• The reaction of geranyl pyrophosphate with isopentenyl pyrophosphate results in the 15-carbon farnesyl pyrophosphate (FPP), which is an intermediate in the biosynthesis of sesquiterpenes such as farnesene. (wikipedia.org)
  • The terpenoids , also known as isoprenoids , are a class of naturally occurring organic chemicals derived from the 5-carbon compound isoprene and its derivatives called terpenes , diterpenes , etc. (wikipedia.org)
  • Cafestol and kahweol are present in high concentrations (up to 18% diterpene esters) in the oil derived from coffee beans. (gerli.com)
  • Cafestol (CAF) and kahweol (KAH) are two diterpenes found exclusively in the Coffea genus. (bvsalud.org)
  • Ent-kaurene is the ubiquitous precursor for gibberellin biosynthesis in plants, but it also serves as an intermediate in specialized (i.e., secondary) diterpenoid metabolism that leads to a diversity of more than 1,000 different metabolites. (bvsalud.org)
  • The diterpenes have exceptionally open chain, as found in geranylgeraniol or phytol which forms a part of chlorophyll and the side chain of vitamin E and K , and crocetin which is a diacid diterpenoid and the lipid part of the crocins, glycosylated derivatives present in saffron. (gerli.com)
  • In addition to common six-membered ring systems such as the ones found in zingiberene and bisacurone, cyclization of one end of the chain to the other end can lead to macrocyclic rings such as humulene. (wikipedia.org)
  • While indole diterpene (IDT) and rarely indole sesquiterpene (IST) pathways have been found individually in filamentous fungi, here we show that both cluster types are encoded within the genome of Tolypocladium album. (bvsalud.org)
  • We explored the biosynthesis of a bacterial trans-eunicellane natural product, albireticulone A (3), and identified a novel isomerase that catalyzes cryptic isomerization in the biosynthetic pathway. (bvsalud.org)
  • Nutraceutical effects on human health attributed to diterpenes include antioxidant, anticarcinogenic, and anti-inflammatory properties. (bvsalud.org)
  • CONCLUSION: This study managed to identify, for the first time, six diterpenes from the resin of P. pinaster, with anti-inflammatory, analgesic, and antibacterial activity. (bvsalud.org)