• Rizatriptan decreases this widening and returns the blood vessels to their normal size, helping to relieve the pain. (mydr.com.au)
  • But newer migraine drugs known as triptans cause constriction of blood vessels and also bring about a general interruption in the chain of chemical events that leads to a migraine. (rxlist.com)
  • But unlike triptans, they don't narrow your blood vessels. (webmd.com)
  • The biggest danger of triptans is heart attack or stroke in people with previously undiagnosed heart disease or risk factors like obesity and high blood pressure. (tianmedical.com)
  • Ergots are not as targeted as triptans, however, and cause constriction of vessels throughout the body, not just in the brain. (tianmedical.com)
  • Like triptans, they act by constricting the blood vessels. (healthvigil.com)
  • However not like triptans, they don't slender your blood vessels. (ezesavers.com)
  • Dihydroergotamine belongs to a family of medications called ergot alkaloids . (medbroadcast.com)
  • These medications work by constricting blood vessels in the head. (medbroadcast.com)
  • D.H.E. 45 may interact with other migraine headache medicines, zileuton, cold or allergy medications, nicotine , diet pills, stimulants, medication to treat ADHD , antidepressants , antifungal medications, or heart or blood pressure medication. (rxlist.com)
  • These include certain blood pressure medications as well as some antidepressants , anti- seizure drugs, and herbals. (rxlist.com)
  • These medications have anti-inflammatory effects and are thought to narrow the blood vessels in your brain, helping to ease pain. (healthline.com)
  • Ergotamine and its derivative, dihydroergotamine are the cheaper and older medications still being prescribed to treat migraine. (healthvigil.com)
  • If a moderate to severe migraine attack is underway, however, triptan or dihydroergotamine (DHE) medications are recommended. (chemist2u.com.au)
  • Blood pressure-lowering medications help prevent the blood vessels from dilating , which also helps reduce the frequency of attacks. (seattlecrc.com)
  • It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles.The process is the opposite of vasoconstriction, which is the narrowing of blood vessels. (kraneks.by)
  • The vessels that carry blood away from the heart are called arteries. (kraneks.by)
  • High blood pressure adds to the workload of the heart and arteries. (apollopharmacy.in)
  • Hypertension or high blood pressure is a long-term force of the blood against the arteries that may lead to various heart diseases. (apollopharmacy.in)
  • It can damage the blood vessels (arteries) of the brain, heart, and kidneys if it continues for a long time, resulting in a stroke, heart failure or kidney failure. (apollopharmacy.in)
  • Later, the blood vessels dilate or enlarge, leading to increased blood flow and a severe headache. (mountsinai.org)
  • Various theories have been put forward to explain why these vessels tend to dilate. (abdel-gadir.com)
  • During a migraine attack, blood vessels in the brain dilate, or widen, resulting in a throbbing pain. (mydr.com.au)
  • It works by narrowing blood vessels around the brain, stopping pain signals from being sent to the brain, and blocking the release of natural substances that cause pain, nausea, and other symptoms of migraine. (medlineplus.gov)
  • Serious or potentially life-threatening reductions in blood flow to the brain or extremities due to interactions between dihydroergotamine (the active ingredient in Trudhesa) and strong CYP3A4 inhibitors (such as protease inhibitors and macrolide antibiotics) have been reported rarely. (trudhesa.com)
  • Sumatriptan relieves migraine headaches by constricting these blood vessels. (medbroadcast.com)
  • Sumatriptan has caused serious side effects in some people, especially people who have heart or blood vessel disease. (mayoclinic.org)
  • Sumatriptan may elevate blood pressure in individuals with or without a history of high blood pressure. (hdkino.org)
  • Individuals with uncontrolled high blood pressure should not use sumatriptan. (hdkino.org)
  • Monoamine oxidase inhibitors or MAOIs , for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine ( Matulane ), may reduce the breakdown of sumatriptan in the liver , leading to increased blood levels and side effects of sumatriptan. (hdkino.org)
  • Verapamil (Calan, generic), a drug for high blood pressure, is typically the first choice of medication used for long-term prevention. (adam.com)
  • One of the classic ways of tackling a migraine is through a medication called Dihydroergotamine, or DHE for short. (encoredocs.com)
  • Dihydroergotamine, a derivative, can be used in treating migraine. (britannica.com)
  • Action Constricts peripheral and cranial blood vessels, depresses central vasomotor centers, and reduces extracranial blood flow. (medicscientist.com)
  • Tumour size, cavernous sinus invasion, traction or displacement of intracranial pain-sensitive structures such as blood vessels, cranial nerves and dura mater, and hormonal hypersecretion are implicated causes. (medscape.com)
  • Serious and/or life-threatening peripheral ischemia has been associated with the coadministration of DIHYDROERGOTAMINE with potent CYP 3A4 inhibitors including protease inhibitors and macrolide antibiotics. (rxlist.com)
  • Ergotamine and dihydroergotamine, two notable members of this category, are potent vasoconstrictors that alleviate migraine symptoms by narrowing blood vessels in the brain. (pharmaoffer.com)
  • Obstruction of blood flow in a coronary artery by a blood clot (thrombus). (kraneks.by)
  • Researchers are not sure what causes a migraine, but they know it involves changes in the blood flow to the brain. (mountsinai.org)
  • Midodrine does not cross the blood-brain barrier and is not associated with CNS effects. (scireproject.com)
  • It is known that estrogen is able to cross the blood-brain-barrier freely. (sunshinentc.com)
  • When stimulated, the nerve may release substances that cause painful inflammation in the blood vessels of the brain (cerebral blood vessels) and the layers of tissues that cover the brain (meninges). (msdmanuals.com)
  • ZOMIG is a headache medicine that narrows blood vessels around the brain. (pricepropharmacy.com)
  • Prostaglandin E 1 also dilates blood vessels, and it is sometimes administered by intravenous infusion to treat peripheral vascular disease . (britannica.com)
  • On the other hand, excessive local production of oestrogens could lead to dilatation and stasis of blood in the pelvic veins leading to pelvic pain in women with abnormal ovarian function [Kroon and Reginald, 2005]. (abdel-gadir.com)
  • Veins are vessels that return blood to the heart. (kraneks.by)
  • This increased or decreased blood pressure causes the veins & valves to contract and expand accordingly putting pressure on the blood vessels and the heart. (kraneks.by)
  • By blocking these receptors, inflammation is reduced and the vessels are able to constrict. (tianmedical.com)
  • They act by constricting the blood vessels and reducing inflammation, thus giving relief from pain. (healthvigil.com)
  • Because CYP 3A4 inhibition elevates the serum levels of DIHYDROERGOTAMINE, the risk for vasospasm leading to cerebral ischemia and/or ischemia of the extremities is increased. (rxlist.com)
  • Tell your doctor if you have heart disease or blood circulation problems, including heart rhythm problems, ischemic bowel disease, peripheral vascular disease, or a history of heart attack, angina (chest pain), stroke, or transient ischemic attack (TIA). (limamemorial.org)
  • At first, blood vessels narrow or constrict, reducing blood flow and leading to visual disturbances, difficulty speaking, weakness, numbness, or tingling sensation in one area of the body, or other similar symptoms. (mountsinai.org)
  • Symptoms are attributed to ischaemia of the tissues and blood vessels themselves subsequent to slow blood drainage and stasis especially following increased intra-abdominal pressure. (abdel-gadir.com)
  • Betamerit-XL 50 Tablet 15's belongs to a group of medicines called "Antihypertensive" used alone or together with other drugs to treat high blood pressure (hypertension), symptoms caused by an overactive thyroid gland, heart-related chest pain (angina), heart rhythm disorder (arrhythmia). (apollopharmacy.in)
  • In case of circulatory collapse (poor blood circulation). (zeepedia.com)
  • Ergotamine should not be taken by patients with liver or kidney disease, heart disease, circulation problems, high blood pressure, or an infection of the blood. (optionrx.com)
  • Tosymra is not for people with risk factors for heart disease (high blood pressure or cholesterol, smoking, overweight, diabetes, family history of heart disease) unless a heart exam is done and shows no problem. (tosymra.com)
  • However, the primary metabolite reaches peak blood concentrations about 1 to 2 hours after a dose of Midodrine and has a half-life of about 3 to 4 hours. (scireproject.com)
  • Lowering blood pressure reduces the risk of stroke, heart attack and heart-related chest pain (angina). (apollopharmacy.in)
  • HA719 trade name] is used in combination with other HIV medicines to reduce the amount of virus in your blood and keep it at a low level. (who.int)
  • This lowers your blood pressure and reduces the risk of having a stroke, a heart attack, other heart problems or kidney problems in the future. (apollopharmacy.in)
  • This, in turn, lowers your overall body's blood pressure and helps in reducing the risk of having a stroke, heart problems, or kidney problems in the future. (apollopharmacy.in)
  • Dihydroergotamine is most effective if used at the first sign of a migraine headache with or without aura (warning signs that occur prior to the onset of a migraine headache). (medbroadcast.com)
  • Orthostatic hypotension (sudden lowering of blood pressure n standing) might occur so patients using Betamerit-XL 50 Tablet 15's should get up with caution. (apollopharmacy.in)