ValvesThrombosisImplantationSurgicalOvariesDysfunctionUnderwentAtrialHeartTranscatheterValve replacementPatientsMouse'sLeafletMortalitySevereDeviceResultImplanted bioprosthetic valveValve thrombosisMitralOvaryLeafletsAnticoagulationCardiacCarpentierReoperationTissuePatientsClinicalInsertionLong-termChildren
Valves29
- ViV TAVR is increasingly performed in the United States to treat failed bioprosthetic valves and represents 6% of all commercial TAVR cases, he noted. (medscape.com)
- The bioprosthetic heart valve is intended for surgical treatment of acquired and congenital heart diseases involving replacement of affected cardiac valves. (justia.com)
- This Gal antigen is widely expressed in other mammals and is present on an array of current animal derived biomedical devices including bioprosthetic heart valves. (ucl.ac.uk)
- These studies indicate that genetic disruption of the α-galactosyltransferase (GGTA-1) which blocks synthesis of the Gal antigen has no significant impact on the structural integrity of porcine pericardium and suggest that this tissue could be directly substituted for standard pig pericardium in biomedical devices such as bioprosthetic heart valves. (ucl.ac.uk)
- Bioprosthetic heart valves (BHV) fabricated from heterograft tissue, such as glutaraldehyde pretreated bovine pericardium (BP), are the most frequently used heart valve replacements. (nih.gov)
- Bioprosthetic valves are commonly crafted from animal tissue (heterograft/xenograft) attached to a steel or polymer guide. (bodyphysicallymentally.com)
- Background: On June 05, 2017, the U.S. Food and Drug Administration approved the Edwards Lifesciences SAPIEN S3 Valve for transcatheter mitral valve replacement of degenerated bioprosthetic mitral valves. (authorea.com)
- The simulation and experimental results show that this method can be used in the fluid-solid coupling analysis of bioprosthetic valves, and provides a reference for the further optimization of bioprosthetic heart valve. (clausiuspress.com)
- OBJECTIVE: To determine the survival of patients after transcatheter valve-in-valve implantation inside failed surgical bioprosthetic valves. (tau.ac.il)
- Novel oral anticoagulants (NOACs) are not recommended in patients with AF and mechanical valves but have not been evaluated in patients with bioprosthetic valves. (northwestern.edu)
- This study sought to evaluate the efficacy and safety of NOACs in patients with AF and bioprosthetic valves. (northwestern.edu)
- Conclusion: The use of NOAC therapy for AF in patients with bioprosthetic valves appears safe and effective in the occurrence of thromboembolic events, however, at the expense of increased bleeding. (northwestern.edu)
- Possible Subclinical Leaflet Thrombosis in Bioprosthetic Aortic Valves" by R. R. Makkar, G. Fontana et al. (hofstra.edu)
- The primary results from the RIVER Trial-Rivaroxaban for Valvular Heart disease and Atrial Fibrillation-show that rivaroxaban is comparable to warfarin for patients with bioprosthetic mitral valves. (cardiacrhythmnews.com)
- Researchers say clinicians have used direct oral anticoagulants (DOACs) such as rivaroxaban off-label for patients with bioprosthetic mitral valves who have atrial fibrillation or flutter. (cardiacrhythmnews.com)
- This is the largest trial designed to evaluate the safety and efficacy of direct oral anticoagulants in patients with bioprosthetic mitral valves and atrial fibrillation or flutter. (cardiacrhythmnews.com)
- Earlier trials of direct oral anticoagulants versus warfarin for atrial fibrillation or flutter together included fewer than 200 patients with bioprosthetic mitral valves," said lead study author Otavio Berwanger, a cardiologist and epidemiologist, and the director of the Research Institute Hcor, Heart Hospital (Hospital de Coracao) in Sao Paulo, Brazil. (cardiacrhythmnews.com)
- The results from the RIVER Trial are consistent with previous research, including ROCKET and other pivotal trials of DOACs, and can inform clinical practice for patients with bioprosthetic mitral valves," Berwanger said. (cardiacrhythmnews.com)
- The main study limitations are the open-label design, and the fact that the findings cannot be extrapolated to patients with a bioprosthetic aortic valve in the aortic position, or for patients with mitral stenosis or with mechanical valves. (cardiacrhythmnews.com)
- 3] Duncan A, Davies S, Di Mario C, Moat N. Valve-in-valve transcatheter aortic valve implantation for failing surgical aortic stentless bioprosthetic valves: A single-center experience. (bsci.org.uk)
- Younger adults requiring aortic valve replacement often receive a mechanical valve given concerns over durability of bioprosthetic valves. (bmj.com)
- Glutaraldehyde exposures among workers making bioprosthetic heart valves. (cdc.gov)
- Another 2022 meta-analysis examined the effect of DOACs versus vitamin K antagonists in treating A-fib in people with bioprosthetic heart valves. (medicalnewstoday.com)
- The influence of leaflet skin friction and stiffness on the performance of bioprosthetic aortic valves. (sun.ac.za)
- 0.001) whereas alpha-hemolytic streptococci, enterococci, and CoNS were more common on bioprosthetic valves. (lu.se)
- 5, 6 additionally, it cannot be recommended in patients with bioprosthetic valves. (acc.org)
- Bioprosthetic valves (see the image below) used in heart valve replacement generally offer functional properties (eg, hemodynamics, resistance to thrombosis) that are more similar to those of native valves. (medscape.com)
- In a retrospective cohort analysis of 4253 patients who underwent primary isolated aortic-valve replacement, 15-year survival and stroke rates were equivalent with bioprosthetic and mechanical valves. (medscape.com)
- For bioprosthetic valves, the risk of repeat surgery was greater but the incidence of major bleeding was lower. (medscape.com)
Thrombosis6
- Bioprosthetic valve thrombosis promoted by aortic root morphology? (vivitrolabs.com)
- Bioprosthetic valve thrombosis has been considered uncommon, but recent studies have shown that it is more frequent than previously thought. (vivitrolabs.com)
- The incidence of bioprosthetic valve thrombosis and related embolic complications is extremely rare, obviating the need for long-term anticoagulation. (nebraska.edu)
- As a result, experience in the diagnosis and treatment of bioprosthetic valve thrombosis is fairly limited. (nebraska.edu)
- We report the first case of antiphospholipid antibody syndrome presenting as bioprosthetic mitral valve thrombosis, 15 months after valve replacement, and successfully treated with thrombolytic therapy. (nebraska.edu)
- 1] Bioprosthetic valve thrombosis and infective endocarditis are important differential diagnoses to exclude using modalities with superior spatial resolution such as cardiac computed tomography (Figure 2B). (bsci.org.uk)
Implantation3
- Methods: A retrospective single-center cohort study was performed on all patients with bioprosthetic valve implantation, for whom a NOAC was prescribed for the indication of AF. (northwestern.edu)
- NOAC therapy began, on average, 990.0 ± 1029.1 days after bioprosthetic valve implantation for an average duration of 511.8 ± 400.8 days. (northwestern.edu)
- A subgroup analysis of 18.8% of RIVER patients with bioprosthetic mitral valve implantation within the prior three months showed a mean of 35.1 days longer without evidence of the primary outcome compared to patients treated with warfarin. (cardiacrhythmnews.com)
Surgical5
- 1. Either surgical or percutaneous therapy can be useful in symptomatic patients with discrete RV pulmonary artery conduit obstructive lesions with greater than 50% diameter narrowing or when a bioprosthetic pulmonary valve has a peak gradient by Doppler greater than 50 mm Hg or a mean gradient greater than 30 mm Hg. (wikidoc.org)
- 2. Either surgical or percutaneous therapy can be useful in asymptomatic patients when a pulmonary bioprosthetic valve has a peak Doppler gradient greater than 50 mm Hg. (wikidoc.org)
- She underwent a bioprosthetic surgical aortic valve replacement (stentless 25 mm Kohler Elan, Vascuetec) 12 years ago for calcific aortic stenosis. (bsci.org.uk)
- Surgical procedures include fistulotomy, bioprosthetic plugs, advancement flap procedures, seton techniques, and new techniques such as LIFT and FiLaC therapy. (express-press-release.net)
- There have been a relatively small number of reports pertaining to the clinical outcomes and echocardiographic findings following TAMVI or surgical redo mitral valve replacement (SRMVR) for degenerated bioprosthetic valve or failed annuloplasty rings. (frontiersin.org)
Ovaries7
- The bioprosthetic ovaries are constructed of 3-D printed scaffolds that house immature eggs, and have been successful in boosting hormone production and restoring fertility in mice, which was the ultimate goal of the research. (labmanager.com)
- This research shows these bioprosthetic ovaries have long-term, durable function," said Teresa K. Woodruff, a reproductive scientist and director of the Women's Health Research Institute at Feinberg. (labmanager.com)
- The scientists' sole objective for developing the bioprosthetic ovaries was to help restore fertility and hormone production in women who have undergone adult cancer treatments or those who survived childhood cancer and now have increased risks of infertility and hormone-based developmental issues. (labmanager.com)
- The bioprosthetic mouse ovaries were 3D printed with gelatin. (abc.net.au)
- A female mouse's ovaries were removed and replaced with 3D printed bioprosthetic ones using gelatin as the 'ink' and using eggs from different mice - enabling it to ovulate, conceive pups and give birth, the United States researchers said. (abc.net.au)
- She said it was also hoped human bioprosthetic ovaries could be used to help restore fertility to women with premature ovarian failure. (abc.net.au)
- This research shows these bioprosthetic ovaries have long-term, durable function,' she said. (abc.net.au)
Dysfunction3
- Data were collected on 156 patients with bioprosthetic TV dysfunction who underwent catheterization with planned TVIV. (ochsner.org)
- What is the aetiology of the bioprosthetic aortic valve dysfunction? (bsci.org.uk)
- We retrospectively identified patients with symptomatic mitral bioprosthetic valve dysfunction ( n = 58) and failed annuloplasty rings ( n = 14) who underwent redo SRMVR ( n = 36) or TAMVI ( n = 36). (frontiersin.org)
Underwent1
- Case presentation: At 10 years old, this female patient underwent bioprosthetic mitral valve replacement. (authorea.com)
Atrial2
- Jainandunsing JS, Bergman R, Wilkens J. Ventriculo-atrial defect after bioprosthetic aortic valve replacement. (biomedcentral.com)
- The RIVER trial followed 1,005 patients from 49 sites in Brazil who had a bioprosthetic mitral valve and atrial fibrillation or flutter for 12 months. (cardiacrhythmnews.com)
Heart11
- A method of preparing the bioprosthetic heart valve comprising the suturing of the biological transplant to the supporting and additional frame rings through the upper and lower edges of envelopes shaped like aortic sinuses. (justia.com)
- The present invention relates to the field of medicine and, more specifically, to cardiosurgery, particularly to the bioprosthetic heart valve, the methods and devices for its preparation. (justia.com)
- In this paper, according to the PISO algorithm in Fluent, the biomechanical analysis of the bioprosthetic heart valve model was carried out, and the deformation of the bioprosthetic valve was obtained. (clausiuspress.com)
- Fluid Solid Interaction Analysis of Bioprosthetic Heart Valve[J]. Chinese Journal of Medical Instrumentation,38(5),(2014), p. 325-328. (clausiuspress.com)
- The Global Bioprosthetic Heart Valve Market Report by Report Consultant is a comprehensive study about top companies, revenue share, data streams, ongoing deals, purchases and dealer volume. (industryherald24.com)
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- The report provides an analysis and overview of the future dynamics with an in-depth analysis of the most important players that are likely to contribute to the growth of the global Bioprosthetic Heart Valve market during the forecast period. (industryherald24.com)
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- Market size estimation of the Bioprosthetic Heart Valve Market on regional and global basis. (industryherald24.com)
Transcatheter2
- Bioprosthetic valve fracture (BVF) was associated with a doubling of in-hospital mortality in patients undergoing valve-in-valve transcatheter aortic valve replacement (ViV TAVR), new registry data show. (medscape.com)
- Early bioprosthetic tricuspid valve stenosis due to size mismatch in Ebstein anomaly-Successful transcatheter treatment. (bvsalud.org)
Valve replacement2
- Most of the repeat procedures involved a bioprosthetic (58.8%) or mechanical (29.4%) aortic valve replacement, while 17.6% had valve-sparing root replacement. (tctmd.com)
- However, prior studies have been underpowered to compare long-term survival implications of mechanical versus bioprosthetic valve replacement in younger adults. (bmj.com)
Patients1
- The reoperation rate was 12.1% in the bioprosthetic valve group at 15 years and 6.9% in the mechanical valve group, while major bleeding occurred in 6.6% of bioprosthesis patients and in 13.0% of the mechanical-valve group. (medscape.com)
Mouse's1
- By removing a female mouse's ovary and replacing it with a bioprosthetic ovary, the mouse was able to not only ovulate but also give birth to healthy pups. (labmanager.com)
Leaflet1
- The simulation results show that the deformation of the bioprosthetic valve mainly occurs in the free edge of each leaflet, and the deformation of the abdomen is small, and the free edge will appear curl during the valve opening. (clausiuspress.com)
Mortality1
- In propensity-matched comparisons, actuarial 15-year mortality rates were 60.6% with the bioprosthetic aortic valve and 62.1% with the mechanical valve. (medscape.com)
Severe1
- A transthoracic echocardiography showed a degenerated bioprosthetic mitral valve and severe mitral stenosis with a mean pressure gradient of 18 mm Hg. (authorea.com)
Device1
- Have you ever personally designed or built a bioprosthetic device? (indeed.com)
Result1
- In this paper, the same environment was used to simulate the pulsatile flow in the bioprosthetic valve, and the same result was obtained. (clausiuspress.com)
Implanted bioprosthetic valve1
- A factor that determines a patient's suitability is the valve size of the previously implanted bioprosthetic valve. (bmj.com)
Valve thrombosis4
- Early in the prevention and treatment of bioprosthetic valve thrombosis (BPVT), anticoagulation is effective, but the long-term outcome after BPVT is unknown. (nih.gov)
- Today we will be discussing bioprosthetic valve thrombosis (BPVT). (medscape.com)
- We describe herein the case of bioprosthetic valve thrombosis in an 82-year-old patient which resolved completely after anticoagulant therapy. (biomedcentral.com)
- also described 3 cases of bioprosthetic dysfunction resulting from valve thrombosis, at respectively 10, 4 and 2 months, all of which were treated with VKA therapy with ad integrum restitution within 2-3 months [ 17 ]. (biomedcentral.com)
Mitral2
- 12. Bioprosthetic mitral valve stenosis secondary to hypereosinophilic syndrome. (nih.gov)
- Dr. Attizzani and UH cardiac surgeon Benjamin Medalion, MD, performed a double valve procedure on an 89-year-old woman who had a failing bioprosthetic valve in the mitral position and who also needed a new aortic valve. (uhhospitals.org)
Ovary1
- NICHD-funded researchers created a bioprosthetic ovary, with oocytes (purple/blue) and follicles (green), to improve fertility in women with cancer. (nih.gov)
Leaflets1
- These bioprosthetic leaflets are distorted by mineral deposits. (imm-recherche.com)
Anticoagulation4
- 18,19 In light of this improved safety profile, controversy existed regarding the role, if any, of anticoagulation following bioprosthetic valve replacement. (acc.org)
- 20,21 Since then, various reports have reached different conclusions on the risks and benefits, optimal timing, INR goals, and adjunctive use of antiplatelets with anticoagulation after bioprosthetic AVR. (acc.org)
- Recent guidelines for antithrombotic therapy after bioprosthetic AVR have become more conservative regarding anticoagulation. (acc.org)
- In practice, actual use of anticoagulation following bioprosthetic AVR is highly variable and a recent registry study showed 38% of all patients and 49% of those at high risk were given anticoagulation. (acc.org)
Cardiac2
- The devices are a less-invasive method of inserting pacemaker leads for cardiac therapies, a novel bioprosthetic pulmonary valved conduit for congenital heart surgery, a mechanically customized physical therapy system, and a novel device to improve the outcomes of pediatric hip surgery. (newswise.com)
- Pediatric cardiac surgeons at Boston Children's Hospital are warning the medical community about a potentially fatal problem in children and young adults who received a bioprosthetic valve manufactured by Sorin. (cardiobrief.org)
Carpentier1
- Novacor - Modified Carpentier [Baxter] Edwards Bioprosthetic Supra Annula Valve, 1991, Box: 20, Folder: 1f. (nih.gov)
Reoperation2
- One of the first papers published by our group looked at patients who needed a reoperation for a bioprosthetic valve. (medscape.com)
- So, we answered those questions: among dialysis patients who are listed for a kidney transplant, what type of valve (bioprosthetic vs. mechanical) is better, in terms of mortality, reoperation and bleeding complications. (nih.gov)
Tissue1
- The basic activities of the division are to understand the blood/tissue material interactions at the interface and develop modified surfaces for various biomedical applications such as Haemoperfusion column, Bioprosthetic Heart Valve, angiogenic and wound healing materials etc. (sctimst.ac.in)
Patients1
- Bioprosthetic Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery obstruction (BASILICA) increases treatment options for high-risk patients who need heart valve procedures. (beaumont.org)
Clinical1
- [ 2 ] Initial clinical practice guidelines recommended the use of dual antiplatelet therapy for a period of 3 to 6 months post-TAVR based on extrapolations from the experience with metallic coronary stent and histopathology studies suggesting that the time frame of bioprosthetic valve neo-endothelialization occurs during this time period. (medscape.com)
Insertion1
- Another option in cases where a fistulotomy carries a high risk of incontinence is the insertion of a bioprosthetic plug. (drphanikrishnagastro.com)
Long-term1
- This research shows these bioprosthetic ovaries have long-term, durable function," Woodruff says. (nih.gov)
Children1
- Designed for infants, our bioprosthetic heart valve grows as fast as children do. (draper.com)