Biology of disease. Medical search. Frequent questions

Contributors discuss the biochemistry and cell biology of amyloid β-protein precursor (APP), tau, presenilin, β-secretase, and apolipoprotein E and their involvement in Alzheimer disease. (cshlpress.com)
The Mechanisms in Cell Biology and Disease Research Group has a specific interest in endosome-lysosome cell biology in cancer and is developing diagnostic, prognostic and imaging technology for biochemical medicine, which will benefit patients and the wider community. (edu.au)
Xenopus is remarkable for studying development and disease, including birth defects, cancer, and stem cell biology. (cshl.edu)
Cell biology of corn smut disease - Ustilago maydis as a model for biotrophic interactions. (uni-koeln.de)
Due to its highly differentiated development and the amenability for reverse-genetics U. maydis provides a model system for both fungal cell biology as well as the study of biotrophic plant interaction. (uni-koeln.de)
The present article highlights key findings in different aspects of cell biology on the corn smut disease and provides an outlook on the most intriguing open questions. (uni-koeln.de)

Researchers at the University of Pennsylvania Medical Center and other institutions have uncovered a biochemical connection between presenilin, a molecule involved in the development of Alzheimer's disease, and another protein that controls crucial aspects of developmental biology. (sciencedaily.com)
The hope is that work in Alzheimer's disease will help inform people studying aspects of developmental biology about what might be going on in their neck of the woods and vice versa," says Mark E. Fortini, Ph.D., an assistant professor of genetics and senior author on one of the papers. (sciencedaily.com)
Misprocessed APP is thought to produce the variant amyloid protein that dominates the plaques characteristic of Alzheimer's disease. (sciencedaily.com)
Two genes that code for presenilin were discovered in 1995 by investigators studying a particularly aggressive form of inherited Alzheimer's disease that strikes people as young as 30 years of age. (sciencedaily.com)
That work has demonstrated that presenilin mutations lead to the disproportionate formation from APP of a 42-amino-acid amyloid protein variant abundant in Alzheimer's disease plaques. (sciencedaily.com)
And it is here - via the shared need for presenilin in the cutting process -- that the new papers show a promising link between the fields of Alzheimer's disease neuropathology and developmental biology. (sciencedaily.com)
What we can learn from the effect of presenilin on the cleavage of Notch may be directly applicable to better understanding APP processing, leading to new insights into the causes of Alzheimer's disease," says Virginia M.-Y. Lee, PhD, a professor of pathology and laboratory medicine and codirector of Penn's Center for Neurodegenerative Disease Research. (sciencedaily.com)
The LMN, directed by Gilles Bonvento , brings together almost 60 scientists with Research interests in Neurosciences, including mechanisms of degeneration, animal models, brain imaging, and gene-, cell- and drug-based strategies for treating neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and Huntington's disease. (cea.fr)
The optogenetic activation of hippocampal astrocytes can be viewed as a novel therapeutic avenue for addressing Alzheimer's disease. (medindia.net)
In Alzheimer's disease condition, the control and adjustment of ABCA7 levels in response to inflammation and the decrease in the availability of cholesterol. (medindia.net)
Vascular dementia (VaD) is the second leading cause of dementia after Alzheimer's disease. (edu.au)
The β-amyloid (Aβ) peptide is the major constituent of amyloid plaques in Alzheimer's disease (AD) brain and is likely to play a central role in the pathogenesis of this devastating neurodegenerative disorder. (jneurosci.org)
Although the etiology of Alzheimer's disease (AD) is not completely understood, the study of disease genes that cause AD has revealed important clues about the pathogenesis of this disorder. (jneurosci.org)
Might Alzheimer's Disease Stem From a Brain Infection? (labroots.com)
The amyloid-β peptide (Aβ) is a crucial protein in the development of Alzheimer's disease (AD). (labroots.com)
It is well-established that innate immunity plays a significant role in responding to and influencing the progression of Alzheimer's disease (AD) (Heneka et al. (lu.se)

Centers for Disease Control and Prevention. (cdc.gov)
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
Centers for Disease Control and Prevention (U.S.);National Center for Chronic Disease Prevention and Health Promotion (U.S.). Office on Smoking and Health. (cdc.gov)

Irfan Rahman, PhD , has received the 2023 Society of Toxicology (SOT) Leading Edge in Basic Science Award for his contributions and advances in pulmonary toxicological sciences, specifically for his unwavering commitment to investigating how electronic cigarettes and cigarette smoke cause lung injuries and disease in humans, focusing on the fundamental alterations of DNA damage and cellular senescence. (rochester.edu)

The Neurodegenerative Diseases Laboratory (LMN) is a joint CEA and CNRS research unit (UMR9199). (cea.fr)
Our division seeks to understand how pathological aging and neurodegenerative diseases (Vascular Dementia) differ from normal aging. (edu.au)
2019). Indeed, a unique phenotype has been identified as disease-associated microglia (DAM) or neurodegenerative microglia (MGnD), which in AD is enriched with Apoe, Trem2, Lpl, Itgax, Clec7a and Lgals3 (encoding Gal-3) (Keren-Shaul et al. (lu.se)

The goal of CDC's Mycotic Diseases Branch (MDB) is to prevent illness and death from fungal diseases . (cdc.gov)
Sign up for the Fungal Diseases Newsletter for updates from CDC's Mycotic Diseases Branch. (cdc.gov)

Bioinformatics tools are software programs that are designed for extracting the meaningful information from the mass of molecular biology/biological databases and carry out sequence or structural analysis. (academicjournals.org)
The URMC Pathology PhD program trains students to answer questions about human disease using modern biomedical scientific approaches, including bioinformatics, animal and cell modelling and the study of primary human samples. (rochester.edu)
In an Advanced Online Publication in Nature Genetics Carolina Perez-Iratxeta and colleagues at the EMBL in Heidelberg describe using a bioinformatics approach to link genes to diseases (13 May 2002, DOI:10.1038/ng895). (biomedcentral.com)

New York, NY, October 14, 2021 - Today, the Huntington's Disease Society of America (HDSA) announced that five research grants totally more than $728,000 have been awarded under the Society's largest research initiative, the HDSA Huntington's Disease Human Biology Project. (hdsa.org)

Thus, supersulfide biology has opened a new era of disease control that includes potential applications to clinical diagnosis, prevention and therapeutics of diseases. (nih.gov)
Discuss the clinical manifestations and nursing management of selected disease processes and health problems. (edu.au)
yet they are crucial for understanding human biology and actualising the twenty-first century goal of personalized medicine through targeted clinical strategies for the mitigation and prevention of disease. (nature.com)
These grants represent HDSA's patient-centric research focus which brings basic and clinical researchers together to facilitate Huntington's disease (HD) science in the human condition - instead of in animal models - with the direct participation of people affected by HD. (hdsa.org)
The information comprises their clinical phenotypes, causes and type of disease. (academicjournals.org)
Human cells are key to disease research, drug discovery, and clinical translation. (businesswire.com)
In clinical trials, about 90 percent of patients who got the one-time therapy no longer needed transfusions to treat their disease. (bostonglobe.com)
Cancer systems biology therefore adopts a holistic view of cancer aimed at integrating its many biological scales, including genetics, signaling networks, epigenetics, cellular behavior, mechanical properties, histology, clinical manifestations and epidemiology. (wikipedia.org)
Cancer systems biology merges traditional basic and clinical cancer research with "exact" sciences, such as applied mathematics, engineering, and physics. (wikipedia.org)
The two diseases share many clinical features and may be clinically indistinguishable. (who.int)
11) Clinical manifestations include symptoms that are non specific and cannot be distinguished reliably from other febrile illnesses or other malarias, in addition to misdiagnosis for both malaria and dengue detections may also lead to ambiguity in term of the disease burden in this area. (who.int)
Heterozygotes usually do not manifest clinical features of the disease. (medscape.com)

Students interested in the health sciences will integrate concepts from multiple disciplines to learn how to solve global disease and health challenges using innovative approaches. (ucdavis.edu)
Understanding the complex changes that occur in the brain as the disease progresses-including the accumulation of amyloid plaques and neurofibrillary tangles-is critical for the development of successful therapeutic approaches. (cshlpress.com)
Cancer systems biology encompasses the application of systems biology approaches to cancer research, in order to study the disease as a complex adaptive system with emerging properties at multiple biological scales. (wikipedia.org)
Cancer systems biology represents the application of systems biology approaches to the analysis of how the intracellular networks of normal cells are perturbed during carcinogenesis to develop effective predictive models that can assist scientists and clinicians in the validations of new therapies and drugs. (wikipedia.org)
Cancer systems biology approaches, therefore, are based on the use of computational and mathematical methods to decipher the complexity in tumorigenesis as well as cancer heterogeneity. (wikipedia.org)
Cancer systems biology encompasses concrete applications of systems biology approaches to cancer research, notably (a) the need for better methods to distill insights from large-scale networks, (b) the importance of integrating multiple data types in constructing more realistic models, (c) challenges in translating insights about tumorigenic mechanisms into therapeutic interventions, and (d) the role of the tumor microenvironment, at the physical, cellular, and molecular levels. (wikipedia.org)
This chapter demonstrates systems biology approaches to identify candidate genes using public database. (bvsalud.org)

We propose that a suite of well-characterized hiPS cell lines with ancestral and sex diversity would become a benchmarked collection of cell lines for basic science and studies of disease mechanisms, and for the introduction of disease mutations and performance of screens for novel therapeutics. (nature.com)
This gives researchers a unique method to gain valuable insights into disease mechanisms and assess the efficacy of potential drugs for treatment. (businesswire.com)
Pathology and disease biology play a pivotal role in unraveling the underlying mechanisms and identifying potential therapeutic strategies to manage these diseases effectively [ 1 ]. (alliedacademies.org)
Pathology and disease biology play a crucial role in unraveling the underlying mechanisms of autoimmune diseases, providing insights. (alliedacademies.org)

Huntington's disease (HD) is a fatal genetic disorder that causes the progressive breakdown of nerve cells in the brain. (hdsa.org)
Since 1999, the Huntington's Disease Society of America has committed more than $20 million to fund research, with the goal of finding effective treatments to slow Huntington's disease. (hdsa.org)
Today we continue her legacy by bringing together the entire community to provide help and hope to all families affected by Huntington's disease. (hdsa.org)
The HDSA HD Human Biology Project is focused on better understanding and accelerating research on Huntington's disease in people," said Louise Vetter, President & CEO of HDSA. (hdsa.org)
Each child of a parent with HD has a 50/50 chance of inheriting the faulty gene that causes Huntington's disease. (hdsa.org)

Interestingly, the vast majority of studies exploring the gradient have focused on free-living organisms, ignoring parasitic and infectious disease (PID) species. (plos.org)

In addition to cultural, environmental and socioeconomic status, host genetic factors appear to have a role as at least 13 loci have been linked to infection or severe disease outcomes 1 . (nature.com)
The role of genetic background and ancestral relationships is seen in other complex diseases, through the presence of variants associated with certain diseases that differ among ancestries 3 . (nature.com)
As disease model cells come from an identical human genetic background to ioWild Type cells, any experimental differences observed between the wild type and the disease model can be confidently attributed to the effects caused by the disease-specific mutations. (businesswire.com)
The therapy treats the severe form of a disease called beta thalassemia, where a genetic mutation in the beta-globin gene impairs the ability of blood cells to carry oxygen throughout the body. (bostonglobe.com)
Synthetic biology is like genetic engineering on steroids. (acsh.org)
Autoimmune diseases have a strong genetic component, and certain genetic variations increase susceptibility to these conditions. (alliedacademies.org)
Pathology and disease biology have contributed to the identification of specific genetic markers associated with autoimmune diseases. (alliedacademies.org)
However, genetic predisposition alone is not sufficient for disease development, and environmental triggers play a crucial role. (alliedacademies.org)
Understanding the interplay between genetic and environmental factors is essential for a comprehensive understanding of autoimmune diseases. (alliedacademies.org)

The program uses an interdisciplinary approach to advance understanding of diseases, societal and personal impacts, and the science behind discoveries, causes, evolution, diagnosis, treatment and prevention of diseases. (ucdavis.edu)
The information should not be used for either diagnosis or treatment or both for any health related problem or disease. (medindia.net)

Finally, tool lines incorporating well-characterized disease mutations could be included in these collections, establishing a baseline against which to compare intrinsically variable patient-derived hiPS cells. (nature.com)
Scientists can now request their mutations in bit.bio's ioGlutamatergic Neurons, ioGABAergic Neurons, ioMicroglia and ioSkeletal Myocytes by contacting [email protected] . (businesswire.com)
GSD type V is an autosomal recessive disease resulting from mutations in the PYGM gene that encodes for the muscle isoform of glycogen phosphorylase (myophosphorylase). (medscape.com)

In North America, the role of ticks as vectors of two bacterial diseases, Lyme disease and Rocky Mountain spotted fever, is well documented. (purdue.edu)

About half of the 300 million people who live with a rare disease, like autoimmune disorders and cancers, do not have any treatment options. (gabio.org)
Sex differences in disease outcomes are not limited to infectious diseases - they are observed in outcomes of autoimmune diseases and cancers, and even in response to vaccination. (masslifesciences.com)
Autoimmune diseases are a group of complex disorders characterized by an abnormal immune response targeting selftissues and organs. (alliedacademies.org)
Pathology and disease biology have revealed that autoimmune diseases are primarily driven by immune dysregulation. (alliedacademies.org)
Autoimmune diseases involve the activation and dysregulation of various immune cells. (alliedacademies.org)
Autoimmune diseases often display tissue-specific pathology, reflecting the affected organs or tissues. (alliedacademies.org)
Pathology and disease biology findings have paved the way for the development of novel therapeutic strategies in autoimmune diseases. (alliedacademies.org)

The research program that Dr. Rahman has developed unites the fields of circadian biology, chromatin remodeling, inflammation, sirtuin1 deacetylase (SIRT1) dynamics, and oxidants related to the impact of tobacco products on lung toxicology. (rochester.edu)

More recently, ticks have been implicated as vectors of additional diseases in North America, including anaplasmosis , babesiosis , and ehrlichiosis . (purdue.edu)

He has been a longstanding pioneer with seminal contributions and cutting-edge research on mitophagy, steroid resistance, and lung cellular senescence and is a leader in the role of oxidative stress and redox signaling in gene transcription in tobacco-related pulmonary diseases. (rochester.edu)
The disease-relevant mutation is engineered into bit.bio's human ioWild Type cells using CRISPR/Cas9 gene editing. (businesswire.com)
The US Food and Drug Administration on Tuesday approved Bluebird Bio's gene therapy for a rare inherited blood disease. (bostonglobe.com)
Only a small fraction of the thousands of described genetically inherited diseases have been linked to a specific gene. (biomedcentral.com)
They integrated information from multiple databases to establish relationships between Medical Subject Headings (MeSH terms) related to diseases, or drugs, and Gene Ontology terms. (biomedcentral.com)
Gene ontology: tool for the unification of biology. (biomedcentral.com)
The collapsing form of FSGS has long been considered a distinct entity, but in the past few decades, we have identified more than 60 genes that are of monogenetic causes, not including disease modifiers and other gene noncoding variants that might affect progression of disease. (medscape.com)
Monitoring gene expression values in different samples using microarray technology is one of the best and most accurate ways to identify disease -causing genes . (bvsalud.org)

Guernier V, Hochberg ME, Guégan J-F (2004) Ecology Drives the Worldwide Distribution of Human Diseases. (plos.org)
Moreover, our understanding of human diseases and the existence of complete data sets provide an incomparable opportunity to explore the existence of a relationship between PID species richness and latitude, and to identify the determining factors of this latitudinal gradient. (plos.org)
With this new offering, we can cater to the vast diversity of scientific research into human diseases, providing scientists with the models they need to study their specific interests. (businesswire.com)

See Lyme Disease and 4 Emerging Tick-Borne Illnesses , a Critical Images slideshow, to help identify and treat several tick-borne conditions. (medscape.com)
You are encouraged to learn more about tick biology ( see E-243-W 'The Biology and Medical Importance of Ticks in Indiana' (PDF 757KB) ) and tick-borne diseases ( see E-244-W 'Lyme Disease' (PDF 834KB) ). (purdue.edu)

1. Suono Bio is developing a series of therapies to treat inflammatory diseases. (beckersasc.com)

To address health disparities and facilitate increasingly personalized treatments, we need to develop new models for basic and disease research that reflect diverse ancestral backgrounds and sex, and ensure that diverse populations are included among donors and research participants. (nature.com)
The RESPOND research network is investigating the underlying factors that contribute to the increased risk profile for men of African ancestry for prostate cancer 7 , and the Global Parkinson's Genetics Program is genotyping more than 150,000 people across the world to better understand the genetics of Parkinson's disease, resulting in the most ancestrally diverse Parkinson's population dataset so far 8 , 9 . (nature.com)
Anyone following the primary literature on Alzheimer s disease research knows that keeping abreast of this rapidly evolving field has become a Herculean task. (cshlpress.com)
PLOS Biology provides an Open Access platform to showcase your best research and commentary across all areas of biological science. (plos.org)
The HD Human Biology Project is a unique and important research program which continues our tradition of moving HD science forward so that effective treatments can be made available to families affected by HD as soon as possible. (hdsa.org)
iPSC-derived cells from patients offer a human model for disease research, but sourcing them with the disease-specific mutation of interest can be a complex and time-consuming process. (businesswire.com)
Our custom disease cell model offering aligns with bit.bio's mission to democratise access to human cells for research and drug discovery. (businesswire.com)
bit.bio has partnered with leading contract research organisation Charles River Laboratories to provide disease models in their early drug discovery programmes. (businesswire.com)
Pathology Ph.D. students focus on thesis research that has implications for human health and disease while working alongside senior scientists and other trainees from a wide range of disciplines. (rochester.edu)
Cancer systems biology finds its roots in a number of events and realizations in biomedical research, as well as in technological advances. (wikipedia.org)
In parallel with the exploits of molecular biology, cancer research focused on the identification of critical oncogenes or tumor suppressor genes in the etiology of cancer. (wikipedia.org)

Considering the current scenario, the theme for this year's lecture series is "Diseases, Pandemic and Vaccines" . (ncbs.res.in)
We will cover broad topics from zoonotic disease biology to vaccines and related problems and in addition the effect of such pandemics on the mind and society. (ncbs.res.in)
There currently are no vaccines against disease agents transmitted by ticks available to the public, but early antibiotic therapy is effective against the disease agents transmitted in Indiana. (purdue.edu)

These areas of the world often lack the laboratory infrastructure needed to diagnose fungal diseases, and limited availability of antifungal medications means that some patients may not have access to lifesaving treatments. (cdc.gov)

Due to a lack of standardised, easy to use and readily accessible human cell models, scientists have relied on animal models and cell lines that differ considerably from human biology. (businesswire.com)
These sessions will explore our understanding of sex differences and sex dimorphism in relation to immune responses and how presentations of infectious diseases differ based on biology. (masslifesciences.com)

Systems Biology Approach to Analyze Microarray Datasets for Identification of Disease-Causing Genes: Case Study of Oral Squamous Cell Carcinoma. (bvsalud.org)

Systems biology , an interdisciplinary approach, has emerged as a crucial analytic tool with the potential to reveal previously unidentified causes and consequences of human illness. (bvsalud.org)

Track the emergence and spread of fungal diseases by conducting molecular surveillance and genomic epidemiology. (cdc.gov)

Thus, even without delving any deeper into the complex genetics, epigenetics, or neuroendocrine biology of eating behaviours, it is not hard to understand why much of today's obesity epidemic is simply the result of our natural behaviours (biology) acting in an unnatural environment. (drsharma.ca)

At the translational level, Cancer Systems Biology should engender precision medicine application to cancer treatment. (wikipedia.org)

However, how functionality is relevant to Gal-3+ microglia and how these microglia contribute to Aβ pathology across various stages of the disease are unknown. (lu.se)

They then used the score to rank candidate genes in a given disease-associated region. (biomedcentral.com)
When this approach was tested against known disease-linked genes, the score could predict promising candidate genes. (biomedcentral.com)
Weitzman, J.B. From genes to disease. (biomedcentral.com)
The discovery of potential disease -causing genes can aid medical progress. (bvsalud.org)
Modern high-throughput methods have not solved the problem of identifying disease genes . (bvsalud.org)
One of the most recent advances in experimental molecular biology is microarrays, which allow researchers to simultaneously monitor the expression levels of thousands of genes . (bvsalud.org)
The system biology approach allows us to rapidly identify disease -causing genes and assess their viability as therapeutic targets. (bvsalud.org)
Oral squamous cell carcinoma (OSCC) is used as a model disease to show how systems biology can be used successfully to identify and prioritize disease genes . (bvsalud.org)

In my lecture, I would like to discuss the role of structural biology in the fight against pathogens taking few examples from the field. (ncbs.res.in)
Structural Biology and Taxonomy is the first volume in a series authored by leading medical mycologists. (cdc.gov)
Pathogenic Fungi-Structural Biology and Taxonomy is an important interpretation of recent literature, a valuable addition to collections, and recommended reading for investigators seeking a broad appreciation for the current state of the art. (cdc.gov)

Using cutting edge computational design, synthetic biology aims to design novel biological molecules or even entire metabolic systems. (acsh.org)
During the course of a summer, the contest asks students to design, build, and test a new biological molecule or system - using the tools of synthetic biology and their imagination. (acsh.org)
When we treat biological sex (XX versus XY chromosomes) as a variable in immunity and diseases, it can lead to a new understanding of the underpinnings of disease. (masslifesciences.com)

CDC's lead group for preventing illness and death from fungal diseases in the United States and throughout the world. (cdc.gov)
We are one of few public health groups in the world devoted to the prevention and control of fungal diseases. (cdc.gov)
We also investigate outbreaks and develop interventions to prevent fungal diseases. (cdc.gov)
Generate new information about fungal diseases and disease-causing fungi. (cdc.gov)
Respond quickly to fungal disease outbreaks and other emerging issues. (cdc.gov)
Provide training and education about fungal diseases. (cdc.gov)
Calculate the number of people who get sick from fungal diseases. (cdc.gov)
Track trends and patterns in how fungal diseases affect people. (cdc.gov)
Promote education and awareness about fungal diseases. (cdc.gov)
Develop and evaluate ways to prevent fungal diseases. (cdc.gov)
Help prepare healthcare facilities and laboratories in other countries to better detect and treat fungal diseases. (cdc.gov)
Many people at risk for and suffering from fungal diseases live in limited-resource settings. (cdc.gov)

Explain the physiological processes, interactions, and controls to maintain homeostasis in the specific areas of neurological diseases. (edu.au)
Intermittent fasting in rodents has been shown to reduce or prevent cellular dysfunction and degeneration in age-related neurological and cardiovascular diseases. (edu.au)

The most recent practice guidelines that were published by KDIGO (Kidney Disease: Improving Global Outcomes) think of FSGS in four different categories. (medscape.com)

consequently, tick-borne diseases are common. (medscape.com)
A single tick bite can transmit multiple pathogens, a phenomenon that has led to atypical presentations of some classic tick-borne diseases. (medscape.com)

In 2019, hypertensive heart disease was the main cause of 1.16 million deaths globally (Roth et al. (amrita.edu)

For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. (nih.gov)
This article reviews a new aspects of redox biology which is governed by redox-active sulfur-containing molecules-supersulfides. (nih.gov)

The overall NHANES 2005-2006 Allergy Component is designed to assess the allergen exposure, allergic sensitization, allergic symptoms and diseases, and their complex relationship in the general U.S. population. (cdc.gov)
Incidence of respiratory symptoms and chronic disease in a non-smoking population as a function of long-term cumulative exposure to ambient air pollutants (Adventist health study of smog follow-up study). (cdc.gov)

Moreover, manipulation of supersulfide levels was beneficial for pathogenesis of various diseases. (nih.gov)

Celiac disease is characterized by an inappropriate immune response to gluten, a protein found in any food containing wheat, rye, or barley. (acsh.org)

Both `malaria' and `dengue' are known to be rapidly spreading mosquito-borne diseases and of high importance in terms of both mortality and morbidity, posing a worldwide public health problem due to ease in globalised travel. (who.int)
Concurrent infections of malaria and dengue are when both the diseases occur simultaneously in an individual. (who.int)

The aim of the present study was to eluci- date the biology and prognostic role of the second ER, ERh, in patients treated with adjuvant tamoxifen. (lu.se)

It has many benefits , including improving your overall health and fitness, and reducing your risk for many chronic diseases. (medlineplus.gov)

The Cancer Genome Atlas data collection Computational algorithms to extract drivers of cancer progression from existing datasets Statistical and mechanistic modeling of signaling networks Quantitative modeling of cancer evolutionary processes Mathematical modeling of cancer cell population growth Mathematical modeling of cellular responses to therapeutic intervention Mathematical modeling of cancer metabolism The practice of Cancer Systems Biology requires close physical integration between scientists with diverse backgrounds. (wikipedia.org)

The disease model cells will support scientists in the generation of data in a human context with improved translatability in early stage drug discovery. (businesswire.com)
This offering allows scientists to commission their disease-relevant mutation of interest in bit.bio's human induced pluripotent stem cell (iPSC)-derived cells powered by opti-ox technology. (businesswire.com)
This technology may help scientists and researchers find potential treatments for rare diseases - changing treatments and hopefully, changing lives. (gabio.org)

Urban demographic expansion, deforestation and agricultural settlements in peri-urban areas, are known causes of the increase in the probability of concurrent infection of these two diseases. (who.int)

Cell therapy - where engineered cells capable of treating diseases are injected directly into a patient - is one promising approach. (gabio.org)

Because Xenopus are easy to raise, producing many thousands of eggs per day, these frogs have emerged as a premiere model for understanding of human biology from the fundamental building blocks to the whole organism. (cshl.edu)

Anatomy12

Organisms20

Diseases7

Chemicals and Drugs15

Analytical, Diagnostic and Therapeutic Techniques and Equipment44

Psychiatry and Psychology2

Phenomena and Processes77

Disciplines and Occupations42

Anthropology, Education, Sociology and Social Phenomena10

Technology, Industry, Agriculture10

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Named Groups1

Health Care14

Cell Biology6

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20231

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20211

Clinical12

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Mechanisms4

Huntington's5

Infectious disease1

Genetic9

Diagnosis2

Mutations3

Bacterial1

Autoimmune7

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Gene8

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Therapies to treat1

Research11

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20191

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