Bone and tissues. Medical search. Frequent questions

Bone marrow adipose tissue (BMAT), sometimes referred to as marrow adipose tissue (MAT), is a type of fat deposit in bone marrow. (wikipedia.org)
Since BMAT is increased in the setting of obesity and is suppressed by endurance exercise, or vibration, it is likely that BMAT physiology, in the setting of mechanical input/exercise, approximates that of white adipose tissue (WAT). (wikipedia.org)
Visceral abdominal fat (VAT) is a distinct type of WAT that is "proportionally associated with negative metabolic and cardiovascular morbidity", regenerates cortisol, and recently has been tied to decreased bone formation Both types of WAT substantially differ from brown adipose tissue (BAT) as by a group of proteins that help BAT's thermogenic role. (wikipedia.org)
The team's target was stem cells derived from human fat, or human adipose (hASC) cells and the process these stem cells use to convert to bone cells when stimulated to do so. (futurity.org)
This is the first study to use ECIS to predict and monitor the potential of adipose cells transforming into bone cells," Loboa says. (futurity.org)
Bone marrow adipose tissue (MAT) contributes to increased circulating adiponectin, an insulin-sensitizing hormone, during caloric restriction (CR), but whether this occurs in other contexts remains unknown. (frontiersin.org)
The antidiabetic thiazolidinediones (TZDs) also promote MAT expansion and hyperadiponectinemia, even without increasing adiponectin expression in white adipose tissue (WAT). (frontiersin.org)
Finally, rosiglitazone upregulated uncoupling protein 1 in brown adipose tissue (BAT), but this protein was undetectable in tibiae, suggesting that MAT is unlikely to share thermogenic properties of BAT. (frontiersin.org)
Adipose tissue is typically classified into two broad subtypes, white adipose tissue (WAT) and brown adipose tissue (BAT). (frontiersin.org)
In addition to WAT and BAT, adipocytes also exist in the bone marrow, and such marrow adipose tissue (MAT) has been estimated to account for over 10% of total adipose tissue mass in lean, healthy humans ( 3 ). (frontiersin.org)
Most adipocytes exist in discrete depots throughout the body, notably in well-defined white and brown adipose tissues. (wustl.edu)
Whereas bone marrow adipose tissue (BMAT) shares many properties in common with white adipose tissue, the distinct functions of BMAT are reflected by its development, regulation, protein secretion, and lipid composition. (wustl.edu)
The adipose tissue is an important reservoir of adult stem cells which have capacity of differentiating in osteoblasts with potential implication in reaching bone regeneration. (bvsalud.org)
To evaluate the immunoexpression of BMP-2 protein on the bone repairing of critical size defects (CSD) surgically created in rat calvaria and treated by autogenous macerated adipose tissue. (bvsalud.org)
The animals were randomly divided into two groups: group C (control) and group AT (macerated adipose tissue grafting). (bvsalud.org)
In group AT, the defect was filled with autogenous macerated adipose tissue. (bvsalud.org)
In group AT, both at 7 and 90 post-operative days, the main healing type was the presence of dense conjunctive tissue exhibiting bundles of collagen fibers disposed in beams permeating the remaining adipose tissue with rare heterotopic bone formation associated to fibrosis and different types of tissue necrosis. (bvsalud.org)
Within the limits of this present study, it can be concluded that the adipose tissue grafting did not favor bone neoformation in critical size defects and BMP-2 signaling was not observed. (bvsalud.org)

The initial study is a proof-of-concept to see if printed structures can mimic the gradual transition from smooth, compressible cartilage to hard bone at the end of long bones. (innovationtoronto.com)
Bioscientists are moving closer to 3D-printed artificial tissues to help heal bone and cartilage typically damaged in sports-related injuries to knees, ankles and elbows. (innovationtoronto.com)
Scientists at Rice University and the University of Maryland reported their first success at engineering scaffolds that replicate the physical characteristics of osteochondral tissue - basically, hard bone beneath a compressible layer of cartilage that appears as the smooth surface on the ends of long bones. (innovationtoronto.com)
The gradient nature of cartilage-into-bone and its porosity have made it difficult to reproduce in the lab, but Rice scientists led by bioengineer Antonios Mikos and graduate student Sean Bittner have used 3D printing to fabricate what they believe will eventually be a suitable material for implantation. (innovationtoronto.com)
The key is mimicking tissue that turns gradually from cartilage (chondral tissue) at the surface to bone (osteo) underneath. (innovationtoronto.com)
The Biomaterials Lab at Rice printed a scaffold with custom mixtures of a polymer for the former and a ceramic for the latter with imbedded pores that would allow the patient's own cells and blood vessels to infiltrate the implant, eventually allowing it to become part of the natural bone and cartilage. (innovationtoronto.com)
The future of the project will involve figuring out how to print an osteochondral implant that perfectly fits the patient and allows the porous implant to grow into and knit with the bone and cartilage. (innovationtoronto.com)
In the short term, 3D printing is more likely to prove useful when replacing broken cartilage and bone. (alphr.com)
Christopher's Original Formulas Complete Tissue and Bone (formerly Bone Flesh & Cartilage) is a synergistic combination of 12 whole food herbs. (taoofherbs.com)
For example, what if in your cheek skin a piece of cartilage forms and attaches to the underlying cheek bone? (ipscell.com)
Hutmacher, D. W. Scaffolds in tissue engineering bone and cartilage. (nature.com)
A synergistic combination of herbs that helps support bones, flesh & cartilage. (simplygenesis.com)
Cartilage is a smooth, rubbery tissue that protects the joints and allows for smooth movement of the bones. (arthritiscure.me)
This is because it is one of the richest plant sources of silica, a mineral that is important for the growth and maintenance of bones, cartilage, and other connective tissues. (arthritiscure.me)
Progress in microsphere-based scaffolds in bone/cartilage tissue engineering. (bvsalud.org)
Bone / cartilage repair and regeneration have been popular and difficult issues in medical research . (bvsalud.org)
In recent years, microsphere -based scaffolds have been considered suitable scaffold materials for bone / cartilage injury repair because microporous structures can form more internal space for better cell proliferation and other cellular activities, and these composite scaffolds can provide physical/chemical signals for neotissue formation with higher efficiency . (bvsalud.org)
We found that PLF was present primarily in the cellular periosteum, articular cartilage, osteoblasts, osteocytes and osteoclasts at weeks 3 and 6 in all distal bone sites examined. (cdc.gov)

Beim Indo-German Workshop "Design and manufacturing of biomaterials and implants for dental and cranio-maxillofacial reconstruction and bone regeneration (BIODENT)", der vom 13. (tu-dresden.de)
Particularly for bone defect regeneration, the complex coupling of biological mechanisms to the scaffolds' properties has led to a widespread trial-and-error approach. (kit.edu)
Here, we consider two complementary approaches: first, an efficient macroscopic optimization routine based on a simple one-dimensional time-dependent model for bone regeneration in the presence of a bioresorbable polymer scaffold is developed. (kit.edu)
The result of the optimization procedure is a scaffold porosity distribution which maximizes the stiffness of the scaffold and regenerated bone system over the regeneration time, so that the propensity for mechanical failure is minimized. (kit.edu)
A growing ageing population with an increased risk of bone fractures due to falls1, regrettably often combined with impaired bone healing and even higher fracture risk due to osteoporosis2 and diabetes3,4, and, in addition, to the currently inevitable loosening of prosthetic implants over time5, urgently requires adequate bone regeneration strategies. (bioskinrevive.com)
For all those Dinaciclib reasons above, it becomes obvious that systems without the requirement of cell isolation and propagation would increase the chances to meet the need of the increasing quantity of individuals for bone regeneration. (bioskinrevive.com)
When the hydrogels were used to transplant MSCs, the hydrogel's elasticity regulated bone regeneration, with optimal bone formation at 60 kPa. (nature.com)
Figure 4: Matrix elasticity regulates MSC-mediated bone regeneration. (nature.com)
One of these advancements is guided bone regeneration, also referred to as guided tissue regeneration. (lakesuccessperio.com)
To address these pockets, Dr. Shreck may recommend tissue regeneration. (lakesuccessperio.com)
Dr. Shreck will help you determine if bone regeneration surgery is right for you. (lakesuccessperio.com)
Recently, carbon-modified biomaterials for bone tissue engineering have been extensively investigated to potentially revolutionize biomaterials for bone regeneration. (openorthopaedicsjournal.com)
This review summarizes the chemical and biophysical properties of carbon nanostructures and discusses their functionality in bone tissue regeneration. (openorthopaedicsjournal.com)
In the quest for alternative therapeutic strategies, research is focusing on the concept of tissue engineering to assist the progress of bone tissue regeneration. (openorthopaedicsjournal.com)
Questions about Guided Bone or Tissue Regeneration ? (periocarecarolinas.com)
To address these pockets the doctors at Advanced Oral Surgery & Periodontics may recommend tissue regeneration. (advancedoralsurgerymn.com)
bone regeneration. (bvsalud.org)

The aim of this project is to develop RGD modified alginate bioinks for creating 3D-printed scaffolds for bone tissue engineering. (upc.edu)

Although previous recommendations for preventing transmission of human immunodeficiency virus (HIV) through transplantation of human tissue and organs have markedly reduced the risk for this type of transmission, a case of HIV transmission from a screened, antibody-negative donor to several recipients raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
A working group formed by the Public Health Service (PHS) in 1991 to address these issues concluded that further recommendations should be made to reduce the already low risk of HIV transmission by transplantation of organs and tissues. (cdc.gov)
This occurrence raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
The working group concluded that, although existing recommendations are largely sufficient, revisions should be made to reduce the already low risk of HIV transmission via transplantation of organs and tissues. (cdc.gov)
Transplantation of Organs and Tissues of Human Origin, adopted by the Council of Europe in 2002. (who.int)

In this context, tissue engineering becomes relevant for the treatment of large bone defects, where cells or growth factors are incorporated into a three-dimensional scaffold to mimic native tissue architecture and function in terms of osteoconduction, osteoinduction and osteointegration. (amrita.edu)
An innovative biomimetic apatite hierarchically structured in parallel fastened hollow microtubules has been synthesized, structurally characterized and proposed as a new inorganic biomorphic scaffold providing a biomimetic nanostructure surface for fascinating bone engineering applications. (rsc.org)
A lot of the implants we are developing, we can implant into a patient and as the tissue grows back, it is not rejected, the scaffold will reabsorb over time and the tissue will grow even more and eventually the implant is gone," says QUT associate professor Mia Woodruff. (alphr.com)
Due to their large surface area and ability to interact with proteins and peptides, graphene oxides offer valuable physiochemical and biological features for biomedical applications and have been successfully employed for optimizing scaffold architectures for a wide range of organs, from the skin to cardiac tissue. (mdpi.com)
Tissue engineering is rapidly evolving to provide new solutions to this problem, and the key point is to design the appropriate scaffold biomaterial . (bvsalud.org)

Isolating RNA from tissues and paraffin-embedded tissue samples can be challenging due to cross-linking of biomolecules and fragmented nucleic acids. (labettor.com)
Isolating DNA from tissues and paraffin-embedded tissue samples can be challenging as double-stranded DNA is physically fragile and highly susceptible to exo- and endonucleases. (labettor.com)
For early pregnancy loss/miscarriage, please send POCs fixed in formalin (wet tissues, not formalin-fixed paraffin-embedded tissue blocks), if possible. (cdc.gov)

Segmental bone defects resulting from trauma or pathological conditions represent formidable clinical challenges in orthopaedic surgery. (amrita.edu)
The aim of the present investigation was to evaluate the healing of bone defects (fresh extraction sockets) after implant installation with flap elevation, and primary closure compared with implant installation without flap elevation. (allenpress.com)
This study use histologic and histomorphometric analyses to evaluate tissue healing around dental implants with marginal bone defects with and without flap elevation 1 week, 4 weeks, and 12 weeks after implantation in the dogs. (allenpress.com)
Preclinical studies, showing that implantation of excess fat or muscle tissue fragments transduced with an adenoviral BMP-2 vector induces structural and practical healing of large segmental bone defects, were recently reported20,21,22,23. (bioskinrevive.com)
It is also important to consult plastic surgeons when skin grafts, local flaps, or free tissue flaps are needed for final coverage of defects. (medscape.com)
The need for artificial bone graft material, particularly for large defects which cannot be filled with autologous bone, is driving research into synthetic alternatives1,2. (bath.ac.uk)
Recent advances in developing biocompatible materials for treating bone loss or defects have dramatically changed clinicians' reconstructive armory. (openorthopaedicsjournal.com)

Hematopoietic cells (also known as blood cells) reside in the bone marrow along with BMAds. (wikipedia.org)
These hematopoietic cells are derived from hematopoietic stem cells (HSC) which give rise to diverse cells: cells of the blood, immune system, as well as cells that break down bone (osteoclasts). (wikipedia.org)
In this paper we present a strategy of combining next generation RNA-sequencing with in situ affinity-based proteomics in order to identify and describe new gene targets for further research on lymphatic or hematopoietic cells and tissues. (nih.gov)
Herein we review the site specificity, age-related development, regulation and metabolic characteristics of BMAT under various metabolic conditions, including the functional interactions with bone and hematopoietic cells. (wustl.edu)

Development of an angiogenesis-promoting microvesicle-alginate-polycaprolactone composite graft for bone tissue engineering applications. (stembook.org)
Thus, with the aim to characterize the TME of CI-deficient tumors in a model that more faithfully represents osteosarcoma development, we set up a humanized bone niche ectopic graft. (crick.ac.uk)
However, it remained unclear, whether the BMP-2 transduced cells graft itself can undergo transdifferentiation into bone or if the graft rather serves as a delivery system for growth factors which stimulate and attract stem cells of the surrounding cells21. (bioskinrevive.com)
2003. Bone Graft Substitutes: ASTM International 2Stevens MM. 2008. (bath.ac.uk)
We studied 5 consecutive cases of GCT involving the distal radius operated by en-bloc resection of tumor followed by reconstruction with ipsilateral non-vascularized fibular graft with a minimum 1 year follow-up. (jbstjournal.com)

The Human Protein Atlas project aims to systematically map the human gene and protein expression landscape in a multitude of normal healthy tissues as well as cancers, enabling the characterization of both housekeeping genes and genes that display a tissue-specific expression pattern. (nih.gov)
This article focuses on identifying and describing genes with an elevated expression in four lymphohematopoietic tissue types (bone marrow, lymph node, spleen and appendix), based on the Human Protein Atlas-strategy that combines high throughput transcriptomics with affinity-based proteomics. (nih.gov)
The results constitute lists of genes with enriched or enhanced expression in the four lymphohematopoietic tissues, exemplified also on protein level with immunohistochemical images. (nih.gov)
Tissue total protein is prepared from whole tissue homogenates. (biochain.com)
Bone morphogenetic protein (BMPs) are referred to as bone tissue forming growth elements. (bioskinrevive.com)
This review critically focuses on opportunities to employ protein-graphene oxide structures either as nanocomposites or as biocomplexes and highlights the effects of carbonaceous nanostructures on protein conformation and structural stability for applications in tissue engineering and regenerative medicine. (mdpi.com)
Silica helps the body produce collagen, a protein that provides the structural framework for bones. (arthritiscure.me)
The evaluation of the osteoblastic differentiation can be verified through immunohistochemical markers such as bone morphogenetic protein- 2 (BMP-2). (bvsalud.org)
METHODS: We have analysed short- and long-read RNA sequencing data from breast tumours, breast cancer cell lines, and normal tissues to create a comprehensive annotation of ER transcripts and combined it with experimental studies of full-length protein and six alternative isoforms. (lu.se)

The pseudo-orthotopic approach allowed investigation of osteosarcoma progression in a bone-like microenvironment setting, without being invasive as the intrabone cell transplantation. (crick.ac.uk)

Thus, bone fragility, osteoporosis, and osteoporotic fractures are thought to be linked to mechanisms which promote BMAT accumulation. (wikipedia.org)
The results of the biomechanical study show that femurs of rats treated by Pb-acetate appeared to be weaker than bones of the control group, and may produce a condition for the development of higher risk of fractures. (aaem.pl)
Studies have suggested that silica supplements may help improve bone mineral density and reduce the risk of fractures. (arthritiscure.me)
However, not all osteoporotic individuals suffer atraumatic fractures, and the association between bone mass and fracture incidence has yet to be clearly defined. (cdc.gov)
The osteoporosis component will also include assessment of risk factors for low bone mass and for falling, since both are related to the occurrence of osteoporotic hip fractures. (cdc.gov)

No consensus currently exists regarding the use of percutaneous needle biopsy for diagnosis of soft tissue and bone tumors in children, Cooke-Barber and colleagues explained. (auntminnie.com)
With the advent of next-generation sequencing and gene-targeted chemotherapy protocols, there is an ever-increasing need for tissue samples to facilitate the histopathological and biochemical evaluation of tumors that allows for the use of targeted treatment protocols," they wrote. (auntminnie.com)
BATON ROUGE, LA (WAFB) - Mary Bird Perkins - Our Lady of the Lake Cancer Center announced today the opening of a new clinic focused exclusively on treating patients with tumors of the soft tissue, muscles, and bones. (wafb.com)
A prominent involvement of TME was revealed in CI-deficient tumors, characterized by the abundance of cancer associated fibroblasts, tumor associated macrophages and preservation of osteocytes and osteoblasts in the mineralized bone matrix. (crick.ac.uk)
Giant cell tumors (GCT) of the bone are aggressive and are recognised for variable clinical behaviour, which is not always related to radiographic or histological appearance [1]. (jbstjournal.com)

Bone marrow adipocytes (BMAds) originate from mesenchymal stem cell (MSC) progenitors that also give rise to osteoblasts, among other cell types. (wikipedia.org)
However, adipocytes also reside within specialized niches, of which the most abundant is within bone marrow. (wustl.edu)

Derubeis, A.R. and Cancedda, R. (2004) Bone marrow stromal cells (BMSCs) in bone engineering: Limitations and recent advances. (scirp.org)
The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells. (nature.com)

During aging, bone quantity declines and fat redistributes from subcutaneous to ectopic sites such as bone marrow, muscle, and liver. (wikipedia.org)
The needle itself may provide drainage and a release of pressure, and it may also mechanically disrupt the scar tissue in the muscle. (medscape.com)
Objectives: To explore the total and regional muscle-to-bone ratio in children and adolescents with obesity and compare the muscle-to-bone ratio (MBR) and soft tissue-to-bone ratio (SBR) to their peers with normal weight or overweight. (umn.edu)

Soft Tissue and Bone Tumours is the third volume in the 5th edition of the WHO series on the classification of human tumours. (who.int)
This volume will be of particular interest to pathologists, oncologists, surgeons, and epidemiologists who manage or research soft tissue and bone tumours. (who.int)
METHODS: We have analysed short- and long-read RNA sequencing data from breast tumours, breast cancer cell lines, and normal tissues to create a. (lu.se)

It is concluded that laminin is useful for bone formation, as in an in vitro culture study using bone marrow cells, in hydroxyapatite scaffolds in vivo . (scirp.org)

Biomaterials for bone tissue engineering. (bath.ac.uk)
A wide range of synthetic and natural biomaterials is being used to develop tissue-engineered bone. (openorthopaedicsjournal.com)
Incorporation of carbon nanostructures significantly improves the mechanical properties of various biomaterials to mimic that of natural bone. (openorthopaedicsjournal.com)

abstract = "Although preliminary results have been achieved on many different fronts in applying BMSSC technology to tissue engineering, a tremendous amount of work still confronts researchers in this area. (sahmri.org.au)

Complete Tissue & Bone 4 oz. (simplygenesis.com)

But now modern-day science has validated the horsetail myth by proving that horsetail is useful in strengthening connective tissue. (arthritiscure.me)
It has even been said that taking inorganic calcium in your diet is dangerous, and can lead to calcium deposits inside joints and connective tissue. (arthritiscure.me)

The best solution is to slice the tissues into smaller pieces and make a homogenate solution (using tissue homogenizer or grinding liquid nitrogen frozen samples) in presence of RNAse inhibitors. (labettor.com)

Standard bone tissue engineering approaches require isolation and propagation of autologous cells, followed by seeding about a variety of scaffolds. (bioskinrevive.com)
Whilst it is clear that BMSSC-mediated osteogenesis has the capacity to integrate with pre-existing bone tissue, substantial progress in this and other approaches needs to be achieved for the accurate reassembly of functional complex organ systems. (sahmri.org.au)

Could bactrim be effective for possible joint or bone infection? (healthtap.com)
Does a failed dental implant due to bone loss always mean there's infection? (healthtap.com)
Without infection symptoms what else can cause a bone scan to light up? (healthtap.com)
A description of soft-tissue infection includes simple, moderate, and severe infection, which includes but is not limited to infections in the immunocompromised patient, infections associated with PVD, emergency soft-tissue infections, and infections associated with trauma. (medscape.com)
Diabetics tend to develop ulcerations in the feet, which often lead to infection of the soft tissue and bones. (medscape.com)
Guidelines for the management of complicated skin and soft-tissue infections have been published by the Surgical Infection Society (SIS). (medscape.com)
This ulceration could be probed to bone, and a deep space infection was present. (medscape.com)

4 The resulting bone loss that ensues is mainly in the horizontal aspect, but some loss also occurs in the vertical dimension. (allenpress.com)

Additive manufacturing (AM) is a rapidly emerging technology that has the potential to produce personalized scaffolds for tissue engineering applications with unprecedented control of structural and func- tional design. (kit.edu)

If they just make a bit of subcutaneous fat then in theory they could "smooth out" wrinkles, but what if these MSCs decide for whatever reason they will become an undesired tissue type in your face? (ipscell.com)

The procedure was part of an early-stage clinical trial of a revolutionary tissue-engineering technology developed by Bonus BioGroup of Haifa. (cufi.org)
In December 2016, Bonus BioGroup announced successful results of an early-stage clinical trial on 11 patients in which bone tissue grown from a small sample of each patient's own fat cells was injected into their jaws to repair bone loss. (cufi.org)
Mikos said the collaboration is a great early success for the Center for Engineering Complex Tissues (CECT), a National Institutes of Health center at Maryland, Rice and the Wake Forest School of Medicine developing bioprinting tools to address basic scientific questions and translate new knowledge into clinical practice. (innovationtoronto.com)
The "biofabrication" institute in Herston Health Precinct , Brisbane, will be a space where doctors are able to develop techniques to engineer new tissue using advanced clinical scanning, modeling and 3D printing. (alphr.com)
Diagnosis and management of Paget's disease of bone in adults: a clinical guideline. (msdmanuals.com)
Paget's disease of bone: an Endocrine Society clinical practice guideline. (msdmanuals.com)
Bone mass can decrease without symptoms for a significant period of time before fracture occurs, and since fracture is the main clinical sign of the disease, many clinicians and researchers limit the definitions of osteoporosis to the presence of an atraumatic fracture. (cdc.gov)

Although more research is needed to confirm these effects, it is thought that silica may increase the production of osteoblasts (bone-building cells) and reduce the activity of osteoclasts (cells that break down bone tissue). (arthritiscure.me)

Huang, G.T., Gronthos, S. and Shi, S. (2009) Mesenchymal stem cells derived from dental tissues vs. those from other sources: Their biology and role in regenerative medicine. (scirp.org)

It increases in states of low bone density -osteoporosis, anorexia nervosa/ caloric restriction, skeletal unweighting such as that which occurs in space travel, and anti-diabetes therapies. (wikipedia.org)

Scientists can now watch how human fat cells transform into bone tissue cells. (futurity.org)
however, there is still a lot to learn about how stem cells grow and convert to needed tissues," says Elizabeth Loboa, dean of the University of Missouri's College of Engineering. (futurity.org)
therefore, our team decided to analyze and study a new approach to monitoring stem cells as they transform into tissues we may need to treat disease. (futurity.org)
Using human fat-derived stem cells from young (aged 24-36 years), middle-aged (aged 48-55 years), and elderly (aged 60-81) participants, the team used ECIS to collect complex measurements during the growth and differentiation stages the hASC exhibited as they converted to bone cells. (futurity.org)
The effect of laminin on hard tissue formation using rat bone marrow cells was assessed. (scirp.org)
Rat bone marrow cells were obtained from femora of 6-week-old male Fischer 344 rats. (scirp.org)
Rat bone marrow cells in 200 m l culture medium at 1 × 10 6 cells/ml were seeded in the scaffolds. (scirp.org)
For i n vitro examinations, 1 × 10 5 rat bone marrow cells in 2 ml culture medium were then cultured with the addition of dexamethasone and laminin. (scirp.org)
Rat bone marrow cells were also cultured in laminin-coated culture plates. (scirp.org)
From the in vivo examination, laminin coating of the scaffolds induced hard tissue in the pores with the cells. (scirp.org)
Yoshikawa, M. , Kakigi, H. , Yabuuchi, T. and Hayashi, H. (2014) Effects of laminin on hard tissue formation by bone marrow cells in vivo and in vitro . (scirp.org)
Medical history was made at Emek Medical Center in Afula this week when semi-liquid live human bone tissue grown in a lab from a 40-year-old patient's own fat cells was transplanted into the patient's arm by injection. (cufi.org)
Dinaciclib Therefore, the aim of the present study was to investigate whether human excess fat cells comprising inhomogeneous cell populations is definitely capable of transdifferentiation into cells with bone characteristics. (bioskinrevive.com)
Furthermore, BMP-9 appears to be a more powerful osteogenic inducer for cells within fats tissues than BMP-2 or -7. (bioskinrevive.com)
Other stem cells can also produce non-desired tissue growth. (ipscell.com)
INTRODUCTION: The aim of this project was to perform CFD analysis of liquid-solid fluidisation to inform the design and development of a fluidised bed bioreactor for the culture and growth of bone cells seeded into porous bioceramic particles. (bath.ac.uk)
These findings demonstrate the application of CFD modelling to enable the successful design and development of a fluidised bed bioreactor for the culture and growth of bone cells seeded on to porous bioceramic particles. (bath.ac.uk)
Release of damaged cells and tissue debris occurs upon injury. (medscape.com)
Demineralization assays, utilizing weak acids to isolate organics from biomineralized tissues, have recently been applied with increasing frequency to explore soft tissue preservation in fossils, revealing frequent retention of cells and other pliable microstructures in fossil bones. (lu.se)
PCB methyl sulphones and related compounds: Identification of target cells and tissues in different species. (cdc.gov)

and manufactures products to restore tissue and organ function. (innovationtoronto.com)
A 1991 investigation determined that several recipients had been infected with HIV by an organ/tissue donor who had tested negative for HIV antibody at the time of donation (4). (cdc.gov)

Imaging -- particularly CT -- is an effective tool for guiding percutaneous soft tissue and bone mass biopsies in children, according to a study published January 19 in the Annals of Surgical Oncology . (auntminnie.com)
Our study found that] image-guided percutaneous biopsy is a safe and effective method of obtaining accurate tissue samples in children and young adults with soft tissue or bone masses," the group noted. (auntminnie.com)
This is especially true for pediatric patients with soft tissue and bone masses. (auntminnie.com)
Among the disorders treated at the Musculoskeletal Oncology Clinic are soft tissue, bony, and retroperitoneal sarcomas - a rare group of cancers that originate in the bones and/or in the connective tissues of the body. (wafb.com)
Combining their unique skills, Drs. Accardo and Lyons head the team of physicians and allied health professionals in a mission to combat sarcoma and other diseases of the bones and soft tissue. (wafb.com)
There are more than 80 different subtypes of soft tissue sarcoma or sarcoma-like growths," said Dr. Accardo, orthopedic surgeon and musculoskeletal oncologist at the Cancer Center. (wafb.com)
The technique of immediate implant placement after extraction has been conceived for preserving residual bone support and soft tissue morphology. (allenpress.com)
Under the experimental conditions of this study, no biological differences were observed between the 2 groups with and without flap elevation in terms of crestal bone repair, inflammation, marginal bone loss, and soft tissue downgrowth. (allenpress.com)
The situation is definitely exacerbated by a rising quantity of devastating traumatic war accidental injuries for which Dinaciclib often no additional treatment option than amputation is present due to the extensive loss of bone and soft cells6. (bioskinrevive.com)
Many events can be responsible for these soft-tissue infections. (medscape.com)
Given the limited soft-tissue envelope, it is common for bone to be involved when an infectious process is present in the foot. (medscape.com)
Sections are included on all recognized neoplasms of the soft tissue and bone, as well as on genetic tumour syndromes affecting these sites. (who.int)
During this surgical procedure, the pockets are cleaned thoroughly, and a membrane is installed between the soft tissue and the pocket in the bone. (lakesuccessperio.com)
The membrane covers the pocket so that fast-growing soft tissue is blocked, and slower-growing bone can begin to grow, or "regenerate" itself. (lakesuccessperio.com)
The SBR was determined by dividing the soft tissue mass (i.e., lean mass+fat mass) by bone mineral content. (umn.edu)
They are categorized into 3 groups: soft tissue, bone, and diabetic foot infections. (medscape.com)
It is predisposed to this because of the close proximity to the skin and lack of a thick, soft tissue, protective layer throughout most parts of the foot. (medscape.com)
Although these findings hint at possible controls on cellular and soft tissue preservation in fossil bones, they should be viewed cautiously as they are demonstrably biased by uneven sampling. (lu.se)
Schweitzer, Mary H. / A STATISTICAL META-ANALYSIS OF LITHOLOGIC AND OTHER POTENTIAL CONTROLS ON FOSSIL BONE CELLULAR AND SOFT TISSUE PRESERVATION . (lu.se)

The bones most commonly affected are the pelvis, femur, and skull. (msdmanuals.com)

BMAT is thought to result from preferential MSC differentiation into an adipocyte, rather than osteoblast lineage in osteoporosis based on the inverse relationship between bone and BMAT in bone-fragile osteoporotic states. (wikipedia.org)
The decision to include assessments of bone density in the survey was based on the recognition of the growing problem of osteoporosis, or decreased bone mass. (cdc.gov)
The low bone mass that characterizes osteoporosis causes an increased susceptibility to spontaneous or a traumatic bone fracture. (cdc.gov)
Estimates of low bone density derived from NHANES III data will offer unique information regarding bone loss and osteoporosis. (cdc.gov)

The goal of treatment of this tumor at the distal radius is complete removal of the tumor and reconstruction of the bone defect in order to preserve maximum function of the wrist joint. (jbstjournal.com)

collagen fibers lack a parallel arrangement, have many different orientations, often arranged in bundles distributed in all directions throughout the tissue ex. (flashcardmachine.com)

Journal of Bone and Mineral Research, 14, 561-568. (scirp.org)
The lower bone mineral content and the weaker mechanical properties of bones from Pb-treated rats are associated with the pathologic state dependent of the exposure of lead. (aaem.pl)
Palaniappan PL. RM, Krishnakumar N, Vadivelu M, Vijayasundaram V. The study of the changes in the biochemical and mineral contents of bones of Catla. (aaem.pl)
The MBR was calculated by dividing lean mass by bone mineral content. (umn.edu)
NHANES III will provide the first reference data on bone density from a nationally representative sample and will permit an examination of bone mineral density in black and Hispanic population subgroups, for whom prevalence of low bone mass is poorly defined. (cdc.gov)

Several studies demonstrated exercise reduction of BMAT which occurs along with an increase in bone quantity. (wikipedia.org)
Since exercise increases bone quantity, reduces BMAT and increases expression of markers of fatty acid oxidation in bone, BMAT is thought to be providing needed fuel for exercise-induced bone formation or anabolism. (wikipedia.org)
A notable exception occurs in the setting of caloric restriction: exercise suppression of BMAT does not yield an increase in bone formation and even appears to cause bone loss. (wikipedia.org)
BMAT, by its "specific marrow location, and its adipocyte origin from at least LepR+ marrow MSC is separated from non-bone fat storage by larger expression of bone transcription factors", and likely indicates a different fat phenotype. (wikipedia.org)
BMAT increases in states of bone fragility. (wikipedia.org)
Antiresorptive therapies like risedronate or zoledronate also decrease BMAT while increasing bone density, supporting an inverse relationship between bone quantity and BMAT. (wikipedia.org)

Silica deficiency almost always precedes calcium loss and can result in the demineralization of bone. (arthritiscure.me)
To address this, we compiled a database of bone demineralization results from 29 studies, then conducted a statistical meta-analysis of these data to evaluate the importance of specimen age, taxonomy, entombing lithology, and bone tissue type on microstructure recovery. (lu.se)

Dr. Wu investigated and determined that injected MSCs for the face-lift had grown bone in the skin next to her eye , bone that grew onto existing tissue and could blinded this woman in that eye. (ipscell.com)
If you're looking to re-mineralize bones, support connective tissues, build healthy skin, improve the condition of your nails, and thicken your hair, this proven herbal arthritis supplement could be just what you're looking for. (arthritiscure.me)

Wake Forest Baptist Medical Centre in the US, however, recently developed a method for 3D printing tissue that allowed blood vessels and nerves to grow into the implants. (alphr.com)
What if the MSCs sprout a mass of blood vessels or bone in your face? (ipscell.com)
Analytical methods have been developed to measure benzene levels in exhaled breath, blood, and various body tissues. (cdc.gov)
Gunshot wounds that pass through the body without hitting major organs, blood vessels, or bone tend to cause less damage. (medlineplus.gov)
Osteocytes, blood vessels, and fibrous/proteinaceous matrix each exhibit bimodal recovery patterns in which most fossil bones either yield many or none of these microstructures. (lu.se)
In 1985, when tests for HIV antibody became available, screening prospective donors of blood, organs, and other tissues also began (2,3). (cdc.gov)
Obtain a better view of organs, blood vessels, tissues and bones. (cdc.gov)

The resulting infiltration of tissues by the leukocytes, plasma proteins, and fluid causes the redness, swelling, and pain that are characteristic of inflammation. (medscape.com)

In trauma and orthopaedic surgery, extended bone loss is associated with considerable technical and physiological issues. (openorthopaedicsjournal.com)

The field of tissue engineering is constantly evolving as it aims to develop bioengineered and functional tissues and organs for repair or replacement. (mdpi.com)

Anatomy68

Organisms10

Diseases42

Chemicals and Drugs55

Analytical, Diagnostic and Therapeutic Techniques and Equipment49

Psychiatry and Psychology1

Phenomena and Processes35

Disciplines and Occupations1

Technology, Industry, Agriculture8

Health Care5

Adipose18

Cartilage18

Regeneration17

Scaffolds for bone tissue1

Organs and tissues5

Scaffold5

Paraffin-embedded tissue3

Defects7

Hematopoietic cells4

Graft5

Protein9

Transplantation1

Fractures5

Tumors5

Adipocytes2

Marrow stromal cells2

Muscle3

Tumours3

Hydroxyapatite scaffolds1

Biomaterials3

Abstract1

Complete Tissue1

Connective tissue2

Homogenate1

Approaches2

Infection7

Resulting bone loss1

Structural1

Subcutaneous1

Clinical7

Osteoclasts1

Regenerative medicine1

Skeletal1

Cells20

Organ2

Soft19

Femur1

Osteoporosis4

Reconstruction1

Collagen fibers1

Mineral5

BMAT6

Demineralization2

Skin2

Blood7

Inflammation1

Trauma1

Functional1