• What causes heavy vaginal bleeding w/ severe abdo pain? (healthtap.com)
  • Women 45 and over had a high risk of severe vaginal bleeding after receiving mRNA Covid shots, Swedish researchers found after studying almost 3 million women. (substack.com)
  • Vaginal bleeding is not merely painful and uncomfortable. (substack.com)
  • Because of its size and reliance on formal medical diagnoses rather than self-reporting of vaginal bleeding, the study offers the strongest evidence yet that the connection between Covid shots and bleeding is real. (substack.com)
  • Whole lotta bleeding going on: fifth column is the "crude" rate ratio, showing a 40-45 percent increased risk of severe vaginal bleeding. (substack.com)
  • One of the primary symptoms of cervical cancer is irregular vaginal bleeding. (healthline.com)
  • Baby girls can have some minor vaginal bleeding. (seattlechildrens.org)
  • Vaginal bleeding (other than newborn) is not normal. (seattlechildrens.org)
  • Vaginal bleeding is abnormal if it occurs between regular periods. (seattlechildrens.org)
  • Vaginal bleeding can be a sign of pregnancy. (seattlechildrens.org)
  • Vaginal bleeding of unknown cause before puberty. (seattlechildrens.org)
  • When you notice some spotting or bleeding after vaginal sex - perhaps on your bed sheets, in your underwear or on the toilet paper - it's natural to be concerned. (yahoo.com)
  • If you're dealing with bleeding after sex, vaginal dryness could be to blame. (yahoo.com)
  • Friction from intercourse "can lead to minuscule tears in the vaginal tissues, leading to bleeding after sex," Barbieri said. (yahoo.com)
  • Vaginal dryness that's causing painful sex or bleeding is quite common among p atients in perimenopause and menopause, Barbieri noted, but can be "easily remedied" by using lubricants or topical vaginal estrogen cream. (yahoo.com)
  • Vaginal dryness, which is common among menopausal women, creates extra friction during sex that can lead to some bleeding. (yahoo.com)
  • Sexual assault can also cause vaginal bleeding. (yahoo.com)
  • Annovera is a reusable donut-shaped (ring), non-biodegradable, flexible vaginal system that is placed in the vagina for three weeks followed by one week out of the vagina, at which time women may experience a period (a withdrawal bleed). (fda.gov)
  • Adequate diagnostic measures, including endometrial sampling when indicated, should be undertaken to rule out malignancy in all cases of undiagnosed persistent or recurring abnormal vaginal bleeding. (theodora.com)
  • A pregnant woman with vaginal bleeding must be evaluated promptly. (msdmanuals.com)
  • Ectopic pregnancy or causes of severe vaginal bleeding (eg, inevitable or incomplete abortion, ruptured hemorrhagic corpus luteum cyst) can lead to hemorrhagic shock. (msdmanuals.com)
  • Some conditions causing pelvic pain also cause vaginal bleeding. (msdmanuals.com)
  • The patient should be asked questions to determine whether it is certain that the source of the bleeding is vaginal. (msdmanuals.com)
  • Urinary or gastrointestinal tract bleeding can sometimes be mistaken for vaginal bleeding. (msdmanuals.com)
  • Physical examination directed at evaluating vaginal bleeding includes review of vital signs for fever and signs of hypovolemia (tachycardia, hypotension). (msdmanuals.com)
  • Stop-the-Bleed" is a national White House-initiated awareness campaign and call-to-action. (google.com)
  • Nearly half-dozen people participated in the Stop the Bleed course Tuesday. (yahoo.com)
  • Pack the wound with a gauze or whatever clean cloth or material you have, put pressure on the wound to help stop the bleed, and if needed and the bleeding doesn't stop, you tie a tourniquet around that body part and you wait until EMS arrives," Hollins said. (yahoo.com)
  • Stop the bleed and save a life," Hollins said. (yahoo.com)
  • The Stop the Bleed course is available to anyone or any group, and they will come to you. (yahoo.com)
  • Every year on Stop the Bleed Day, we take the time to educate communities about life-threatening bleeding and how they can help others in need before medical help arrives. (redcrosschat.org)
  • Acute gastrointestinal (GI) bleeding is a potentially life-threatening abdominal emergency that remains a common cause of hospitalization. (medscape.com)
  • See Pediatric Gastrointestinal Bleeding for more information on this topic. (medscape.com)
  • Anus Melena - upper gastrointestinal bleeding Hematochezia - lower gastrointestinal bleeding, or brisk upper gastrointestinal bleeding Vascular Ruptured aneurysm Aortic transection Iatrogenic injury Bleeding arises due to either traumatic injury, underlying medical condition, or a combination. (wikipedia.org)
  • It irritates your stomach lining and can trigger gastrointestinal upset, ulcers and bleeding. (hopkinsmedicine.org)
  • Abnormal uterine bleeding (AUB) is bleeding from the uterus that is longer than usual or that occurs at an irregular time. (medlineplus.gov)
  • Teens may have abnormal bleeding during the year after their periods start. (seattlechildrens.org)
  • Some birth control medicines can cause breakthrough or abnormal bleeding. (seattlechildrens.org)
  • Although rare, bleeding with intercourse can be a sign of cervical cancer "due to the increased vascularity of abnormal cells," Ross said. (yahoo.com)
  • 5 days or abnormal bleeding occurs at the expected date of menstrual periods or pregnancy is suspected for any other reason, a pregnancy test should be taken to exclude pregnancy. (who.int)
  • What are the symptoms of Severe Bleeding? (acko.com)
  • Symptoms of Severe Bleeding are as follows. (acko.com)
  • It is also important to seek medical help if the bleeding is accompanied by other symptoms such as dizziness , rapid heartbeat, or fainting . (acko.com)
  • The symptoms, which include severe bleeding and bruising, develop suddenly in individuals after smoking the drug and get worse over time. (briefupdates.com)
  • Call 911 or local emergency services, or go to the nearest emergency room immediately, if you're showing symptoms of bleeding esophageal varices. (healthline.com)
  • What are the symptoms of bleeding esophageal varices? (healthline.com)
  • Esophageal varices often don't cause any symptoms until they rupture and bleed. (healthline.com)
  • Once they rupture, symptoms vary depending on the severity of the bleeding. (healthline.com)
  • Dengue usually results in mild or no symptoms but it can also lead to high fever, severe headache and vomiting. (mirror.co.uk)
  • People with these severe symptoms should seek medical care right away. (mirror.co.uk)
  • Occasionally, there are severe instances of infection in which people can develop bleeding manifestations, neurologic symptoms, or even possibly death. (cdc.gov)
  • Treatment with investigational efanesoctocog alfa (formerly BIVV001) -- a new class of factor VIII replacement therapy -- prevented bleeding episodes in patients with severe hemophilia A, according to results from the phase III XTEND-1 trial . (medpagetoday.com)
  • Collectively, these results show that by maintaining high sustained factor VIII activity, once-weekly efanesoctocog alfa provided substantial improvements in clinical outcomes and quality of life for patients with severe hemophilia A," the authors wrote. (medpagetoday.com)
  • While normalizing factor VIII levels helps protect patients with hemophilia A from spontaneous and traumatic bleeding, thus preserving joint health, von Drygalski and colleagues pointed out that the interaction between factor VIII and endogenous von Willebrand factor limits the half-life of current factor VIII replacement products to 8 to 19 hours. (medpagetoday.com)
  • 1%) or a documented genotype known to produce severe hemophilia A were included. (medpagetoday.com)
  • Prophylaxis for hemophilia is the scheduled infusion of the missing clotting factor with pre-specified dose, with the intention of preventing bleeds and subsequent hemophilic arthropathy. (haematologica.org)
  • It is the treatment of choice for patients with severe hemophilia A in countries with available resources. (haematologica.org)
  • The European Pediatric Network for Hemophilia Management (PedNet) first specified primary prophylaxis as starting before two years of age OR before the second joint bleed, 5 and The World Federation of Hemophilia (WFH) as starting before the age of three years AND before the second joint bleed, in the documented absence of osteochondral joint disease. (haematologica.org)
  • SAN RAFAEL, Calif. - BioMarin Pharmaceutical Inc. (NASDAQ: BMRN) today announced positive results from its ongoing global Phase 3 GENEr8-1 study of valoctocogene roxaparvovec, an investigational gene therapy for the treatment of adults with severe hemophilia A. This is the largest global Phase 3 study to date for any gene therapy in hemophilia, with 134 participants. (checkorphan.org)
  • Kids with hemophilia can bleed easily or longer than normal. (kidshealth.org)
  • You will learn how and when to control bleeding by applying a tourniquet and hemostatic dressing. (redcross.org)
  • The Department of Homeland Security provides information, so you know what to do in a bleeding emergency, including how to apply a tourniquet. (cdc.gov)
  • Clients considered or suspected to have minor bleeding disorders can be circumcised safely in settings where blood products are available. (cdc.gov)
  • Bleeding adverse events in men with potential bleeding disorders are serious and can be fatal. (cdc.gov)
  • Injuries and some medical disorders can cause bleeding. (standardfirstaidtraining.ca)
  • Severe dengue can result in bleeding from the gums, abdominal pain and eventually death. (mirror.co.uk)
  • In an editorial accompanying the study , Cindy Leissinger, MD, of Tulane University School of Medicine in New Orleans, said a major advantage of efanesoctocog alfa "is its value as a true factor VIII replacement that can be used to treat acute bleeding and can be measured by standard laboratory assays to allow for monitoring and dose adjustments when needed. (medpagetoday.com)
  • We hypothesized that clinical risk factors could be identified within 2 weeks of onset of severe (stage 3 or 4) acute gut GVHD for identifying a patient population with a very poor outcome. (nature.com)
  • Doctors refer to these as bleeding ulcers. (medicalnewstoday.com)
  • Infections and some medications can cause bleeding ulcers. (medicalnewstoday.com)
  • Using the correct treatment, doctors can cure bleeding ulcers. (medicalnewstoday.com)
  • Diagnosis and treatment of bleeding ulcers typically involve an endoscopy . (medicalnewstoday.com)
  • Taking certain pain relief medications known as nonsteroidal anti-inflammatory drugs (NSAIDs) at high doses or for extended periods can cause peptic or bleeding ulcers. (medicalnewstoday.com)
  • NSAIDs can also decrease the blood's clotting ability, which can make ulcers more likely to bleed. (medicalnewstoday.com)
  • Overall, a third mRNA dose raised the risk of severe, medically diagnosed bleeding episodes by 25-45 percent. (substack.com)
  • The most common side effects in women using Annovera are similar to those of other combined hormonal contraceptive products and include headache/migraine, nausea/vomiting, yeast infections, abdominal pain, dysmenorrhea (painful menstruation), breast tenderness, irregular bleeding, diarrhea and genital itching. (fda.gov)
  • If the bleeding is mild, you might only notice black, tarry stools (melena) that results from swallowing the blood. (healthline.com)
  • It's not uncommon to experience cramping or mild bleeding after a Pap smear. (healthline.com)
  • When you're pregnant, having sex can lead to spotting or mild bleeding, " caused by increased blood flow and inflammation of the vagina and cervix," Ross said. (yahoo.com)
  • 20 IU dL -1 ) are asymptomatic or exhibit only mild bleeding, whereas others experience severe bleeding, usually following trauma. (tau.ac.il)
  • Data reported from eight country VMMC programs during 2015-2016 revealed that bleeding resulting in hospitalization for ≥3 days was the most commonly reported qualifying adverse event. (cdc.gov)
  • These deaths served, in part, as the impetus for broadening the adverse event notification process to include some nonfatal adverse events, including bleeding resulting in hospitalization for ≥3 days, in January 2015. (cdc.gov)
  • A total of 152 bleeding events were observed during the index hospitalization. (123dok.net)
  • Bleeding severity according to VARC was associated with a gradual increase in mortality, which was comparable to the BARC, TIMI, GUSTO, and the modified VARC classifications. (123dok.net)
  • Conclusions--The VARC bleeding definition offers a severity stratification that is associated with a gradual increase in mortality and prognostic information comparable to established bleeding definitions. (123dok.net)
  • This bleeding occurs when a vein is injured or torn. (acko.com)
  • This course is for individuals who have a greater than average chance of witnessing or being involved in an injury event in which heavy bleeding occurs and professional medical care is not readily available or is overwhelmed, such as law enforcement, private security, workplace emergency response team personnel and staff at large events, campuses or large occupied structures. (google.com)
  • Pregnancy should be ruled out, if no bleed occurs in the next pill-free period following the use of levonorgestrel after regular hormonal contraception. (who.int)
  • Irregular bleeding is a common sign of cervical cancer. (healthline.com)
  • Irregular bleeding happens more than 2 cycles (2 months) and using birth control medicines. (seattlechildrens.org)
  • When bleeding events did occur, a single injection of efanesoctocog alfa 50 IU/kg provided effective resolution for 97% of events. (medpagetoday.com)
  • Bleeding may be heavier or lighter than usual and occur often or randomly. (medlineplus.gov)
  • The bleeding may be very heavy or light, and can occur often or randomly. (medlineplus.gov)
  • Bleeding can occur internally, or externally either through a natural opening such as the mouth, nose, ear, urethra, vagina or anus, or through a puncture in the skin. (wikipedia.org)
  • Bleeding esophageal varices occur when swollen veins (varices) in your lower esophagus rupture and bleed. (healthline.com)
  • But heavy bleeding or severe cramping shouldn't occur. (healthline.com)
  • Preventing and controlling bleeding episodes that occur spontaneously or due to injury is the cornerstone of haemophilia care. (who.int)
  • Bleeding may also occur if you've had rougher-than-usual sex or used certain sex toys, which can tear or injure the area, Barbieri said. (yahoo.com)
  • We can state that preliminary findings indicate Tyre suffered extensive bleeding caused by a severe beating, and that his observed injuries are consistent with what the family and attorneys witnessed on the video of his fatal encounter with police on January 7, 2023. (wreg.com)
  • This can lead to severe bleeding and life threatening complications, including death. (healthline.com)
  • 1-4 Owing to the substantial differences in invasiveness between TAVI and SAVR, major bleeding complications and packed red blood cell (PRBC) transfusions have been shown to be 2 to 3 times less frequent among patients undergoing TAVI, com- pared to those undergoing SAVR, in the PARTNER trial. (123dok.net)
  • This can increase bleeding from a scratch or irritated spot on your cervix. (healthline.com)
  • These infections may make your cervix more tender, and blood vessels may bleed more following the procedure. (healthline.com)
  • If you have a friable cervix , you may experience heavier spotting and bleeding following a Pap smear. (healthline.com)
  • This bleeding is likely coming from your cervix. (healthline.com)
  • The delicate tissues of your cervix can bleed after a brush or swab scratches the surface. (healthline.com)
  • It's possible for deep penetration that bruises the cervix to lead to some discomfort and bleeding. (yahoo.com)
  • Hormonal changes during pregnancy can make the cervix more tender and more susceptible to bleeding from sex. (yahoo.com)
  • While it is the least severe type of bleeding, it can still result in significant blood loss if left untreated. (acko.com)
  • A severe bleeding ulcer left untreated can cause rapid blood loss and even death. (medicalnewstoday.com)
  • Cerebral hemorrhage - a type of intracranial hemorrhage, bleeding within the brain tissue itself. (wikipedia.org)
  • It can also be used to take tissue samples and treat bleeding. (healthline.com)
  • During a Pap smear, a cervical polyp may bleed, which increases the amount of surface tissue that's bleeding. (healthline.com)
  • Inflamed and irritated tissue can bleed with friction and touch," she explained. (yahoo.com)
  • If these are stimulated during sex, the tissue can bleed. (yahoo.com)
  • The pathophysiology of massive blood loss is complex, comprising a wide range of physiologic derangements arising from tissue injury, bleeding, and transfusion of blood or blood products. (medscape.com)
  • If bleeding is persistent and prolonged, it may lead to tissue hypoxemia, severe acidosis, multiorgan dysfunction, or death. (medscape.com)
  • Kaplan-Meier survival analysis was used to assess the occurrence of the first joint bleed and cumulative incidences of start of prophylaxis and CVAD use, while accounting for differences in follow up due to inhibitor development. (haematologica.org)
  • Still, you have to know how to treat various bleeding incidences', like cuts and bleeding noses , as well as when to get medical assistance. (standardfirstaidtraining.ca)
  • There are different types of wounds which may cause traumatic bleeding. (wikipedia.org)
  • The First Aid for Severe Bleeding Online course will prepare you to recognize severe, life-threatening bleeding emergencies and to take action to stop the flow of blood. (redcross.org)
  • Some severe injuries can lose a little blood. (standardfirstaidtraining.ca)
  • Also, cuts on the mouth, face, and head might bleed a lot as there are lots of blood vessels around those areas. (standardfirstaidtraining.ca)
  • Severe Bleeding refers to a condition characterised by the loss of a significant amount of blood from the body. (acko.com)
  • Applying cold compresses to constrict blood vessels and slow down bleeding. (acko.com)
  • This type of bleeding is typically characterised by bright red, pulsating blood that comes out in spurts or jets. (acko.com)
  • Venous bleeding usually produces a steady flow of dark red blood. (acko.com)
  • It is less severe than arterial bleeding, but still it should be treated promptly to prevent excessive blood loss. (acko.com)
  • Bleeding, hemorrhage, haemorrhage or blood loss, is blood escaping from the circulatory system from damaged blood vessels. (wikipedia.org)
  • Intracerebral hemorrhage - bleeding in the brain caused by the rupture of a blood vessel within the head. (wikipedia.org)
  • If an ulcer develops at the site of a blood vessel, it can cause bleeding. (medicalnewstoday.com)
  • Excessive ulcer bleeding is a medical emergency as it can cause rapid blood loss and death. (medicalnewstoday.com)
  • They presented with significant clinical effects like blood in their urine, spontaneous bleeding from their nose, easy bruising and pretty sick people out there," Fred Aleguas, the co-managing director of the Florida Poison Information Center in Tampa, told Fox 13 . (briefupdates.com)
  • Left uncontrolled, severe bleeding can cause extremely low blood pressure and lead to shock . (healthline.com)
  • The higher the portal blood pressure, the greater the risk of bleeding. (healthline.com)
  • Bleeding not contained by pads with large amount of red blood from vagina. (seattlechildrens.org)
  • In that case, the blood may be part of menstruation, not actual postcoital bleeding. (yahoo.com)
  • Transfusion of blood and blood products is usually necessary during a bleeding catastrophe. (medscape.com)
  • And, because it thins your blood, it can be dangerous for people who are at higher risk of bleeding. (hopkinsmedicine.org)
  • After the third mRNA dose, post-menopausal women had over a 40 percent higher risk of severe bleeding. (substack.com)
  • Overall, 80% of group A and 85% of group B patients had no spontaneous bleeding episodes during the prophylaxis periods. (medpagetoday.com)
  • Younger women also had a higher risk of bleeding episodes, although the researchers said hidden factors unrelated to the vaccine might have driven that finding. (substack.com)
  • In about 9 percent of cases , severe bleeding episodes are a sign of cancer of the endometrium, the lining of the uterus. (substack.com)
  • For all three doses combined, episodes of severe bleeding in older women rose by about 20 percent before correction and 15 percent after. (substack.com)
  • Neither he nor his family had a history of nosebleeds or bleeding diathesis. (cdc.gov)
  • Someone falls and they injury their head and they have bleeding from their head, a gunshot wound, ATV accident…any type of trauma, any type of severe bleeding. (yahoo.com)
  • If you are experiencing severe eye pain, significant visual impairment, or bleeding, or if you think there is a chance of a foreign body or trauma to the eye, you should be seen in person. (intermountainhealthcare.org)
  • However, bleeding following a Pap smear can be a sign of many other issues, including an infection, an STI , or pregnancy. (healthline.com)
  • Ectopic pregnancy may continue, despite the occurrence of uterine bleeding. (who.int)
  • Incidence and outcome of bleeding before the 20th week of pregnancy: prospective study from general practice. (msdmanuals.com)
  • The following factors can increase the risk of Severe Bleeding. (acko.com)
  • In the current study, we analyzed the risk factors for severe bleeding after PCNL. (archivesofmedicalscience.com)
  • The stopping or controlling of bleeding is called hemostasis and is an important part of both first aid and surgery. (wikipedia.org)
  • Sudden green vomiting w/ diarrhea and then bleeding a week before my period. (healthtap.com)
  • Among 133 patients, almost all males, who received once-weekly prophylaxis with efanesoctocog alfa 50 IU/kg for 52 weeks (group A), the median annualized bleeding rate was 0 (interquartile range 0-1.04), and the estimated mean annualized bleeding rate was 0.71 (95% CI 0.52-0.97), reported Annette von Drygalski, MD, PharmD, of the University of California San Diego, and colleagues. (medpagetoday.com)
  • In a smaller group of 26 men who received on-demand treatment with efanesoctocog alfa for 26 weeks, followed by once-weekly prophylaxis for 26 weeks (group B), the annualized bleeding rate decreased when patients switched from on-demand treatment to prophylaxis (21.42 versus 0.69). (medpagetoday.com)
  • 1 Around the year 2000 it was reported that prophylaxis is most efficient when initiated early: before 3 years of age 2 or directly after the first joint bleed. (haematologica.org)
  • The present study assesses how the increasing awareness of the importance of early prophylaxis affected bleeding before prophylaxis, CVAD use, initial prophylactic regimens, and achievement of primary prophylaxis. (haematologica.org)
  • Methods: Platelet-poor plasmas were prepared from 16 severe FXI-deficient patients who were divided into bleeders or non-bleeders, based on bleeding associated with at least two tooth extractions without prophylaxis. (tau.ac.il)
  • A traumatic injury can lead to severe bleeding and become life threatening in a matter of minutes. (yahoo.com)
  • Tomonil 1.5 mg tablets can be used at any time during the menstrual cycle unless menstrual bleeding is overdue. (who.int)
  • Efforts to improve precircumcision screening are intended to reduce the occurrence of bleeding adverse events by identifying clients who might have signs of a bleeding disorder. (cdc.gov)
  • Variceal hemorrhage is not discussed in this article because the underlying mechanisms of bleeding are different and require different therapies. (medscape.com)
  • The underlying mechanisms of nonvariceal bleeding involve either arterial hemorrhage, such as in ulcer disease and mucosal deep tears, or low-pressure venous hemorrhage, as in telangiectasias and angioectasias. (medscape.com)
  • Upper head Intracranial hemorrhage - bleeding in the skull. (wikipedia.org)
  • Pain back again in abdomen, lower back & side Nausa feel like vomiting, especially after eating Am bleeding heavier then usual? (healthtap.com)
  • Heavier bleeding may be a sign of another condition or issue. (healthline.com)
  • Among the 19 bleeding adverse events reported, seven occurred in clients who were later confirmed to have a bleeding disorder or nonspecific/other hematologic abnormality. (cdc.gov)
  • In several cases, the bleeding adverse event revealed a previously undiagnosed or undisclosed bleeding disorder. (cdc.gov)
  • For the study, the researchers compared the likelihood a woman would be diagnosed with a new bleeding disorder up to one week and three months after being vaccinated with the same likelihood of diagnosis before vaccination. (substack.com)
  • If a bleeding disorder is suspected, consider Platelet function assay (PFA) 100 and von Willebrand screen. (rch.org.au)
  • People with severe liver disease, including advanced cirrhosis or liver failure, are at higher risk of bleeding esophageal varices. (healthline.com)
  • Don't immediately assume unusual bleeding after a Pap test is a sign of cancer. (healthline.com)
  • Bleeding or spotting after a Pap smear isn't unusual, even for people without infections, cancer, or other conditions. (healthline.com)
  • Nevertheless, a considerable number of bleeding catastrophes arise in emergency settings or unusual circumstances. (medscape.com)
  • Severe postoperative bleeding after PCNL is associated with renal puncture via the inferior calyx, multiple renal stones and solitary kidney stones. (archivesofmedicalscience.com)
  • Preliminary diagnoses were febrile and hemorrhagic syndrome with severe dehydration and anemia. (cdc.gov)
  • Bleeding along with signs of severe anemia (such as pale skin, weakness) should also be seen. (seattlechildrens.org)
  • Due to an uptick in mass shootings, terror attacks and national disasters, the US Government is calling on civilians to learn how to treat severe bleeding. (google.com)
  • The Valve Academic Research Consortium (VARC) has proposed a standardized definition of bleeding in patients undergoing transcatheter aortic valve interventions (TAVI). (123dok.net)
  • Methods and Results--Between August 2007 and April 2012, 489 consecutive patients with severe aortic stenosis were included into the Bern-TAVI-Registry. (123dok.net)
  • Postcoital bleeding is seen in anywhere from 5% to 25% of people with cervical ectropion . (yahoo.com)
  • If the injury is on the leg or arm, elevate the limb so that it is above the level of the heart to slow bleeding. (standardfirstaidtraining.ca)
  • Traumatic bleeding is caused by some type of injury. (wikipedia.org)
  • No bleeding, vomiting or abdominal cramps just loose stools. (healthtap.com)