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  • haemoglobin
  • There are typically low levels in haemolytic anaemia (haptoglobin is a suicide molecule which binds with free haemoglobin released from red blood cells and these complexes are rapidly removed by phagocytes). (wikipedia.org)
  • toward
  • As a result, molecules that are negatively charged such as deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and protein are pulled toward the positive end of the gel. (encyclopedia.com)
  • molecules
  • As a result, molecules that are negatively charged such as deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and protein are pulled toward the positive end of the gel. (encyclopedia.com)
  • They accurately tease-out vanishingly small concentrations of proteins and other molecules that help give a picture of overall health or signal the presence of specific diseases. (phys.org)
  • They've engineered a new compound from two molecules that occur naturally in blood, to use solar energy to split water molecules into hydrogen and oxygen. (autoblog.com)
  • The lipid bilayer is the barrier that keeps ions, proteins and other molecules where they are needed and prevents them from diffusing into areas where they should not be. (wikipedia.org)
  • The predicted nephrin protein belongs to the immunoglobulin family of cell adhesion molecules and is specifically expressed in renal glomeruli. (wikipedia.org)
  • The blood-brain barrier is formed by brain endothelial cells and it allows the passage of water, some gases, and lipid-soluble molecules by passive diffusion, as well as the selective transport of molecules such as glucose and amino acids that are crucial to neural function. (wikipedia.org)
  • concentration
  • Among several fat-secreted proteins now associated with insulin activity, blood concentration of RBP4 is thus far the strongest predictor of a person's visceral fat load and insulin resistance. (nih.gov)
  • The normal concentration of globulins in human blood is about 2.6-4.6 g/dL. (wikipedia.org)
  • Menkes disease (Menkes kinky hair syndrome) (rare - UK incidence 1/100,000) Copper deficiency Aceruloplasminemia Greater-than-normal ceruloplasmin levels may indicate or be noticed in: copper toxicity / zinc deficiency pregnancy oral contraceptive pill use lymphoma acute and chronic inflammation (it is an acute-phase reactant) rheumatoid arthritis Angina Alzheimer's disease Schizophrenia Obsessive-compulsive disorder Normal blood concentration of ceruloplasmin in humans is 20-50 mg/dL. (wikipedia.org)
  • Severe symptoms are usually due to acute elevation of the plasma sodium concentration to above 157 mmol/L (normal blood levels are generally about 135-145 mmol/L for adults and elderly). (wikipedia.org)
  • proteoglycan
  • Normally, joint cartilages have proteoglycan complexes, which are proteins with side chains made of glycosaminoglycans such as keratan sulfate and chondroitin sulfate attached to strands of hyaluronic acid. (wikipedia.org)
  • cells
  • Contrary to popular belief, haemoglobin is not a blood protein, as it is carried within red blood cells, rather than in the blood serum. (wikipedia.org)
  • This rejuvenated the stem cells in the bone marrow of the older mice that replenish their blood , and led to a wave of studies comparing the blood of old and young mice to try and identify the youth-giving substance. (newscientist.com)
  • The volume of the blood vessels in their brain increased by 50 per cent and the number of brain stem cells by 29 per cent. (newscientist.com)
  • We have examined the interactions of hemoglobin containing liposomes and of liposomes composed of polymerizable phospholipids with blood cells and proteins. (dtic.mil)
  • Bilayers are particularly impermeable to ions, which allows cells to regulate salt concentrations and pH by transporting ions across their membranes using proteins called ion pumps. (wikipedia.org)
  • The innate immune system includes physical and chemical barriers, blood proteins and phagocytic cells. (wikipedia.org)
  • When there is a trauma in body, cells at site start the cascade of blood clotting and fibrin is the first scaffold formed normally. (wikipedia.org)
  • Cells of the barrier actively transport metabolic products such as glucose across the barrier with specific proteins. (wikipedia.org)
  • At the interface between blood and the brain, endothelial cells are stitched together by these tight junctions, which are composed of smaller subunits, frequently biochemical dimers, that are transmembrane proteins such as occludin, claudins, junctional adhesion molecule (JAM), or ESAM, for example. (wikipedia.org)
  • Each of these transmembrane proteins is anchored into the endothelial cells by another protein complex that includes ZO-1 and associated proteins. (wikipedia.org)
  • The BBB is distinct from the quite similar blood-cerebrospinal fluid barrier, which is a function of the choroidal cells of the choroid plexus, and from the blood-retinal barrier, which can be considered a part of the whole realm of such barriers. (wikipedia.org)
  • Acute
  • citation needed] Frequent, severe infections Malnutrition and related diseases Blood clots Acute kidney failure Chronic kidney failure End-stage kidney disease Kestilä M, Männikkö M, Holmberg C, Tryggvason K, Peltonen L (February 1994). (wikipedia.org)
  • concentrations
  • Researchers found that the drugs work the same -- at least in heart patients, older men with high blood pressure and diabetics -- regardless of the results of a test that looks for concentrations of so-called C-reactive protein. (bio-medicine.org)
  • large
  • In the current study, Carneiro identified a large set of proteins that stick to SERT, presuming they might control SERT activity. (bio-medicine.org)
  • A urinalysis reveals large amounts of protein and the presence of fat in the urine. (wikipedia.org)
  • They belong to a large group of binding proteins mediating the transport and availability of a wide variety of cargo substances in the bloodstream. (wikipedia.org)
  • immune
  • Even people with low levels of LDL cholesterol and the protein -- those thought to perhaps be immune to the drug's effects -- showed benefits. (bio-medicine.org)
  • Sequence
  • Collagen originated sequence is DGEA and many other ECM protein originated RGD sequence can be given as other examples. (wikipedia.org)
  • Secondary structure of the 5' UTR sequence conserved between humans and gibbon contain sequence recognized by to RBMX, Ras & Rab proteins. (wikipedia.org)
  • extracellular
  • FBLN1 is the gene encoding fibulin-1, an extracellular matrix and plasma protein. (wikipedia.org)
  • The blood-brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS). (wikipedia.org)
  • HEMOGLOBIN
  • Blood samples of coalfish from Norwegian and Icelandic waters were collected and analyzed for hemoglobin, serum protein, and serum esterase variations in order to study the relation between the two coalfish stocks. (bibsys.no)
  • clots
  • Undiagnosed cases are often fatal in the first year due to blood clots, infections or other complications. (wikipedia.org)
  • plasma
  • Blood proteins, also termed plasma proteins or serum proteins, are proteins present in blood plasma. (wikipedia.org)
  • Current research regarding blood plasma proteins is centered on performing proteomics analyses of serum/plasma in the search for biomarkers. (wikipedia.org)
  • In a separate study, a team led by Tony Wyss-Coray at the Stanford School of Medicine in California gave 18-month-old mice, the equivalent of mid-to-late middle age, eight injections of blood plasma taken from 3-month-old mice. (newscientist.com)
  • The studies show the old brain is plastic and can recover function, and that this can be done so simply, just by injecting 'young' blood plasma," he says. (newscientist.com)
  • They want to inject blood plasma from young, healthy donors into people with Alzheimer's disease to see if it improves their brain function. (newscientist.com)
  • Chinese researchers say a protein that makes up about 60% of protein mass in blood plasma can be used as a prognostic indicator in people on chemotherapy for malignant pleural mesothelioma. (prweb.com)
  • Like any other plasma protein, levels drop in patients with hepatic disease due to reduced synthesizing capabilities. (wikipedia.org)
  • because the blood proteins reduce interior permeability, less plasma fluid can exit the vessel. (wikipedia.org)
  • levels
  • MONDAY, Dec. 24 (HealthDay News) -- People suffering from depression or psychological distress appear to have higher than normal blood levels of C-reactive protein (CRP), an indicator of inflammatory disease, according to new research from Denmark. (medicinenet.com)
  • Many children with autism have elevated blood levels of serotonin a c. (bio-medicine.org)
  • Many children with autism have elevated blood levels of serotonin a chemical with strong links to mood and anxiety. (bio-medicine.org)
  • Prior research had fingered the integrin beta3 gene as a determinant of blood serotonin levels and, independently, as a risk factor for autism, Blakely said. (bio-medicine.org)
  • FRIDAY, Jan. 28 (HealthDay News) -- A new study debunks the idea that the cholesterol-fighting drugs known as statins work better in people with high levels of a certain protein and may not work at all in those with low levels. (bio-medicine.org)
  • However, Fonarow said, the findings do not say whether levels of the protein will affect the effectiveness of the drugs in healthy people. (bio-medicine.org)
  • Some research has linked levels of C-reactive protein to better or worse effectiveness. (bio-medicine.org)
  • The study, published online Jan. 28 in The Lancet , found no link between levels of the protein and benefits from the drug. (bio-medicine.org)
  • In the big picture, Fonarow said, people shouldn't worry about levels of the protein in their bodies. (bio-medicine.org)
  • Patients interested in their cardiovascular health should be most focused on achieving healthy LDL-cholesterol, blood pressure and body weight levels along with engaging in daily exercise, eating a healthy diet, not smoking and avoiding secondhand smoke," he said. (bio-medicine.org)
  • For the study, Coccaro looked at levels of two types of indicators of inflammation in blood: C-reactive protein and interleukin-6. (drugs.com)
  • Elevated levels of these proteins have been linked with aggressive and impulsive behaviors in people and animals. (drugs.com)
  • Now scientists have found that this type of fat, compared to other types, produces higher levels of a protein that can be detected in the blood. (nih.gov)
  • In the new study, reported in the July 2007 issue of the journal Cell Metabolism , the scientists set out to determine if blood levels of RBP4 were directly influenced by visceral fat, which surrounds abdominal organs and has been linked to disease risk. (nih.gov)
  • They measured blood levels of RBP4 in 130 obese and 66 lean people. (nih.gov)
  • Blood levels of RBP4 measured up to 3 times higher in obese than in lean people. (nih.gov)
  • Those with higher blood levels of RBP4 had a corresponding increase in abdominal fat and a reduction in insulin sensitivity, regardless of their age, gender or body mass index (a ratio of weight to height). (nih.gov)
  • Mechanisms of low ceruloplasmin levels: Gene expression genetically low (aceruloplasminemia) Copper levels are low in general Malnutrition/trace metal deficiency in the food source Copper does not cross the intestinal barrier due to ATP7A deficiency (Menkes disease) Delivery of copper into the lumen of the ER-Golgi network is absent in hepatocytes due to absent ATP7B (Wilson's disease) Copper availability doesn't affect the translation of the nascent protein. (wikipedia.org)
  • Low blood protein levels can result in a falsely high sodium measurement. (wikipedia.org)
  • vessels
  • Note that while most heavy chains or whole immunoglobulins remain within blood vessels, light chains frequently escape and are excreted by the kidneys into urine, where they take the name of Bence Jones protein. (wikipedia.org)
  • Chemistry
  • A simple cut to the skin unleashes a complex cascade of chemistry to stem the flow of blood. (phys.org)
  • researchers
  • Blood tests of people who display the hostile outbursts that characterize a psychiatric illness known as intermittent explosive disorder show signs of inflammation, researchers say. (drugs.com)
  • naturally
  • These two proteins are produced naturally in human breast milk and are used globally in infant formula and rehydration products. (wikipedia.org)
  • molecule
  • Porphyrin is the molecule that carries oxygen around in the blood-stream. (autoblog.com)
  • In recent years scientists at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston have been exploring the unexpected complexity of the molecule retinol-binding protein (RBP4), once thought to have the sole purpose of ferrying vitamin A (retinol) through the bloodstream. (nih.gov)
  • function
  • Proteins can function as receptors, to allow the microorganism to adhere to the surface of a host cell. (encyclopedia.com)
  • Vicilin and legumin, from peas and other legumes, function as protein storage within seeds. (wikipedia.org)
  • Integral membrane proteins function when incorporated into a lipid bilayer, and they are held tightly to lipid bilayer with the help of an annular lipid shell. (wikipedia.org)
  • mutation
  • Notably, Edwin Cook, M.D., at the University of Illinois at Chicago and a co-author on the study, had shown that the same integrin beta3 mutation that elevates SERT activity also predicts elevated blood serotonin. (bio-medicine.org)
  • The most common Finnish mutation was a deletion of 2 nucleotides in exon 2 (602716.0001), resulting in a frameshift and a truncated protein. (wikipedia.org)
  • abundant
  • All types of liposomes studied bound a variety of serum proteins with IgG being the most abundant component in each case. (dtic.mil)
  • Fetuin is more abundant in fetal blood, hence the name "fetuin" (from Latin, fetus). (wikipedia.org)
  • barrier
  • Astrocytes have been claimed to be necessary to create the blood-brain barrier. (wikipedia.org)
  • A few regions in the brain, including the circumventricular organs, do not have a blood-brain barrier. (wikipedia.org)
  • The pineal gland secretes the hormone melatonin "directly into the systemic circulation", thus melatonin is not affected by the blood-brain barrier. (wikipedia.org)
  • Originally, experiments in the 1920s seemed to show that the blood-brain barrier (BBB) was still immature in newborns. (wikipedia.org)
  • research
  • Reviewer, Cancer Research Journal Sigma Xi member Speaker, 112th Annual Meeting in St. Louis, American Association for the Advancement of Science, March 1946 Speaker, 1947 Meeting, National Academy of Sciences, American Association for the Advancement of Science, Blood Protein Studies with Labeled Elements. (wikipedia.org)
  • diagnostic
  • Blood tests are important diagnostic tools. (phys.org)
  • The blood test to evaluate inflammation won't be a diagnostic test, however, because the disorder is diagnosed by observation and reports of behavior. (drugs.com)
  • brains
  • A protein in blood can repair age-related damage in the brains and muscles of old mice, returning them to a more youthful state. (newscientist.com)
  • We dont think the platelet itself contributes to autism, said Blakely, but rather we believe that the brains serotonin transporter may be controlled by integrin proteins in a very similar manner. (bio-medicine.org)
  • cleavage
  • This enzyme catalyses the following chemical reaction Specifically activates several components of the blood clotting system, including coagulation factor X, coagulation factor IX and protein C by cleavage of -Arg- bonds. (wikipedia.org)
  • peripheral
  • Evaluation of cytotoxicity in Human noncancer cells indicated that the compounds 3i and 3m were practically ineffective in quiescent peripheral blood lymphocytes, and may have a selective antiproliferative activity against cancer cells. (deepdyve.com)
  • nutrients
  • Poor nutrition makes wounds take longer to heal, according to Drugs.com, which states that the most important nutrients for wound healing are protein, zinc and vitamin C. To ensure optimum wound healing, you should consume the recommended level of vitamin C and zinc through food sources. (livestrong.com)
  • In developmental biology, choriogenesis is the formation of the chorion, an outer membrane of the placenta that eventually forms chorionic villi that allow the transfer of blood and nutrients from mother to fetus. (wikipedia.org)
  • indicates
  • p>This indicates the type of evidence that supports the existence of the protein. (uniprot.org)
  • Prolonged bleeding from a venepuncture or heelprick is another common early sign of haemophilia, these signs may lead to blood tests which indicates haemophilia. (wikipedia.org)
  • The cause of MSA is uncertain and no specific risk factor has been identified, although research indicates that a prion form of the alpha-synuclein protein may cause the disease. (wikipedia.org)
  • enzyme
  • The crystal structure of the MenH enzyme in E.coli (SHCHC synthase) exists as a complex of three protein molecules shown in the diagram. (wikipedia.org)
  • Russellysin (EC 3.4.24.58, Russell's viper venom factor X activator, RVV-X, blood-coagulation factor X activating enzyme, metalloproteinase RVV-x, Vipera russelli proteinase, Russell's viper blood coagulation factor X activator, RVV-V) is an enzyme. (wikipedia.org)
  • make
  • Eggs are high in protein, healthy fats and they can make you feel full while having a very low amount of calories. (mylifewithnodrugs.com)
  • About 5-10% of people with haemophilia A are affected because they make a dysfunctional version of the factor VIII protein, while the remainder are affected because they produced factor VIII in insufficient amounts (quantitative deficiency). (wikipedia.org)
  • These biochemicals can be joined together to make polymers such as DNA and proteins, essential macromolecules of life. (wikipedia.org)
  • brain
  • Dr. Skovronsky established Avid Radiopharmaceuticals in July 2005 with the goal of finding a dye that could be injected into the body, would cross the blood-brain barrier and attach itself to amyloid protein deposits in the brain. (wikipedia.org)
  • Brain ischemia (a.k.a. cerebral ischemia, cerebrovascular ischemia) is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. (wikipedia.org)
  • An interruption of blood flow to the brain for more than 10 seconds causes unconsciousness, and an interruption in flow for more than a few minutes generally results in irreversible brain damage. (wikipedia.org)
  • Focal brain ischemia occurs when a blood clot has occluded a cerebral vessel. (wikipedia.org)
  • Global brain ischemia occurs when blood flow to the brain is halted or drastically reduced. (wikipedia.org)
  • Human
  • A study of human blood group systems and proteins in the 1950s suggested that the Andamanese peoples were more closely related to Oceanic peoples than African pygmy peoples. (wikipedia.org)
  • different
  • p>When browsing through different UniProt proteins, you can use the 'basket' to save them, so that you can back to find or analyse them later. (uniprot.org)
  • By now you probably figured out that Gaspari Nutrition researchers pay close attention to the research trends, which is why we took a different approach to pushing the limits of blood engorged muscle. (priceplow.com)
  • cause
  • In addition, if it turns out these gut bacteria are effective and accurate markers of Alzheimer's disease cause or progression, or both, they might be useful as a non-invasive screening tool-a simple blood test. (medicalxpress.com)
  • Tumors are one cause of blood vessel compression. (wikipedia.org)
  • muscle
  • Hibernating bears are able to recycle their proteins and urine, allowing them both to stop urinating for months and to avoid muscle atrophy. (wikipedia.org)
  • individuals
  • In right-dominant individuals the blood supply is from the right coronary artery while in left dominant individuals it originates from the left circumflex artery. (wikipedia.org)
  • level
  • Purpose Review aberrations of insulin signaling to atypical proteins kinase C (aPKC) in muscles and liver that generate cardiovascular risk elements, including, weight problems, hypertriglyceridemia, hypercholesterolemia, insulin level of resistance and blood sugar intolerance in type 2 diabetes mellitus (T2DM), and obesity-associated metabolic symptoms (MetSyn). (biomasswars.com)
  • supply
  • The blood supply of the AV node is from the atrioventricular nodal branch. (wikipedia.org)
  • Reperfusion injury is classified as the damage that ensues after restoration of blood supply to ischemic tissue. (wikipedia.org)
  • source
  • For all of you who are working out and thus working towards losing weight, you should eat beans since they are an excellent source of protein. (mylifewithnodrugs.com)
  • p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc. (uniprot.org)
  • correct
  • be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein. (uniprot.org)
  • result
  • Further, irregular heartbeats may result in formation of blood clots, thus leading to oxygen deprivation to all organs. (wikipedia.org)