ObesityMellitusCircumferenceInsulin resistanceSystolic and diastolicHypertensionMetabolismWaistCholesterolSerumPressureLevelsGestational diabetesLipoproteinTypeMetabolicObese patientsHyperlipidemiaMyocardial infarctionRenalUric acidDisordersBaselineComplicationsRiskInflammatoryFatsFavorableBiomarkersHomeostasisOverweightProfileConcentrationSignaling pathwayPhysicalStatinsLipoproteinsDiagnosisSignificantlyHighChronicPatientsResults
Obesity24
- [ 1-3 ] The prevalence of NAFLD increases in subjects with obesity, the metabolic syndrome (MetS), or type 2 diabetes mellitus (T2DM). (medscape.com)
- There was a statistically significant association of triglycerides and HDL-C with increasing age, female sex, obesity, physical inactivity and poor glycaemic control of diabetes. (who.int)
- Humans with obesity can develop a number of health problems, including high blood pressure and diabetes, that can ultimately lead to heart disease. (nih.gov)
- Increasing abdominal obesity was independently associated with fatal and non-fatal heart attacks and strokes, regardless of other risk factors (such as smoking, diabetes, hypertension, blood pressure, blood lipids and body mass index [BMI]) and secondary prevention treatments. (escardio.org)
- In our study, patients with increasing levels of abdominal obesity still had a raised risk for recurrent events despite being on therapies that lower traditional risk factors connected with abdominal obesity - such as anti-hypertensives, diabetes medication and lipid lowering drugs. (escardio.org)
- The database of interventions allows the user to easily search for multisector, collaborative, evidence-based interventions to address the underlying causes of the greatest morbidity and mortality in the United States: tobacco use and exposure, physical inactivity, unhealthy diet, high cholesterol, high blood pressure, diabetes, and obesity. (cdc.gov)
- Of particular concern is emerging evidence indicating that maternal obesity and gestational diabetes may lead to an increase in neonatal weight and body adiposity. (nih.gov)
- The purpose of this RFA is to solicit applications investigating the effect of maternal obesity and diabetes on mechanisms that could potentially contribute to obesity, cancer, cardiovascular or metabolic disease in the offspring. (nih.gov)
- Conclusions Compared with non-surgical treatment of obesity, bariatric surgery leads to greater body weight loss and higher remission rates of type 2 diabetes and metabolic syndrome. (bmj.com)
- 3 Obesity is associated with an increased risk for type 2 diabetes, hypertension, dyslipidaemia, cardiovascular diseases, musculoskeletal disorders (such as osteoarthritis), certain types of cancer, and mortality. (bmj.com)
- More than 32.5 , and you must have an obesity-associated disorder such as Type 2 diabetes. (gleneagles.com.sg)
- One of the main goals of obesity treatment is to reduce the overall cardiometabolic risk, which is largely determined by atherogenic changes in the blood lipid spectrum. (weight-loss-easy.com)
- The atherogenic effect of obesity is mediated by a number of mechanisms, the most important of which are dysregulation of lipid and lipoprotein metabolism at various levels, inhibition of the fibrinolysis system, secretion of pro-inflammatory cytokines by adipocytes. (weight-loss-easy.com)
- The most characteristic disorders of lipid metabolism for people with obesity and overweight are hypertriglyceridemia and a decrease in HDL cholesterol levels. (weight-loss-easy.com)
- Since orlistat has been used in obesity pharmacotherapy for more than 10 years, the results of numerous randomized, placebo-controlled studies allow not only to evaluate the effectiveness of the drug for the treatment of obesity by the degree of weight loss, but also to evaluate the effect of orlistat on cardiometabolic risk factors, in particular, lipid levels blood. (weight-loss-easy.com)
- Platelet count (PLT) is associated positively with lung cancer risk but has a more complex association with body mass index (BMI), positive only in women (mainly never smokers) and inverse in men (mainly ever smokers), raising the question whether platelets interact with obesity in relation to lung cancer risk. (biomedcentral.com)
- Maternal body mass index in early pregnancy is associated with overweight and obesity in children up to 16 years of age. (vgregion.se)
- Adolescents with type 1 diabetes and obesity present higher cardiovascular risk and ambulatory blood pressure measurements (ABPM) has been shown to predict vascular events, especially by identifying the nondipper status. (biomedcentral.com)
- In recent years hypertension has shown an increase in the prevalence among adolescents and type 1 diabetes and obesity are two conditions with higher risk [ 2 ]. (biomedcentral.com)
- Obesity (p = 0.001) and higher body mass index (p = 0.002) were associated with fewer lesions. (kaiserpermanente.org)
- History of intracerebral hemorrhage was not significantly associated with any CV risk factors, however, we found borderline associations of hemorrhage with obesity (p = 0.062), systolic blood pressure (p = 0.083) and pack-years of cigarette smoking (p = 0.055). (kaiserpermanente.org)
- Although age, gender, obesity, body mass index and systolic blood pressure may influence familial CCM1 disease severity, further longitudinal studies in larger sample sizes are essential to confirm these findings. (kaiserpermanente.org)
- The prevalence of type 2 diabetes has been steadily increasing worldwide due to factors such as obesity, dietary choices, and physical activity levels. (medtigo.com)
- Omega-3 fatty acid compositions comprising eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are provided, where the compositions are useful for treating, reducing the occurrence of, or preventing major adverse cardiovascular events or major coronary events in patients who have established cardiovascular disease without prior myocardial infarction, preventing their further progression, and treating underlying risk factors for CVD such as hypertension, dyslipidemia, obesity and/or diabetes. (patsnap.com)
Mellitus13
- In this paper, we propose a new method to analyze the risk factors of coronary heart disease (CHD) and their correlation with inflammatory factors in patients with type 2 diabetes mellitus (T2DM). (hindawi.com)
- Type 2 diabetes mellitus (T2DM) is one of the most important risk factors for coronary heart disease. (hindawi.com)
- The European Heart Survey shows that up to 60 percent of CHD patients are complicated with diabetes mellitus (DM) [ 4 ]. (hindawi.com)
- Background: There is a paucity of data on the coverage of diabetes mellitus (DM) complications screening in primary healthcare facilities in South Africa (SA). (researchgate.net)
- 3. The interactive effects of pre-pregnancy body mass index, thyroid function, and blood lipid levels on the risk of gestational diabetes mellitus: a crossover analysis. (nih.gov)
- 4. [Interaction between Abnormal Prepregnancy Body Mass Index and Hyperlipidemia during Pregnancy on the Risk of Gestational Diabetes Mellitus]. (nih.gov)
- Diagnóstico y monitorización de la diabetes mellitus desde el laboratorio. (who.int)
- Although diabetes mellitus is an established risk factor for coronary heart disease (CHD) and stroke, a number of questions remain. (bmj.com)
- Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. (bmj.com)
- 4 of these 16 studies included patients with type 2 diabetes mellitus (T2DM), in 5 studies patients had at least one of the risk factors for cardiovascular diseases (arterial hypertension, dislipidemia). (weight-loss-easy.com)
- The increasing ownership of mobile phones and advances in hardware and software position these devices as cost-effective personalized tools for health promotion and management among women with gestational diabetes mellitus (GDM). (jmir.org)
- Patient conceptions of treatment with metformin in recently diagnosed type 2 diabetes mellitus. (vgregion.se)
- Observational studies have shown improvement in patients with type 2 diabetes mellitus after bariatric surgery. (nih.gov)
Circumference8
- Demographic and clinical data, body mass index and waist circumference, and fasting blood samples were taken to estimate the glucose and lipid profile. (who.int)
- The primary outcomes included repeated measures of body mass index (BMI), waist circumference, body fat, serum lipids, systolic and diastolic blood pressure (DBP) levels in childhood. (nih.gov)
- Maintaining a healthy waist circumference is important for preventing future heart attacks and strokes regardless of how many drugs you may be taking or how healthy your blood tests are. (escardio.org)
- Another study found that subjects with type 2 diabetes had significantly more weight loss, with decreased body mass index and waist circumference, on a Paleo diet compared with a traditional diabetic diet. (healthcanal.com)
- A review of randomized controlled trials supported the finding that the Paleo diet leads to short-term improvements in weight, body mass index, and waist circumference. (healthcanal.com)
- Baseline characterisics were well matched: body mass index (BMI) 37, weight 106 kg, weight circumference 115 cm, glycated hemoglobin level 7.7%, and total cholesterol 200 mg/dl. (acc.org)
- However, the body weight, body mass index, and waist circumference had significantly decreased after 4-week intervention in both groups, but high sensitivity C-reactive protein was lowered only in glucomannan noodles group. (tmu.edu.tw)
- Moreover, the 24 individuals with type 2 diabetes had significantly decreased body weight, BMI, waist circumference, hs-CRP, and glycated hemoglobin after glucomannan noodles intervention. (tmu.edu.tw)
Insulin resistance11
- However, given the complex and bi-directional relationships between NAFLD, insulin resistance and chronic hyperglycaemia, it is extremely difficult to distinguish whether NAFLD is a cause or a consequence of insulin resistance and type 2 diabetes. (medscape.com)
- In conclusion, progressive liver disease and type 2 diabetes are divergent though inter-related consequences of insulin resistance and the metabolic syndrome. (medscape.com)
- As an early clinical expression of insulin resistance and metabolic syndrome, AGA is related to being an increased risk factor for cardiovascular diseases, glucose metabolism disorders, type 2 diabetes, and enlargement of the prostate. (wikipedia.org)
- We measure visceral fat and the fat content of the heart, liver, and various muscle types and correlate these measurements with metabolic and physiological markers, including body mass index, cardiac function, insulin resistance, and blood lipid profiles. (nih.gov)
- These conditions include increased blood pressure, high blood sugar and insulin resistance (diabetes) as well as raised blood lipid levels. (escardio.org)
- Objective: Insulin resistance, changes in lipid parameters, and cardiometabolic adverse events have been reported in some patients during clinical trials of antipsychotic agents. (psychiatrist.com)
- The present study examined whether the triglyceride/high-density lipoprotein (HDL) ratio can be used as a better surrogate than other conventional lipid measures (low-density lipoprotein [LDL], HDL, triglyceride) in predicting insulin resistance and LDL particle size in nondiabetic patients with schizophrenia. (psychiatrist.com)
- Additionally, there is an association between radiation exposure and heightened inflammation, a well-known factor in insulin resistance and the development of diabetes," explains lead author Dr. Hu. (medicalxpress.com)
- A Paleolithic-style diet may benefit those with diabetes who struggle with insulin resistance and high blood sugar levels. (healthcanal.com)
- The index for homeostasis model assessment of insulin resistance (HOMA-IR) improved significantly after bariatric surgery. (nih.gov)
- However, Vest et al stress that SOS showed that it was the baseline degree of insulin resistance, rather than initial body-mass index (BMI) or the amount of weight lost, that was most predictive of CV benefit. (medscape.com)
Systolic and diastolic4
- triglycerides (TG), c-reactive protein (CRP), 8-iso-prostaglandin-F2alpha (8-iso-PGF2α), adiponectin and systolic and diastolic blood pressure (SBP and DBP, respectively) were assessed at clinic visits every 6 months. (nih.gov)
- Among 394 persons not on anti-hypertensive medication, linear regression analysis demonstrated a significant positive relation between serum PCB level and both systolic and diastolic blood pressure. (cdc.gov)
- Significant positive associations were also observed between PCB concentrations and systolic and diastolic blood pressure even in normotensive ranges. (cdc.gov)
- For each subject we performed systolic and diastolic Ambulatory Blood Pressure Measurements (ABPM) during wakefulness and sleep recording blood pressure every 30 min for 24 h with the Tonoport V/2 GE CardioSoft V6.51 device. (biomedcentral.com)
Hypertension14
- Hypertension also increased with body mass index (BMI), but was not related to total serum lipids levels, gender, smoking or exercise. (cdc.gov)
- Serum PCBs, especially those congeners with multiple ortho chlorines, seem to be important factors in regulation of blood pressure and hypertension. (cdc.gov)
- Hypertension (HTN) or high blood pressure, sometimes called arterial hypertension, is a chronic medical condition in which the blood pressure in the arteries is elevated. (ayurvaid.com)
- As per WHO-ISH (World Health Organization-International Society of Hypertension) define hypertension as a persistent elevation of blood pressure greater than 140/90 mm Hg. (ayurvaid.com)
- The disease hypertension is an abnormality of Rakta Dhatu (blood) and is popularly known as Shonita Dusti (vitiated blood). (ayurvaid.com)
- Thus, when analyzing an electronic database containing information about patients monitored by general practitioners in Wisconsin (USA), such risk factors as high levels of triglycerides (TG), low levels of high density lipoprotein cholesterol (HDL), arterial hypertension , type 2 diabetes. (weight-loss-easy.com)
- It should be taken into account that, in addition to the direct atherogenic action of dyslipidemia, the high risk of cardiovascular diseases is determined by the frequent combination of lipid metabolism disorders with other components of the metabolic syndrome: carbohydrate metabolism disorders, increased proinflammatory and prothrombotic markers, arterial hypertension. (weight-loss-easy.com)
- He urged citizens who suffer from chronic diseases, such as hypertension and diabetes, to visit healthcare units and check their health status for free. (ahram.org.eg)
- Type 1 diabetes or diabetes secondary to a specific disease, prior bariatric surgery, mental impairment, drug or alcohol addiction, recent major vascular event, or portal hypertension. (acc.org)
- Trends in blood pressure, blood lipids, and smoking from 259 753 patients with hypertension in a Swedish primary care register: results from QregPV. (vgregion.se)
- In evaluating blood pressure in type 1 diabetes and overweight subjects, ABPM should be used since a reduced dipping can indicate incipient hypertension. (biomedcentral.com)
- Type 1 diabetes is associated with a higher cardiovascular morbidity and mortality rate and hypertension is one of the risk factors leading to increased incidence of vascular events diabetic subjects [ 3 ]. (biomedcentral.com)
- No association with hypertension was detected, however, systolic blood pressure (p = 0.002) was associated with fewer lesions. (kaiserpermanente.org)
- Prior to the surgery, about 44% of the patients suffered from hypertension, 24% had diabetes, and 44% hyperlipidemia. (medscape.com)
Metabolism4
- Early-onset diabetes patients had a longer diabetes duration, higher body mass index, and worse blood lipid metabolism profile. (cdc.gov)
- 7 Diabetes and perturbed glucose metabolism have been proven as risk factors for cognitive impairment. (dovepress.com)
- The lower carbohydrate and lipid metabolism content of the diabetes diet may benefit glucose tolerance control in people with diabetes. (healthcanal.com)
- They are mostly transported in a protein capsule, and the density of the lipids and type of protein determines the fate of the particle and its influence on metabolism. (patsnap.com)
Waist1
- For example, if you have a BMI outside the normal range, your health care provider might also look at skinfold thickness (a measure of body fat), waist size, evaluations of your diet and family health problems, blood sugar levels, and other factors to find out if your weight might pose a health risk. (cancer.org)
Cholesterol13
- People who are overweight or obese have a greater chance of developing several types of cancer -including colorectal cancer and breast cancer (for women past menopause)-as well as high blood pressure, high blood cholesterol or other lipid disorders, diabetes, heart disease, and stroke. (cancer.org)
- There are 2 major types of lipids in the blood: cholesterol and triglycerides. (who.int)
- Occupational health nurses can assist workers to be aware of their risk by measuring and providing culturally and linguistically appropriate education on blood pressure, BMI, cholesterol, and HbA1c. (cdc.gov)
- APOE can alter cholesterol homeostasis, lipid transport, Aβ deposition, and clearance in an isoform-dependent manner. (dovepress.com)
- Persons with diabetes should have regular health screenings to check for blood pressure, BMI, cholesterol, glucose, and triglycerides in order to decrease the risks associated with metabolic syndrome and CVD. (uncg.edu)
- The objective of the study was to test the hypothesis that levels of the various lipid components (total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides) are differentially associated with concentrations of total PCBs and total pesticides, and further that different congeners, congener groups and different pesticides do not have identical associations in serum samples obtained from Anniston residents in a cross-sectional study. (cdc.gov)
- Fasting serum samples were obtained from 575 residents of Anniston who were not on any lipid-lowering medication and were analyzed for 35 PCB congeners, nine chlorinated pesticides, total cholesterol, LDL and HDL cholesterol and triglyceride concentrations. (cdc.gov)
- Triglycerides (TGs) and cholesterol contribute most to disease, although all lipids are physiologically important. (msdmanuals.com)
- Changes in blood pressure and total or low density lipoprotein cholesterol concentrations were not significantly different. (bmj.com)
- Many studies conducted in recent decades demonstrate that a decrease in body weight against the background of calorie restriction and increased physical activity is accompanied by a decrease in triglyceride levels and an increase in HDL cholesterol levels. (weight-loss-easy.com)
- According to the meta-analysis of FASHO A., CG-ESHEOP D., 1992), with a decrease in body weight per 1 kg, the level of total cholesterol (total cholesterol) decreases by 0.05 mmol/l, the level of LDL cholesterol - by 0.02 mmol/l, and the level of TG - 0,015 mmol/l. (weight-loss-easy.com)
- MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomized placebo-controlled trial. (jamanetwork.com)
- Blood lipids are mainly fatty acids and cholesterol. (patsnap.com)
Serum4
- A total of 758 Anniston residents had multiple measurements of blood pressure, provided information on demographic factors, medications, smoking, and exercise and provided blood samples for determination of PCBs and total serum lipids. (cdc.gov)
- Linear regression analysis was used to determine the relationships between blood pressure and serum levels of the various contaminants after adjustment for age, body mass index (BMI), gender, race, smoking and exercise in 394 Anniston residents who were not on anti-hypertensive medication. (cdc.gov)
- Other than age total serum PCB concentration was the strongest determinant of blood pressure of the covariates studied. (cdc.gov)
- We investigated the association between diet and serum LPS activity in 668 individuals with type 1 diabetes in the FinnDiane Study. (nature.com)
Pressure25
- Gestational sleep deprivation is associated with higher offspring body mass index and blood pressure. (nih.gov)
- Body mass index (BMI), lipids, blood pressure, Hemoglobin A1c (HbA1c), and cardiorespiratory fitness (step test) were used to examine cardiovascular risk. (cdc.gov)
- Secondary prevention works through reducing risk factors associated with heart attack and stroke such as high blood sugar, lipids and blood pressure. (escardio.org)
- Her blood pressure today is 130/90 mm Hg. (medscape.com)
- How much of the effect of diabetes on vascular risk is due to the effect of diabetes on lipids and blood pressure? (bmj.com)
- Hazard ratios (HRs) for vascular disease were calculated using within-study regressions that were adjusted for age, sex, smoking, systolic blood pressure, and body-mass index. (bmj.com)
- Employees have made health gains including lower body mass index and blood pressure. (healthleadersmedia.com)
- The researchers assessed the association between incident diabetes and cumulative radiation exposure after adjusting for a wide range of potential confounders including age, body mass index, smoking, alcohol consumption, leisure-time physical activity, employment at the nuclear power plant, dyslipidemia (abnormally high levels of fats in the blood), and high blood pressure. (medicalxpress.com)
- The chlorinated pesticides showed little or no relationship to blood pressure. (cdc.gov)
- The associations were found over the full range of blood pressure as well as in those subjects whose blood pressure was in the normal range. (cdc.gov)
- The theme for World Health Day (WHD) 2013 is "high blood pressure. (ayurvaid.com)
- Diagnosis is made clinically by recording the Blood pressure in Sphygmomanometer. (ayurvaid.com)
- The initiative offers tests to measure blood pressure, random and cumulative blood sugar levels, blood lipids, kidney tests, and body mass index in 3,601 primary care units nationwide, said Abdel-Ghffar. (ahram.org.eg)
- Blood Pressure Lowering Trialists' Collaboration. (jamanetwork.com)
- Effects of different blood pressure lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomized trials. (jamanetwork.com)
- Systolic blood pressure was also nonsignificantly reduced by gastric banding. (acc.org)
- The aim of our observational cross-sectional study conducted in adolescents with type 1 diabetes, overweight subjects and healthy controls was to assess mean blood pressure parameters to identify subclinical cardiovascular risk. (biomedcentral.com)
- 0.001) blood pressure values. (biomedcentral.com)
- The aim of our observational cross-sectional study, performed in adolescents patients with type 1 diabetes since at least 3 years, overweight subjects and healthy controls aged between 13 and 21 years, was to assess mean blood pressure parameters, to identify subclinic cardiovascular risk of these patients. (biomedcentral.com)
- The use of drugs to lower glucose, lipid, and blood-pressure levels decreased significantly after both surgical procedures but increased in patients receiving medical therapy only. (nih.gov)
- After the surgery, 63% saw their blood pressure fall, 73% had an improvement in their diabetes, and 65% experienced improvements in lipids. (medscape.com)
- Lowering one's body mass index (BMI) to within the 'normal' range of 20 - 25kg/m2 can help to reduce blood pressure, blood lipids and the occurrence of a sedentary lifestyle. (dsm.com)
- In such cases, drugs, such as statins, are needed to treat elevated blood lipids, and other drugs can be used to treat high blood pressure or even an addiction to smoking. (dsm.com)
- To evaluate pleiotropy, we tested CAD loci for association with cardiovascular risk factors (lipid traits, blood pressure phenotypes, body mass index, diabetes, and smoking behavior), as well as with other diseases/traits through interrogation of currently available genome-wide association study catalogs. (ox.ac.uk)
- It's hypothesized that individuals diagnosed with diabetes at younger ages may exhibit more aggressive phenotypes characterized by higher body mass index, blood pressure, proatherogenic lipid levels, and faster deterioration in glycemic control, contributing to premature mortality. (medtigo.com)
Levels10
- Advanced age, long course of T2DM, elevated levels of FFA, UA, and Hcy are all risk factors of CHD in patients with type 2 diabetes. (hindawi.com)
- Fasting blood samples were obtained to determine the levels of glucose, insulin, lipids, and lipid particle size. (psychiatrist.com)
- Our findings suggest an increased risk of diabetes among nuclear emergency workers from low levels of radiation. (medicalxpress.com)
- Some studies have shown that subjects given Paleo diets, including those with type 2 diabetes, reduced their calorie intake, lowered their weight [3] , and improved their blood sugar and insulin levels. (healthcanal.com)
- Research [6] has found that following a low-carb diet improved blood sugars and Hemoglobin A1c levels in people with type 2 diabetes. (healthcanal.com)
- Paleo-healthy diets eliminate most low-fiber, refined carbohydrate sources, which may help people with diabetes control their blood sugar and insulin levels. (healthcanal.com)
- For this cross-sectional study, data were analyzed from randomly selected adults (n=774) who completed the Anniston Community Health Survey and underwent measurements of height, weight, fasting glucose, lipid and PCB levels and verification of medications. (cdc.gov)
- Additionally, elevated total PCB levels, specific congener groups, and dichlorodiphenyldichloroethylene (DDE) were associated with a doubling in the log risk of diabetes among women (p‹0.05) but not in men. (cdc.gov)
- Laparoscopic adjustable gastric banding would result in a higher incidence of diabetes remission and reduction in glycated hemoglobin levels in obese patients, compared with conventional approaches to weight loss and diabetes control. (acc.org)
- Hyperlipidemia is the presence of elevated or abnormal levels of lipids and/or lipoproteins in the blood, and is a major risk factor for cardiovascular disease. (patsnap.com)
Gestational diabetes1
- We tested for mediation by birthweight, gestational age, and gestational diabetes. (nih.gov)
Lipoprotein1
- Pathway defects in lipoprotein synthesis, processing, and clearance can lead to accumulation of atherogenic lipids in plasma and endothelium. (msdmanuals.com)
Type51
- NAFLD: Cause or Consequence of Type 2 Diabetes? (medscape.com)
- Nonalcoholic Fatty Liver Disease: Cause or Consequence of Type 2 Diabetes? (medscape.com)
- Growing epidemiological evidence suggests that nonalcoholic fatty liver disease (NAFLD) is an early predictor of and determinant for the development of type 2 diabetes and other features of the metabolic syndrome. (medscape.com)
- This finding may have important clinical implications for the diagnosis, prevention and treatment of type 2 diabetes and its chronic complications. (medscape.com)
- Furthermore, genetic studies suggest that excess hepatic fat is associated with progressive liver disease, but does not always increase the risk of incident type 2 diabetes. (medscape.com)
- Here, we will briefly review the epidemiological, pathophysiological and molecular evidence linking NAFLD to the development of type 2 diabetes. (medscape.com)
- We will also discuss some recent genetic and therapeutic advances that seem to challenge a causal role of NAFLD in the pathogenesis type 2 diabetes, and propose a working hypothesis to explain this apparent conundrum. (medscape.com)
- The impact of excess weight on cardiovascular disease risk in type 1 diabetes patients is unclear. (nih.gov)
- The sample includes youth with type 1 diabetes (N = 136, baseline age = 12.3 ± 2.5y, glycated hemoglobin = 8.1 ± 1.1%) participating in an 18-month behavioral nutrition intervention trial. (nih.gov)
- Biological risk factors may explain the racial health disparity for developing type 2 diabetes. (nih.gov)
- In type 2 diabetes, your body doesn't make enough insulin or doesn't use insulin well. (nih.gov)
- You can develop type 2 diabetes at any age. (nih.gov)
- However, type 2 diabetes occurs most often in middle-aged and older people. (nih.gov)
- You're more likely to develop type 2 diabetes if you are 45 or older, have a family history of diabetes, or are overweight or obese. (nih.gov)
- In the U.S., black adults are nearly twice as likely as white adults to develop type 2 diabetes. (nih.gov)
- Compared with the type 2 diabetes of typical onset in middle age or older, type 2 diabetes with early age of onset has a higher risk of diabetes-related complications. (cdc.gov)
- We enrolled 1,111 type 2 diabetes patients with DKD in this study. (cdc.gov)
- Duration of diabetes has been considered a strong factor in the development of vascular complications of type 2 diabetes (6). (cdc.gov)
- This study investigated the patterns and determinants of lipid disorders among a group of 250 type 2 adult diabetic patients and 60 age- and sex-matched healthy controls in Sudan. (who.int)
- Cette étude a porté sur les caractéristiques et les déterminants des troubles lipidiques dans un groupe de 250 adultes atteints de diabète de type 2 et dans un groupe témoin de 60 sujets sains du même âge et du même sexe au Soudan. (who.int)
- These risk factors are referred to collectively as metabolic syndrome, and they can lead to cardiovascular disease and type 2 diabetes. (nih.gov)
- Methods: The study adopted a descriptive, cross-sectional design and obtained data from 372 individuals with type 2 diabetes attending six selected primary healthcare centres (PHCs) in two EC districts. (researchgate.net)
- The American Diabetes Association (ADA) recommends individualized MNT, preferably provided by a registered dietitian, for all people with type 1 or type 2 diabetes. (medscape.com)
- [ 2 ] MNT delivered by a registered dietitian is associated with hemoglobin A 1c (HbA 1c ) decreases of 0.3-1% for people with type 1 diabetes and 0.5-2% for people with type 2 diabetes. (medscape.com)
- [ 7 ] The ADA guidelines find a variety of eating patterns are acceptable for the management of type 2 diabetes and prediabetes including Mediterranean, DASH, and plant-based diets. (medscape.com)
- A 53-year-old Asian American woman in the United States was recently diagnosed with type 2 diabetes. (medscape.com)
- Menstruation Linked to Underdiagnosis of Type 2 Diabetes? (medscape.com)
- What Updates Are in the 2023 American Association of Clinical Endocrinology Type 2 Diabetes Algorithm? (medscape.com)
- For example, although a tax-exempt hospital might have provided free diabetes medications and medical care for diabetic patients without insurance, if the hospital did not also address the underlying causes of type 2 diabetes (e.g., access to healthy foods and safe locations for physical activity), diabetes-related outcomes among these patients might not have improved substantially or might have worsened. (cdc.gov)
- minorities are disproportionately affected, and are at risk for type II diabetes, metabolic syndrome, and cardiovascular disease. (confex.com)
- The increasing prevalence of type 2 diabetes and suboptimal glycaemic control in Kuwait requires novel, wide-reaching, low-cost interventions to motivate and mobilise individuals towards more effective self-management. (biomedcentral.com)
- This is a two-arm parallel single-blind randomised controlled trial of 572 individuals with type 2 diabetes in Kuwait. (biomedcentral.com)
- We will develop a culturally appropriate database of text messages supporting positive lifestyle changes in type 2 diabetes. (biomedcentral.com)
- Individuals aged 18-75 years with established type 2 diabetes who are fluent in Arabic or English and officially resident in Kuwait will be identified via screening of hospital diabetes clinic and primary care practices and invited to participate. (biomedcentral.com)
- the second highest prevalence of type 2 diabetes reported in all high-income countries by the World Health Organisation [ 3 ]. (biomedcentral.com)
- The increased prevalence of type 2 diabetes in countries such as Kuwait has been attributed in part to significant socioeconomic change, which can enable a more sedentary lifestyle and increased intake of high calorie food [ 4 ]. (biomedcentral.com)
- Treatment algorithms define lines of glucose lowering medications (GLM) for the management of type 2 diabetes (T2D), but whether therapeutic trajectories are associated with major adverse cardiovascular events (MACE) is unclear. (biomedcentral.com)
- Type 2 diabetes (T2D) is a chronic progressive disorder requiring iterated adjustments of pharmacotherapy. (biomedcentral.com)
- Among obese patients with BMI between 30 and 40 and type 2 diabetes diagnosed within the preceding 2 years, laparoscopic adjustable gastric banding resulted in a significant increase in the proportion of patients with remission of diabetes. (acc.org)
- This is a remarkable trial that documents profound health benefits among obese patients and type 2 diabetes 2 years after laparoscopic gastric banding. (acc.org)
- Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial. (acc.org)
- The study included adolescents patients with type 1 diabetes followed in our Pediatric Department in University of Catania between January 2011 and 2013. (biomedcentral.com)
- The study included adolescent patients with type 1 diabetes followed in our Cardiology and Endocrinology Clinic of Pediatric Department in University of Catania in Italy between January 2011 and 2013. (biomedcentral.com)
- In this randomized, nonblinded, single-center trial, we evaluated the efficacy of intensive medical therapy alone versus medical therapy plus Roux-en-Y gastric bypass or sleeve gastrectomy in 150 obese patients with uncontrolled type 2 diabetes. (nih.gov)
- In obese patients with uncontrolled type 2 diabetes, 12 months of medical therapy plus bariatric surgery achieved glycemic control in significantly more patients than medical therapy alone. (nih.gov)
- As a result, individuals living on this diet are at greater risk of heart attack, stroke, type 2 diabetes and even death 4 , with dietary factors estimated to be associated with a substantial proportion of mortalities 5 . (dsm.com)
- The study also emphasized the importance of early detection through screening and intensive glucose management as potential avenues for mitigating the long-term complications associated with type 2 diabetes. (medtigo.com)
- Type 2 diabetes is associated with altered immune and hemostatic responses. (ashpublications.org)
- These data suggest that type 2 diabetes patients may be especially vulnerable to prothrombotic events during inflammatory states. (ashpublications.org)
- Type 2 diabetes is associated with an increased risk for thrombotic complications. (ashpublications.org)
- This study showed that glucomannan noodles as a staple food can contribute to metabolic syndrome in adults predisposed to type 2 diabetes. (tmu.edu.tw)
Metabolic2
- The metabolic switches in the pancreas govern the way dietary fat and sugar intake is handled and how energy reserves are stored in body fat or the liver. (nih.gov)
- ABSTRACT Objectives: Using the PRECEDE-PROCEED model, this study examined the presence of metabolic syndrome and modifiable cardiovascular disease (CVD) risk factors associated with metabolic syndrome among Chinese adults with diabetes living in Beijing, China. (uncg.edu)
Obese patients1
- The goal of this trial was to evaluate laparoscopic adjustable gastric banding compared with conventional approaches to weight loss and diabetes control in obese patients with recently diagnosed diabetes. (acc.org)
Hyperlipidemia1
- No significant association with lesion count was observed for diabetes, hyperlipidemia, smoking status or for related quantitative traits. (kaiserpermanente.org)
Myocardial infarction2
- For example, to what extent is diabetes associated with fatal vs non-fatal myocardial infarction? (bmj.com)
- Notably, the study found that the most substantial associations with earlier age at diabetes diagnosis were related to vascular conditions, including myocardial infarction and stroke, as well as other non-neoplastic causes of death, such as respiratory, neurological, infectious diseases, and external causes. (medtigo.com)
Renal3
- It is unclear whether the early age of diabetes diagnosis would affect the development of end-stage renal disease (ESRD) in patients with diabetic kidney disease (DKD) who are at higher risk of ESRD. (cdc.gov)
- Low-carbohydrate and low-fat diets used to achieve initial weight loss are effective for the short term (approximately 1 y) and need monitoring with a lipid profile and renal function tests. (medscape.com)
- Adjusted HRs with diabetes are shown in figure 1, and did not change appreciably after further adjustment for lipid, inflammatory, or renal markers. (bmj.com)
Uric acid1
- People who live to 100 years have lower measures of creatinine, glucose and uric acid in their blood compared to those with a comparatively shorter lifespan, researchers say. (medicaldaily.com)
Disorders1
- It turned out that the presence of at least two of these disorders increased by 5 times the probability that the patient's body mass index (BMI) would be higher than 27. (weight-loss-easy.com)
Baseline1
- Results The meta-analysis included 11 studies with 796 individuals (range of mean body mass index at baseline 30-52). (bmj.com)
Complications4
- Prevention strategies for diabetic complications should emphasize closer attention to patients with DKD and early-onset diabetes. (cdc.gov)
- Diabetes is a chronic illness that requires a holistic approach to care to prevent both acute and long-term complications. (medscape.com)
- Nutritional management for diabetic patients has been evolving for more than 100 years as the pathophysiological basis of complications due to diabetes becomes more explicit. (medscape.com)
- Complications of diabetes are well understood. (biomedcentral.com)
Risk29
- This study examined associations of BMI and body composition with cardiovascular risk factors in youth followed prospectively for 18 months. (nih.gov)
- A study found that biological risk factors-including weight and fat around the abdomen-are primarily responsible for higher rates of diabetes for black Americans compared with white Americans. (nih.gov)
- The study suggests that making positive changes in known risk factors, like losing excess weight, can help reduce the racial health disparity for developing diabetes. (nih.gov)
- The researchers collected information from participants about different risk factors for diabetes over 30 years. (nih.gov)
- The researchers used statistical analyses to determine how biological, neighborhood, psychosocial, socioeconomic, and behavioral risk factors contributed to rates of diabetes. (nih.gov)
- Our efforts to control the traditional risk factors can work to reduce the disparities we observe in diabetes incidence. (nih.gov)
- Early-onset diabetes is an independent risk factor for ESRD in patients with DKD. (cdc.gov)
- To learn more about BMI and how extra body weight can affect your risk of cancer, see Body Weight and Cancer Risk . (cancer.org)
- T2DM patients with the above risk factors should be vigilant and pay attention to monitoring the related indexes of coronary heart disease to avoid the occurrence of serious cardiovascular disease. (hindawi.com)
- Diabetes and CHD are not only single endocrine diseases and cardiovascular diseases but also inseparable and permeate each other, so we should pay attention to the intersection of disciplines, strengthen multilevel prevention, and comprehensively control the cardiovascular risk factors of patients with diabetes. (hindawi.com)
- The association between dietary fatty acids and cardiovascular disease (CVD) risk has been extensively studied, and predictive equations on their blood lipid effects have been validated [ 2 ]. (springer.com)
- This study was a meta-analysis of the individual records of diabetes, fasting blood glucose concentration, and other risk factors in people without vascular disease in the Emerging Risk Factor Collaboration. (bmj.com)
- However, in people without diabetes, information about fasting blood glucose concentration or impaired fasting glucose status did not significantly improve metrics of vascular disease prediction when added to information about several conventional risk factors. (bmj.com)
- In this large meta-analysis, diabetes was found to confer about a two-fold excess risk for a wide range of vascular diseases, independently from other risk factors. (bmj.com)
- New research presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD), Hamburg (2-6 Oct), suggests that exposure to low doses of radiation may contribute to an increased risk of diabetes. (medicalxpress.com)
- To find out more, researchers examined the association between low-dose radiation exposure and risk of diabetes in 5,326 male emergency workers (average age 46 years) taking part in the NEWS study. (medicalxpress.com)
- The analysis found that compared with the lowest cumulative low-dose radiation exposure (0-4 millisieverts [mSv]), the risk of developing diabetes was 6% higher for workers exposed to 5-9 mSv, and 47% and 33% greater for those exposed to 10-19 mSv and 20-49 mSv, respectively. (medicalxpress.com)
- He adds, "Ongoing follow-up of NEWS participants will provide an even clearer picture of diabetes risk at low radiation doses. (medicalxpress.com)
- As more diabetes cases emerge within our study group, our expanded dataset will enable more robust analyses, allowing researchers to better assess the link between radiation exposure and diabetes risk. (medicalxpress.com)
- The authors note that the findings show observational associations rather than cause and effect and point to several limitations, including the absence of data on diabetes types, potential residual confounding from unaccounted factors or measurement inaccuracies affecting the diabetes-risk and radiation-exposure link. (medicalxpress.com)
- Odds ratios (OR) and 95% confidence intervals were calculated to assess the relationships between PCBs and diabetes, adjusting for diabetes risk factors. (cdc.gov)
- Eligibility criteria Eligible studies were randomised controlled trials with ≥6 months of follow-up that included individuals with a body mass index ≥30, compared current bariatric surgery techniques with non-surgical treatment, and reported on body weight, cardiovascular risk factors, quality of life, or adverse events. (bmj.com)
- Prospective associations of platelet size (an index of platelet maturity and activity) with lung cancer risk are unclear. (biomedcentral.com)
- The magnitude of effect on cardiovascular risk factors is impressive, and to date no pharmacological therapy for weight management or diabetes has shown a comparable effect over these short time periods," say Dr Amanda Vest (Cleveland Clinic, OH) and colleagues in their paper published online October 167, 2012 in Heart . (medscape.com)
- The results of the study demonstrated a compelling dose-response relationship, indicating that earlier age at diabetes diagnosis was associated with a significantly higher risk of all-cause mortality. (medtigo.com)
- The observed higher hazard ratios for mortality with earlier diabetes diagnosis suggest that the relative impact of diabetes is most pronounced at ages when the underlying mortality risk in the general population is lowest. (medtigo.com)
- This aligns with previous research on cardiovascular risk factors and underscores the significance of addressing diabetes among younger populations. (medtigo.com)
- In conclusion, the study's findings emphasize the substantial impact of age at diabetes diagnosis on life expectancy, underscoring the need for proactive measures to prevent or delay the onset of diabetes among younger individuals and intensify the treatment of risk factors in this population. (medtigo.com)
- 2 Apart from the accelerated development of atherosclerosis in patients with diabetes, these patients were also found to have an increased risk of thrombotic events, explained by an increased procoagulant activity combined with a decreased fibrinolytic capacity. (ashpublications.org)
Inflammatory1
- The plaques contain lipids, inflammatory cells, smooth muscle. (msdmanuals.com)
Fats2
- Lipids are fats that are either absorbed from food or synthesized by the liver. (msdmanuals.com)
- Blood lipids (or blood fats) are lipids in the blood, either free or bound to other molecules. (patsnap.com)
Favorable2
- Low-carbohydrate diets (20-120 g/d) carry the additional benefit of a favorable lipid profile as compared with low-fat diets. (medscape.com)
- Moreover, these favorable changes in the lipid spectrum of blood are observed even with a moderate decrease in body weight - 5-10% of the original. (weight-loss-easy.com)
Biomarkers1
- Study participants underwent regular health examinations involving more than 70 components, including blood sugar , lipids, urine tests, inflammation biomarkers, thyroid function tests, and eye examinations. (medicalxpress.com)
Homeostasis1
- Chronic disease diagnoses plus blood markers of liver function, glucose homeostasis, inflammation, and lipid changes. (flutrackers.com)
Overweight1
- Hispanic children aged 5-14 years (goal N=200) who were overweight (body mass index [BMI] 85th-94th percentile for age and gender) or obese (BMI &ge95th percentile) and a parent (goal N=200) were recruited from a pediatric clinic, and randomized to standard care (SC) or an educational intervention (EI). (confex.com)
Profile2
- The rest of lipid profile, fasting blood glucose, insulin, and HOMA-IR of the subjects did not show any significant difference. (tmu.edu.tw)
- The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile. (patsnap.com)
Concentration3
- The concentration of brain diabetes educator course ontario neurotrophic factor BDNF increased, and the expression of capillary glucose transporter 1 did the same in the hippocampus. (barkonyhakellek.hu)
- Glucomannan is a water-soluble dietary fiber derived from the root of Amorphophallus konjac that can improve blood sugar, blood fat concentration, and weight management, and has other health benefits. (tmu.edu.tw)
- The concentration of blood lipids depends on intake and excretion from the intestine, and uptake and secretion from cells. (patsnap.com)
Signaling pathway1
- 2. Overexpression of LPCAT1 enhances endometrial cancer stemness and metastasis by changing lipid components and activating the TGF/β-Smad2/3 signaling pathway. (nih.gov)
Physical1
- Secondary outcomes will include changes in physical activity, fasting lipids and quality of life in both study arms. (biomedcentral.com)
Statins1
- Certain medicines are also more commonly associated with adverse events, including those that are prescribed most often (e.g. paracetamol, NSAIDs, ACE inhibitors, statins) and those with a narrow therapeutic index (e.g. warfarin, lithium and digoxin). (bpac.org.nz)
Lipoproteins2
- All lipids are hydrophobic and mostly insoluble in blood, so they require transport within lipoproteins. (msdmanuals.com)
- Lipoproteins circulate through the blood continuously until the TGs they contain are taken up by peripheral tissues or the lipoproteins themselves are cleared by the liver. (msdmanuals.com)
Diagnosis6
- We used the age at diabetes diagnosis of younger than 40 years to define early-onset diabetes and 40 years or older to define late-onset diabetes. (cdc.gov)
- Between 2012 and 2021, 392 participants developed diabetes-defined as a fast plasma glucose level of at least 126 mg/dL, an HbA1c level of at least 6.5%, or self-reported diagnosis of diabetes. (medicalxpress.com)
- The Lancet published a groundbreaking study that examined the association between the age of diabetes diagnosis and its impact on life expectancy. (medtigo.com)
- This study aimed to provide a comprehensive analysis of how age at diabetes diagnosis relates to all-cause mortality, cause-specific mortality, and reductions in life expectancy, focusing primarily on high-income countries. (medtigo.com)
- While the study offers crucial insights into the relationship between age at diabetes diagnosis and life expectancy, it also acknowledges certain limitations, including variations in how diabetes was defined across contributing studies and the absence of information regarding the pathophysiological subtype of diabetes. (medtigo.com)
- This research provides valuable insights into the long-term consequences of early diabetes diagnosis and highlights the importance of public health initiatives and clinical interventions to address this pressing global health issue. (medtigo.com)
Significantly1
- The study found that the chance of developed diabetes was significantly higher for black adults than for white adults (about 66 more cases of diabetes per 1,000 people). (nih.gov)
High3
- Diabetes is a disease that occurs when your blood glucose (also called blood sugar) is too high. (nih.gov)
- The potential of mobile phones in improving diabetes self-care in settings with a high prevalence of diabetes and widespread mobile phone usage has face validity. (biomedcentral.com)
- High-income countries experience a stark reduction in life expectancy for individuals diagnosed with diabetes at younger ages, according to a comprehensive study spanning over 19 nations and more than 23 million person-years of data. (medtigo.com)
Chronic1
- Its important role in preventing chronic diseases such as CVDs, diabetes, cancer and musculoskeletal diseases has been proven [ 16 ]. (biomedcentral.com)
Patients6
- Some studies have found that a subset of patients with longer diabetes duration are characterized by an earlier age of diabetes onset. (cdc.gov)
- The mean duration of diabetes was 9.4 years and 46.0% of patients had poor glycaemic control. (who.int)
- L'ancienneté moyenne du diabète était de 9,4 ans et chez 46,0 % des patients, la glycémie n'était pas bien contrôlée. (who.int)
- Proportion of patients with remission from diabetes. (acc.org)
- After a 3-month run-in period to optimize diabetes management by involvement of dieticians, general physicians, and endocrinologists, patients were randomized to laparoscopic adjustable gastric banding (n = 30) and conventional diabetes management (n = 30). (acc.org)
- The mean age of the patients was 15.4 ± 2.3 (13-21) years and duration of diabetes was 8 ± 3.2 (3-17) years. (biomedcentral.com)
Results3
- The two data of blood lipid were obtained from UK Biobank (UKBB) and Global Lipid Genetics Consortium Results (GLGC). (nih.gov)
- 60 (16.1%) had eGFR results, while only 33 (8.9%) had documented lipid results. (researchgate.net)
- Incidence of erectile dysfunction in men 40 to 69 years old: longitudinal results from the Massachusetts Male Aging Study. (jamanetwork.com)