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  • Transitions
  • Alzforum first reported on this data from the Phase Transitions in Biology and Disease meeting in Leuven last May ( May 2017 conference news ). (alzforum.org)
  • The liquid-like internal nature of these structures assists in increased efficiency of cellular biochemical processes because these allow for co-presence of functionally related proteins and nucleic acids through the process of coordinated phase transitions and their rapid mixing [1- (termedia.pl)
  • We recently reported that the unexpected discovery that the human interferon (IFN)-inducible "myxovirus resistance protein A" (MxA), which displays antiviral activity against several RNA and DNA viruses, existed in the cytoplasm largely in membrane-less metastable condensates exhibiting rapid reversible tonicity-driven phase transitions on the time-scale of 1-3 minutes [13- (termedia.pl)
  • condensation
  • 2. The method defined in claim 1 wherein said cryogenic liquid is vaporized upon introduction to said liquid phase to form a cold gas which rises in said device into contact with said gas mixture to promote additional condensation of said vaporcomponent. (patentgenius.com)
  • The second edition includes significant new material on the nanoscale and microscale thermophysics of boiling and condensation phenomena and the use of advanced computational tools to create new models of phase-change events. (routledge.com)
  • pathways
  • They also report that arginine methylation inhibits phase transition of FUS, and that these pathways go awry in some cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). (alzforum.org)
  • adhesion
  • The force acting on the liquid is a potential-dependent gradient of adhesion energy between the liquid and a solid insulating surface. (google.com)
  • We demonstrate that in situations where electrostatic bilayer forces and tip-sample adhesion are negligible, phase contrast becomes a mapping of local elastic stiffness variations of the sample. (pnas.org)
  • biological
  • We study the physical origins of phase contrast in dynamic atomic force microscopy (dAFM) in liquids where low-stiffness microcantilever probes are often used for nanoscale imaging of soft biological samples with gentle forces. (pnas.org)
  • Because the natural medium for the study of biological samples is liquid, it is of fundamental importance to develop a proper description of the different working modes of dAFM when the probe and sample are immersed in liquids. (pnas.org)
  • In particular, there is little work on understanding the origins of phase contrast in liquids ( 6 ) where soft cantilevers (stiffness ≲ 1 N/m) with low-quality factors ( Q ≲ 5) are routinely used for the imaging of soft biological samples. (pnas.org)
  • extent
  • We show that this opens up a new energy flow channel for the soft microcantilevers in liquids and that phase contrast really measures the extent of energy transferred to the second eigenmode via tip-sample interaction rather than tip-sample dissipation. (pnas.org)
  • nuclear
  • Nuclear-import receptors and arginine methylation regulate phase separation and aggregation of RNA-binding proteins in the cytosol. (alzforum.org)
  • Four papers in the April 19 Cell reveal that nuclear import receptors (NIRs) potently inhibit and even reverse phase transition and fibril formation of several pathogenic RBPs. (alzforum.org)
  • Examples of such membrane-less organelles include the nucleolus, nuclear speckles, P bodies, stress granules, and more recent discoveries such as cytoplasmic condensates of synapsin or of the DNA sensor cyclic GMP-AMP synthase (cGAS) [1- and even of viral replication complexes [10, and citations therein]. (termedia.pl)
  • samples
  • This miniaturization, in turn, requires methods of rapid and automatic dispensing and manipulation of small volumes of liquids (solvents, reagents, samples etc. (google.com)
  • typically
  • The liquid-like nature of such condensates is typically demonstrated by rapid fluorescence recovery after photo-bleaching (FRAP) experiments as well as by their rapid disassembly (in 15-60 seconds) by 1,6-hexanediol [3, 11, (termedia.pl)
  • Primary effusion lymphoma (PEL) represents a novel B-cell non-Hodgkin's lymphoma (NHL) type associated with Kaposi's sarcoma-associated herpesvirus infection and typically growing as lymphomatous effusions in the body cavities. (bloodjournal.org)
  • main
  • The main symptoms of water retention are: Swollen sensation of slowness in the legs by stagnation of the liquids, swelling in the ankles, legs, swollen abdomen, generalized swelling. (botanical-online.com)
  • severe
  • After training his body to receive a fragment of One For All, labeled as "Super-Power" thanks to a loophole in the registry system, Izuku learns to use twenty percentage of the Quirk's power due to the severe damage it causes his body. (wikipedia.org)
  • often
  • Contrary to the common assumption, phase-contrast images in liquids using soft microcantilevers are often maps of short-range conservative interactions, such as local elastic response, rather than tip-sample dissipation. (pnas.org)
  • second
  • In this article, we build on a recent result ( 11 )-valid for soft microcantilevers tapping on a sample in liquids-that shows the second eigenmode is momentarily excited near times of tip-sample contact. (pnas.org)
  • Report
  • Here we report the identification of a population of E-ring grains that are rich in sodium salts ( 0.5-2% by mass), which can arise only if the plumes originate from liquid water. (thunderbolts.info)
  • state
  • This rapid sensitivity to hexanediol (3-5%) is now used as a simple test for the liquid-like state of the interior of biomolecular condensates [11, (termedia.pl)
  • water
  • The evaporative phase of the cycle purifies water which then replenishes the land with freshwater. (wikipedia.org)
  • Some infiltration stays close to the land surface and can seep back into surface-water bodies (and the ocean) as groundwater discharge. (wikipedia.org)
  • data
  • A.P. Savitskii and L.K. Savitskaya, New data on embrittlement of metals by liquid melts, Doklady ANSSSR , 174 , 5:1072 (1967), in Russian. (springer.com)