• Yet only those with mood disorders (depression and bipolar disorder) also produced more of a neurotoxic metabolite instead of an alternative neuroprotective one. (nature.com)
  • At the 2012 meeting of the American Academy of Child and Adolescent Psychiatry (AACAP) meeting, Anne Duffy and Gabrielle A. Carlson sponsored a symposium on the association between anxiety and minor mood disorders and subsequent bipolar disorder in those at high risk. (bipolarnews.org)
  • Researchers presenting at the symposium consistently found that there is a sequence in which young people at high risk for bipolar disorder develop increasingly severe illnesses: first anxiety, then mood disorders, then bipolar illness. (bipolarnews.org)
  • One difference: the incidence of childhood-onset bipolar disorders in those at high risk because a parent has the disorder was lower in Canada, Switzerland, and the Netherlands than it was in the US. (bipolarnews.org)
  • In her sample of Canadian patients , Duffy found that a sequence of developing anxiety and mood disorders seemed to predate the onset of bipolar disorder in those at high risk because a parent has bipolar disorder. (bipolarnews.org)
  • These were followed by minor mood disorders in adolescence, then major depression in late adolescence or early adulthood, and finally bipolar disorder. (bipolarnews.org)
  • This review also discusses implications and recommendations for future research regarding the HPA axis in the intergenerational transmission of depressive disorders. (umn.edu)
  • Additional information includes depression in children and teens, women, and African-Americans, as well as different types of depressive disorders, exploring myths about depression, treatments, and self-care strategies. (cscoreumass.org)
  • Provides information on depressive disorders, and how to cope with and treat symptoms. (cscoreumass.org)
  • Abnormal functional connectivity has been identified in individuals with schizophrenia, major depressive disorder, and bipolar disorder , according to a study published in the Journal of Affective Disorders . (psychiatryadvisor.com)
  • In the United States, mental health professionals diagnose bipolar disorder based on the symptoms outlined in the most recent edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). (psychcentral.com)
  • We want people without mood disorders to use the app as well so that we can better understand keystroke dynamics in healthy adults versus those with bipolar disorder. (differentbrains.org)
  • Aims: to measure the association between Celiac Disease (CD) and affective disorders, particularly Bipolar Disorder (BD), since it has not been studied yet, and to measure how much the quality of life (QoL) of a person with CD is affected by comorbidity with these disorders. (clinical-practice-and-epidemiology-in-mental-health.com)
  • In this Discussion, you analyze a case study focused on a depressive disorder or bipolar disorder using the steps of differential diagnosis.To prepare: View the TED Talk "Depression, the Secret We Share" (TED Conferences, LLC, 2013) and compare the description of Andrew Solomon's symptoms to the criteria for depressive disorders in the DSM-5. (achieverpapers.com)
  • Next review the steps in diagnosis detailed in the Morrison (2014) reading, and then read the case provided by your instructor for this week's Discussion, considering the client against the various DSM-5 criteria for depressive disorders and bipolar disorders.By Day 3Post a 300- to 500-word response in which you address the following:*Provide the full DSM-5 diagnosis for the client. (achieverpapers.com)
  • Bipolar disorder (BD) comprises a spectrum of different mood disorders, characterized by variable severity of illness, functional impairment, comorbidity patterns, suicidal risk, cognitive impairment, and treatment response (Akiskal et al. (springeropen.com)
  • Within the bipolar spectrum, BD type II (BD II) and I (BD I) are currently the main clinically defined expressions of BD, as acknowledged by the fifth edition of the diagnostic and statistical manual of mental disorders (DSM-5) (American Psychiatric Association 2013 ). (springeropen.com)
  • Self-Harm, Affective Traits, and Psychosocial Functioning in Adults With Depressive and Bipolar Disorders. (ox.ac.uk)
  • Since the DSM-5 was published in 2013, updates have been made to the codes for bipolar I and bipolar II disorders. (psychcentral.com)
  • Previous studies investigated predictors of repetitive transcranial magnetic stimulation (rTMS) response in depressive disorders but there is still limited knowledge about clinical predictors. (tmssolutions.com)
  • We performed a binary logistic regression analysis in 248 patients with depressive disorders (unipolar N=102, bipolar N=146) who received 20 sessions of DLPFC rTMS (High-frequency rTMS, low-frequency rTMS, bilateral rTMS) to investigate significant clinical and demographic predictors of rTMS response. (tmssolutions.com)
  • Findings are based on the largest thus far reported sample of patients with depressive disorders that received DLPFC rTMS. (tmssolutions.com)
  • To qualify for a bipolar disorder diagnosis, a person must meet the criteria in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition, text revision ( DSM-5-TR ). (medicalnewstoday.com)
  • This refers to other disorders that are similar to bipolar but do not meet diagnostic criteria because the episodes are too short or not severe enough. (medicalnewstoday.com)
  • The use of the fluorescent Ca ++ probe fura-2 in human platelets provides a useful method to investigate the mechanism of lithium's action in bipolar disorder and to study Ca ++ related systems which may be abnormal in bipolar disorders. (elsevierpure.com)
  • Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults in short-term studies with major depressive disorder (MDD) and other psychiatric disorders. (drugs.com)
  • Mental, neurological and substance use disorders include common mental health conditions such as depressive and anxiety disorders, severe mental disorders including schizophrenia and bipolar disorder and, common among children, conduct disorders, attention deficit hyperactivity and developmental disorders. (who.int)
  • Manic-depressive illness: bipolar disorders and recurrent depression 2nd ed. (bvsalud.org)
  • Many people with bipolar I disorder experience hypomanic and depressive episodes, too. (psychcentral.com)
  • There's a large community out there of people living with bipolar disorder, each with unique experiences. (psychcentral.com)
  • By understanding and recognizing these manic and depressive traits, it becomes easier to comprehend the challenges faced by those living with bipolar disorder. (mentalhealthblurb.com)
  • The researchers found that people with major depressive disorder, bipolar disorder and schizophrenia all showed a shift in tryptophan metabolism from serotonin to the kynurenine pathway. (nature.com)
  • Our objective was to examine and compare mortality rates after admission with schizophrenia, schizoaffective disorder, unipolar depressive disorder, or bipolar affective disorder and to examine the impact of family history of psychiatric admission on mortality. (nih.gov)
  • This single-site study included 126 individuals with schizophrenia, 97 with bipolar disorder, 126 with major depressive disorder, and 188 in a healthy control group, all of whom were administered functional magnetic resonance imaging in resting state. (psychiatryadvisor.com)
  • Schizophrenia was associated with the highest degree of alterations, followed by bipolar disorder and then by major depressive disorder. (psychiatryadvisor.com)
  • Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorder. (cdc.gov)
  • Cardiovascular disease (CVD) risk factors are common among patients with serious mental illnesses (SMI) such as schizophrenia, schizoaffective disorder, and bipolar disorder (1-7). (cdc.gov)
  • All types of bipolar disorder respond well to treatment. (psychcentral.com)
  • Researchers have identified several types of bipolar disorder, with each affecting mood in different ways. (medicalnewstoday.com)
  • There are two primary types of bipolar disorder: Bipolar I and Bipolar II. (psychologytoday.com)
  • There are 2 types of bipolar disorder, bipolar 1 and bipolar 2. (msdmanuals.com)
  • Bipolar disorder is a serious mental disease marked by episodes of depression, mania, hypomania, or mixed states. (physiciansweekly.com)
  • In some cases, individuals may experience milder forms of mania, known as hypomania, or less severe depressive symptoms, termed dysthymia. (mentalhealthblurb.com)
  • The different mood states associated with bipolar disorder are depression, hypomania and mania. (blogspot.com)
  • Bipolar II disorder refers to repeated episodes of depression and a milder bipolar disorder symptom called hypomania. (blogspot.com)
  • Episodes of the hypomania type of bipolar disorder symptom are not complicated by psychosis-related symptoms. (blogspot.com)
  • People with bipolar II normally have a major depressive episode that lasts at least two weeks along with hypomania , a mania that is mild to moderate and does not normally require hospital care. (psychologytoday.com)
  • In bipolar disorder type II, there has to be episodes of hypomania that are also then accompanied by depressive episodes. (medscape.com)
  • The diagnostic reliability of bipolar disorder tends to be higher (at least of mania) than unipolar depression, but the diagnostic reliability of hypomania is relatively low. (medscape.com)
  • However, until mania or hypomania occurs, a diagnosis of bipolar disorder would be premature. (medscape.com)
  • Repeated episodes of hypomania or mania only are classified as bipolar. (who.int)
  • It is similar to bipolar disorder but is less severe and less frequent. (medicalnewstoday.com)
  • Across both diagnoses, histories of self-harm were related to lower levels of current global functioning, more severe depressive symptoms, and high self-reported emotional dysregulation and neuroticism. (ox.ac.uk)
  • Bipolar disorder symptoms for the manic phase may include severe mood changes, exaggerated self-esteem, increased energy levels, decreased need for sleep, increased talking, distractibility, hypersexuality, increased activity and excessive involvement in risky behaviors. (blogspot.com)
  • People with bipolar I have had at least one manic episode, which may be very severe and require hospital care. (psychologytoday.com)
  • People with bipolar disorder experience severe depression or have low energy for several days or weeks. (medlineplus.gov)
  • Bipolar depression may have more severe anhedonia, hypersomnia, and psychomotor slowing-"melancholic" types of variants. (medscape.com)
  • Unipolar depressive disorder, bipolar affective disorder, and schizoaffective disorder were associated with the same pattern of excess mortality. (nih.gov)
  • The prevalence of lifetime self-harm was higher in patients with bipolar disorder compared with patients with a unipolar depressive disorder. (ox.ac.uk)
  • Self-harm was also more strongly linked to impulsivity in individuals with bipolar disorder compared with unipolar depressive disorder. (ox.ac.uk)
  • Objective: To evaluate the prevalence and the predictors of depressive switch in patients with bipolar I disorder (BD-I) requiring the initiation or change (but not a dose change) of treatment with oral antipsychotics or mood stabilizers for mania or mixed-mania. (psychiatrist.com)
  • Further randomized controlled studies are needed to confirm possible predictors of a depressive switch during mania. (psychiatrist.com)
  • It is difficult to distinguish between bipolar disorder and major depressive disorder (MDD) in patients lacking a clear history of mania. (psychiatrist.com)
  • Patients were divided into two groups according to their first episode of bipolar disorder, either depression or mania. (physiciansweekly.com)
  • Having one episode of mania is enough for you to receive a diagnosis of bipolar I disorder. (psychcentral.com)
  • In most people with bipolar disorder, there is no clear cause for the periods (episodes) of extreme happiness and high activity or energy (mania) or depression and low activity or energy (depression). (medlineplus.gov)
  • Bipolar disorder is when someone experiences periods of extreme emotional highs (mania) and lows (depression). (medicalnewstoday.com)
  • Bipolar disorder is a psychiatric illness which refers to a person's mood swings from mania to depression. (blogspot.com)
  • Bipolar I disorder is described as a condition wherein a patient experiences periods of mania alternating with periods of depression wherein patients experience simultaneous occurrence of manic and depressive symptoms called mixed states. (blogspot.com)
  • However, unlike with major depression, people with bipolar depression can also experience mania, which causes feelings of joy and euphoria. (medicalnewstoday.com)
  • But bipolar disorder causes distinct cycles in mood that change from depression to mania. (medicalnewstoday.com)
  • Bipolar disorder, also known as manic depression , is a chronically recurring condition involving moods that swing between the highs of mania and the lows of depression. (psychologytoday.com)
  • The defining feature of bipolar disorder is mania. (psychologytoday.com)
  • But while an episode of mania is what distinguishes bipolar disorder from depression, a person may spend far more time in a depressed state than in a manic or hypomanic one. (psychologytoday.com)
  • Bipolar disorder is a mental disorder that has periods of depression and periods of mania. (msdmanuals.com)
  • Type I bipolar disorder is defined by the occurrence of mania and cannot be diagnosed in the absence of mania. (medscape.com)
  • In contrast to that, a family history of bipolar disorder in someone who is young and developing recurrent depressive episodes might suggest that this may be a bipolar individual. (medscape.com)
  • Lithium-responsive patients tended to be those without anxiety disorder and substance abuse and who had classic bipolar episodes and clear well intervals between episodes. (bipolarnews.org)
  • If a child developed an anxiety disorder, they were three times more likely to develop bipolar disorder. (bipolarnews.org)
  • Axelson found a high incidence of anxiety disorder comorbidity in the offspring of bipolar parents, particularly generalized anxiety disorder and panic disorder. (bipolarnews.org)
  • Check out the International Bipolar Foundation and the Depression and Bipolar Support Alliance to find support groups, resources, and more. (psychcentral.com)
  • If both parents have bipolar disorder their offspring have a 25% risk of developing bipolar disorder and a 35% incidence of developing any affective disorder (although other data by Lapalme et al. (bipolarnews.org)
  • Lithium is an effective drug in the treatment of both manic and depressive episodes of bipolar disorder. (elsevierpure.com)
  • Nonetheless, because of this high heritability, environmental factors are probably less important, at least in the initiation of episodes of bipolar illness, including depression. (medscape.com)
  • In general, the depressive episodes of bipolar individuals and unipolar individuals look very similar. (medscape.com)
  • Patients were assessed at baseline and at follow-up visits by a variety of measures, including the Clinical Global Impressions scale for use in bipolar illness (CGI-BP). (psychiatrist.com)
  • Frequently, when the illness first appears, both manic and depressive phases might be somewhat mild. (jrank.org)
  • Duffy, a professor of psychiatry in Calgary, noted that bipolar disorder is highly heritable even though most adults with bipolar illness do not have a family history of bipolar illness among their first-degree relatives. (bipolarnews.org)
  • As expected, the incidence of any mood disorder was much higher in the offspring of parents with bipolar illness or major depression. (bipolarnews.org)
  • In contrast to the previous studies that were performed outside of the US, Axelson's study found significantly higher incidence of bipolar disorder in the offspring of bipolar parents compared to controls, with an illness on the bipolar spectrum (bipolar 1, bipolar 2, or bipolar not otherwise specified (NOS)) occurring in 18.7% of the offspring of parents with bipolar disorder. (bipolarnews.org)
  • Among recovered patients, BD II was associated with 6/25 (24.0%) baseline unfavorable illness characteristics/mood symptoms/psychotropics and hastened depressive recurrence ( p = 0.015). (springeropen.com)
  • Among depressed patients, BD II was associated with 8/25 (33.0%) baseline unfavorable illness characteristics/mood symptoms/psychotropics, but only non-significantly associated with delayed depressive recovery. (springeropen.com)
  • The story centers on a mother who struggles with worsening bipolar disorder and the effects that managing her illness has on her family. (wikipedia.org)
  • At first, bipolar disorder may be mistaken as another problem other than mental illness. (blogspot.com)
  • Ilardi, 41, argues that depression has become epidemic - "One in five Americans have experienced an episode of major depressive illness," he said - because our brains and bodies aren't designed for our 21st century lifestyles. (ljworld.com)
  • Lithium is most commonly used, however, as the treatment of choice for recurrent bipolar disorder (manic-depressive illness). (cdc.gov)
  • While bipolar disorder is a lifelong illness, medication and talk therapy can help people manage it and lead healthy lives. (medlineplus.gov)
  • That said, there are some types of presentations that are suggestive of an evolving or emerging bipolar illness. (medscape.com)
  • Disruptive Mood Dysregulation Disorder Fact Sheet- Information about a new disorder definition in the DSM-5 that is designed to reduce over-diagnosis and over-treatment of bipolar disorder in children. (cscoreumass.org)
  • Publication on bipolar disorder in youth, covering many topics such as causes, symptoms, diagnosis, and treatment for the disorder. (cscoreumass.org)
  • You may receive this diagnosis if you've had bipolar-like symptoms for at least 2 years, but your symptoms don't quite meet the criteria for bipolar disorder. (psychcentral.com)
  • In children , the bipolar-equivalent diagnosis is disruptive mood dysregulation disorder . (psychcentral.com)
  • If you've given your patient a bipolar disorder diagnosis , it may be helpful to provide them with additional resources for use outside your sessions. (psychcentral.com)
  • CONCLUSION: Metabolic components were significantly associated with the presence of depressive symptoms, independently of the diagnosis. (mcmaster.ca)
  • It is crucial to note that not all individuals with bipolar disorder experience extreme highs or lows with every episode. (mentalhealthblurb.com)
  • [ 3 ] Bipolar disorder is the most heritable condition in psychiatry. (medscape.com)
  • Differences in Demographic and Clinical Characteristics of Patients With Depressive vs. Manic First Episode of Bipolar Disorder. (physiciansweekly.com)
  • The aim of this study is to compare demographic and clinical variables based on a patient's first episode of bipolar disorder, including risk of recurrence over a 2-year period. (physiciansweekly.com)
  • These data of a cohort of Chinese patients add to the growing international literature on the relationship between index episode of bipolar disorder and clinical variables and outcomes. (physiciansweekly.com)
  • Doctors diagnose bipolar I after at least one manic episode. (psychcentral.com)
  • Doctors diagnose bipolar II after at least one depressive episode and at least one hypomanic episode. (psychcentral.com)
  • Bipolar disorder symptoms differ between people, and they might differ from one mood episode to the next. (psychcentral.com)
  • Bipolar disorder (BD) is a chronic, frequently comorbid condition characterized by high rates of mood episode recurrence and suicidality. (springeropen.com)
  • Little is known about prospective longitudinal characterization of BD type II (BD II) versus type I (BD I) in relation to time to depressive recurrence and recovery from major depressive episode. (springeropen.com)
  • Nevertheless, mood episode recurrences were found to occur in approximately half of bipolar patients within 2 years (Vazquez et al. (springeropen.com)
  • Among mood episode recurrences, there is a well-established predominance of depressive, compared with hypomanic/manic/mixed episodes, over the course of BD, with a subsequent overall greater burden in terms of economic costs, functioning, caregiver burden, and suicide (Judd et al. (springeropen.com)
  • 2014 ). For instance, a Systematic Treatment Enhancement Program for BD (STEP-BD) report showed that, among the 58% of patients who recovered from a syndromal mood episode at enrollment, approximately half had mood episode recurrence within 2 years, with twice as many depressive compared to mood elevation recurrences (Perlis et al. (springeropen.com)
  • More recently, in a systematic comparison of naturalistic studies versus randomized controlled trials, recurrence rates in BD were found to be substantial and similar, with first-episode recurrence-polarity being more often depressive than mood elevation (Vázquez et al. (springeropen.com)
  • 2006 ). Therefore, the frequency and severity of depressive recurrences in BD highlight the importance to identify clinical variables associated with hastened depressive recurrence (i.e., shorter time to next major depressive episode) in order to devise more effective disease management strategies. (springeropen.com)
  • Bipolar II disorder, defined by a minimum of one hypomanic episode and one major depressive episode, has only one diagnostic code. (psychcentral.com)
  • This means a person has had at least one manic episode, with or without a depressive episode. (medicalnewstoday.com)
  • Previous research suggests that at least 60% of adults with bipolar disorder report experiencing at least one stressful event in the months before a manic or depressive episode. (medicalnewstoday.com)
  • A major depressive episode may or may not accompany bipolar I, but does accompany bipolar II. (psychologytoday.com)
  • It can be the triggering episode of the disorder, followed by a depressive episode, or it can first manifest after years of depressive episodes. (psychologytoday.com)
  • OBJECTIVE: To assess the differences in the prevalence of the metabolic syndrome (MetS) and their components in young adults with bipolar disorder (BD) and major depressive disorder (MDD) in a current depressive episode. (mcmaster.ca)
  • Depressive episode (bipolar or unipolar) was assessed using the Mini International Neuropsychiatric Interview - Plus version (MINI Plus). (mcmaster.ca)
  • Higher levels of glucose, total cholesterol and LDL cholesterol, Body Mass Index, low levels of HDL cholesterol, and a higher prevalence of abdominal obesity were observed in both BD and MDD individuals with current depressive episode compared to the general population. (mcmaster.ca)
  • What is a depressive episode? (medlineplus.gov)
  • This is known as a depressive episode. (medlineplus.gov)
  • During a manic episode, people with bipolar disorder find it hard to focus at home, school, or work. (medlineplus.gov)
  • bipolar disorder, single manic episode (F30. (who.int)
  • Manic episodes, also known as manic highs, are the defining feature of bipolar disorder. (mentalhealthblurb.com)
  • Interestingly, there was a low and nonsignificant difference in the incidence of bipolar disorder, with 3.6% occurring in the offspring of parents with bipolar disorder, 2.7% in the offspring of parents with a major depressive disorder, and 0% of the controls. (bipolarnews.org)
  • There were few studies focused on offspring of parents with bipolar disorder. (umn.edu)
  • According to the National Institute of Mental Health, 4.4% of adults in the United States will experience bipolar disorder at some point in their lives. (medicalnewstoday.com)
  • About 2.8 percent of American adults have had bipolar disorder in the past year, according to the National Institute of Mental Health, and 4.4 percent experience bipolar disorder at some time in their lives. (psychologytoday.com)
  • The depressive phase include the following bipolar disorder symptoms: persistent sadness or irritability, loss of interest in certain activities, substantial changes in eating habits, sleeping problems, physical agitation, loss of vitality, and social withdrawal. (blogspot.com)
  • There is no single characteristic that distinguishes bipolar depression from other types of depression. (medicalnewstoday.com)
  • The average age that people develop bipolar disorder is 25 years old . (psychcentral.com)
  • The Bipolar Disorder Resource Center provides information about bipolar disorder in children and adolescents with links to additional information for parents and educators. (cscoreumass.org)
  • A preliminary composite of blood-based biomarkers to distinguish major depressive disorder and bipolar disorder in adolescents and adults. (bvsalud.org)
  • Patients with bipolar disorder may present with different symptoms at first onset. (physiciansweekly.com)
  • In our study, there are a number of differences in demographic and clinical characteristics of patients with different onset syndromes of bipolar disorder. (physiciansweekly.com)
  • However, research has not established that stress or trauma directly cause the onset of bipolar disorder or its mood cycles. (medicalnewstoday.com)
  • this work, which focused primarily on assessing individual-level interventions for clinical management of psychosis, bipolar disorder and depression, has been published in peer-reviewed literature and widely disseminated. (who.int)
  • Fast Five Quiz: Major Depressive Disorder - Medscape - Jun 16, 2023. (medscape.com)
  • Symptoms of Bipolar DisorderDepression Vs. Being A "typical" Teenager, Are You Depressed? (jrank.org)
  • According to statistics, two out of three times doctors initially fail to recognize the symptoms of bipolar disorder. (jrank.org)
  • DBSA), encourages people with depressive symptoms of bipolar disorder and major depressive disorder (also called depression) to share their stories of success. (medicaldesignandoutsourcing.com)
  • What are the symptoms of bipolar disorder? (msdmanuals.com)
  • Electroconvulsive therapy (ECT) may be used to treat the manic or depressive phase if it does not respond to medicine. (medlineplus.gov)
  • Bipolar disorder affects about 5.7 million adult Americans, which is 2.6% of the adult population, according to the National Institute of Mental Health. (differentbrains.org)
  • Bipolar disorder affects men and women equally. (medlineplus.gov)
  • Bipolar disorder affects 1% to 2% of the U.S. population. (medlineplus.gov)
  • Other bipolar disorder symptoms of this phase include high physical and mental energy and the incapability of the person affected to perceive that the moods and behaviors are abnormal. (blogspot.com)
  • The duration of elevated moods and the frequency with which they alternate with depressive moods can vary enormously from person to person. (psychologytoday.com)
  • The moods are known as manic and depressive episodes. (medlineplus.gov)
  • When you have bipolar disorder, you experience frequent mood swings-from extreme lows to extreme highs. (medlineplus.gov)
  • Bipolar disorder usually starts in people's teens or early adulthood. (medlineplus.gov)
  • A mood disorder was diagnosed in 34.5% of the offspring of the bipolar parents and 25.5% of the offspring of the parents with a major depressive disorder, and only 12.6% of controls. (bipolarnews.org)
  • The purpose of the present study was to construct a preliminary diagnostic model to distinguish major depressive disorder (MDD) and bipolar disorder (BD) using potential commonly tested blood biomarkers . (bvsalud.org)
  • Imaging studies of major depressive disorder have reported structural and functional abnormalities in a variety of spatially diverse brain regions. (psychiatryonline.org)
  • A total of 92 publications reporting 152 experiments were identified, collectively representing 2,928 patients with major depressive disorder. (psychiatryonline.org)
  • Major depressive disorder is the single largest contributor to disability worldwide, affecting as many as 300 million people annually ( 1 ). (psychiatryonline.org)
  • A stepwise backward logistic regression model was used to explore the effect of clinical variables on the occurrence of depressive switch. (psychiatrist.com)
  • Prevalence and clinical correlates of bipolar subtype in recovered (euthymic ≥8 weeks) and depressed patients were assessed. (springeropen.com)
  • Research on bipolar subtype relationships with depressive recurrence/recovery is warranted to enhance clinical management of BD patients. (springeropen.com)
  • Combined, bipolar disorder and depression affect as many as 22 million American adults(1,2,3,4) and, in a clinical study, nearly 2 out of 3 people with depression experience unresolved symptoms after initial antidepressant treatment. (medicaldesignandoutsourcing.com)
  • Bipolar disorder is a complex and chronic mental health condition that affects millions of people worldwide. (mentalhealthblurb.com)
  • The extreme mood swings caused by bipolar disorder can be quite harmful when left unchecked, so the early warning system offered by BiEffect is aimed at helping people with bipolar disorder to control and reduce extreme behavior more effectively. (differentbrains.org)
  • People who are suffering from the bipolar disorder symptoms repeatedly experience dramatic mood swings either within a day of over several months. (blogspot.com)
  • Also, when manic-depressives are in a milder manic phase-full of happiness, energy, and confidence- they and the people around them never stop to think that anything is wrong. (jrank.org)
  • Our results suggest an association between the depressive switch and treatment with both first- and second-generation antipsychotics, depressive-predominant polarity, greater severity of the symptomatology, and older age at evaluation. (psychiatrist.com)
  • Kaplan-Meier analyses assessed the relationships between bipolar subtype and longitudinal depressive severity, and Cox proportional hazard analyses assessed the potential mediators. (springeropen.com)