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Calcium SignalingCalcium ChannelsCalcium, DietaryCalcium Channel BlockersCalcium CarbonateCalcium PhosphatesCalcium IsotopesCalcium ChlorideCalcium Channels, L-TypeAngiotensin II Type 1 Receptor BlockersPotassium Channel BlockersCalcium OxalateCalcium GluconateNifedipineCalcium RadioisotopesCalcium Channels, N-TypeSodium Channel BlockersEgtazic AcidMembrane PotentialsVerapamilCalcium Channel AgonistsDihydropyridinesCalcium CompoundsDiltiazemPatch-Clamp TechniquesCells, CulturedDose-Response Relationship, DrugCalcimycinRats, Sprague-DawleyPotassiumChelating AgentsKineticsTime FactorsElectrophysiologyFura-2Calcium HydroxideMagnesiumThapsigarginAdrenergic beta-AntagonistsPhosphorusNeuronsCalcium SulfateParathyroid HormoneNitrendipineomega-Conotoxin GVIARats, WistarNicardipineRyanodine Receptor Calcium Release ChannelPotassium ChannelsNimodipineLanthanumMibefradilCalcium CitrateIon ChannelsRabbitsCytosolSodiumIon Channel GatingAmlodipineomega-ConotoxinsS100 Calcium Binding Protein GAdenosine TriphosphateCalcium Channels, P-TypeTetrazolesCalcium PyrophosphateCalcium Metabolism DisordersCalcium-Binding ProteinsMyocardiumAntihypertensive AgentsIonophoresBenzimidazolesElectric StimulationFluorescent DyesCalcium Channels, Q-TypeIntracellular FluidInositol 1,4,5-Trisphosphate ReceptorsCaffeineSpider VenomsIon TransportAngiotensin-Converting Enzyme InhibitorsCalcium Channels, R-TypeSignal TransductionIsradipineCalciumCalmodulinIonomycinAngiotensin Receptor AntagonistsMuscle ContractionAequorinEnzyme InhibitorsFlunarizineInositol 1,4,5-TrisphosphateStrontiumCell LineTetrodotoxinRyanodineHydrogen-Ion ConcentrationHypertensionomega-Agatoxin IVAKidney Calculi
CCBsDiltiazemVerapamilChannelHypertensionAntagonistsMedicationsDrugsAngiotensin-converInhibitorsIntracellular calciumBeta-blockerIonsToxicityPotassiumOlmesartan MedoxomilDecreaseAngina pectorisSymptomsChannelsDiureticsVerapamilDihydropyridineBeta blockerAntagonistChannel blockers preventErectile DysfunctionAngiotensin-convertinBlood vesselsAmlodipineSystemicNitratesTransmembrane influx of calciumNimodipineInfluxHypertension and anginaAnginaVoltage gated cFelodipineCilnidipineInhibitionOverdoseTreatment of hypertensionArterialHigh blood prMedicinesSearchPatientsMethodsHeart
CCBs19
Diltiazem8
  • The image below illustrates the chemical structure of the calcium channel blocker diltiazem. (medscape.com)
  • Amlodipine, Isradipine, Diltiazem, Felodipine, Nicardipine are the kind of calcium channel blocker drugs utilized for the treatment of heart issues, angina, sporadic pulses (arrhythmia) and blood vessel conditions, like Raynaud's disease. (medgadget.com)
  • You decide to treat her by ventricular rate limitation with a calcium channel blocker and wonder whether you should use diltiazem or verapamil. (bestbets.org)
  • Experiments were performed to determine the effect of the calcium-channel blockers verapamil and diltiazem on ethanol preference in monkeys. (duke.edu)
  • Diltiazem (Cardizem) is a calcium channel blocker (CCB). (nsurcoin.com)
  • The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model Dominant mutations in sarcomere protein genes cause hypertrophic cardiomyopathy, an inherited human disorder with increased ventricular wall thickness, myocyte hypertrophy, and disarray. (vanast.info)
  • Calcium-channel blockers are useful for the treatment of hypertrophic cardiomyopathy (HCM), but, their adverse effects, especially, those of diltiazem, have not been of much concern. (vanast.info)
  • Verapamil- or diltiazem-type calcium channel blockers may affect ECG and/or blood pressure. (nih.gov)
Verapamil4
Channel82
Hypertension3
  • The third observation was that the blockade of these calcium channels and the rejuvenation could be accomplished with the dihydropyridine isradipine - a drug that has been used for decades to treat hypertension. (hearingreview.com)
  • Calcium antagonists are one of the most popular group of drugs for treating high blood pressure (hypertension) and they are the most likely to cause severe stomach bleeding in the elderly. (healthy.net)
  • He slapped his head and said So, we have been making great strides forward, but medicine podcasts hypertension they have been relegated one after another, and after returning from training, they are relegated, so they stand calcium and high cholesterol drug for hypertension still. (jewishledger.com)
Antagonists2
  • Available research indicates that first-generation calcium antagonists may have a negative effect in individuals with CHF, indicating that these medications should be administered with extreme caution in patients with a substantial decrease in left ventricular systolic function. (sympdisease.com)
  • No correlation with risk was seen for use of diuretics, β-blockers, or angiotensin II antagonists. (cancertherapyadvisor.com)
Medications1
Drugs3
  • Carvedilol belongs to a class of drugs called beta-blockers. (medicalnewstoday.com)
  • Common examples of sulfonamides, or "sulfa drugs," include sulfasalazine (Azulfidine, Azulfidine EN-tabs) , acetazolamide xr (Diamox Sequels), acetyl sulfisoxazole pediatric suspension (Gantrisin), sulfisoxazole (Trixazole), and Zonegran (zonisamide (Zonegran) . (everydayhealth.com)
  • Some drugs (eg, beta-blockers) have potential adverse effects when discontinued abruptly and should be given parenterally in the perioperative period. (medscape.com)
Angiotensin-conver1
  • thus, the popularity of such drug combinations as an angiotensin-converting enzyme (ACE) inhibitor/diuretic, an angiotensin-receptor blocker/diuretic, or a b blocker/diuretic. (medscape.com)
Inhibitors1
  • Pretreatment with mediator blockers, arachidonic- acid metabolite inhibitors, and an intracellular calcium antagonist were examined and compared to findings with similar experiments using cotton bract extracts. (cdc.gov)
Intracellular calcium4
  • The maintenance of intracellular calcium homeostasis is among the most important homeostatic functions of the nervous system as it allows the calcium ion to function as a chemical messenger. (auburn.edu)
  • Often damage to the central nervous system (CNS) disrupts intracellular calcium homeostasis, causing increased intracellular concentrations of calcium ions, which result in cellular dysfunction and/or death and manifests as changes in the organism's behavior. (auburn.edu)
  • Following that, one dihydropyridine CCB (nimodipine) was administered chronically to mice with and without chronic co-exposure to 15 ppm Methylmercury (MeHg), a toxicant known to elevate intracellular calcium concentration and cause cognitive and motor impairments. (auburn.edu)
  • These agents interfere with calcium uptake by smooth muscle cells that are dependent on intracellular calcium for contraction. (medscape.com)
Beta-blocker4
  • Carvedilol is a beta-blocker . (medicalnewstoday.com)
  • 133 of these patients have continued taking the medication for an average of 25 +/- 13 months because their quality of life improved compared with what they experienced with their former therapy (usually beta blocker). (vanast.info)
  • This can help differential from Beta Blocker (BB) toxicity, where the patients often have altered mental status. (rebelem.com)
  • Because decreasing the heart's workload also helps limit tissue damage, a beta-blocker is usually given to slow the heart rate. (msdmanuals.com)
Ions4
  • Calcium ions are essential for normal cellular function but in excess can kill,' Dr. Surmeier explained. (hearingreview.com)
  • When this reaches the threshold membrane potential , it's the cue for voltage-gated calcium channels to open, allowing a large influx of calcium ions, which depolarizes it further. (osmosis.org)
  • Inhibits transmembrane influx of calcium ions into smooth muscle, which, in turn, inhibits contraction of the muscle fibers. (medscape.com)
  • Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. (bvsalud.org)
Toxicity1
  • Additionally, the beneficial effects of nimodipine + MeHg exposure support the hypothesis that MeHg-induced changes in calcium homeostasis mediate the behavioral toxicity seen with MeHg exposure. (auburn.edu)
Potassium1
Olmesartan Medoxomil2
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  • In hydrochlorothiazide olmesartan medoxomil beta blockers and caffeine reddit this case, only Hua Tianyu, who had recovered his lazy look, and Duke Yueqi behind Emperor Sailu were still standing. (gujaratmitra.in)
Decrease1
  • Both digitalis glycosides and β-blockers slow atrioventricular conduction and decrease heart rate. (nih.gov)
Angina pectoris1
  • Blockers and beta blockers for chronic stable angina pectoris in patients with hypertrophic. (vanast.info)
Symptoms2
  • It improves the filling of the heart and like beta-blockers, reduces symptoms such as chest pain, breathlessness and palpitations. (vanast.info)
  • Diabetes: Monitor glucose as β-blockers may mask symptoms of hypoglycemia or worsen hyperglycemia. (nih.gov)
Channels5
Diuretics6
  • Several of the calcium channel blockers are now available in generic forms and some are available as combinations with diuretics and lipid lowering agents. (nih.gov)
  • Several antihypertensive medications, including thiazide diuretics, beta-blockers, angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and calcium channel blockers, in principle, can be used as initial monotherapy in patients with hypertension. (medscape.com)
  • If the BP goal is not achieved, thiazide-type diuretics should be used as initial therapy for most patients, either alone or in combination with one of the other classes (ie, ACE inhibitors, ARBs, beta-blockers, calcium channel blockers) that have also been shown to reduce one or more hypertensive complications in randomized controlled outcome trials. (medscape.com)
  • at the end, diuretics were found to be as effective at preventing major coronary events, or even superior in preventing heart failure, compared with calcium channel blockers or ACE inhibitors. (medscape.com)
  • The investigative team, led by Anthony P. Khawaja, MBBS, PhD, UCL Institute of Ophthalmology, additionally indicated that non-selective and selective beta blockers were associated with lower intraocular pressure (IOP), while a suggestive association was found between the use of high-ceiling diuretics and lower IOP. (consultantlive.com)
  • In agreement was Richard Devereux, MD, professor of medicine, Weill Medical College of Cornell University, New York, NY, who noted the high use of diuretics in the beta-blocker arm (67%) and perindopril in the amlodipine arm (63%) as evidence that the effects cannot 'solely be attributed to the initial drug in either arm. (formularywatch.com)
Verapamil5
Dihydropyridine4
  • Dihydropyridine calcium channel blockers are derivatives of 1,4-dihydropyridine that are used as L-type calcium channel blockers. (wikipedia.org)
  • Dihydropyridine class L-type calcium channel blockers include, in alphabetical order (brand names vary in different countries): The pharmaceutical drug finerenone is also a dihydrophyridine derivative, but does not act as a calcium channel blocker but as an antimineralocorticoid. (wikipedia.org)
  • We found similar results in a stratified analysis of patients who received only dihydropyridine calcium-channel blockers. (cmaj.ca)
  • SULAR ® (nisoldipine) is an extended release tablet dosage form of the dihydropyridine calcium channel blocker nisoldipine. (rxlist.com)
Beta blocker4
  • Carvedilol is a beta-blocker . (medicalnewstoday.com)
  • An antihypertensive therapeutic strategy that starts with the calcium antagonist amlodipine is superior to one starting with the beta-blocker atenolol in preventing coronary heart disease (CHD) events, Peter S. Sever, MD, reported at the ACC Annual Scientific Session 2005. (formularywatch.com)
  • As expected, the beta-blocker/diuretic regimen was associated with a 32% excess in the development of new diabetes. (formularywatch.com)
  • Because decreasing the heart's workload also helps limit tissue damage, a beta-blocker is usually given to slow the heart rate. (msdmanuals.com)
Antagonist1
  • However, the main ingredient is called a calcium-channel antagonist. (medlineplus.gov)
Channel blockers prevent2
Erectile Dysfunction16
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Angiotensin-convertin1
  • Amlodipine, a calcium-channel blocker, is used alone or with benazepril, an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. (pharmacycode.com)
Blood vessels1
  • Calcium channel blockers, also called calcium antagonists, relax and widen blood vessels by affecting the muscle cells in the arterial walls. (medicalpublications.org)
Amlodipine1
  • Amlodipine mainly exists as its salt with Besilate and it works by blocking the transmembrane influx of calcium into the vascular and cardiac smooth muscles. (pharmaffiliates.com)
Systemic2
  • Our findings confirm the known IOP-lowering effect of systemic beta-blockers, quantifying the effect on a population level, and identify other potential systemic medication modifiers of glaucoma risk," investigators wrote. (consultantlive.com)
  • Systemic, Intrathecal, and Intracerebroventricular Antihyperalgesic Effects of the Calcium Channel Blocker CTK 01512-2 Toxin in Persistent Pain Models. (bvsalud.org)
Nitrates1
  • Calcium channel blockers and nitrates both decrease LES pressure but do not improve LES relaxation. (medscape.com)
Transmembrane influx of calcium1
  • Inhibits transmembrane influx of calcium ions into smooth muscle, which, in turn, inhibits contraction of the muscle fibers. (medscape.com)
Nimodipine2
  • Previous studies have demonstrated efficacy of nimodipine, an L-type calcium channel blocker, on reversing these changes in salicylate and quinine induced tinnitus in rat models (Jastreboff, 1991). (cdc.gov)
  • However, human trials with nimodipine have not consistently demonstrated efficacy as treatment for tinnitus, prompting examination of other calcium channel blockers. (cdc.gov)
Influx2
Hypertension and angina1
Angina3
Voltage gated c2
  • While all affect the L type voltage gated calcium channel, the structure and site of interaction within the channel varies among the agents. (nih.gov)
  • It acts as an N-type voltage-gated calcium channel (VGCC) blocker and shows a prolonged effect on preventing and reducing nociception . (bvsalud.org)
Felodipine1
Cilnidipine1
  • Cilnidipine, an L-/N-type calcium channel blocker (CCB), has unique organ-protective properties due to suppression of hyperactivity in the sympathetic nervous system and renin-angiotensin system (RAS). (tokushima-u.ac.jp)
Inhibition1
Overdose2
  • Calcium-channel blocker overdose occurs when someone takes more than the normal or recommended amount of this medicine. (medlineplus.gov)
  • Clinical question: What is the best management approach for adults who are admitted to the hospital with a calcium channel blocker (CCB) overdose? (the-hospitalist.org)
Treatment of hypertension1
Arterial1
  • Thus, the major effects of the calcium channel blockers are relaxation of vascular and arterial smooth muscle cells resulting in arterial vasodilation. (nih.gov)
High blood pr2
Medicines2
  • Other medicines may also contain calcium-channel blockers. (medlineplus.gov)
  • Available at: https://www.ema.europa.eu/en/medicines/human/referrals/trimetazidine. (drugs.com)
Search1
  • These images are a random sampling from a Bing search on the term "Calcium Channel Blocker. (fpnotebook.com)
Patients3
  • Results Of the 7100 patients admitted to hospital because of hypotension while receiving a calcium-channel blocker, 176 had been prescribed a macrolide antibiotic during either the risk or control intervals. (cmaj.ca)
  • Interpretation In older patients receiving a calcium-channel blocker, use of erythromycin or clarithromycin was associated with an increased risk of hypotension or shock requiring admission to hospital. (cmaj.ca)
  • Preferential use of azithromycin should be considered when a macrolide antibiotic is required for patients already receiving a calcium-channel blocker. (cmaj.ca)
Methods1
  • Methods We conducted a population-based, nested, case-crossover study involving people aged 66 years and older who had been prescribed a calcium-channel blocker between Apr. (cmaj.ca)
Heart3