Loading...
  • vivo
  • To figure out if IL-6 is a element implicated in the ex vivo bone marrow amplification noticed in the existence of PTH and Flt-3L, bone marrow cells had been cultured for 8 times with a single remedy of PTH, Flt-3L or PTH plus Flt-3L in the existence and absence of IL-6 at the time of plating. (c14-demethylase.com)
  • solid
  • Frequently, a trephine biopsy is also obtained, which yields a narrow, cylindrically shaped solid piece of bone marrow, 2mm wide and 2 cm long (80 μL), which is examined microscopically (sometimes with the aid of immunohistochemistry) for cellularity and infiltrative processes. (wikipedia.org)
  • The needle is then advanced with a twisting motion and rotated to obtain a solid piece of bone marrow. (wikipedia.org)
  • human bone marrow
  • The chapter examines pathologic findings seen in the human bone marrow. (springer.com)
  • In-vitro colony forming cell (CFC) assays using normal human bone marrow grown in appropriate semi-solid media such as ColonyGEL have been shown to be useful in predicting the level of clinical myelotoxicity a certain compound might cause if administered to humans. (wikipedia.org)
  • progenitor
  • These predictive in-vitro assays reveal effects the administered compounds have on the bone marrow progenitor cells that produce the various mature cells in the blood and can be used to test the effects of single drugs or the effects of drugs administered in combination with others. (wikipedia.org)
  • produces
  • The marrow produces RBCs at a rate that replaces old RBCs that age and degrade or are lost through bleeding, striving to maintain a relatively constant number of RBCs in the blood. (labtestsonline.org)
  • donation
  • If you're not sure about joining the register, then just spend some time finding out more about bone marrow and the donation process. (warwick.ac.uk)
  • That same year, Katharina's father Peter founded DKMS (which is the German acronym for "bone marrow donation center) in honor of his wife. (forbes.com)
  • thrombocytes
  • Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes). (wikipedia.org)
  • tibia
  • In some restaurants, cooked pig tibia would be served with a drinking straw specifically for sucking out the semi-liquified marrow. (wikipedia.org)
  • disorders
  • Diagnosis of lymphoid disorders that involve the marrow are discussed. (springer.com)
  • Bone marrow failure syndromes are relatively rare and universally complex disorders. (childrens.com)
  • The Bone Marrow Failure Program at the Gill Center has the breadth and depth of expertise needed to provide complete care to children and their families affected by these hematologic disorders. (childrens.com)
  • chemotherapy
  • Bone marrow is suppressed with the use of cancer chemotherapy. (news-medical.net)
  • Bone marrow suppression due to anti-cancer chemotherapy is much harder to treat and often involves hospital admission, strict infection control, and aggressive use of intravenous antibiotics at the first sign of infection. (wikipedia.org)
  • aplastic
  • A leading contributor to bone marrow failure disorder registries, including the International Fanconi Anemia Registry, Diamond-Blackfan Registry, Shwachman- Diamond Registry and North American Pediatric Aplastic Anemia Consortium (NAPAAC). (childrens.com)
  • donors
  • At the time, there were only 3,000 bone marrow donors registered in Germany. (forbes.com)
  • Bone marrow donors have to be in good physical health and be between 18 and 55 years old. (forbes.com)
  • To facilitate the exchange of information and improve business relations, the WMDA provides access to contact data of organisations that are listing donors or cord blood products in the global database of Bone Marrow Donors Worldwide. (wikipedia.org)
  • patients
  • In immunocompromised patients, B19 infection may persist for months, leading to chronic anemia with B19 viremia due to chronic marrow suppression. (wikipedia.org)
  • needle
  • An aspirate needle is inserted through the skin using manual pressure and force until it abuts the bone. (wikipedia.org)
  • Then, with a twisting motion of clinician's hand and wrist, the needle is advanced through the bony cortex (the hard outer layer of the bone) and into the marrow cavity. (wikipedia.org)
  • Once the needle is in the marrow cavity, a syringe is attached and used to aspirate ("suck out") liquid bone marrow. (wikipedia.org)
  • The needle is then advanced with a twisting motion and rotated to obtain a solid piece of bone marrow. (wikipedia.org)
  • A needle is used to withdraw samples of the marrow from within the bone. (news-medical.net)
  • syndromes
  • We rely on a comprehensive panel of subspecialists with an express interest in bone marrow failure syndromes. (childrens.com)
  • We counsel families on the underlying genetic causes of bone marrow failure syndromes, and offer them carrier testing when appropriate. (childrens.com)
  • abnormal
  • A fatigue fracture is caused by the prolonged cyclical application of abnormal mechanical stresses to a bone that has normal elastic resistance. (amazonaws.com)