• preimplantation
  • Mammalian preimplantation development involves two lineage specifications: first, the CDX2-expressing trophectoderm (TE) and a pluripotent inner cell mass (ICM) are separated during blastocyst formation. (pnas.org)
  • Significant gains have been made in our understanding of the major events of mouse preimplantation development, and recent discoveries have shed new light on the establishment of the three blastocyst lineages. (jci.org)
  • Here, we review what has been learned from the mouse about the major events of mammalian preimplantation development and discuss recent work that has shed new insight on how the three blastocyst lineages come to be established. (jci.org)
  • trophectoderm
  • Blastocysts are given a quality grade for each of the 3 components and the score is expressed with the expansion grade listed first, the inner cell mass grade listed second and the trophectoderm grade third. (drmalpani.com)