Bone marrow and blood stem cell transplantation. Medical search. Frequent questions

high-risk patients included male subjects, recipients of stem cells from female donors, patients younger than 10 years, those with nonidentical donors, and those who received radiation therapy in the transplant preparative regimen. (medscape.com)
In a study from the United States, long-term survivors of pediatric bone marrow transplantation followed in the Bone Marrow Transplant Survivors Study were compared with survivors of childhood cancer treated without bone marrow transplant from the Childhood Cancer Survivor Study. (medscape.com)
Your child had a bone marrow transplant. (medlineplus.gov)
Tell your child's dentist that your child has had a bone marrow transplant. (medlineplus.gov)
Gassas A , Grant R , Richardson S , Dupuis LL , Doyle J , Allen U , Predictors of viridans streptococcal shock syndrome in bacteremic children with cancer and stem-cell transplant recipients. (cdc.gov)
For people who have weakened immune systems, especially people who have had an organ, stem cell or bone marrow transplant, CMV infection can be fatal. (mayoclinic.org)
People who have weakened immune systems, such as those who have had an organ, bone marrow or stem cell transplant, or those who are infected with HIV. (mayoclinic.org)
A stem cell transplant is when cells are taken out of the blood for use in a transplant. (differencebetween.net)
A bone marrow transplant is when stem cells are removed from the bone marrow for transplant. (differencebetween.net)
What is Stem Cell Transplant? (differencebetween.net)
This is when stem cells that are obtained from the bloodstream or umbilical cord of a donor are used for transplant into a patient. (differencebetween.net)
Umbilical cord blood stem cells are only used for transplant into children since there are not enough cells present to be of any use for transplant into an adult patient. (differencebetween.net)
Stem cell transplant can be used to treat conditions such as multiple myeloma, and other cancers such as certain kinds of lymphoma and leukemia. (differencebetween.net)
A bone marrow transplant is when stem cells are removed from a donor's bone marrow for transplant into a patient. (differencebetween.net)
A stem cell transplant is when stem cells are harvested from the bloodstream or the umbilical cord. (differencebetween.net)
A bone marrow transplant is when stem cells are harvested directly from the bone marrow. (differencebetween.net)
In the case of a stem cell transplant, granulocyte- colony-stimulating factor has to be given to the donor a few days before the procedure. (differencebetween.net)
Historical transplants used a matched donor's peripheral blood or bone marrow to transplant to a patient. (biologynews.net)
Zweidler-McKay also predicts this type of transplant could be used for adults who have already had a transplant or for those adult and pediatric patients who aren't candidates for other stem cell transplants due to blood counts or illness. (biologynews.net)
Bone marrow/stem cell transplantation , including traditional and reduced-intensity transplant, using related, unrelated or umbilical cord blood cells for transplant. (dana-farber.org)
Late-occurring Venous Thromboembolism in Allogeneic Blood or Marrow Transplant Survivors - a BMTSS-HiGHS2 Risk Model. (stembook.org)
Transplant Cell Ther. (stembook.org)
Follistatin and Soluble Endoglin Predict 1-year Non-Relapse Mortality after Allogeneic Hematopoietic Cell Transplant. (stembook.org)
Biol Blood Marrow Transplant. (stembook.org)
Retrospective analysis by the Center for International Blood and Marrow Transplant Research (CIBMTR): Prompt complete remission plus consolidation therapy yields improved survival after allogeneic hematopoietic cell transplantation (allo-HCT) for patients with acute myeloid leukemia (AML) receiving a myeloablative conditioning regimen and not a reduced-intensity conditioning regimen. (ascopost.com)
GVHD is a common problem after a transplant using donor cells. (bmtinfonet.org)
Some patients may benefit from a bone marrow transplant. (rxwiki.com)
and translational and basic science researchers from the Pediatric Acute Lung Injury and Sepsis Investigators Network, the EBMT, the Pediatric Blood and Marrow Transplant Consortia, and several other institutions with extensive experience in sinusoidal obstructive syndrome. (uni-regensburg.de)
Methods Center for International Blood and Marrow Transplant Research data from 184 adults who completed the Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) before undergoing alloHCT and at day 100 were used. (cdc.gov)
Regret was measured using a FACT-BMT item not included in scoring: "I regret having the bone marrow transplant. (cdc.gov)
This type of transplantation, also known as a bone marrow transplant, is one of the common treatments used to treat several blood malignancies. (lu.se)
If it weren't for the hematopoietic stem cells, this transplant would only be a transient therapy meaning its effects would only last a short time. (lu.se)
Australasian Trends in Allogeneic Stem Cell Transplantation for Myelofibrosis in the Molecular Era: A retrospective analysis from The Australasian Bone Marrow Transplant Recipient Registry. (cdc.gov)
Hopefully, following the recommendations made in the guidelines will reduce morbidity and mortality from opportunistic infections in hematopoietic stem cell transplant recipients. (cdc.gov)
For the purposes of this document, HSCT is defined of the CDC, the Infectious Diseases Society of America, as any transplantation of blood or marrow-derived he- and the American Society of Blood and Marrow Trans- matopoietic stem cells, regardless of transplant type plantation," which was published in the Morbidity and (allogeneic or autologous) or cell source (bone marrow, Mortality Weekly Report [1]. (cdc.gov)

For example, in developing and developed countries alike, kidney transplantation not only yields survival rates and quality-of-life that are far superior to those obtained with other treatments for end-stage renal disease, such as haemodialysis, but is also less costly in the long run. (who.int)
The aim of the academic journal is to provide a platform for researchers, scientists, physicians, and other health professionals to find latest research information in the areas of stem cell research, transplantations such as stem cell transplantation, transplantation immunology, kidney transplantation and its treatment. (slideshare.net)
A 20-year-old female patient underwent kidney transplantation for renal failure. (bvsalud.org)

Multivariable analysis revealed that creatinine ≥2 mg/dl, extramedullary disease, ≤very good partial remission and non-autologous hematopoietic stem cell transplantation are independent risk factors for shorter survival. (scielo.br)
Estimate the failure-free survival rate in a cohort of relapsed Hodgkin's lymphoma and non-Hodgkin's lymphoma patients after retrieval therapy which includes peripheral blood stem cell transplantation (PBSCT) in patients who achieve a complete remission or partial remission. (knowcancer.com)
LOS ANGELES (AP) - Selma Blair says she's in remission from multiple sclerosis as a result of undergoing stem cell transplantation. (turnto23.com)
People in remission from AML may be candidates for allogeneic stem cell transplantation. (clevelandclinic.org)
6. Malignancies, including a history thereof, with the exception of cured basal cell carcinoma, cervical cancer in situ, as well as cured solid tumors with a remission of more than 5 years. (who.int)

1 This includes human cells for transplantation such as haematopoietic stem cells from bone marrow, peripheral blood or cord blood. (who.int)
Patients can be cured with bone marrow transplantations of haematopoietic stem cells. (lu.se)

p = 0.001) and higher in those who received autologous hematopoietic stem cell transplantation. (scielo.br)
Although multiple myeloma patients younger than 66 years of age have an aggressive presentation, this did not translate into an inferior overall survival, particularly in those undergoing autologous hematopoietic stem cell transplantation. (scielo.br)
Autologous hematopoietic stem cell transplantation, or aHSCT for short, is usually used to treat blood cancers, and involves harvesting stem cells from the person's own bone marrow or blood followed by chemotherapy and antibody treatment. (news-medical.net)
Peripheral blood has largely replaced bone marrow as a source of stem cells, especially in autologous hematopoietic stem cell transplantation, because stem cell harvest is easier and neutrophil and platelet counts recover faster. (msdmanuals.com)
There are no contraindications to autologous hematopoietic stem cell transplantation. (msdmanuals.com)

She specializes in pediatric hematology and has particular expertise in the care of children undergoing stem cell transplantation for noncancerous disorders, such as sickle cell anemia, aplastic anemia and thalassemia. (choa.org)
Choice of conditioning regimens for bone marrow transplantation in severe aplastic anemia. (stembook.org)
The first patient was received an allogeneic bone marrow transplantation and subsequent allogeneic peripheral blood stem cell transplantation for severe aplastic anemia from his sister. (koreamed.org)
Healthcare providers may recommend allogeneic stem cell transplantation for severe forms of aplastic anemia. (clevelandclinic.org)
Hematopoietic stem cell transplantation (bone marrow, cord blood, or peripheral blood stem cells) may cure aplastic anemia and prevent myelodysplastic syndrome or leukemia. (medscape.com)

Patients who undergo bone marrow transplantation are generally immunosuppressed with a dose of cyclophosphamide which is usually calculated based on the patient's weight. (slideshare.net)
Patients who undergo bone marrow transplantation frequently have hemorrhagic cystitis because most are exposed to cyclophosphamide, total-body irradiation, or both. (medscape.com)

Successful stem cell transplantation for patients with severe combined immunodeficiency (SCID) from matched family donors without conditioning results in engraftment of T lymphocytes. (nih.gov)
These substances include, for instance, granulocyte- colony-stimulating factor (G-CSF), which is added so that the donors own bone marrow will make and produce more stem cells that will end up in the bloodstream. (differencebetween.net)
Organ Transplantation.2 These Guiding Principles - whose emphases include voluntary donation, noncommercialization, genetic relation of recipients to donors and a preference for cadavers over living donors as sources - have considerably influenced professional codes, national, state and provincial legislation, and the policies of intergovernmental organizations. (who.int)
Peripheral Blood versus Bone Marrow from Unrelated Donors: Bone Marrow allografts have improved Long-term Overall and Graft-versus-Host Disease, Relapse-Free Survival. (stembook.org)
Infections following Transplantation of Bone Marrow or Peripheral-Blood Stem Cells from Unrelated Donors. (stembook.org)
Neither vitiligo nor evidences of autoimmune diseases were found in their stem cell donors. (koreamed.org)
Allogeneic hematopoietic stem cell transplantation is limited mainly by lack of histocompatible donors. (msdmanuals.com)
Exclusion of prospective blood donors based on their acknowledged risk behaviors for human immunodeficiency virus (HIV) infection began in 1983 (1). (cdc.gov)
In 1985, when tests for HIV antibody became available, screening prospective donors of blood, organs, and other tissues also began (2,3). (cdc.gov)

Validation of prognostic factors and survival of patients with multiple myeloma in a real-life autologous stem cell transplantation setting: a Swiss single centre experience. (smw.ch)
Bone marrow transplants are also used in cases where a person has cancers such as some types of lymphomas and leukemias, and multiple myeloma. (differencebetween.net)
Multiple myeloma (MM) is a plasma cell malignancy in which monoclonal plasma cells proliferate in bone marrow, resulting in an overabundance of monoclonal paraprotein (M protein), destruction of bone, and displacement of other hematopoietic cell lines. (medscape.com)
Bone marrow aspirate demonstrating plasma cells of multiple myeloma. (medscape.com)
Reduction in late mortality among patients with Multiple Myeloma treated with Autologous Peripheral Blood Stem Cell Transplantation - a BMTSS Report. (stembook.org)

Other treatment options for patients with enzyme or protein deficiencies include substrate reduction therapy, gene therapy, and bone-marrow derived stem cell transplantation. (wikipedia.org)
The place of high-dose BEAM therapy and autologous bone marrow transplantation in poor-risk Hodgkin's disease. (smw.ch)
High-dose therapy and autologous bone marrow transplantation after failure of conventional chemotherapy in adults with intermediate-grade or high-grade non-Hodgkin's lymphoma. (smw.ch)
The role of intensive therapy and autologous blood and marrow transplantation for chemotherapy-sensitive relapsed and primary refractory non-Hodgkin's lymphoma: identification of major prognostic groups. (smw.ch)
Patients undergoing fludarabine therapy (purine analog) , bone marrow transplantation or peripheral blood stem cell transplantation. (utmb.edu)
Researchers from The University of Texas M. D. Anderson Cancer Center have found a therapy that effectively kills human leukemia cells in mice using natural killer (NK) cells from umbilical cord blood. (biologynews.net)
However, Zweidler-McKay and co-senior investigator Elizabeth Shpall, M.D., professor in M. D. Anderson's Department of Stem Cell Transplantation and Cellular Therapy, have found a novel process to increase NK cells in cord blood more than 30-fold, generating more than 150 million NK cells from one cord blood unit while maintaining their activation to find and kill acute leukemia cells. (biologynews.net)
[ 2 ] Options for second-line therapy in patients with relapsed/refractory disease include chemotherapy-free regimens with biologic targeted agents such as covalent Bruton tyrosine kinase (BTK) inhibitors, lenalidomide,venetoclax, and chimeric antigen receptor (CAR) T-cell therapy. (medscape.com)
Large doses of chemotherapy and/or radiation therapy are then applied to kill the cancer cells. (epnet.com)
Recombinant human lysosomal acid lipase is an 'enzyme replacement therapy' that is expected to work by replacing the missing enzyme in lysosomal acid lipase deficiency, helping to break down fats and stopping them building up in the body's cells. (europa.eu)
This was the first example of a successful SC therapy, and is still commonly used today for blood and bone-marrow-related cancers such as leukemia and myeloma. (parentsguidecordblood.org)
One area where cell therapy has generated hope is neurology. (parentsguidecordblood.org)
Cell therapy protocols for cerebral palsy are an example of a new approach to a condition that is difficult to treat. (parentsguidecordblood.org)
It is because of these stem cells and their capacity to regenerate and rebuild the entire hematopoietic (blood) system that makes transplantation a promising therapy. (lu.se)
At post transplantation day plus 3, antibiotic drug therapy was switched from piperacillin/tazobactam to meropenem. (cdc.gov)

OUTLINE: Patients receive 2 courses of reinduction chemotherapy followed by bone marrow biopsy and aspirate prior to peripheral blood stem cell (PBSC) harvest. (knowcancer.com)
A bone marrow biopsy will be performed to allow your doctor to look for marrow abnormalities, such evidence of pre-cancerous or cancerous cells. (childrenshospital.org)
A biopsy of an enlarged lymph node or bone marrow will be taken and examined to figure out the specific type of cancer based on several tissue biological markers as well as cell structure. (rxwiki.com)

Create healthcare diagrams like this example called Leukemia - Stem Cell Transplantation in minutes with SmartDraw. (smartdraw.com)
The killing of leukemia cells is proportional to the radiation absorbed dose. (nature.com)
Patients with monoclonal gammopathy of unknown significance, smoldering MM, plasma cell leukemia and amyloidosis were excluded. (scielo.br)
[ 1 ] First described in 1848, MM is part of a spectrum of diseases ranging from monoclonal gammopathy of unknown significance ( MGUS ) to plasma cell leukemia. (medscape.com)
Patrick Zweidler-McKay, M.D., Ph.D., assistant professor of pediatrics from the Children's Cancer Hospital at M. D. Anderson, has shown an effective method for expanding the number of NK cells from a single cord blood unit while retaining the cells' anti-leukemia effects, as presented at the American Society of Pediatric Hematology/Oncology annual conference on May 16. (biologynews.net)
When given to mice with aggressive human leukemias, these NK cells reduced the circulating human acute lymphocytic leukemia (ALL) and acute myelogenous leukemia (AML) cells by 60 to 85 percent. (biologynews.net)
These NK cells demonstrate significant cytotoxic activity against human AML and ALL cell lines and patient leukemia blasts. (biologynews.net)
T-prolymphocytic leukemia (T-PLL) is an aggressive mature T-cell neoplasm that responds poorly to conventional chemotherapy and has a dismal outcome. (haematologica.org)
1 T-PLL cells commonly demonstrate rearrangements involving T-cell leukemia/lymphoma 1 (TCL1) family genes TCL1A, MTCP1 (mature T-cell proliferation), or TCL1B as molecular hallmarks. (haematologica.org)
The second patient underwent allogeneic bone marrow transplantation for acute myelogeneous leukemia from his sister. (koreamed.org)
Leukemia is an umbrella term for cancers affecting the blood-forming cells in the body. (medicalnewstoday.com)
Acute myelogenous leukemia (AML) is a type of cancer that involves the bone marrow. (medicalnewstoday.com)
It is different than other forms of leukemia because it has eight distinct subtypes, which develop from different types of cells. (medicalnewstoday.com)
AML is the most common type of acute leukemia in adults, and it happens when the bone marrow begins making myeloblasts, also called blasts. (medicalnewstoday.com)
Doctors use this treatment regimen to eliminate leukemia cells and bring blood counts back to normal. (medicalnewstoday.com)
Consolidation chemotherapy can follow induction chemotherapy to treat any remaining leukemia cells that are not visible in the blood or bone marrow. (medicalnewstoday.com)
AML (Acute Myeloid Leukemia) is a blood cancer (haematological malignancy), and the standard way of treating older AML patients is chemotherapy. (lu.se)

Anna's scientific curiosity has led her to explore the regenerative dynamics of hematopoietic stem cells, also known as blood stem cells. (lu.se)
My focus has been on hematopoietic stem cells and how they respond to different kinds of stress. (lu.se)
Hematopoietic stem cells are the stem cells that give rise to all other blood cells in the body. (lu.se)
This new marker can be used to specifically identify functionally potent hematopoietic stem cells during the regenerative process. (lu.se)
Opportunistic infections (OIs) are defined as any in- the infusion of hematopoietic stem cells from a donor fections that occur with increased frequency or severity into a patient who has received chemotherapy, which in HSCT patients. (cdc.gov)

OBJECTIVE: To assess the prognostic value of various parameters including positron emission tomography / computed tomography (PET/CT) and identify risk factors for survival of patients with non-Hodgkin's lymphoma (NHL) and Hodgkin's lymphoma (HL) treated with autologous stem cell transplantation (ASCT). (smw.ch)
Of the NHL patients, 59 (44%) had diffuse large B-cell lymphoma (DLBCL). (smw.ch)
Other risk factors for survival were primary refractory disease, initial lymphoma stage, number of previous chemotherapy lines, and high amounts of blood product transfusions. (smw.ch)
Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin's lymphoma. (smw.ch)
High-dose sequential chemotherapy followed by autologous stem cell transplantation in relapsed and refractory aggressive non-Hodgkin's lymphoma: results of a multicenter phase II study. (smw.ch)
High dose sequential chemotherapy and autologous stem cell transplantation in patients with relapsed/refractory lymphoma. (smw.ch)
Cancer Care provides free, professional support services for people affected by cutaneous T-cell lymphoma, as well as cutaneous T-cell lymphoma treatment information and additional resources. (cancercare.org)
Oncology social workers help you cope with the emotional and practical challenges of cutaneous t-cell lymphoma. (cancercare.org)
Mantle cell lymphoma (MCL) is a lymphoproliferative disorder derived from a subset of naive pregerminal center cells localized in primary follicles or in the mantle region of secondary follicles. (medscape.com)
Mantle cell lymphoma (MCL) is recognized in the Revised European-American Lymphoma and World Health Organization classifications as a distinct clinicopathologic entity. (medscape.com)
it was frequently categorized as diffuse small-cleaved cell lymphoma (by the International Working Formulation) or centrocytic lymphoma (by the Kiel classification). (medscape.com)
Although use of stem cell treatments in medicine is still in its early stages, they are currently being used to treat people with blood and immune system conditions, such as leukaemia and lymphoma. (centenary.org.au)
Hodgkin lymphoma is distinguished from other diseases classified as lymphoma primarily because of the presence of Reed-Sternberg cells, which are large, cancerous cells found in Hodgkin lymphoma tissues. (rxwiki.com)

Distinctive patterns of genes turned off -- or left on -- in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them scientists say. (sciencedaily.com)
DNA methylation inhibitors already are under study at MCG and other centers for a variety of cancers and blood disorders. (sciencedaily.com)
Because tumor cells that result from aberrant changes shed their DNA into bodily fluids, non-invasive screening for a wide range of cancers could result be another result of this initiative, Dr. Bhalla says. (sciencedaily.com)
Dr. Robertson, who also works in breast cancer and brain tumors as well as colon cancer, is finding patterns of genes that regulate healthy cell differentiation are shut off in cancers. (sciencedaily.com)
Older adults with cancers of the blood often have different needs from younger adults, for example, a higher risk for heart disease, diabetes, or kidney problems, which may limit treatment options. (dana-farber.org)
In general, cancers result from mutations in cells. (medicalnewstoday.com)
Allogeneic stem cell transplantation uses donor stem cells to treat and sometimes cure certain blood disorders and blood cancers. (clevelandclinic.org)
What cancers are treated with allogeneic stem cell transplantation? (clevelandclinic.org)
Not all cancers or blood diseases respond to stem cell transplantation, including allogeneic stem cell transplantation. (clevelandclinic.org)

Peripheral blood stem cell and bone marrow transplantation for solid tumors and lymphomas: hematologic recovery and costs. (nature.com)
Hematopoietic stem cell transplantation is also sometimes used for solid tumors (eg, some germ cell tumors) that respond to chemotherapy. (msdmanuals.com)

The donor first has to be treated with G-CSF, and then the stem cells can only be harvested a couple of days after the donor since time is needed for the donor's body to form more stem cells and transport these cells into the bloodstream. (differencebetween.net)
Healthcare providers identify HLA with blood tests comparing your HLA with your prospective donor's HLA. (clevelandclinic.org)
Before apheresis, the donor's blood count showed mild thrombocytopenia after G-CSF mobilization. (cdc.gov)

Bone Marrow Transplantation (2000) 26, 877-880. (nature.com)
Bone Marrow Transplantation (2000) 25, 807-813. (nature.com)
Globally, it is estimated that 120 000 corneal transplantations and 18 000 transplantations of allogeneic haematopoietic progenitor cells took place in the year 2000. (who.int)

People who have undergone stem cell or organ transplants seem to be at greatest risk. (mayoclinic.org)
Stem cell transplants involve cells that are taken out of the blood or umbilical cord. (differencebetween.net)
Bone marrow transplants involve cells that are taken out of the bone marrow. (differencebetween.net)
Graft-versus-host disease is a common side effect of patients receiving stem cell transplants, which results when the T cells in the transplanted blood react against the patient's own cells. (biologynews.net)
The number of human tissue transplants is increasing in both developed and developing countries, but global data on this form of transplantation are less complete. (who.int)
Access to transplantation is limited in low- and many medium-income countries, where the rate of transplants remains far below that of richer nations. (who.int)
Cord blood and haploidentical (half-matched) transplants are used to treat an increasing number of patients. (bmtinfonet.org)

Stem cell transplantation is performed after high-dose chemotherapy (HDC) to restore a cancer patient's blood and immune cell production capacity. (bdbiosciences.com)
Successful transplantation of organs and living tissues depends on continued medical follow-up and the patient's compliance with a regimen of immunosuppressive drugs. (who.int)
Starting back in the 1950s, blood-forming SCs were first used to repopulate a patient's immune system. (parentsguidecordblood.org)
The patients enrolled in our trial received a subcutaneous medication for 4 consecutive days to stimulate their bone marrow to produce SCs, their bone marrow was then harvested, SCs were concentrated at the laboratory, and then they were delivered through the patient's cerebrospinal fluid on the fifth day of the procedure. (parentsguidecordblood.org)
Hematopoietic stem cell transplantation may be autologous (using the patient's own cells) or allogeneic (using cells from a donor). (msdmanuals.com)
Because of the patient's risk status, the physicians intended to perform allogeneic stem cell transplantation after induction and consolidation chemotherapy, which was scheduled to end in January 2013, and a conditioning chemotherapy regimen, which was planned to be given in March. (cdc.gov)

Characterize the time to recovery of normal bone marrow function after transplantation in these patients. (knowcancer.com)

The Flow Cytometry Laboratory provides flow cytometric analysis of blood, bone marrow and other tissues. (hamiltonhealthsciences.ca)
Nonetheless, the transplantation of organs and tissues does raise ethical concerns. (who.int)
In dyskeratosis congenita and other telomere diseases, the protective caps on people's chromosomes shorten too quickly, causing cells and tissues to age prematurely. (childrenshospital.org)
In the absence of this enzyme, called lysosomal acid lipase, fats accumulate in the body's cells and tissues, causing symptoms such as growth failure, enlarged liver, diarrhoea and malabsorption (when nutrients from food are not easily absorbed during digestion). (europa.eu)
They create cells that range from muscle cells to brain cells and they can, in some cases, fix damaged tissues. (centenary.org.au)
Stem cells can develop into any type of cell in the body, making them valuable for repairing damaged tissues and organs. (centenary.org.au)
The adult cells are found in small numbers in most tissues, such as bone marrow or fat. (centenary.org.au)
Although previous recommendations for preventing transmission of human immunodeficiency virus (HIV) through transplantation of human tissue and organs have markedly reduced the risk for this type of transmission, a case of HIV transmission from a screened, antibody-negative donor to several recipients raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
A working group formed by the Public Health Service (PHS) in 1991 to address these issues concluded that further recommendations should be made to reduce the already low risk of HIV transmission by transplantation of organs and tissues. (cdc.gov)
This occurrence raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
The working group concluded that, although existing recommendations are largely sufficient, revisions should be made to reduce the already low risk of HIV transmission via transplantation of organs and tissues. (cdc.gov)

http://www.researchandmarkets.com/research/f7thqr/organ_and_tissue ) has announced the addition of the "Organ and Tissue Transplantation - Global Strategic Business Report" report to their offering. (prnewswire.com)
This report analyzes the worldwide markets for Organ and Tissue Transplantation in Number of Procedures. (prnewswire.com)
The global and regional markets (except the US) for 'Organ and Tissue Transplantation' in this report are analyzed by the following Product Segments - Organ Tranplantation (Heart, Kidneys, Liver, Pancreas, and Lungs). (prnewswire.com)

Similarly, corneal transplantation can successfully relieve corneal blindness in many cases. (who.int)

Flow cytometric enumeration of CD34+ HSCs and progenitor cells is an established method for the evaluation of bone marrow and stem cell grafts. (bdbiosciences.com)
eg, bone, bone marrow, and skin grafts) Genetically identical (syngeneic [between monozygotic twins]) donor tissue (isografts) Genetically. (msdmanuals.com)

Likewise, many children are now surviving hematopoietic stem-cell transplantation (HSCT) (see related histology slide below) and require structured long-term follow-up care. (medscape.com)
30,000 patients with blood-related malignancies receive HDC, which, if the response is satisfactory, could subsequently be followed by hematopoietic stem cell transplantation (HSCT). (bdbiosciences.com)
Sinusoidal obstructive syndrome, also known as hepatic veno-occlusive disease, is a potentially life-threatening complication that occurs in children undergoing haemopoietic stem-cell transplantation (HSCT). (uni-regensburg.de)
The Hematopoietic stem cell transplantation (HSCT) is used in children as a definitive treatment for various oncological, immune deficiencies, hemoglobinopathy, and malignancies diseases that involve the hematological system, congenital metabolism disorders, among others. (bvsalud.org)
This is a quantitative, retrospective, observational, descriptive and analytical quantitative approach approaching the medical records of children and adolescents submitted to HSCT in a referral hospital service for this type of transplantation in the state of Rio Grande do Sul North (RN). (bvsalud.org)
The allogeneic HSCT was the most frequently performed (57.14%) and the most used source of Hematopoietic progenitor cells (HPC) was the peripheral blood (54.29%) and 5.71% of these patients developed the Graft versus Host Disease (GVHD), of which one was affected by acute GVHD and another by chronic GVHD. (bvsalud.org)
The profile of the clinical variables presented by the children and adolescents of this study shows that the most prevalent diagnosis was ALL, the most frequent toxicities were gastrointestinal, cardiac, respiratory and hematological, the most common HSCT was allogeneic peripheral blood and the greatest cause of mortality was sepsis. (bvsalud.org)
Hematopoietic stem cell transplantation not responded to other therapeutic modalities, with (HSCT) is used in children as a definitive treatment an increase in survival after transplantation, for different oncological, immune deficiencies, contributing to its use (YEILIPEK, 2014). (bvsalud.org)
are basically 3 phases of immune recovery for HSCT patients, The purposes of the guidelines are (1) to summarize the beginning at day 0, the day of transplantation. (cdc.gov)

Low-dose filgrastim significantly enhances neutrophil recovery following autologous peripheral-blood stem-cell transplantation in patients with lymphoproliferative disorders: evidence for clinical and economic benefit. (smw.ch)
Hematology (from the Greek word 'haima', meaning blood) is the branch of internal medicine that deals with the physiology, pathology, etiology, diagnosis, treatment, prognosis and prevention of blood-related disorders. (apollohospitals.com)
Dr. Arnold is a Pediatric Hematologist/Oncologist at the Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Associate Professor of Pediatrics at Emory University School of Medicine. (choa.org)
This is a group of rare disorders caused by mutations in different genes involved in the development and function of infection-fighting immune cells. (clevelandclinic.org)
Allogeneic stem cell transplantation may cure some blood disorders FA causes. (clevelandclinic.org)
Healthcare providers consider several factors before recommending allogeneic stem cell transplantation to treat blood disorders or cancer. (clevelandclinic.org)

Fanconi anemia is the most frequently reported of the rare inherited bone marrow failure syndromes (IBMFSs). (medscape.com)
Pathophysiology of inherited bone marrow failure syndromes. (medscape.com)

These immature stem cells were easier to match to patients, especially those from non-Caucasian ethnicities, and could be stored for use as needed. (biologynews.net)
Because cord blood contains immature stem cells, HLA matching appears less crucial than for the other types of hematopoietic stem cell transplantation. (msdmanuals.com)

They can affect multiple parts of the the lymphoid tissue, including the lymph nodes, spleen, and the bone marrow and are further classified into fast-growing or slow-growing. (rxwiki.com)

Previous efforts to expand cord blood have resulted in ineffective NK cells. (biologynews.net)
Cord blood is a promising source of natural killer cells because the NK cells have enhanced sensitivity to stimulation, decreased potential to cause graft-versus-host disease and are available from cord banks throughout the country and world," says Zweidler-McKay. (biologynews.net)
However, in 1988, researchers found cord blood to be another source for stem cell transplantation. (biologynews.net)
Zweidler-McKay's study involves selecting out NK cells from cord blood. (biologynews.net)
As the cord blood is expanded to multiply in number, the NK cells are given a cytokine, interleukin-2, and a target cell, K562, which keep the NK cells active throughout the three week expansion. (biologynews.net)
These results support the evaluation of cord blood-derived NK cells as a potential immuno-therapeutic approach in acute leukemias. (biologynews.net)
She underwent hematopoietic stem cell transplantation which uses stem cells derived from bone marrow, peripheral blood, or umbilical cord blood. (turnto23.com)
An overview of bone marrow, peripheral blood stem cell and cord blood transplantation. (bmtinfonet.org)
These treatments use stem cells from umbilical cord blood or bone marrow or haematopoietic stem cell transplantation. (centenary.org.au)
The positive result came too late to save cord blood. (sunjournal.com)
A transplantation of stem cells, from umbilical cord blood or from a peripheral stem cell or bone marrow donor, is appropriate for some boys with the disease, such as those with early symptoms and MRI abnormalities. (sunjournal.com)
The current US clinical trials, listed in ClinicalTrials.gov , are dependent upon the fact that parents chose to preserve their child's umbilical cord blood at the time of birth. (parentsguidecordblood.org)
Our clinical trial, listed as ClinicalTrials.gov NCT01019733 , was carried out at a University Hospital in Monterrey, Mexico, where we treated children with cerebral palsy that were not able to bank their cord blood. (parentsguidecordblood.org)
In the meantime, we believe that patients with cerebral palsy can be treated with their own bone marrow SCs when their cord blood SCs were not preserved. (parentsguidecordblood.org)
There she started the cryopreservation laboratory and the first public cord blood bank in Mexico. (parentsguidecordblood.org)
These stem cells may come from a family member, from someone you don't know or from umbilical cord blood. (clevelandclinic.org)
Umbilical cord blood is blood collected from the umbilical cord and placenta after a baby is born. (clevelandclinic.org)
Umbilical cord hematopoietic stem cell transplantation has been restricted mainly to children because there are too few stem cells in umbilical cord blood for an adult. (msdmanuals.com)
One concern about the procedure is that immune cells in cord blood do not have experience with the viruses responsible for latent infections, leading to a higher percentage of naive T cells and thus increased vulnerability to reactivation of cytomegalovirus or Epstein-Barr virus infection. (msdmanuals.com)
For umbilical cord blood harvest, the cord is clamped after delivery of the baby, and blood is drawn from the cord with a needle and collected in a sterile bag. (msdmanuals.com)
peripheral blood, or placental/umbilical cord blood). (cdc.gov)

however, nearly all cases eventually relapse, and allogeneic stem cell transplantation remains the only curative treatment option for a small subset of patients. (haematologica.org)
Research suggests that while treatments such as intensive chemotherapy and allogeneic stem cell transplantation may be curative for younger people, they are less likely to be effective in older individuals. (medicalnewstoday.com)
Background: Allogeneic hematopoietic stem cell transplantation (alloHCT) is potentially curative but with known negative effects on quality of life. (cdc.gov)

In contrast to the expected mixed chimerism that usually occurs in the absence of conditioning, we found in our patients 100% donor cell engraftment based on fluorescence in situ hybridization (FISH) and microsatellite techniques. (nih.gov)
National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines also recommend the use of serum free light chain assay and plasma cell fluorescence in situ hybridization (FISH) on bone marrow: del 13, del 17p13, t(4;14), t(11;14), t(14;16), t(14;20), 1q21 amplification, 1p deletion as part of the initial diagnostic workup. (medscape.com)

In order to assess the incidence and analyze reasons which cause prolongation of hospital stay in patients engrafted after peripheral blood stem cell transplantation (PBSCT), we performed this retrospective analysis. (nature.com)

For many hematopoietic malignancies, collection and infusion of CD34+ hematopoietic stem/progenitor cells following chemotherapy is critical. (bdbiosciences.com)
The Malignant Hematology Laboratory's primary focus is the diagnosis of hematologic malignancies from blood and bone marrow samples, utilizing microscopy and special stains. (hamiltonhealthsciences.ca)
Hematopoietic stem cell transplantation has become a major treatment option for patients with hematopoietic malignancies and immune deficiencies. (cdc.gov)

Blood Adv. 2022. (stembook.org)

Access to transplantation entails more than the surgery itself, because success is measured by longer survival of the patient and a long-term improvement in the quality of life. (who.int)

Red blood cells do not provide viable platelets, nor do they provide clinically significant amounts of coagulation factors. (utmb.edu)
Further benefits are that the platelets and neutrophil cells (one of the white blood cells) are more easily able to recover if this method is used compared with the bone marrow procedure. (differencebetween.net)
Individuals with DC typically have an abnormally low number of red blood cells, white cells, or platelets. (childrenshospital.org)

Blood Adv. 2020;4(12):2810-2820. (stembook.org)

Other recommendations include treatment of infections with antibacterials, antifungals, and antivirals, intravenous gamma-globulin infusion, irradiation of all blood products. (lu.se)

The technique for umbilical cord hematopoietic stem cell transplantation is still in its infancy, but it is gaining interest. (msdmanuals.com)

It will take 6 to 12 months or more for your child's blood counts and immune system to fully recover. (medlineplus.gov)
Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
A lot of people think of cancer cells turning genes on, like oncogenes, that allow them to grow faster, evade immune surveillance, that sort of thing," Dr. Robertson says. (sciencedaily.com)
In an attempt to control infection, masses of neutrophils and other immune cells continue to gather at the site of infection, forming large groups of these cells called granulomas, hence the name of the disease. (primaryimmune.org)

In addition to complications seen from exposure to chemotherapy and radiation, patients undergoing allogeneic transplantation can experience unique late effects secondary to graft versus host disease (GVHD) and autoimmunity. (medscape.com)
If your child received bone marrow from someone else, look for signs of graft-versus-host disease ( GVHD ). (medlineplus.gov)

2 Evaluation of harvest adequacy requires the use of reliable progenitor cell assays and this is usually achieved by CD34 cell counting using flow cytometry. (bdbiosciences.com)
Flow cytometric applications for CD34+ cell identification and enumeration provide a rapid, quantitative and reproducible method to evaluate the progenitor cell population. (bdbiosciences.com)

These diseases can often cause bone marrow failure and lung disease. (childrenshospital.org)
Stem cell research is important because it has the potential to both better understand and furthermore, cure diseases and injuries that currently have no effective treatments. (centenary.org.au)
This makes them beneficial for researchers wanting to learn about various human cells and diseases in the laboratory. (centenary.org.au)
The research community is also actively engaged in expanding our understanding of stem cells and their potential applications in overcoming various diseases. (centenary.org.au)
Non-Hodgkin lymphomas (NHL) represent a varied group of diseases distinguished by the features of the cancerous cells with each disease type. (rxwiki.com)
Many of these specialists also treat the diseases that stem from these addictions. (vitals.com)

The procedure can also be used to replace bone marrow which has been somewhat depleted because of some types of cancer treatments. (differencebetween.net)
It can also be used to help patients whose own bone marrow has been destroyed because of cancer treatments. (differencebetween.net)
Additionally, many new treatments called monoclonal antibodies have been successfully used ( rituximab ( Rituxan ) for B-cell lymphomas, ofatumumab (Arzerra) for NHL, Ocrelizumab is in clinical trials). (rxwiki.com)
Healthcare providers typically recommend stem cell transplantation if initial treatments don't work or if conditions have come back. (clevelandclinic.org)
Providers may recommend allogeneic stem cell transplantation if initial treatments didn't work or treatments worked but the condition has come back. (clevelandclinic.org)
While both treatments help your bone marrow to develop new blood cells, studies show allogeneic stem cell transplantations work by causing the donor cells to attack unhealthy cells. (clevelandclinic.org)
Providers may use allogeneic stem cell transplantation if other treatments aren't successful. (clevelandclinic.org)
Some medical treatments may affect transplantation. (clevelandclinic.org)

An induced pluripotent stem cell (iPSC), is an adult stem cell which has been altered in a lab to behave more like embryonic stem cells. (centenary.org.au)
Nevertheless, the use of autologous bone marrow-derived SCs does not face ethical, political, biological and regulatory hurdles, like embryonic stem cells does. (parentsguidecordblood.org)

NK cells operate differently from T cells, leaving normal cells alone while targeting and killing the cancerous cells. (biologynews.net)

Chronic granulomatous disease (CGD) is a type of primary immunodeficiency (PI) in which one group of the body's white blood cells, called neutrophils, fail to make the hydrogen peroxide, bleach, and other chemicals needed to fight bacterial and fungal infections. (primaryimmune.org)
Allogeneic stem cell transplantation treats the recurring and life-threatening infections this condition causes. (clevelandclinic.org)
Hemorrhagic cystitis results from damage to the bladder's transitional epithelium and blood vessels by toxins, viruses, radiation, drugs (in particular, chemotherapeutic drugs), bacterial infections, or other disease processes. (medscape.com)
This article contains highlights of "Guidelines for Pre- allogeneic or autologous, depending on the source of venting Opportunistic Infections among Hematopoi- the transplanted hematopoietic progenitor cells. (cdc.gov)

High-dose chemotherapy with autologous bone marrow transplantation: 11 years' experience in Zurich. (smw.ch)

Non-Hodgkin lymphomas can stem from B cells or T cells. (rxwiki.com)

Anatomy33

Organisms10

Diseases53

Chemicals and Drugs46

Analytical, Diagnostic and Therapeutic Techniques and Equipment77

Psychiatry and Psychology2

Phenomena and Processes35

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena2

Information Science4

Named Groups5

Health Care15

Transplant35

Kidney Transplantation3

Remission5

Haematopoietic stem cells2

Autologous hematopoietic stem cell trans5

Aplastic anemia5

Undergo bone marrow transpla2

Donors9

Multiple myeloma5

Therapy15

Biopsy3

Leukemia17

Hematopoietic stem5

Lymphoma13

Cancers9

Solid tumors2

Donor's3

20003

Transplants7

Patient's6

Normal bone marrow1

Tissues11

Organ and Tissue Transplantation3

Corneal Transplantation1

Grafts2

HSCT9

Disorders6

Failure syndromes2

Immature stem cells2

Lymphoid1

Cord blood21

Curative3

Fluorescence in situ hybri2

PBSCT1

Malignancies3

20221

Survival1

Platelets3

20201

Irradiation1

Umbilical cord1

Immune4

GVHD2

Progenitor cell2

Diseases6

Treatments8

Embryonic stem2

Cancerous cells1

Infections4

High-dose chemotherapy1

Lymphomas1