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  • Synthetic Biology
  • Our results provide insight into the molecular determinants of substrate recognition of the PnuC transporter family and demonstrate how synthetic biology can be deployed to engineer the substrate spectrum of small molecule transporters. (nih.gov)
  • signals
  • As in many other insect-insect interactions, chemical signals are known or can be assumed to play an important role for the ability of the parasite to invade the host. (lu.se)
  • Chemical signals in terrestrial vertebrates: search for design features. (semanticscholar.org)
  • We compiled a data set of the compounds that terrestrial vertebrates (amniotes) use to send chemical signals, and searched for relationships between signal compound properties and signal function. (semanticscholar.org)
  • A pioneer of a form of bioengineering known as "directed evolution," Arnold and her team of researchers at the California Institute of Technology generate new versions of P450 that do things nature never designed them to do, including mapping chemical signals in the brain and testing the toxicity of drugs. (princeton.edu)
  • Genetically altered P450s also might be useful as contrast agents for better MRI scans, providing clues about how chemical signals in the brain are connected to specific feelings or behaviors. (princeton.edu)
  • bioinformatics
  • Current Research and Scholarly Interests The Teruel Lab uses a combination of engineering and biological approaches including high-throughput screening of RNAi and DNA construct libraries, CRISPR libraries, targeted mass spectrometry, live-cell fluorescence microscopy, and bioinformatics to investigate the systems biology of cell differentiation and tissue renegeneration, with a particular focus on uncovering the molecular mechanisms underlying insulin resistance, diabetes, and obesity. (stanford.edu)
  • gene
  • This research adds a fundamental new layer of gene regulation vital for post-transcriptional gene expression, organismal development, and evolution. (nih.gov)
  • adaptation
  • Furthermore, in recent years the importance of (TEs) in evolution and adaptation to stresses has been recognized. (europa.eu)
  • The continuous evolution method allows adaptation to occur within a period of only a few days. (scripps.edu)
  • dynamics
  • Tom Atlee's research and thought innovations span from the conscious evolution of social systems to collaborative dynamics to a host of other ideas centering on group, social and political dynamics. (nottingham.ac.uk)
  • Department
  • The Department of Molecular Biology at Massachusetts General Hospital is a part of both the research community of the hospital and the Division of Medical Sciences of the Harvard Graduate School of Arts and Sciences. (massgeneral.org)
  • Lumineszenz-Resonanzenergietransfer zu Konformationsänderungen in Membranproteinen in Säugerzellen exprimiert Studieren Drew M. Dolino 1 , Swarna S. Ramaswamy 1 , Vasanthi Jayaraman 1 1 Center for Membrane Biology, Department of Biochemistry and Molecular Biology, University of Texas Health Science Center at Houston Wir beschreiben hier eine verbesserte Lumineszenz-Resonanz-Energie-Transfer (LRET) Verfahren, wo wir eine Protease-Schnittstelle zwischen dem Spender und Akzeptor-Fluorophor Stellen einzuführen. (jove.com)
  • molecules
  • Most in vitro evolution studies involve a powerful but laborious process in which a population of molecules is first challenged to perform a biochemical task, segregated on the basis of whether or not the molecules performed the task, and then amplified to produce "progeny" molecules that resemble but are not identical to their parents. (scripps.edu)
  • ecological
  • The goal is to achieve an integrated, interdisciplinary understanding of the chemical, physiological and evolutionary principles that have shaped chemical communication across insect societies of different evolutionary and ecological history. (lu.se)
  • systems
  • This will enable us to generalise about importance of chemical communication in the evolution of such systems. (lu.se)
  • They are using mRNA display in conjunction with chemical modification to select for high-affinity, modification-resistant peptides in ex vivo and in vivo systems. (mdanderson.org)
  • reaction
  • We have developed methods that allow us to carry out evolution in a continuous manner, within a single reaction mixture. (scripps.edu)
  • population
  • In a recently published article, we described the first example of "evolution on a chip," in which a population of RNA enzymes underwent 500 iterations of 10-fold exponential growth followed by 10-fold dilution, carried out during a period of 70 hours. (scripps.edu)
  • University
  • Bio Dr. Reena Thomas received her medical degree from Georgetown University School of Medicine in Washington, DC and her PhD from the City of Hope Graduate School in Duarte, California. (stanford.edu)
  • resources
  • We aim to create nanospace catalysts that can make efficient use of diverse resources, contributing to the green production of value-added chemicals. (titech.ac.jp)
  • please
  • If you do read this blog and you do something in your religious community to mark Evolution Weekend, please do tell me about it in a comment! (patheos.com)
  • system
  • Using this system in a directed evolution framework, we successfully engineer the specificity of nicotinamide riboside transporters, PnuC, to accept thiamine as a substrate. (nih.gov)
  • importance
  • Not only are crop plants of utmost importance to human sustenance, they have also experienced very rapid evolution since the time of their domestication. (liu.se)