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  • Lung
  • Providing global leadership in research, training, and education to prevent and treat heart, lung, blood and sleep disorders. (nih.gov)
  • They found that the CD276 protein was overexpressed in tumor-associated blood vessels from colon, lung, breast, esophageal and bladder cancers. (nih.gov)
  • vessels
  • ACE inhibitors help the body produce less angiotensin, which helps the blood vessels relax and open up, which, in turn, lowers blood pressure. (heart.org)
  • A team of researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), has uncovered a set of genes that are turned on, or expressed, at high levels only in the blood vessels that feed tumors in mice and humans. (nih.gov)
  • These genes, and the proteins they encode, are important new potential targets for novel drugs that could selectively cut off a tumor's blood supply without affecting the blood vessels of healthy tissues, overcoming one of the major concerns of current anticancer therapies targeted at blood vessel growth. (nih.gov)
  • The growth of blood vessels, a process known as angiogenesis, is a normal process in the body that is essential for organ growth and repair. (nih.gov)
  • St. Croix and his colleagues focused on endothelial cells, which line the inner surface of blood vessels and are critical for new vascular growth. (nih.gov)
  • The researchers chose to analyze endothelial cells derived from mouse liver, because the liver can be induced to sprout new blood vessels when regenerating itself following partial surgical removal. (nih.gov)
  • In addition, the protein was also found to be frequently overexpressed by the tumor cells themselves, indicating that a suitable inhibitory molecule might be able to deliver a double blow -- one to the tumor cells themselves and the other to the blood vessels that feed them. (nih.gov)
  • These studies demonstrate that CD276 is overexpressed in the blood vessels of a variety of human cancers," says St. Croix. (nih.gov)
  • Therefore, it may be an important target for the development of new drugs that can selectively home in on blood vessels associated with disease. (nih.gov)
  • After determining that a patient has high blood pressure, the physician will look for possible causes and determine any effects it may have on key organs, such as the heart, kidneys, brain and blood vessels. (cedars-sinai.edu)
  • Blood is circulated around the body through blood vessels by the pumping action of the heart. (wikipedia.org)
  • kidneys
  • For example, a urinary tract infection may spread from the bladder and/or kidneys into the blood and then be carried throughout the body, infecting other organs and causing a serious and sometimes life-threatening systemic infection. (labtestsonline.org)
  • vessel
  • In many diseases, including most forms of cancer, this carefully regulated process becomes imbalanced, and normal blood vessel growth is redirected toward supplying nutrients and oxygen to feed diseased tissue, destroy normal tissues, and in the case of cancer, allow tumor cells to escape and travel to distant sites in the body. (nih.gov)
  • Researchers have tried to stop disease-related angiogenesis by identifying the molecules that stimulate blood vessel and developing new drugs to block their action. (nih.gov)
  • However, blocking angiogenesis requires a delicate balance between tumor and normal cells as most angiogenesis-related molecules are also critical for normal blood vessel growth in the body - for example, during menstruation, pregnancy, or tissue repair. (nih.gov)
  • The red blood cells (together with endothelial vessel cells and other cells) are also marked by glycoproteins that define the different blood types. (wikipedia.org)
  • symptoms
  • High blood pressure usually has no symptoms, but it can cause serious problems such as stroke , heart failure , heart attack and kidney failure . (medlineplus.gov)
  • They may include blood tests other lab tests to look for extra protein in the urine as well as other symptoms. (medlineplus.gov)
  • High blood pressure is often referred to as a "silent killer," due in large part to the absence of high blood pressure symptoms . (draxe.com)
  • Unlike general high blood pressure, hypertensive crises often appear with symptoms, such as severe headache, shortness of breath, nosebleeds, severe anxiety, and even loss of consciousness or heart attack (and several other extremely dangerous conditions) when it isn't treated quickly enough. (draxe.com)
  • If during the transfusion you have symptoms of shortness of breath , itching , fever or chills or just not feeling well, alert the person transfusing the blood immediately. (medicinenet.com)
  • Knot
  • A blood knot (barrel knot) is most usefully employed for joining sections of monofilament nylon line while maintaining a high portion of the line's inherent strength. (wikipedia.org)
  • The principal drawback to the blood knot is the dexterity required to tie it. (wikipedia.org)
  • Blood knot" may refer to, "a double overhand knot tied in a cat-o'-nine-tails. (wikipedia.org)
  • The barrel knot, called blood knot by Keith Rollo, is the best bend there is for small, stiff or slippery line. (wikipedia.org)
  • The Ashley Book of Knots A half blood knot (also clinch knot) is a knot that is used for securing a fishing line to a fishing lure, snap or swivel. (wikipedia.org)
  • When two half blood knots are used to join two lines they are considered as one knot and called a blood knot. (wikipedia.org)
  • A half blood knot is one of the strongest knots for tying a medium-size hook to a medium-size line such as hooksize 4 to 4/0 onto line size 6 lb to 30 lb. (wikipedia.org)
  • In tying the blood knot, the two lines to be joined are overlapped for 6-8 cm with the short ends of the two lines in opposite directions. (wikipedia.org)
  • Video instructions on how to tie a half blood knot Video instructions for tying a Blood Knot Grog. (wikipedia.org)
  • Blood Knot is an early play by South African playwright, actor, and director Athol Fugard. (wikipedia.org)
  • Lucille Lortel produced The Blood Knot, starring J.D. Cannon as Morris and James Earl Jones as Zachariah, at the Cricket Theatre, Off Broadway, in New York City, in 1964, "launch[ing]" Fugard's "American career. (wikipedia.org)
  • Fugard was pleased with the results: Back in S'Kop after five weeks in London for BBC TV production of The Blood Knot. (wikipedia.org)
  • In Time magazine, the same performance was reviewed by Pulitzer Prize-winning critic William A. Henry III, who notices the long collaboration between the two actors, Fugard and Mokae: "The actors' blood knot of decades of fraternal friendship has only ripened their truth onstage. (wikipedia.org)
  • tissues
  • In animals with lungs, arterial blood carries oxygen from inhaled air to the tissues of the body, and venous blood carries carbon dioxide, a waste product of metabolism produced by cells, from the tissues to the lungs to be exhaled. (wikipedia.org)
  • cells
  • A patient suffering from an iron deficiency or anemia may receive red blood cells to increase their hemoglobin and iron levels, improving the amount of oxygen in the body. (redcrossblood.org)
  • HELLP syndrome, which happens when a woman with preeclampsia or eclampsia has damage to the liver and blood cells. (medlineplus.gov)
  • The exact cause of myelofibrosis is not known, but it has been linked to the JAK2 gene, which control the production of blood cells. (eurekalert.org)
  • This is usually done as a lifesaving maneuver to replace blood cells or blood products lost through severe bleeding, during surgery when blood loss occurs or to increase the blood count in an anemic patient. (medicinenet.com)
  • Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells. (wikipedia.org)
  • In vertebrates, it is composed of blood cells suspended in blood plasma. (wikipedia.org)
  • Plasma, which constitutes 55% of blood fluid, is mostly water (92% by volume), and contains dissipated proteins, glucose, mineral ions, hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and blood cells themselves. (wikipedia.org)
  • The most abundant cells in vertebrate blood are red blood cells. (wikipedia.org)
  • Jawed vertebrates have an adaptive immune system, based largely on white blood cells. (wikipedia.org)
  • White blood cells help to resist infections and parasites. (wikipedia.org)
  • The average adult has a blood volume of roughly 5 litres (11 US pt), which is composed of plasma and several kinds of cells. (wikipedia.org)
  • Whole blood (plasma and cells) exhibits non-Newtonian fluid dynamics. (wikipedia.org)
  • Right tube: Freshly drawn blood One microliter of blood contains: 4.7 to 6.1 million (male), 4.2 to 5.4 million (female) erythrocytes: Red blood cells contain the blood's hemoglobin and distribute oxygen. (wikipedia.org)
  • Mature red blood cells lack a nucleus and organelles in mammals. (wikipedia.org)
  • The combined surface area of all red blood cells of the human body would be roughly 2,000 times as great as the body's exterior surface. (wikipedia.org)
  • coagulation
  • Serum includes all proteins not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances (e.g., drugs and microorganisms). (wikipedia.org)
  • infections
  • Anyone with a weakened immune system due to an underlying disease, such as leukemia or HIV/AIDS , or due to immunosuppressive drugs such as those given for chemotherapy is at a higher risk for blood infections as their immune system is less capable of killing the microorganisms that occasionally enter the blood. (labtestsonline.org)
  • immune system
  • A blood infection typically originates from some other specific site within the body, spreading from that site when a person has a severe infection and/or the immune system cannot confine it to its source. (labtestsonline.org)
  • high
  • Prehypertension means you may end up with high blood pressure, unless you take steps to prevent it. (medlineplus.gov)
  • You can control high blood pressure through healthy lifestyle habits such as exercise and the DASH diet and taking medicines , if needed. (medlineplus.gov)
  • Anxiety: A Cause of High Blood Pressure? (medlineplus.gov)
  • High Blood Pressure and Cold Remedies: Which Are Safe? (medlineplus.gov)
  • Stress and High Blood Pressure: What's the Connection? (medlineplus.gov)
  • There are a variety of classes of high blood pressure medications and they include a number of different drugs. (heart.org)
  • If you already have high blood pressure, eating more whole-grain foods might help lower your blood pressure. (mayoclinic.org)
  • The American Heart Association recommends home monitoring for all people with high blood pressure to help the healthcare provider determine whether treatments are working. (heart.org)
  • Individuals starting high blood pressure treatment to determine its effectiveness. (heart.org)
  • People requiring closer monitoring, especially individuals with risk factors for high blood pressure and/or conditions related to high blood pressure. (heart.org)
  • More than 70 million Americans have high blood pressure, and a third of those with the condition are unaware of it. (cedars-sinai.edu)
  • Very high blood pressure can be a life-threatening emergency. (cedars-sinai.edu)
  • In most cases, the causes of high blood pressure are not known. (cedars-sinai.edu)
  • The risk of high blood pressure is greater for those who are smokers, older than 75, overweight, sedentary or under stress. (cedars-sinai.edu)
  • High blood pressure is often discovered during a routine visit to the doctor or when another illness strikes. (cedars-sinai.edu)
  • If an underlying disease or condition has been identified as the cause, treatment of high blood pressure will focus on that condition. (cedars-sinai.edu)
  • But it does raise your risk of high blood pressure in the future. (medlineplus.gov)
  • The signs may include protein in the urine and very high blood pressure. (medlineplus.gov)
  • If your blood pressure reading is high (140/90 or higher), especially after the 20th week of pregnancy, your provider will likely want to run some tests. (medlineplus.gov)
  • 1 ) One of the most common conditions leading to heart disease and stroke (the No. 2 killer) is the all-too familiar issue of high blood pressure. (draxe.com)
  • 2 ) The good news is that high blood pressure can usually be reversed naturally, specifically through lifestyle changes and consuming foods that lower blood pressure. (draxe.com)
  • To me, that sounds pretty undesirable for something you can easily correct with a high blood pressure diet and lifestyle changes. (draxe.com)
  • The causes of high blood pressure can be complex but are generally related to lifestyle and diet. (draxe.com)
  • For example, people who eat high-sodium diets are at a much more elevated risk of high blood pressure. (draxe.com)
  • Most people don't know they have high blood pressure until they have been diagnosed by a health care practitioner. (draxe.com)
  • If you're at risk for high blood pressure or have already started experiencing high levels, implementing natural ways to lower blood pressure and eating these foods that lower blood pressure is a great place to start. (draxe.com)
  • Michael Fury (Chakiris) arrives in Los Angeles to investigate a series of mysterious high-profile murders where the victims have been completely drained of blood. (wikipedia.org)
  • Blood & Chocolate was recorded in a single large room at high volume, with the band listening to each other on monitor speakers and playing at stage volume, an unusual practice in the studio for its time. (wikipedia.org)
  • Blood meal is a dry, inert powder made from blood used as a high-nitrogen organic fertilizer and a high protein animal feed. (wikipedia.org)
  • Both boys were found to have high levels of cyanide in their blood in addition to gunshot wounds to the head. (wikipedia.org)
  • body's
  • Septicemia refers to an infection of the blood while sepsis is the body's serious, overwhelming, and sometimes life-threatening response to infection. (labtestsonline.org)
  • If these approaches are not effective, the patient may need to take daily medications to keep blood pressure readings in the normal range and prevent damage to the body's organs. (cedars-sinai.edu)
  • fibrinogen
  • In terms of anatomy and histology, blood is considered a specialized form of connective tissue, given its origin in the bones and the presence of potential molecular fibers in the form of fibrinogen. (wikipedia.org)
  • Anti-coagulated blood yields plasma containing fibrinogen and clotting factors. (wikipedia.org)
  • Coagulated blood (clotted blood) yields serum without fibrinogen, although some clotting factors remain. (wikipedia.org)
  • Pressure
  • Your blood pressure is highest when your heart beats, pumping the blood. (medlineplus.gov)
  • When your heart is at rest, between beats, your blood pressure falls. (medlineplus.gov)
  • Your blood pressure reading uses these two numbers. (medlineplus.gov)
  • Blood Pressure: Does It Have a Daily Pattern? (medlineplus.gov)
  • Blood Pressure: Is It Affected by Cold Weather? (medlineplus.gov)
  • Weightlifting: Bad for Your Blood Pressure? (medlineplus.gov)
  • Wrist Blood Pressure Monitors: Are They Accurate? (medlineplus.gov)
  • In the widget below, you will find an overview of the classes of blood pressure medication. (heart.org)
  • Beta-blockers reduce the heart rate, the heart's workload and the heart's output of blood, which lowers blood pressure. (heart.org)
  • Can whole-grain foods lower blood pressure? (mayoclinic.org)
  • Effects of increased consumption of whole-grain foods on blood pressure and other cardiovascular risk markers in healthy middle-aged persons: A randomized controlled trial. (mayoclinic.org)
  • Your guide to lowering blood pressure with DASH. (mayoclinic.org)
  • Don't smoke, drink caffeinated beverages or exercise within 30 minutes before measuring your blood pressure. (heart.org)
  • A doctor should also evaluate any unusually low blood pressure readings . (heart.org)
  • If you get a reading that is slightly or moderately higher than normal, take your blood pressure a few more times and consult your healthcare professional to verify if there' s a health concern or whether there may be any issues with your monitor. (heart.org)
  • If your blood pressure readings suddenly exceed 180/120 mm Hg, wait five minutes and test again. (heart.org)
  • If your blood pressure is higher than 180/120 mm Hg and you are experiencing signs of possible organ damage such as chest pain, shortness of breath, back pain, numbness/weakness, change in vision, difficulty speaking, do not wait to see if your pressure comes down on its own. (heart.org)
  • Home monitoring (self-measured blood pressure) is not a substitute for regular visits to your physician. (heart.org)
  • If you have been prescribed medication to lower your blood pressure, don't stop taking your medication without consulting your doctor, even if your blood pressure readings are in the normal range during home monitoring. (heart.org)
  • When selecting a blood pressure monitor for a senior, pregnant woman or child, make sure it is validated for these conditions. (heart.org)
  • A blood pressure reading of 120/80 is considered ideal. (cedars-sinai.edu)
  • Some women may have had it long before becoming pregnant, but didn't know it until they got their blood pressure checked at their prenatal visit . (medlineplus.gov)
  • Preeclampsia is a sudden increase in blood pressure after the 20th week of pregnancy. (medlineplus.gov)
  • Your health care provider will check your blood pressure and urine at each prenatal visit. (medlineplus.gov)
  • Even though it's closely related to dietary and lifestyle habits, many people try to rely on medication alone to solve their blood pressure problems. (draxe.com)
  • In fact, I'm going to tell you about 13 foods, including everything from snacks to juice to herbs, that have been scientifically proven to lower blood pressure. (draxe.com)
  • Instead of rushing toward conventional medicine, give these foods that lower blood pressure a try. (draxe.com)
  • One of the most desirable benefits of pomegranate juice includes the ability it has to lower blood pressure naturally. (draxe.com)
  • The science is in: Pomegranate juice has major blood pressure-lowering ability, both in short- and long-term studies. (draxe.com)
  • Albumin is the main protein in plasma, and it functions to regulate the colloidal osmotic pressure of blood. (wikipedia.org)
  • oxygen
  • These contain hemoglobin, an iron-containing protein, which facilitates oxygen transport by reversibly binding to this respiratory gas and greatly increasing its solubility in blood. (wikipedia.org)
  • In most insects, this "blood" does not contain oxygen-carrying molecules such as hemoglobin because their bodies are small enough for their tracheal system to suffice for supplying oxygen. (wikipedia.org)
  • protein
  • For analysis of biomarkers in blood serum samples, it is possible to do a pre-separation by free-flow electrophoresis that usually consists of a depletion of serum albumin protein. (wikipedia.org)
  • typically
  • Hospitals typically keep some blood units on their shelves, but may call for more at any time, such as in case of large scale emergencies. (redcrossblood.org)
  • bone
  • Blood meal, bone meal, and other animal by-products are permitted in certified organic production as soil amendments, though they cannot be fed to organic livestock. (wikipedia.org)
  • Blood meal is different from bone meal in that blood meal contains a higher amount of nitrogen, while bone meal contains phosphorus. (wikipedia.org)
  • known
  • Blood Song (also known Dream Slayer) is a 1982 American horror film directed by Robert Angus and Alan J. Levi, produced by Frank Avianca and Lenny Montana, and starring Frankie Avalon and Donna Wilkes. (wikipedia.org)
  • Diabetes
  • OBJECTIVE -The objective of this study was to determine whether cinnamon improves blood glucose, triglyceride, total cholesterol, HDL cholesterol, and LDL cholesterol levels in people with type 2 diabetes. (diabetesjournals.org)
  • clinical
  • The NBA has produced tools to assist with the transfer of product between providers including Managing Blood and Blood Product Transfers and the BloodNet Blood Fridges Module to improve health provider confidence with product cold chain integrity and a Better Practice Case Study on converting unused thawed clinical fresh frozen plasma to extended life plasma, thus reducing its wastage rates. (blood.gov.au)
  • A targeted range of wastage reduction promotional material have been developed by the NBA including swing-tags for blood bags, posters, magnets, pens and intra-hospital transfer cooler bags aimed at clinical staff. (blood.gov.au)
  • The Blood and Marrow Transplant Clinical Trials Network (BMT CTN) was established in October 2001 to conduct large multi-institutional clinical trials. (emmes.com)