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  • lipid
  • BMI, HbA1c, serum lipid level, and body fat distribution, which were determined by computed tomography (CT) scan at the umbilical level, were measured and compared before and after troglitazone treatment. (diabetesjournals.org)
  • The purpose of the study was to evaluate the relationship between serum adiponectin and leptin concentrations and body composition, hematological indices and lipid profile parameters in adults. (mdpi.com)
  • These hormone receptors sense a variety of metabolic ligands including lipophilic hormones, dietary fatty acids and their metabolites, and, depending on the varying levels of these ligands, control transcription of genes involved in balancing the changes in lipid balance in the body. (wikipedia.org)
  • The genes activated by PPARG stimulate lipid uptake and adipogenesis by fat cells. (wikipedia.org)
  • hips
  • Women tend to store excess fat underneath the skin, around the hips and thighs, which, although responsible for cosmetic conditions such as cellulite, is much safer than storing fat viscerally as a pot-belly which is more common amongst men. (innovations-report.com)
  • DEXA
  • DEXA uses a whole body scanner and two different low-dose x-rays to read bone mass and soft tissue mass. (clinicaltrials.gov)
  • Change Over Time in Body Fat Distribution [ Time Frame: DEXA performed at the study visit and more than 6 months prior to the study visit (the period of time between the DEXA recorded at the study visit and the previous DEXA ranged from 6 to 36 months). (clinicaltrials.gov)
  • Change over time in total body fat and fat in the limbs and trunk was assessed by dual X-ray absorptiometry (DEXA) in participants for whom a DEXA measurement performed at least 6 months before participation in this study was available. (clinicaltrials.gov)
  • diets
  • During development, some groups of stem cells will go on to become adipose cells - the large globular cells that store and metabolise fats from our diets. (innovations-report.com)
  • citation needed] She did her doctoral dissertation with Judith Rodin at Yale University and Mark Friedman (scientist) at the Monell Chemical Senses Center, focusing on how rodent metabolism changes in response to short term exposure to high fat diets. (wikipedia.org)
  • weight
  • Mean adipokine levels were significantly higher in women ( p ≤ 0.01), adiponectin significantly negatively correlated with body height and weight, systolic blood pressure and absolute LBM and SMM values. (mdpi.com)
  • Only in women, we observed a positive correlation between LEP and body weight, BMI and WHR. (mdpi.com)
  • However, in the case of obesogens that target the PPARα/RXR complex, which when stimulated reduces adipose mass and body weight, there are a few explanations as to how they promote obesity. (wikipedia.org)
  • Within all racial groups, it was found that weight concerns and negative body perceptions were a significant factor in an adolescent's decision to smoke. (wikipedia.org)
  • People are generally considered obese when their body mass index (BMI), a measurement obtained by dividing a person's weight by the square of the person's height, is over 7002294199500000000♠30 kg/m2, with the range 7002245166250000000♠25-30 kg/m2 defined as overweight. (wikipedia.org)
  • Excessive body weight is associated with various diseases and conditions, particularly cardiovascular diseases, diabetes mellitus type 2, obstructive sleep apnea, certain types of cancer, osteoarthritis and asthma. (wikipedia.org)
  • Its twofold objective is to sponsor research and foster support groups in human body weight control. (wikipedia.org)
  • mass index
  • Flegal KM, Carroll MD, Kit BK, Ogden CL (2012) Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. (springer.com)
  • Adjustment for body mass index and for lifestyle risk factors had very little effect on the sex difference in mean intima media thickness. (bmj.com)
  • A 2010 study that followed 11,000 subjects for up to eight years concluded that WHtR is a much better measure of the risk of heart attack, stroke or death than the more widely used body mass index. (wikipedia.org)
  • In people with early-onset severe obesity (defined by an onset before 10 years of age and body mass index over three standard deviations above normal), 7% harbor a single locus mutation. (wikipedia.org)
  • Measurement
  • Perception of body fat was assessed by the Lipodystrophy Severity Grading Scale (LSGS), a standardized measurement of subjective lipoatrophy (fat loss) and lipoaccumulation (fat gain) perceived by the participant and by the physician. (clinicaltrials.gov)
  • To help women meet the perceived ideal female body shape, corset and girdle manufacturers used a calculation called hip spring, the difference between waist and hip measurement (usually 10-12 inches). (wikipedia.org)
  • buttocks
  • Score A reflects the lipoatrophy or fat loss perception at the face, arms, buttocks and legs and ranges from 0-12. (clinicaltrials.gov)
  • Testosterone circulation causes fat cells to deposit around the abdominal and gluteofemoral region, whereas in women oestrogen circulation leads to fat deposits around areas such as thighs, breasts and buttocks. (wikipedia.org)
  • obese
  • On average, obese people have a greater energy expenditure than their normal counterparts due to the energy required to maintain an increased body mass. (wikipedia.org)
  • varies
  • We've known for a while that having a pot-belly suggests someone's risk of developing type 2 diabetes and heart disease is high, but there is still a lot to learn about why body fat distribution varies so much between people. (innovations-report.com)
  • adults
  • 2009: Researchers in the lab of C. Ronald Kahn, MD discover that brown fat is present in some adults, providing a new target for the treatment of obesity. (wikipedia.org)
  • hormones
  • The study, led by Professor Kevin Docherty of the University of Aberdeen, found that adding palmitate (a major component in palm oil) to mouse stem cells affected how they responded to androgen and oestrogen - the sex hormones which normally control the types of fat cells that stem cells become. (innovations-report.com)
  • Some of these proposed pathways include inappropriate modulation of nuclear receptor function which therefore allows the compounds to be classified as endocrine disrupting chemicals that act to mimic hormones in the body, altering the normal homeostasis maintained by the endocrine system. (wikipedia.org)
  • molecular
  • To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. (lu.se)
  • type
  • Effect of troglitazone on body fat distribution in type 2 diabetic patients. (diabetesjournals.org)
  • To expand on this finding, we investigated at the clinical level how long-term administration of troglitazone influences the body fat distribution in type 2 diabetic patients. (diabetesjournals.org)
  • This study evaluated changes in body fat distribution in human immunodeficiency virus type 1 (HIV-1) infected participants who either switched from a zidovudine- plus lamivudine- containing highly active antiretroviral therapy (HAART) regimen to a regimen containing Truvada® (a fixed-dose combination tablet of emtricitabine [FTC, 200 mg] and tenofovir disoproxil fumarate [TDF, 300 mg]) or who remained on a zidovudine- plus lamivudine-containing regimen. (clinicaltrials.gov)
  • appetite
  • Medications may be used, along with a suitable diet, to reduce appetite or decrease fat absorption. (wikipedia.org)
  • glucose
  • The purpose was to determine whether lifestyle interventions have different effects on regional fat in women with normal glucose tolerance vs. impaired glucose tolerance (NGT vs. IGT). (figshare.com)
  • risk
  • Professor Docherty concluded: "The number one way of reducing the number of overweight people is improving diet and encouraging exercise, but we hope our research might eventually offer insights that lead to new treatments including drugs to reduce these high-risk fat stores around organs. (innovations-report.com)
  • patterns
  • In undeveloped countries the ability to afford food, high energy expenditure with physical labor, and cultural values favoring a larger body size are believed to contribute to the observed patterns. (wikipedia.org)
  • change
  • A negative change score indicates fat loss over time and a positive change score indicates fat gain over time. (clinicaltrials.gov)
  • Blood volume is adapted to the change of pressure within the lower part of the body. (wikipedia.org)
  • stable
  • This tendency to store fat, however, would be maladaptive in societies with stable food supplies. (wikipedia.org)
  • study
  • Pilot Phase IV, Multicenter, Randomized, Open-label and Controlled Study to Assess the Evolution of Peripheral Body Fat Distribution After Switching From Zidovudine Containing Backbone to Truvada in HIV-1-infected Patients on HAART (RECOMB Study). (clinicaltrials.gov)
  • The purpose of this study is to compare the body fat distribution in Human Immunodeficiency Virus-1 (HIV-1) infected patients receiving, since the beginning and for at least two years, an antiretroviral therapy based on efavirenz or lopinavir/ritonavir and a combination of tenofovir plus emtricitabine (or lamivudine). (clinicaltrials.gov)
  • intake
  • The neural networks underlying the complex interactions among stressors, body, brain and food intake are now better understood. (wikipedia.org)
  • Diet quality can be improved by reducing the consumption of energy-dense foods, such as those high in fat and sugars, and by increasing the intake of dietary fiber. (wikipedia.org)
  • Nutrition
  • Professor Docherty said "This finding is an important insight as it suggests that nutrition in early development can affect how and where fat is stored in later life. (innovations-report.com)
  • The phrase first appeared in an "official" publication in 1995, as part of a report from a policy working group investigating grocery distribution and food retailing on behalf of the Low Income Project Team of the UK government's Nutrition Task Force. (wikipedia.org)
  • energy
  • Their ability to take advantage of rare periods of abundance by storing energy as fat would be advantageous during times of varying food availability, and individuals with greater adipose reserves would more likely survive famine. (wikipedia.org)
  • cell
  • Two different receptors, alpha and beta fat cell receptors, vary in their ability to facilitate or inhibit fat mobilization. (wikipedia.org)
  • increase
  • The related raise in pH value often entails a strengthening of the connective tissue, leading to an increase of collagen synthesis as well as to improved fat reduction. (wikipedia.org)