• Two commonly discussed types of human cloning are therapeutic cloning and reproductive cloning. (wikipedia.org)
  • Therapeutic cloning would involve cloning cells from a human for use in medicine and transplants. (wikipedia.org)
  • Two common methods of therapeutic cloning that are being researched are somatic-cell nuclear transfer and (more recently) pluripotent stem cell induction. (wikipedia.org)
  • these are the "holy grail" that would be useful for therapeutic or reproductive cloning. (wikipedia.org)
  • In therapeutic cloning, the blastocyst is not transferred to a womb. (eurostemcell.org)
  • Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
  • To date, no human embryonic stem cell lines have been derived using therapeutic cloning, so both these possibilities remain very much in the future. (eurostemcell.org)
  • One of the next preclinical steps, according to the authors, is to evaluate, in the lab, differentiated patient-specific human embryonic stem cell lines for immune-system tolerance, therapeutic efficacy and safety. (scienceblog.com)
  • Finally, and inexorably, a true professional scientist poses clearly challenging questions to his research colleagues, and to the scientific enterprise in general, about the dubious "scientific" justification for the current rush to clone human beings - for both "therapeutic" and for "reproductive" purposes. (lifeissues.net)
  • But he is equally concerned about the unethical aspects inherent in the rush to perform " therapeutic " human cloning research, including the abuses to all vulnerable human patients who would be required to participate in clinical trials. (lifeissues.net)
  • Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
  • A number of large biotech companies and scientists are looking toward stem cells as the basis for a therapeutic solution to cure such illnesses as blindness, diabetes and spinal cord injuries. (thefutureofthings.com)
  • 5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
  • Therapeutic cloning refers to the production of embryonic stem cells for medicinal reasons, for example regenerative medicine and tissue replacement. (geminigenetics.com)
  • Therapeutic cloning involves the creation of an early-stage embryo (blastocyst) and the removal of stem cells from the developing embryo. (geminigenetics.com)
  • Therapeutic Cloning - Use of a donor cell to create pluripotent stem cells suitable for growing tissues for implantation into the donor or other patient. (schlich.co.uk)
  • Before delving into the molecular biology and therapeutic potentials of induced pluripotent stem cells, it is crucial to provide foundational definitions and descriptions. (papersowl.com)
  • The capacity of stem cells to divide and differentiate along different pathways is necessary in embryonic development and also makes stem cells suitable for therapeutic uses. (ivy-way.com)
  • In January 2008, Dr. Andrew French and Samuel Wood of the biotechnology company Stemagen announced that they successfully created the first five mature human embryos using SCNT. (wikipedia.org)
  • The embryos were developed only to the blastocyst stage, at which point they were studied in processes that destroyed them. (wikipedia.org)
  • The Catholic Church has always held that stem-cell research and therapies are morally acceptable, as long as they don't involve the creation and destruction of human embryos. (archstl.org)
  • This should remove the ethical objections that some people have to harvesting from donated human embryos. (newscientist.com)
  • In what's reported as a world-first achievement , biologists have grown mouse embryo models in the lab without the need for fertilised eggs, embryos, or even a mouse - using only stem cells and a special incubator. (theconversation.com)
  • Are 'synthetic embryos' of humans on the horizon? (theconversation.com)
  • Researchers have grown 'human embryos' from skin cells. (theconversation.com)
  • The recent desperation to clone human embryos may be seriously undermining accepted ethical principles of medical research, with potentially profound wider consequences. (lifeissues.net)
  • TORONTO (CNS) - The international scientific body governing stem cell research is abandoning the absolute 14-day limit on culturing human embryos in the laboratory, putting pressure on Canada's law prohibiting the practice. (thetablet.org)
  • On May 26, the International Society for Stem Cell Research said it was relaxing the 14-day rule, which prohibited experiments on human embryos past 14 days of development in the lab. (thetablet.org)
  • Rather than replace or extend the limit, the ISSCR now believes studies proposing to grow human embryos beyond two weeks should be considered on a case-by-case basis, subject to several phases of review. (thetablet.org)
  • Recent experimentation that has cultured lab-grown monkey embryos for up to 20 days and the possibility of creating human-monkey chimeras - beings that contain genetic codes from two different species - has further pushed the envelope on embryonic stem cell research. (thetablet.org)
  • Stem cell technologies have been dogged by controversy because of objections over the morality of sacrificing human embryos to produce the first human embryonic stem cell lines. (schlich.co.uk)
  • Advances in the biotechnology industry have increased scientists' understanding of the human genome and enhanced their ability to genetically modify eggs, sperm, and human embryos. (nyu.edu)
  • [10] While one can consequently interpret Myriad in a way that limits the scope of the Act, it leaves open the question of the patentability of modified human gametes and embryos and the altered or synthetic gene sequencing which could potentially be encompassed within those gametes and embryos. (nyu.edu)
  • Independently of the gestational periods, the qualitative evaluation showed the initial wash-in phase from the first appearance of the uterine artery to the rapid distribution in embryonic vesicles or placenta to the progressive washout, whilst there was no enhancement of either embryos or fetuses in any bitch. (edu.au)
  • Moreover, most early-stage embryos that are produced naturally (that is, through the union of egg and sperm resulting from sexual intercourse) fail to implant and are therefore wasted or destroyed. (wikiquote.org)
  • First, while stem-cell experimentation could involve the creation of embryos with the express purpose of destroying them, this is not the only means available for obtaining embryos. (jewishvaluesonline.org)
  • Thus, there is broad halakhic (Jewish legal) agreement that stem cell research is permitted on "excess" embryos. (jewishvaluesonline.org)
  • Most (but not all) authorities would forbid the creation of embryos with the express purpose of killing them in the pursuit of stem cell research. (jewishvaluesonline.org)
  • The controversy over stem cell research is focused specifically on the use of stem cells taken from embryos. (jewishvaluesonline.org)
  • Stem cells are now being collected from human embryos . (howtoaccess.com)
  • How are stem cells harvested from embryos? (howtoaccess.com)
  • However, human embryonic stem cell (hESC) research is ethically and politically controversial because it involves the destruction of human embryos . (howtoaccess.com)
  • Embryonic stem cells - Stem cells derived from human embryos. (howtoaccess.com)
  • Does all stem cell research destroy embryos? (howtoaccess.com)
  • Therefore, the embryos used in stem cell research are human beings, and it is morally reprehensible to kill them in order to remove the cells. (howtoaccess.com)
  • When stem cells are obtained from living human embryos, the harvesting of these cells necessitates destruction of the embryos, which is controversial in the U.S. (howtoaccess.com)
  • The Catholic Church has become the leading voice against any form of human cloning and even against the creation of human embryonic stem-cell lines from 'excess' in vitro fertilization (IVF) embryos. (howtoaccess.com)
  • Four embryonic stem cell lines from human fetal somatic cells were derived from those blastocysts. (wikipedia.org)
  • In contrast, adult stem cells can only give rise to differentiated somatic cells of the particular tissue from which these cells originated (Can/Hematol 2008). (papersowl.com)
  • The methodology included inducing differentiated somatic cells with the primary genes responsible for embryonic stem cell potency. (papersowl.com)
  • It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
  • Although not technically feasible at this time, researchers expect that it is possible to clone stem cells from a patient's own somatic cells. (howtoaccess.com)
  • The National Institutes of Health defines a human embryo as "the developing organism from the time of fertilization until the end of the eighth week of gestation. (archstl.org)
  • These stem cells are genetically matched to the donor organism, holding promise for studying genetic disease. (eurostemcell.org)
  • A clone is an organism that is a genetic copy of an existing one. (who.int)
  • This is the most known form of cloning and involves creating a genetically identical replica of a whole organism. (geminigenetics.com)
  • The process of reproductive cloning involves the nucleus of a somatic (body) cell from a donor organism to be cloned being transferred into an egg cell whose nucleus (genetic material) has been removed. (geminigenetics.com)
  • Stem cell research is, in part, a quest to understand cellular differentiation, the process by which a human being develops from one fertilized cell into a multicellular organism composed of over 200 different cell types - for example muscle, nerve, blood cell, or kidney. (jcpa.org)
  • The related concept of Longevity Determination , however, is the result of a species-specific genomic expression during early development that positions the somatic tissues of an organism to survive long after its reproductive period has been completed. (agemed.org)
  • conversely, two blastocysts may fuse to form a single (chimeric) organism. (wikiquote.org)
  • XI - embryonic stem cells: embryonic cells that are capable of modifying the cells of any organism tissue. (hinxtongroup.org)
  • … "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)
  • Up to 14 days a human blastocyst - the earliest stage of fetal development - consists almost entirely of pluripotent cells, which are those that could develop into the constitutive elements of any organ in the human body. (thetablet.org)
  • Conversely, you and I are on an unstoppable trajectory of growing and decaying that is a hallmark of later fetal and born human life. (jewishvaluesonline.org)
  • Although the possibility of cloning humans had been the subject of speculation for much of the 20th century, scientists and policymakers began to take the prospect seriously in 1969. (wikipedia.org)
  • Many nations outlawed it, while a few scientists promised to make a clone within the next few years. (wikipedia.org)
  • In 2011, scientists at the New York Stem Cell Foundation announced that they had succeeded in generating embryonic stem cell lines, but their process involved leaving the oocyte's nucleus in place, resulting in triploid cells, which would not be useful for cloning. (wikipedia.org)
  • In 2013, a group of scientists led by Shoukhrat Mitalipov published the first report of embryonic stem cells created using SCNT. (wikipedia.org)
  • Scientists have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury. (scienceblog.com)
  • The work also moves scientists one step closer to the goal of transplanting healthy cells into humans to replace cells damaged by diseases such as Parkinson's and diabetes. (scienceblog.com)
  • From the 31 nuclear-transfer blastocysts, the scientists derived 11 stem cell lines. (scienceblog.com)
  • Swann hopes to be the first to harvest embryonic stem cells from human parthenogenetic blastocysts, but other scientists are trying different approaches. (newscientist.com)
  • Scientists use immortal human cell lines in their research to investigate how cells function in humans. (asu.edu)
  • While regarded by many top scientists as the Holy Grail of medicine, others consider embryonic stem-cell research sacrilegious. (thefutureofthings.com)
  • This policy is similar to that of other countries, including Israel, where scientists are funded by Government to study embryonic stem cells despite the aforementioned bioethical issue. (jcpa.org)
  • In the early 1980s, scientists began to exploit two major classes of stem cells: embryonic and non-embryonic, or adult stem cells. (papersowl.com)
  • Because the early stem cells have the ability to become any one of the hundreds of different kinds of human cells, scientists are working on research using these cells with the aim of creating therapies to treat a variety of diseases. (jewishvaluesonline.org)
  • Scientists are discovering that many tissues and organs contain a small number of adult stem cells that help maintain them. (howtoaccess.com)
  • Reproductive cloning would involve making an entire cloned human, instead of just specific cells or tissues. (wikipedia.org)
  • not only does it mimic the cell specification and layout of an early-stage body plan - including precursors of heart, blood, brain and other organs - but also the "support" cells like those found in the placenta and other tissues required to establish and maintain a pregnancy. (theconversation.com)
  • The ability of our body to regenerate some of its tissues is largely owed to the reserves of adult stem cells. (thefutureofthings.com)
  • Numerous biological components, including genes, cells, tissues, and even complete creatures like sheep, have been cloned by researchers, and now cat, dog and equine cloning is widely and reliably available via international companies such as our partner, ViaGen Pets & Equine. (geminigenetics.com)
  • Stem cell technologies promise to be the next transformative medical technology offering therapies for conditions and diseases that are currently beyond medical science by creating replacement or supplementary tissues for a patient. (schlich.co.uk)
  • Totipotent stem cells contain all the constituents necessary to produce a living being, given that these cells can supply all embryonic and extraembryonic tissues required for proper growth (Can/Hematol 2008). (papersowl.com)
  • In the normal course of gestation, these cells will divide and split off from one another to become every cell in the human body, forming the various organs and tissues. (jewishvaluesonline.org)
  • With the cloning of a sheep known as Dolly in 1996 by somatic cell nuclear transfer (SCNT), the idea of human cloning became a hot debate topic. (wikipedia.org)
  • It became a hot topic in 1996 when Dolly the sheep was cloned via a process called somatic cell nuclear transfer. (archstl.org)
  • Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
  • To produce Dolly, the cloned blastocyst was transferred into the womb of a recipient ewe, where it developed and when born quickly became the world's most famous lamb. (eurostemcell.org)
  • Dolly the sheep was cloned in 1996. (thetablet.org)
  • The cloning of 'Dolly The Sheep' in 1996 by the Rosalind Institute in Scotland, UK, is the most recognised example of reproductive cloning. (geminigenetics.com)
  • These ethical concerns have prompted several nations to pass laws regarding human cloning. (wikipedia.org)
  • In a Science "Policy Forum" related to the team's latest findings, David Magnus and Mildred Cho from Stanford University in Palo Alto, CA discuss international oversight and ethical issues in oocyte donation, including the need to promote realistic expectations of the outcomes of stem cell research. (scienceblog.com)
  • A trick that persuades human eggs to divide as if they have been fertilised could provide a source of embryonic stem cells that sidesteps ethical objections to existing techniques. (newscientist.com)
  • This could eliminate one of the main sources of ethical controversy in this research," says Bob Lanza, head of research at the cloning company Advanced Cell Technology in Worcester, Massachusetts. (newscientist.com)
  • Stem cells are at the forefront of medical research and incite some of the most controversial ethical and religious debates worldwide. (thefutureofthings.com)
  • The use of the technique of nuclear transfer for reproduction of human beings is surrounded by strong ethical concerns and controversies and is considered a threat to human dignity. (who.int)
  • This technique is surrounded by strong ethical concerns and is considered a threat to human dignity. (who.int)
  • Bioethics tends to be dominated by discourses concerned with the ethical dimension of medical practice, the organization of medical care, and the integrity of biomedical research involving human subjects and animal testing. (erudit.org)
  • Accounting for the work of Jacques Derrida, and with reference to Michel Foucault's deliberations about biopower, Cary Wolfe has rightly questioned the entrenched discursive features of bioethics as a discipline according to which the boundary between the human and the non-human remains "an ethical (non)issue" (Wolfe, 2009). (erudit.org)
  • Is it ethical to harvest stem cells? (howtoaccess.com)
  • While the Catholic Church has maintained opposition to in vitro fertilization and experimentation on the developing human fetus, what limits should be placed on science and how to enforce them have been debated since culturing humans in labs became possible in the 1970s. (thetablet.org)
  • Assisted reproductive techniques for canines: preservation of genetic material in domestic dogs [3] "Assisted reproductive techniques (ARTs), such as artificial insemination, in vitro fertilization, and cryopreservation of gametes/zygotes, have been developed to improve breeding and reproduction of livestock and for the treatment of human infertility. (edu.au)
  • Marking a vast leap in reproductive therapy, it became possible to isolate these human embryonic stem cells for reproductive purposes, such as in vitro fertilization. (papersowl.com)
  • A similar approach has yielded stem cells from parthenogenetic monkey blastocysts ( New Scientist print edition, 6 October 2001). (newscientist.com)
  • The Church also supports research and therapies using adult stem cells, which are cells that come from any person who has been born - including umbilical cord blood, bone marrow, skin and other organs. (archstl.org)
  • After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)
  • For example, stem cells could be generated using the nuclear transfer process described above, with the donor adult cell coming from a patient with diabetes or Alzheimer's. (eurostemcell.org)
  • however, there are also stem cells in the adult body. (thefutureofthings.com)
  • These adult stem cells are considered multipotent, having the ability to differentiate into different cell types, albeit with a more limited repertoire than embryonic stem cells. (thefutureofthings.com)
  • Adult stem cells can be used to accelerate bone or tendon healing , and they can induce cartilage progenitor cells to produce a better matrix and repair cartilage damage . (thefutureofthings.com)
  • Adult stem cells can be used to replace damaged heart-muscle cells and are used in practice today . (thefutureofthings.com)
  • The most common application of adult stem cells is probably the restoration of blood cells for patients with leukemia, and there are many more applications currently in practice. (thefutureofthings.com)
  • Contrary to popular belief, stem cells are present in the human body throughout life and are found in many adult organs. (jcpa.org)
  • That is to say, one type of stem cell may be capable of differentiating into all adult cell types, while another may only be capable of maturing into one specific somatic cell type. (papersowl.com)
  • On a macro scale, the two classifications of stem cells are embryonic and adult stem cells. (papersowl.com)
  • To delve further into the specifics, embryonic and adult stem cells fall into potency categories reflecting their ability to differentiate: totipotent, pluripotent, multipotent, and unipotent. (papersowl.com)
  • Using these definitions, embryonic stem cells can be classified as totipotent or pluripotent at different developmental stages and locations, whereas adult stem cells can be categorized as pluripotent, multipotent, or unipotent (Figure 1). (papersowl.com)
  • However, the crowning achievement arose in 2006 when researchers at Kyoto University discovered the necessary means to reprogram differentiated adult cells to possess embryonic stem cell-like functionality, as if reversing time itself. (papersowl.com)
  • These are the blood cell-forming adult stem cells found in bone marrow . (howtoaccess.com)
  • There are two main types of stem cells - adult and embryonic: Adult stem cells - Stem cells derived from living humans . (howtoaccess.com)
  • Next, oocytes with the patient's genetic material were allowed to grow to the blastocyst stage, an early stage of embryo development. (scienceblog.com)
  • Historically, sterilization procedures have varied in techniques, goals, and risks, but Sharp's method of vasectomy allowed restriction of a patient's reproductive functions without significantly affecting other bodily functions. (asu.edu)
  • 2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
  • 3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
  • 7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
  • 3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
  • Imagine a world in which human beings can be replicated using cloning. (visit-now.net)
  • human beings have developed innovative technologies to treat and cure disease, to enhance human living conditions, and to protect or improve the environment. (jcpa.org)
  • Claims that you could clone individual treatments of human beings to treat common diseases like diabetes, suggests you need a huge supply of human eggs. (wikiquote.org)
  • All things considered, contemporary biological insights inform us that human beings, like all species, actually are already polygenomic organisms, and for that reason, fundamental biological concepts such as 'individual' and 'species' deserve considerable nuance. (demul.nl)
  • Ethically, since eventually all such "research" will be applied to people, he cautions against the abuse of women "egg" donors, and against the premature use of vulnerable sick human patients for testing supposedly "patient-specific" stem cells in supposed "therapies", pointing to the obvious violations of standard international research ethics guidelines such clinical trials would necessarily entail. (lifeissues.net)
  • WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • WHA50.37, which states "the use of cloning for the replication of human individuals is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • In this experiment, the researchers developed a protocol for using SCNT in human cells, which differs slightly from the one used in other organisms. (wikipedia.org)
  • The stem cells could be studied in the laboratory to help researchers understand what goes wrong in diseases like these. (eurostemcell.org)
  • Before patient-specific stem cells can potentially be used in the clinic, a variety of issues must be addressed, the researchers emphasized. (scienceblog.com)
  • In addition, researchers must develop methods to efficiently direct the differentiation of embryonic stem cells to specific stable cell types. (scienceblog.com)
  • The Korean researchers who performed this stem cell research improved upon their protocols that yielded the first embryonic stem cell line from a cloned human blastocyst. (scienceblog.com)
  • From the 185 donated oocytes, endowed with the genetic material from a different person (or in one case, the same person), the researchers report development of 31 hollow balls of cells called "human nuclear-transfer blastocysts. (scienceblog.com)
  • The researchers generated these stem cell lines ten times more efficiently than in their 2004 Science study, using improved laboratory methods. (scienceblog.com)
  • This achievement, published in the journal Cell by a team led by researchers from the Weizmann Institute of Science in Israel, is a very sophisticated model of what happens during early mouse embryo development - in the stage just after implantation. (theconversation.com)
  • Researchers using these human embryo models, often called blastoids , have even been able to start to explore implantation in a dish, but this process is much more challenging in humans than it is in mice. (theconversation.com)
  • Those cells went on to become the first immortal human cell line, which the researchers named HeLa. (asu.edu)
  • Most researchers obtain embryonic stem cells from the inner mass of a blastocyst, an embryonic stage when a fertilized egg has divided into 128 cells. (jcpa.org)
  • To overcome this significant crisis, researchers are investigating various approaches involving direct xenotransplantation, organoids, decellularization, and recellularization, and more recently, organ bioengineering using blastocyst complementation (BC). (frontiersin.org)
  • Father Pacholczyk, who is teaching a course on bioethics and life issues at Kenrick-Glennon Seminary this semester, said it is very easy to depersonalize humans when they are in the earliest stages of life. (archstl.org)
  • The earliest stages of pregnancy are difficult to study in most animals. (theconversation.com)
  • This is the earliest stage of embryonic development just before the complex process of implantation , when a mass of cells attach to the wall of the uterus. (theconversation.com)
  • It has not yet been " ensouled " - and so is not yet a " person " - i.e., a human subject to be protected from abuse in experimentation. (lifeissues.net)
  • The Vatican document "Dignitas Personae" ("The Dignity of a Person") warns that certain recent developments in stem-cell research, gene therapy and embryonic experimentation violate moral principles and reflect an attempt by man to "take the place of his Creator. (thetablet.org)
  • It wasn't until over a decade later, in the late 1990s, that human-derived stem cells were propelled to the forefront of experimentation. (papersowl.com)
  • A few years ago, in an article in the The Times of London newspaper, the author, Michael Gove, made the following statement: "Embryonic stem-cell experimentation involves not just the destruction of human life but the creation of life with the specific intent to destroy it. (jewishvaluesonline.org)
  • Second, Michael Gove holds that embryonic experimentation represents the destruction of human life. (jewishvaluesonline.org)
  • Recognizing this trend, Congress passed section 33 of the America Invents Act ("AIA") [8] in 2011, resulting in, among other things, a prohibition on patents for inventions "directed to or encompassing a human organisms. (nyu.edu)
  • In biology , cloning is the process of producing similar populations of genetically identical individuals that occurs in nature when organisms such as bacteria , insects or plants reproduce asexually . (wikiquote.org)
  • Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
  • In 2004 and 2005, Hwang Woo-suk, a professor at Seoul National University, published two separate articles in the journal Science claiming to have successfully harvested pluripotent, embryonic stem cells from a cloned human blastocyst using SCNT techniques. (wikipedia.org)
  • Hwang claimed to have created eleven different patient-specific stem cell lines. (wikipedia.org)
  • In the prestigious American journal Science, he claimed that he had succeeded in cloning a human blastocyst, which is an embryo in its early developmental stages (Hwang et al. (asu.edu)
  • 2004). A year later, in a second Science article, he made the earth-shattering announcement that he had derived eleven embryonic stem cell lines using his cloning technique (Hwang et al. (asu.edu)
  • Father Tad Pacholczyk is convinced that embryonic stem cells will someday cure diseases. (archstl.org)
  • There are high hopes that stem cells, which can develop into many different cell types, could be used to treat a range of diseases. (newscientist.com)
  • The recovered stem cells can then be used in the treatment of diseases and to aid the recovery of injuries. (geminigenetics.com)
  • Stem cells offer the prospect of treatments for diseases and injuries that are currently beyond medical science. (schlich.co.uk)
  • Stem cells may underpin the next generation of pharmaceuticals, with even greater promise for successful treatment of diseases that are intractable or scarcely treatable now. (schlich.co.uk)
  • While there is a great deal published on the potential medical applications of stem cell research to treat or cure diseases such as diabetes, Alzheimer's disease, Parkinson's disease, cancer, and heart disease, much less has been published on the future impact of stem cell research in reproductive medicine. (jcpa.org)
  • One of the bad things about stem cells is that they have been over-hyped by the media in regard to their readiness for treating multiple diseases . (howtoaccess.com)
  • Millions of people suffer from end-stage refractory diseases. (frontiersin.org)
  • The use of various types of stem cells for research purposes to make disease "models" in the lab for regenerative medicine and for "therapies" to cure sick patients for diseases is constantly in the news. (lifeissues.net)
  • Similarly, when the fertilized egg divides from two cells into four cells, each of these four cells has the potential to individually form a human fetus. (jcpa.org)
  • The stem cells derived from the inner mass of a blastocyst lack the ability to form a fetus when implanted into a woman, but are self-renewing and can be maintained for long periods of time in the laboratory as undifferentiated stem cells. (jcpa.org)
  • … "human clone" means an embryo that, as a result of the manipulation of human reproductive material or an in vitro embryo, contains a diploid set of chromosomes obtained from a single - living or deceased - human being, fetus, or embryo. (hinxtongroup.org)
  • Developments in biotechnology have raised new concerns about animal welfare, as farm animals now have their genomes modified (genetically engineered) or copied (cloned) to propagate certain traits useful to agribusiness, such as meat yield or feed conversion. (wikiquote.org)
  • The term is generally used to refer to artificial human cloning, which is the reproduction of human cells and tissue. (wikipedia.org)
  • A blastocyst (cloned or not), because it lacks any trace of a nervous system, has no capacity for suffering or conscious experience in any form - the special properties that, in our view, spell the difference between biological tissue and a human life worthy of respect and rights. (wikiquote.org)
  • Collected MII oocytes were vitrified and divided into four groups: untreated, 10 mM caffeine (CA), 10 μM MG132 (MG), and 10 mM caffeine +10 μM MG132 (CA+MG). After warming, the MPF activity of oocytes and their blastocyst formation and implantation rates in the CA, MG, and CA+MG groups were much higher than those in the untreated group. (molcells.org)
  • If implantation of the embryo is not contemplated, embryonic human life is static. (jewishvaluesonline.org)
  • Currently, the procedure for isolating non-reproductive cells for the nuclear transfer method involves animal enzymes and serum. (scienceblog.com)
  • The single cell line generated in the 2004 Science paper resulted from nuclear transfer in which the oocyte and non-reproductive ("somatic") cell came from the same healthy female. (scienceblog.com)
  • 2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
  • More than 100 nuclear transfer procedures could be required to produce one viable clone. (wikiquote.org)
  • Analysis of the effectiveness of caffeine and MG132 for improving somatic cell nuclear transfer (SCNT) technology using cryopreserved eggs showed that supplementation did not improve the blastocyst formation rate of cloned mouse eggs. (molcells.org)
  • The advent of techniques to propagate animals by nuclear transfer, also known as cloning, potentially offers many important applications to animal agriculture, including reproducing highly desired elite sires and dams. (nationalacademies.org)
  • That's why Father Pacholczyk, director of education at the National Catholic Bioethics Center in Philadelphia, said that the efforts to help people understand the immorality of embryo reserch, including human cloning, must focus on humanizing the issue and appreciating our own embryonic origins, not just on the desired results of embryonic or other types of stem-cell research. (archstl.org)
  • A decade later, cloning came to the forefront in Missouri with the narrow passage of Amendment 2, a ballot initiative in 2006 that constitutionally protects embryonic stem-cell research and human cloning. (archstl.org)
  • What is cloning, and what does it have to do with stem cell research? (eurostemcell.org)
  • This form of cloning is unrelated to stem cell research. (eurostemcell.org)
  • She is the Vice President of the Australasian Society for Stem Cell Research, non-executive director of the National Stem Cell Foundation of Australia and a member of ethics and policy advisory committees for several national and international organisations including the International Society for Stem Cell Research. (theconversation.com)
  • And he also agrees that if we don't find global agreement on human cloning, "we can probably expect dire consequences for the future of biomedical research and its impact on society at large. (lifeissues.net)
  • As he has questioned the HFEA before, would not the use of vulnerable human patients in clinical trials be premature, dangerous, and unethical given the already acquired knowledge in the research community that such supposed "patient-specific" stem cells would most probably cause serious immune rejection reactions in these patients? (lifeissues.net)
  • I knew and had great respect for the famous Protestant theologian and bioethicist Paul Ramsey, and used much of his work concerning the use of human subjects in research in my own. (lifeissues.net)
  • Recent advances in the field of stem-cell research are giving hope to millions. (thefutureofthings.com)
  • A particular field encouraged by the foundation is stem-cell research, with the great hope that it will result in the ability to get cells to differentiate into neurons and support cells to bridge the gap of a spinal cord injury. (thefutureofthings.com)
  • Human embryonic stem cell research began in the 1990s. (thetablet.org)
  • In order to better appreciate the role of stem cell research in reproductive medicine, there is a need to understand the critical biological principles of stem cell research and its potential applications to medicine. (jcpa.org)
  • The destruction of the pre-embryo has been the critical issue in the U.S. behind imposing limits on federal government-sponsored research in embryonic stem cells. (jcpa.org)
  • In 2009, in a major reversal of U.S. policy, President Obama signed an executive order pledging to "vigorously support" embryonic stem cell research. (jcpa.org)
  • Think of mice with sizable pieces of genetic code that originated from the human genome, used in cancer and pharmaceutical research, or pigs with a human heart, that are grown for medical applications. (demul.nl)
  • Stem Cell Research? (jewishvaluesonline.org)
  • What is the Jewish perspective on stem cell research? (jewishvaluesonline.org)
  • If embryonic stem-cell research offers real possibilities for future cures then, from a Jewish point of view, it may be pursued with caution, humility, and strict supervision. (jewishvaluesonline.org)
  • Why is stem cell research controversial? (howtoaccess.com)
  • Stem cell research is legal in the United States, however, there are restrictions on its funding and use . (howtoaccess.com)
  • HESC research is morally wrong since it is the direct destruction of innocent human life and does not benefit the individual embryo undergoing the research (3). (howtoaccess.com)
  • What countries have banned stem cell research? (howtoaccess.com)
  • What religions are against embryonic stem cell research? (howtoaccess.com)
  • increased public sensitivity and awareness together with the development of national regulations of governance of human cloning and embryo research in general. (lifeissues.net)
  • An in-depth analysis aiming at re-defining this terminology according to the new developments in human embryo research would be highly beneficial . (lifeissues.net)
  • 3. National regulations of governance of human cloning and embryo research in general adopted so far confirm the convergence of views of the refusal to adopt legislation or guidelines permitting reproductive cloning , while they still show variations on the legitimacy of human cloning carried out as part of research agendas. (lifeissues.net)
  • Molecular cloning refers to the production of multiple copies of a DNA fragment or gene. (geminigenetics.com)
  • Unlike the male germline, the bulk of The synthesis of the aforementioned molecular oocytes do not have a gonial stem cell population. (gotomydoctor.com)
  • Asexual reproduction is a natural method used by certain plants, bacteria, and single-celled creatures to create genetically identical offspring, i.e. clones. (geminigenetics.com)
  • In the United States, most people are assigned both a biological sex and gender at birth based on their chromosomes and reproductive organs. (asu.edu)
  • The ICM continues to differentiate into three germ layers-ectoderm, mesoderm and endoderm, each of which follows a specific developmental destiny that takes them along an ever-specifying path at which end the daughter cells will make up the different organs of the human body. (thefutureofthings.com)
  • Continued development of new biotechnologies also will allow farm animals to serve as sources of both biopharmaceuticals for human medicine and organs for transplantation. (nationalacademies.org)
  • For those who hold this view, extracting stem cells from a blastocyst is as morally abhorrent as harvesting organs from a baby to save other people's lives. (howtoaccess.com)
  • The tricked eggs divide for four or five days until they reach 50 to 100 cells - the blastocyst stage. (newscientist.com)
  • It's the spark of life," says Swann, who has previously showed that the human version of the protein can trigger mouse eggs to develop into blastocysts. (newscientist.com)
  • Human eggs contain two sets of chromosomes, one of which is normally jettisoned within two hours of fertilisation. (newscientist.com)
  • In 2003, a team led by David Wininger, now at Wake Forest School of Medicine in North Carolina, grew parthenogenetic human blastocysts by stimulating eggs chemically ( New Scientist print edition, 26 April 2003). (newscientist.com)
  • Even if you don't have a religious view of the sanctity of life, you have to ask is there going to be a massive trade in human eggs from poor women to rich countries. (wikiquote.org)
  • Cryopreservation of mammalian oocytes has been successfully applied for long-term storage of surplus eggs in mammalian assisted reproductive technology (ART), including in humans. (molcells.org)
  • Thus if by "potential" one means "potency" - i.e., that the early human embryo already exists with a human nature that is already there, and has its own inherent power or capacity (provided by that human nature) to simply grow bigger and bigger through all the usual developmental stages through birth, then such a statement stands as accurate - both scientifically and philosophically. (lifeissues.net)
  • Many of these developmental abnormalities are common to human development. (edu.au)
  • To take human organ generation via BC and transplantation to the next step, we reviewed current emerging organ generation technologies and the associated efficiency of chimera formation in human cells from the standpoint of developmental biology. (frontiersin.org)
  • To be sure, viewed through the lens of Jewish law, even the embryo outside the womb is human life. (jewishvaluesonline.org)
  • Left outside the womb, there is not the slightest hope that it will become anything more than the embryonic life it currently represents. (jewishvaluesonline.org)
  • For example, the stem cells can differentiate into cells that display characteristics of skin and retina cells, muscle cell bundles, bone matrix cells and cells of the gastrointestinal and respiratory lining. (scienceblog.com)
  • As the embryonic cells divide and the daughter cells differentiate, they become increasingly specific. (thefutureofthings.com)
  • Oligopotent stem cells, though not often widely discussed, have the ability to differentiate into a few cells (Kara et al. (papersowl.com)
  • Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
  • Each of the 11 new human embryonic stem cell lines was created by transferring the nuclear genetic material from a non-reproductive cell of a patient into a donated egg, or "oocyte," whose nucleus had been removed. (scienceblog.com)
  • Oocyte donors and patients who donated non-reproductive cells were all unpaid volunteers. (scienceblog.com)
  • 7. "[footnote 16]: The cloning procedure supplies the oocyte with a complete set of chromosomes, all of which are contained in the nucleus which is transferred into the denucleated oocyte. (lifeissues.net)
  • a) Note, again, the reference to only sexual human reproduction - "the moment of conception" - i.e., fertilization. (lifeissues.net)
  • Thus, while Ramsey agreed that there is a human being present immediately at fertilization, he did not agree that it was also a human embryo or a human person - the classic "pre-embryo" argument. (lifeissues.net)
  • In the first 4 - 5 days after fertilization, the early-stage embryo (or blastocyst) is comprised of about 150 cells, within which there is a region called the Inner Cell Mass containing the stem cells. (jewishvaluesonline.org)
  • Embryonic stem cells are usually harvested shortly after fertilization (within 4-5 days) by transferring the inner cell mass of the blastocyst into a cell culture medium , so that the cells can be multiplied in a laboratory. (howtoaccess.com)
  • A pluripotent stem cell has the potential to form all cells of the embryo, but cannot form a placenta. (papersowl.com)
  • This pluripotency enables these cells to produce daughter cells of all differentiated somatic cell types, germ cells, and cells of all three embryonic germ layers (Can/Hematol 2008). (papersowl.com)
  • It's hard to find a simplified, but not overly simplified, explanation of how pluripotent or totipotent stem cells become germ cells, or any other cells for that matter, but it begins in the embryo. (ussromantics.com)
  • In this regard, emerging technologies of chimeric human organ production via blastocyst complementation (BC) holds great promise. (frontiersin.org)
  • The surrogate mum carries the cloned pet for the gestation period and once ready, gives birth to the clone who will be an identical genetic twin to the original pet whose skin sample was used to make the nucleus of the donor egg cell. (geminigenetics.com)
  • Reproductive Cloning - Use of a donor cell to create a new human genetically identical to the donor. (schlich.co.uk)
  • if you have a choice of starting material and are forced to use embryonic stem cells to carry out the invention, ensure you describe the use of embryonic stem cells from morally acceptable sources in your patent application. (schlich.co.uk)
  • It is important to grasp the full force of the claim that the embryo is morally equivalent to a person, a fully developed human being. (howtoaccess.com)
  • When the cloning process is used in this way, to produce a living duplicate of an existing animal, it is commonly called reproductive cloning. (eurostemcell.org)
  • Humans and other mammals may produce natural clones, commonly referred to as identical twins. (geminigenetics.com)
  • There are also naturally occurring clones among animal populations. (geminigenetics.com)
  • As well as their distinctive white markings and long curved horns, these cattle are special because they are now considered a herd of naturally occurring clones. (geminigenetics.com)
  • Every gene in the human body is encoded as deoxyribonucleic acid ("DNA"), and Myriad Genetics confronted the issue of whether a naturally occurring segment of DNA was eligible for patent. (nyu.edu)
  • The term stem cell can be defined by two very important qualities: the cell has the ability to self-renew and, in a more general sense, the cell has not completed differentiation into its final state. (thefutureofthings.com)
  • Cellular differentiation begins with the fertilized egg which serves as the identifying characteristic of an embryonic stem cell. (jcpa.org)
  • A stem cell commences as an undifferentiated cell that can either undergo self-renewal, whereby it generates daughter cells that remain as stem cells, or mature into a specific cell type via differentiation (Can/Hematol 2008). (papersowl.com)
  • Perhaps Ramsey would give other extraordinarily powerful arguments as to why human cloning is unethical, but he obviously would not be able to base it on his unscientific "pre-embryo" position. (lifeissues.net)
  • As a result, stem cell tourism has become a lucrative yet unethical business worldwide. (howtoaccess.com)
  • Originally the relevant philosophical term was "potency" (or inherent power or capacity conveyed by a specific nature) was used to apply to an already existing substance - such as a new living human embryo. (lifeissues.net)
  • The early mammalian embryo consists of the extra-embryonic cell layers-the trophoblast and a body of cells called the inner cell mass (ICM), which eventually become the embryo proper. (thefutureofthings.com)
  • The first hybrid human clone was created in November 1998, by Advanced Cell Technology. (wikipedia.org)
  • On closer inspection, the mythological human-animal combinations appear to contain more truth on this point than nineteenth-century biology, which was strongly driven by a separative cosmology, which still haunts common sense conceptions of life today. (demul.nl)
  • So Darwin never quite cracked the code of inheritance as we understand it today, but the work with plants which occupied his last years - allowing him to avoid the acrimony around human origins surrounding the publication of On the origin of species - produced important results for the understanding of plant reproductive biology. (ussromantics.com)
  • Canto: Right, but let's not get bogged down in the history of reproductive biology and the birth of genetics here, as it's hard enough for me to comprehend meiosis and mitosis, gametes and zygotes and all the rest, as we understand it all today. (ussromantics.com)
  • It is quite possible that the advances in human biology in the remainder of the twentieth century will be remembered as the most significant scientific achievement of the animal species known as Homo sapiens . (lifeissues.net)
  • In his speech on "Biological Possibilities for the Human Species of the Next Ten Thousand Years" at the Ciba Foundation Symposium on Man and his Future in 1963, he said: It is extremely hopeful that some human cell lines can be grown on a medium of precisely known chemical composition. (wikipedia.org)
  • Aging is a physical process that doesn't normally reveal itself until after the completion of a species-specific interval of reproductive competence during which adults rear their progeny from childhood to independence (See Life History ). (agemed.org)
  • CR has been effective in all species in which it has been tried (although the jury is still out on humans). (agemed.org)
  • Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)
  • a so-called synthetic embryo in a Petri dish will have its limitations on what it can teach us about human development, and we need to be conscious of that. (theconversation.com)
  • That is, it would be acknowledging that the human embryo and the human " baby " are the same human being and human person throughout all of his/her development. (lifeissues.net)
  • They are simply at different stages of that development. (lifeissues.net)
  • Overall, the presence of stem cells is essential for proper human development and function as they contribute to the growth, maintenance, and repair of numerous physiological systems (Kara et al. (papersowl.com)
  • These results suggest that maintaining MPF activity after cryopreservation may have a positive effect on further embryonic development, but is unable to fully overcome cryoinjury. (molcells.org)
  • It all begins at the beginning, during the early stages of male foetal development. (ussromantics.com)
  • This lack of potential for development puts embryonic human life in a separate category. (jewishvaluesonline.org)
  • 1. Cloning is an umbrella term traditionally used to describe different processes for duplicating biological material. (who.int)
  • The word "cloning" refers to a variety of procedures that may be used to create biological copies that are genetically identical to the original. (geminigenetics.com)
  • In addition, specific proteins or biological substances can be added to these stem cell cultures to transform them in the laboratory into a large variety of specialized cell types, such as nerve, liver, muscle, bone, and blood cells. (jcpa.org)
  • Additional biological facts suggest that a blastocyst should not be identified with a unique individual person, even if the argument that it lacks sentience is set aside. (wikiquote.org)
  • Cloning can in fact occur as a natural phenomenon. (geminigenetics.com)
  • As part of its charge, the committee was asked to prepare a subreport evaluating methods for detecting potential unintended compositional changes across the spectrum of messenger ribonucleic acid (mRNA), proteins, metabolites and nutrients that may occur in food derived from cloned animals that have not been genetically modified via genetic engineering methods. (nationalacademies.org)
  • Moreover, in Myriad Genetics , the Supreme Court found that an identical provision was inapplicable in a discussion on real and synthetic human genes, noting that the "Act does not even mention genes, much less isolated DNA. (nyu.edu)
  • We now see a patent landscape where stem cell technologies and related therapies can, with very few exceptions, be protected via patents, provided the appropriate form of claim wording is used. (schlich.co.uk)
  • A recent UNESCO draft document, although rather vague and deficient in itself, probably does the best job of at least initially identifying and describing some of these new reproductive technologies in relatively simple form, with a few generalized helpful sketches online. (lifeissues.net)
  • Because human-animal combinations are among us again, and this time not as creations of mythological imagination, but as products of contemporary biotechnology, such as cybrids and chimeras. (demul.nl)
  • Detailed descriptions of methods used in animal cloning and biotechnology are provided in the report Animal Biotechnology: Science-Based Concerns (NRC, 2002). (nationalacademies.org)