• Principal pathway of flavonid biosynthesis and related Myb transcription factors in grape. (scirp.org)
  • 13 C-tracing verified de novo biosynthesis of valine and further revealed build-up of pathway intermediate 2,3-dihydroxy-3-isovalerate. (elifesciences.org)
  • The sweetness is due to steviol glycosides, the glucosylated steviol derivatives of steviol glycoside biosynthesis pathway. (scialert.net)
  • In present study, we analyzed the effect of varying sucrose (1, 3 and 5%) concentrations on the genes involved in steviol glycoside biosynthesis pathway and content of steviol glycosides. (scialert.net)
  • Present work thus suggests that sucrose might be acting as an enhancer of transcriptional trigger to the genes of steviol glycoside biosynthesis pathway that could positively manipulate the production of steviol glycosides. (scialert.net)
  • Steviol glycoside biosynthesis pathway has sixteen steps catalyzed by different enzymes. (scialert.net)
  • The next four steps share similarity with gibberellic acid biosynthesis pathway. (scialert.net)
  • Presence of two functional copies of these genes has suggested their efficient role in steviol glycoside biosynthesis pathway as well. (scialert.net)
  • The rest five downstream steps are specific for steviol glycoside biosynthesis pathway. (scialert.net)
  • RESULTS: Combining in vivo labelling studies, differential expression analysis of transcriptome data and functional characterisation of insect genes in a yeast expression system, we reveal the biosynthetic pathway and identify the desaturase and reductase enzymes involved in the biosynthesis of. (lu.se)
  • RESULTS: Combining in vivo labelling studies, differential expression analysis of transcriptome data and functional characterisation of insect genes in a yeast expression system, we reveal the biosynthetic pathway and identify the desaturase and reductase enzymes involved in the biosynthesis of the main pheromone component (9Z,11E)-hexadecadienal, and minor components hexadecanal, (9Z)-hexadecenal and (11Z)-hexadecenal. (lu.se)
  • By using single-cell analyses, the scientists were able to discover new genes important for biosynthesis and show that the intermediates of the metabolic pathway accumulate in specific cell types. (hortidaily.com)
  • This resulted in reprogramming the steroidogenic pathway toward inactivation of 3-beta-hydroxysteroid dehydrogenase type 2 (HSD3B2), increased CYB5A expression, and increased biosynthesis of dehydroepiandrosterone ( DHEA ), 3 key features of zR maturation during adrenarche . (bvsalud.org)
  • The researchers predict that this methodological approach will provide important new insights into the biosynthesis of many other natural products from the plant kingdom. (hortidaily.com)
  • Dr. Williams is a decorated chemist and is well-known for his innovative work in polyketide biosynthesis, the development of enzymatic tools for protein engineering, and the development of novel biosensors to guide metabolic engineering and high-throughput synthetic biology. (biospace.com)
  • Protein Biosynthesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • This graph shows the total number of publications written about "Protein Biosynthesis" by people in this website by year, and whether "Protein Biosynthesis" was a major or minor topic of these publications. (umassmed.edu)
  • Below are the most recent publications written about "Protein Biosynthesis" by people in Profiles. (umassmed.edu)
  • BIN2 negatively regulated both the accumulation of BZR1 protein and chilling tolerance by suppressing ABA biosynthesis. (sciencenet.cn)
  • The biosynthesis of GAG chains is initiated by xylosylation of a serine residue of the core protein, followed by galactosylation by beta 4GalT7. (lu.se)
  • IKEN, H.H. Ecological imprinting and protein biosynthesis experiments on Drosophila melanogaster. (bvsalud.org)
  • Through unbiased genetic screening in C. elegans, we uncovered a novel role for genes necessary for ether lipid biosynthesis in the favorable effects of biguanides. (harvard.edu)
  • In order to enhance berry coloration of bright-red grape cultivars, the effects of abscisic acid (ABA) treatment on the quantity and composition of anthocyanins as well as the expression of genes related to flavonoid biosynthesis in the berry were examined. (scirp.org)
  • Quantitative real-time PCR analysis revealed that ABA treatment around véraison resulted in the upregulation of genes encoding enzymes responsible for both general flavonoid and anthocyanin biosynthesis. (scirp.org)
  • We designed codon-optimized biosynthesis pathways based on genes mined from Escherichia coli . (elifesciences.org)
  • We also investigated four oxidoreductase (OX1-4) genes in the HSAF biosynthetic gene cluster, to define the minimal gene cluster required for HSAF biosynthesis. (unl.edu)
  • Using specific primers, mRNA fragments of genes encoding sesquiterpene lactones biosynthesis enzymes were amplified and their nucleotide sequences were determined. (academicjournals.org)
  • The term' omics' refers to the fact that an entire collection of genes or metabolites is quantified and analyzed," explained Lorenzo Caputi, head of the Alkaloid Biosynthesis Project Group in the Department of Natural Product Biosynthesis at MPI and one of the lead authors. (hortidaily.com)
  • Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans. (medlineplus.gov)
  • The major splice variant of human 5-aminolevulinate synthase-2 contributes significantly to erythroid heme biosynthesis. (medlineplus.gov)
  • Our research is unravelling the genetics and biochemistry behind the biosynthesis of many types of natural products and focusing on the development of platforms for the production of compounds of pharmaceutical and industrial importance. (york.ac.uk)
  • All the aspects regarding phytostilbenes will be covered including their chemistry and biochemistry, regulation of their biosynthesis, biological activities in plants, molecular engineering of stilbene pathways in plants and microbes as well as their biotechnological production by plant cell systems. (rsc.org)
  • Variant MobA proteins were characterized for their ability to support the synthesis of active molybdenum enzymes, to bind MPT and MGD, to interact with the molybdenum cofactor biosynthesis proteins MobB and MoeA. (rcsb.org)
  • The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS. (umassmed.edu)
  • The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. (wikipedia.org)
  • In a recent study published in Nature Plants, they have identified two key enzymes, CYP87A, that catalyze the production of pregnenolone, a precursor for the biosynthesis of plant steroids. (expresshealthcaremgmt.com)
  • The PET ligand 5-hydroxy- l - 11 C-tryptophan ( 11 C-5-HTP) is the biogenic precursor for serotonin and was originally developed to assess the rate of serotonin biosynthesis by dopa decarboxylase (DDC) in the central nervous system ( 6 ). (snmjournals.org)
  • Most interestingly, the genetic feature of HSAF biosynthesis suggests that the same polyketide synthase (PKS) module acts not only iteratively, but also separately. (unl.edu)
  • Biosynthesis is usually synonymous with anabolism. (wikipedia.org)
  • Both the structure of the PGs and the GAG chains, and the expression of the enzymes involved in their biosynthesis and degradation, vary between normal cells and tumor cells. (lu.se)
  • Bioactive Compounds Biosynthesis, Characterization and Applicatio. (intechopen.com)
  • Friedhoff AJ, Schweitzer JW, Miller J. "Biosynthesis of mescaline and N-acetylmescaline by mammalian liver" Nature . (erowid.org)
  • One of the substrates for this enzyme is iso-N-acetylmethoxytyr-amine (i-NAMT), which is converted to N-acetyl-3,4-di-methoxy- I came across this 1972 abstract describing mescaline biosynthesis in mammalian liver. (erowid.org)
  • The accumulation of endogenous ABA levels in plants is a dynamic balance controlled by the processes of biosynthesis and catabolism, through the regulation of key ABA biosynthetic gene and enzyme activities. (techscience.com)
  • The increase in tissue turnover suggests an alteration in the regulation of the catecholamine biosynthesis and possibly suggests an alteration in the feedback inhibition of tyrosine hydroxylase, the key enzyme in the production of catecholamines. (medscape.com)
  • In the first chapter, we give a short review of the biosynthesis of polyketides, focusing on those which exhibit new biosynthetic features. (unl.edu)
  • The research team plans to continue studying the downstream steps of cardenolide biosynthesis and hope to solve this complex puzzle soon. (expresshealthcaremgmt.com)
  • Here, we determined that overexpression of the BR biosynthesis gene DWARF ( DWF ) or the key BR signaling gene BRASSINAZOLE \RESISTANT1 ( BZR1 ) increases ABA levels in response to chilling stress via positively regulating the expression of the ABA biosynthesis gene 9 \CIS \EPOXYCAROTENOID DIOXYGENASE1 ( NCED1 ). (sciencenet.cn)
  • This is to elucidate the specific mechanism of response and biosynthesis, signal transduction, and receptor recognition of ABA in fruit, employing comprehensive research methods, such as molecular biology, plant physiology and molecular genetics. (techscience.com)
  • This effect, in turn, results in the upregulation of SREBP-2 , which drives HMGCR nascent transcription and de novo cholesterol biosynthesis, leading to the increase of cholesterol accumulation. (nature.com)
  • In this study, we find that blocking FSH reduces serum cholesterol via inhibiting hepatic cholesterol biosynthesis. (nature.com)
  • Cholesterol Deprivation Drives DHEA Biosynthesis in Human Adrenals. (bvsalud.org)
  • This review summarizes the efficient approach for green extraction and introduces a novel strategy for microbial biosynthesis of anthocyanins, emphasizing the technological changes in production. (nih.gov)
  • CONCLUSION: Elucidation of the genetic basis of sex pheromone biosynthesis in D. saccharalis, and heterologous expression in yeast, paves the way for biotechnological production of the pheromone compounds needed for pheromone-based pest management of this species. (lu.se)
  • Led by Chenxin Li of UGA's Center for Applied Genetic Technologies in the College of Agricultural and Environmental Sciences, the research team studied the biosynthesis of two alkaloids from the Madagascar periwinkle (Catharanthus roseus) that are used as anti-cancer agents in human medicine. (hortidaily.com)
  • Here we show that the mitochondrial biogenesis regulator, PGC1α, is a pivotal determinant of renal recovery from injury by regulating nicotinamide adenine dinucleotide (NAD) biosynthesis. (nih.gov)
  • Phytochrome-interacting factor 4 (PIF4) regulates auxin biosynthesis at high temperature. (jic.ac.uk)
  • Our results demonstrate that BR signaling positively regulates chilling tolerance via ABA biosynthesis in tomato. (sciencenet.cn)
  • Major genomic deletions in independent eukaryotic lineages have led to repeated ancestral loss of biosynthesis pathways for nine of the twenty canonical amino acids. (elifesciences.org)
  • Studying the biosynthesis of arglabin and its derivatives will allow us to develop the biotechnological basis for its production, thereby increasing its availability. (academicjournals.org)
  • Previous studies have highlighted that EAA biosynthesis tends to be more energetically costly, raising the possibility that these pathways were lost from organisms with access to abundant EAAs. (elifesciences.org)
  • Whole genome sequencing across the tree of life has revealed the surprising observation that nine essential amino acid (EAA) biosynthesis pathways are missing from the metazoan lineage ( Payne and Loomis, 2006 ). (elifesciences.org)
  • In molecular biology, biosynthesis is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. (wikipedia.org)
  • beta-1,4-Gatactosyltransferase 7 (beta 4GalT7) is an essential enzyme in the biosynthesis of glycosaminoglycan (GAG) chains of proteoglycans (PGs). (lu.se)
  • The Department of Natural Product Biosynthesis at the Max Planck Institute for Chemical Ecology, led by Sarah O'Connor, is dedicated to exploring the production of pharmaceutical compounds in plants. (expresshealthcaremgmt.com)
  • It is derived from progesterone via 17α-hydroxylase and is a chemical intermediate in the biosynthesis of several other steroids, including cortisol. (cdc.gov)
  • The purpose of these studies was to detect and determine the nucleotide sequences of mRNA enzymes germacrene A synthase (GAS, EC 4.2.3.23), germacrene A oxidase (GAO, EC 1.14.14.95) and costunolide synthase (COS, EC 1.14.13.120), involved in the biosynthesis of costunolide in A. glabella . (academicjournals.org)
  • The biosynthesis can also be initiated by exogenously added beta-D-xylopyranosides with hydrophobic aglycons, which thus can act as acceptor substrates for beta 4GalT7. (lu.se)
  • In this research project we aimed to investigate the final steps of the biosynthesis of teicoplanin by a. (europa.eu)
  • The goal of the recent study was to use a new set of methods collectively termed single-cell omics to investigate specialized and rare cell types that play a central role in the biosynthesis of natural plant products and whose signals are often obscured by more abundant cell types in plant organs. (hortidaily.com)
  • The abundant other cells in the leaf dilute the high concentration when whole leaves are crushed," said Sarah O'Connor, head of the Department of Natural Product Biosynthesis at MPI. (hortidaily.com)
  • Such compounds will be valuable tools for the exploration of GAG and PG biosynthesis and a starting point for development of anti-tumor agents. (lu.se)