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  • cancers
  • Medical oncologist Jane Churpek, MD, specializes in the diagnosis and treatment of blood cancers and also serves as co-director of the Comprehensive Cancer Risk and Prevention Clinic. (uchicagomedicine.org)
  • We're among just a few centers in the country offering CAR T-cell therapy , a new type of immunotherapy that shows promise for patients with acute lymphoblastic leukemia and other blood cancers. (uchicagomedicine.org)
  • The trial is researching the safety and efficacy of StemEx as a therapeutic treatment for patients with blood cancers like leukemia and lymphoma. (bio-medicine.org)
  • ExCell is an important trial that gives us an opportunity to investigate alternative treatments for blood cancers. (bio-medicine.org)
  • Our goal is to develop a product that will effectively treat blood cancers like leukemia and lymphoma. (bio-medicine.org)
  • Patients with leukemia, aplastic anemia and other blood disorders or cancers can be cured with a stem cell transplant. (hubpages.com)
  • Researchers have found that stem cells stored from umbilical cord can be used to treat various types of cancers, disorders and abnormalities. (stemcellumbilicalcordblood.com)
  • JERUSALEM, ISRAEL--(Marketwire - Oct. 19, 2009) - Gamida Cell announced today the publication of an article evaluating carlecortemcel-l , the generic name of what is widely known as "StemEx", as a therapy for blood cancers such as leukemia and lymphoma. (marketwired.com)
  • Gamida Cell's flagship product, StemEx, is now being studied as a therapy for patients with blood cancers in an international pivotal trial at leading transplant centers in the U.S., Europe and Israel. (marketwired.com)
  • tissue
  • These cells, which have been notoriously difficult to grow in stable quantities, are essential to any future tissue engineering efforts to combat heart disease. (news-medical.net)
  • Adipose-tissue-derived and Wharton's jelly-derived mesenchymal stromal cells suppress lymphocyte responses by secreting leukemia inhibitory factor," Tissue Engineering Part A , vol. 16, no. 11, pp. 3537-3546, 2010. (hindawi.com)
  • Tests on the cells showed they were capable of differentiating into the three fundamental layers of tissue in an early embryo. (medindia.net)
  • Most studies employing an injection of stem cells encounter swift cell death or cell washout from the target tissue," said Amanda LeBlanc, Ph.D., who led the investigation along with Stuart Williams, Ph.D., the institute's executive and scientific director. (stemcellsportal.com)
  • In an article featured in the latest issue of STEM CELLS, a research group from Stanford University describes a novel regimen for quashing this immunologic barrier - a short-course treatment with two costimlation-adhesion blockade agents, allowing engraftment of transplanted differentiated stem cells and their prolonged survival in tissue. (stemcellsportal.com)
  • To prepare for baby, one important decision to make is whether saving baby's umbilical cord blood, placental blood or cord blood tissue is right for your family. (hubpages.com)
  • Medical researchers studying umbilical cord blood stem cells have recorded several positive observations in animal studies, including instances where cord blood stem cells have improved vascular functions in injured tissue, as well as blood flow and improved overall heart function. (spiritofilithyia.com)
  • Cord tissue use is still in early research stages, and there is no guarantee that treatments using cord tissue will be available in the future. (spiritofilithyia.com)
  • Cord tissue is stored whole. (spiritofilithyia.com)
  • Additional processing prior to use will be required to extract and prepare any of the multiple cell types from cryopreserved cord tissue. (spiritofilithyia.com)
  • sickle cell di
  • such as leukemia and sickle cell disease. (wobm.com)
  • Our transplant programs offer access to highly innovative cellular treatment protocols including gene therapeutic approaches (for sickle cell disease) or cellular immunotherapy for treatment or prevention of viral diseases. (nyp.org)
  • researchers
  • But researchers and clinicians have been cautious about promoting potential therapeutic uses for these cells because the insertion of the genes could render the cells cancerous. (medindia.net)
  • Because the cells activate an immune response similar to inflammation in the presence of viral genetic material, the researchers termed the process "transflammation. (medindia.net)
  • The researchers repeated the experiment with the cell-permeable proteins, but also included an unrelated virus. (medindia.net)
  • For decades, researchers have tried to generate human pancreatic beta cells that could be cultured and passaged long term under conditions where they produce insulin. (goodnewsnetwork.org)
  • The researchers added SR1, Delta1 or both reagents with a cocktail of cytokines known to maintain stem cell renewal (IL-6, TPO, SCF, and Flt-3 ligand) and cultured cord blood cells for 14 to 16 days. (fredhutch.org)
  • The researchers then addressed the mechanism underlying this boost in stem and progenitor cell numbers by combining Delta1 and SR1. (fredhutch.org)
  • HES1 had been previously shown to block the differentiation of stem cells to myeloid progeny, and indeed the researchers were able to boost stem and progenitor cell numbers in cultured cord blood by overexpressing HES1 in combination with SR1 treatment 25-fold, recapitulating the effect seen with Delta1. (fredhutch.org)
  • The researchers then addressed whether cord blood stem cells cultured with the combination of Delta1 and SR1 increased the repopulating capability of the cells transplanted into mice. (fredhutch.org)
  • By transplanting limited dilutions of cells, the researchers found that culture with the combination of Delta1 and SR1 increased the number of rapidly repopulating cells by 3-fold over either treatment alone. (fredhutch.org)
  • In addition to myeloid cells, the researchers found SR1 alone improved B-cell repopulation better than Delta1 alone or the combination of Delta1 and SR1. (fredhutch.org)
  • Where other experiments used chemical cues to get stem cells to form cells of a single type, or to mature into a smorgasbord of cell types that the researchers would then sort through, Kusuma devised a way to get the stem cells to form the two cell types needed to build new blood vessels-and only those types. (futurity.org)
  • In the new study, researchers used two transcription factors that come together uniquely when combined to "almost exclusively" regulate arterial endothelial cell growth. (labroots.com)
  • Chinese researchers said on Wednesday they had created versatile stem cells from pigs, a ground-breaking achievement that could open up new paths for combatting human disease. (medindia.net)
  • The modified stem cells could then be used to generate pigs with the same disorder, thus providing researchers with a model on which to test new therapies. (medindia.net)
  • At Duke University, for example, researchers are using patients' own cord blood in trials for cerebral palsy and Hypoxic ischemic encephalopathy (a condition in which the brain does not receive enough oxygen). (spiritofilithyia.com)
  • embryos
  • iPS cells, which don't require human embryos, offer a possible alternative for some of the ethical dilemmas associated with stem cell research. (medindia.net)
  • These are cells that, like the coveted stem cells found in embryos, can differentiate into any type of cell in the body. (medindia.net)
  • Opponents have carefully explained why they oppose research using human embryos and support research that uses ethically unobjectionable sources, such as adult stem cells. (freerepublic.com)
  • somatic
  • It is a technical exploit because until now, no-one has been able to achieve reprogramming using somatic cells, cells that do not come from sperm or eggs, from a hooved animal. (medindia.net)
  • The language of the initiative disguises the impact of the proposal by using scientific terminology such as 'somatic cell nuclear transfer' (SCNT), without explanation to the voter who may not realize that this means human cloning. (freerepublic.com)
  • 2018
  • Representative Smith was nominated and honored with the 2018 Lives Award because of his continued support of the National Marrow Donor Program, and for his efforts in protecting patients' access to transplant," Susan Leppke, Director of Health and Public Policy at the National Marrow Donor Program/Be The Match, said. (wobm.com)
  • MIAMI, FL, Dec. 14, 2018 (GLOBE NEWSWIRE) - Five remarkable bridge-building healthcare heroes will be honored by the Regenerative Medicine Foundation (RMF) 201 9 Stem Cell and Regenerative Medicine Action Awards . (worldstemcellsummit.com)
  • As a doctor, former CEO and foundation leader, she is building bridges across sectors, culminating in the April 2018 Unite to Cure event at the Vatican. (worldstemcellsummit.com)
  • therapeutic
  • In demonstrating the ability to rebuild a microvascular bed in a clinically relevant manner, we have made an important step toward the construction of blood vessels for therapeutic use," says Sharon Gerecht, associate professor of chemical and biomolecular engineering. (futurity.org)
  • The B-Cell Lymphoma Moon Shot is revolutionizing the conventional medical research approach to rapidly translate findings into patient treatment options and develop personalized therapeutic strategies. (mdanderson.org)
  • Gamida Cell Ltd. is a world leader in stem cell expansion technologies and therapeutic products. (bio-medicine.org)
  • Regenerative Biology
  • You never know for sure that something like this is going to work until you've tested it numerous ways," said Melton, co-scientific director of the Harvard Stem Cell Institute, and the University's Department of Stem Cell and Regenerative Biology. (goodnewsnetwork.org)