedia.org)
  • alveolar bone
  • Alveolar bone reconstruction with a DFDBM allograft mixed with calcium sulphate graft binder was performed immediately. (jcda.ca)
  • Posterior mandibular extraction sites with compromised buccal alveolar bone may be effectively managed by immediate alveolar augmentation using a mixture of DFDBM allograft and calcium sulphate graft binder. (jcda.ca)
  • A question of interest to general practitioners and specialists working in endosseous implantology is how to approach reconstruction of a postextraction alveolar bone defect. (jcda.ca)
  • osteoprogenitor cells
  • Cell-rich cancellous bone is processed to selectively deplete immunogenic components from the hematopoietic stem cell lineage (e.g. blood cells, lymphocytes,and osteoclasts), while retaining viable MSCs and osteoprogenitor cells. (lifemapsc.com)
  • regeneration
  • Abstract: This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate chitosan block bone and chitosan membrane on the regeneration of 1- wall intrabony defects in the beagle dogs. (scientific.net)
  • Chitosan membrane group significantly enhanced bone regeneration compared to control, CaP-chitosan block bone and combination group. (scientific.net)
  • To compare bone regeneration in the critical-sized bone defects grafted with demineralized bone matrix, platelet-rich fibrin, and hyaluronic acid in rats. (ovid.com)
  • The sole usage of HA does not effectively increase bone regeneration when compared with DBM and PRF. (ovid.com)
  • The DBM and PRF do not have superiority to each other in the bone regeneration while they are superior to HA. (ovid.com)
  • The company focusses on bone regeneration. (wikipedia.org)
  • mineral
  • Disclosed is a matrix material for implantation in a mammalian host comprising biocompatible mineral-free type I bone collagen, xenogenic to the host, and biodegradable therewithin. (google.com)
  • Journal of Bone and Mineral Research. (wikipedia.org)
  • Osteonectin also shows affinity for collagen in addition to bone mineral calcium. (wikipedia.org)
  • Homozygous mutant animals had unusually white incisors, decreased bone mineral density, abnormal lens morphology, cataracts and a decreased length of long bones. (wikipedia.org)
  • synthetic
  • Washington, Nov 20 (ANI): In a breakthrough study, scientists have found that a synthetic bone matrix could offer hope for babies born with craniosynostosis- a condition that causes the plates in the skull to fuse too soon. (thefreedictionary.com)
  • If so, should an autogenic, allogeneic, xenogeneic or synthetic bone graft material, or a combination of these products, be used for the reconstruction? (jcda.ca)
  • CalMatrix bone graft binder (Citagenix Inc.) is a synthetic putty-like calcium sulphate bone graft binder containing calcium sulphate ╬▒-hemihydrate, sodium carboxymethyl cellulose and a hydrating solution. (jcda.ca)
  • implant
  • The demineralized bone matrix (DBM) Strip implant primarily is used for posterior lumbar fusion, a surgical procedure intended to promote bone fusion along the posterior elements of the spine. (thefreedictionary.com)
  • In situ gel forming implant in vivo was successfully fabricated by simple subcutaneous injection of chitosan and GP solutions with demineralized bone matrix (DBM). (scientific.net)
  • Dental implant has proven to be a reliable long-term rehabilitation treatment showing considerable success rate and it is known that its stability depends on the bone quantity and quality present at the treated site. (alliedacademies.org)
  • The bone samples analyzed were obtained in the preparation phase for implant placement. (alliedacademies.org)
  • This case series reports short- and long-term healing, before and after placement of an implant, in posterior mandibular extraction sites grafted with demineralized, freeze-dried bone matrix (DFDBM) allograft mixed with calcium sulphate graft binder. (jcda.ca)
  • Upon exposure and implant placement, the grafted alveolar ridge in all patients presented appropriately sized, dense and well-vascularized bone, wide enough to receive the planned wide-platform implant. (jcda.ca)
  • In particular, should the graft be placed at the time of extraction, to avoid the possibility of poor bone healing (which would necessitate grafting when the implant is placed)? (jcda.ca)
  • cells
  • Bone-forming cells are clearly visible lining the walls. (innovations-report.com)
  • Stem cells may be an alternative to an autograft because they have the potential to grow into a variety of cells and may help promote bone fusion. (spinerf.org)
  • The Spinal Research Foundation participated in a clinical trial that evaluated the effectiveness of Trinity Evolution bone matrix, an allograft that consists of bone chips with viable adult stems cells and bone precursor cells. (spinerf.org)
  • Trinity Evolution allograft can be preferable to autografts because of the higher number of bone-forming cells per volume and less associated surgical time and blood loss. (spinerf.org)
  • All components of each lot of Osteocel are from the same donor, and the cells are not removed from their native matrix. (lifemapsc.com)
  • 6. The matrix of claim 3 wherein the particles define interstices dimensioned to permit influx, proliferation and differentiation of migratory cells from the body of said mammalian host. (google.com)
  • Osteonectin also increases the production and activity of matrix metalloproteinases, a function important to invading cancer cells within bone. (wikipedia.org)
  • Individual cells cannot make bone. (wikipedia.org)
  • calcium
  • The surgical control group received a flap operation only, while experimental group was treated with calcium phosphate chitosan block bone and/or chitosan membrane. (scientific.net)
  • stimulate
  • Researchers have used fluid flow to stimulate bone growth before, but no one has looked at its effect on three-dimensional cultures that have been subjected to continuous stimulation for several days," said Tony Mikos, the John W. Cox Professor of Bioengineering. (innovations-report.com)
  • 1998
  • In January, 1998, Osteotech filed its initial patent infringement suit against GenSci accusing it of violating claims of a patent issued to Osteotech involving the company's Grafton Demineralized Bone Matrix products. (thefreedictionary.com)
  • In January 1998, Osteotech filed its initial suit against GenSci accusing it of violating claims of a patent issued to Osteotech involving the company's Grafton Demineralized Bone Matrix process, by making, using, and/or selling the invention claimed in Osteotech's patent without permission or license from Osteotech. (thefreedictionary.com)
  • putty
  • Forty Wistar Albino rats allocated into 4 experimental groups: platelet-rich fibrin (PRF) group, noncross-linked hyaluronic acid gel (HA) group, demineralized bone matrix in putty form (DBM) group, and control group. (ovid.com)
  • Accell Connexus demineralized bone matrix putty (Citagenix Inc., Laval, QC) is composed of 70% (by weight) allogeneic demineralized, freeze-dried bone matrix (DFDBM). (jcda.ca)