Biology bacteriophages. Medical search. Frequent questions

citation needed] Phages were discovered to be antibacterial agents and were used in the former Soviet Republic of Georgia (pioneered there by Giorgi Eliava with help from the co-discoverer of bacteriophages, Félix d'Hérelle) during the 1920s and 1930s for treating bacterial infections. (wikipedia.org)

Meaning of Bacteriophages: Viruses parasitic on bacteria are called bacterial viruses or bacteriophages or just phages. (biologydiscussion.com)
Bacteriophages (phages), natural viruses known for infecting and killing bacteria, are the most diverse and abundant organisms on Earth. (cip.com.cn)
Within the past 100 years of research on phages, breakthroughs in genetics, molecular biology, and synthetic biology have been successfully achieved. (cip.com.cn)
Synthetic biology is driving a paradigm shift in traditional experimental research by combining "Design-Build-Test-Learn (DBTL) cycles" to rational design for phages, making synthetically designed phages promising for both top-down system optimization and bottom-up life-form reconstruction. (cip.com.cn)
A group of Scientists that includes EEB's Paul Turner along with University of California San Diego researchers has received $10M in funding support from HHMI for an initiative aiming to develop bacteriophages (phages) to fight the antibiotic resistance crisis. (yale.edu)
My research interests are in the novel approaches to infection control in medical/agriculture/industrial settings using bacteriophages aka phages. (nottingham.ac.uk)
These are called bacteriophages, or simply phages. (lu.se)
Bacteriophages, commonly known as phages, are viruses that selectively target and kill bacteria. (medscape.com)

Bacteriophages are composed of proteins that encapsulate a DNA or RNA genome, and may have structures that are either simple or elaborate. (wikipedia.org)
Therefore, there is an urgent need for implementing the motto of synthetic biology, "build to learn, build to use", and also using methods such as high-throughput sequencing and precise genome editing to create enhanced variants with unique features, improving efficacy and programmability for phage therapy. (cip.com.cn)
Characterization and Genome Sequencing of a Novel Lytic Bacteriophage Infecting Hospital-Associated Carbapenem-Resistant Klebsiella pneumoniae Strain from Dhaka, Bangladesh medRxiv. (nottingham.ac.uk)
With the genome size ranging from 271 to 275 kb, this is a novel jumbo family of bacteriophages. (frontiersin.org)
During the infection process, bacteriophages can transfer foreign DNA to their host (including virulence factors), integrate into the host genome, and/or kill their host through cell lysis ( Chen and Novick, 2009 ). (frontiersin.org)
As reviewed in 2017, jumbo bacteriophages have diverse genome sizes (ranging from 208 to 497 kb) as well as diverse virion morphology and complex virion structure ( Yuan and Gao, 2017 ). (frontiersin.org)
The DNA-packaging motor in tailed bacteriophages requires nuclease activity to ensure that the genome is packaged correctly. (rcsb.org)
The advent of large-scale genome sequencing has helped scientists identify DNA bacteriophages in the human gut, skin and blood as well as in the environment, but few researchers have looked for RNA bacteriophages in those samples (doing so requires that RNA be isolated from the samples and then converted back to DNA before sequencing). (wustl.edu)
Essential Steps in Characterizing Bacteriophages: Biology, Taxonomy, and Genome Analysis. (cdc.gov)
Genome-wide association studies (GWAS) have now identified 235 inflammatory bowel disease (IBD)-associated susceptibility loci, substantially expanding our understanding of the biology underlying these diseases. (medscape.com)

[ 2 , 3 ] We are relatively ignorant of the functional and structural contributions of microorganisms outside of gut bacteria, with only a handful of publications looking at the gut virome (viruses and bacteriophages), mycome (fungi) and other micro-eukaryotes including protozoa. (medscape.com)

It was d'Hérelle who conducted much research into bacteriophages and introduced the concept of phage therapy. (wikipedia.org)

Here we characterize eight lytic bacteriophages of E. amylovora that we isolated from the Wasatch front (Utah, United States) that are highly similar to vB_EamM_Ea35-70 which was isolated in Ontario, Canada. (frontiersin.org)

This intricate interdependency between engineering and biology is strongly evident in the single-molecule regime, where high-resolution tools are addressing previously intractable biological problems, while nanotechnology is being accelerated by advances in molecular biology. (mit.edu)
Com3 bined efforts in molecular biology, optical trapping, and molecular simulation were employed to put forth a novel mechanism for the motor's power stroke, namely that it is produced when the conserved N-terminal cover strand forms a [beta]-sheet with the neck linker to yield the cover-neck bundle. (mit.edu)
The Department of Food Science and Nutrition will host Thomas Brenner, a postdoctoral research fellow in the Wang Lab of Molecular Food Safety at the University of British Columbia, for a seminar titled "Bacteriophage-Based Biocontrol of Salmonella: A One-Health Approach" on Thursday, April 27, beginning at 12:45 p.m. (iit.edu)
Department of Molecular and Cellular Biology, University of Guelph. (uoguelph.ca)
Oct. 17 - Dr. Joseph Yankulov: Department of Molecular and Cellular Biology, University of Guelph. (uoguelph.ca)
Molecular Membrane Biology, Institute of Molecular Biology and Biophysics. (uoguelph.ca)
(POSTPONED) Nov. 7 - Dr. Mike Emes: Department of Molecular and Cellular Biology, University of Guelph. (uoguelph.ca)
Molecular biology. (jmu.edu)
2001-2004 Ph.D. (Molecular Biology). (ncl.ac.uk)
A small, easily digestible new textbook, A Genetic Switch, is destined to become an essential primer for novices in molecular biology and a rewarding recapitulation for old hands. (the-scientist.com)
2007). Bacteriophage: Genetics and Molecular Biology , 1st ed. (bionity.com)
Lots of DNA bacteriophages have been identified, but there's an incredible lack of understanding about RNA bacteriophages," explained senior author David Wang, PhD, associate professor of molecular microbiology. (wustl.edu)
His research interests include the comparative genomics and molecular biology of bacteriophages infecting lactic acid bacteria, in particular Lactococcus lactis, Streptococcus thermophilus and certain Lactobacillus species. (ucc.ie)
Vasili Hauryliuk, recipient of the Göran Gustafsson Prize in Molecular Biology 2024. (lu.se)
The prize is granted to young researchers in medicine, molecular biology, chemistry, physics and mathematics. (lu.se)
We find applications both in the biophysical/molecular biology field and in the industrial area. (lu.se)
The Molecular biology of bacterial virus systems / edited by G. Hobom and R. Rott. (who.int)

Department of Chemistry and Biology, Ryerson University. (uoguelph.ca)

An article on research conducted at WKU and a photo of a chameleon by University Photographer Clinton Lewis are featured on the cover of the November 2020 issue of the Journal of Experimental Biology . (wku.edu)

Merging the frontiers: synthetic biology for advanced bacteriophage design[J]. Synthetic Biology Journal, 2023, 4(2): 283-300. (cip.com.cn)
The World Economic Forum listed the use of bacteriophages as one of the top 10 Emerging Technologies of 2023, meaning they are highlighted it as one of the top technologies set to positively impact society within the next 3 to 5 years. (thepoultrysite.com)

This talk will discuss the recent progresses and challenges associated with developing bacteriophage-based biocontrol methods in the agri-food sector. (iit.edu)

Bacteriophages, viruses that target bacteria, were discovered in the early 20th century and gained popularity as a potential treatment for bacterial infections before antibiotics became widespread. (thepoultrysite.com)
RNA bacteriophages have been shown to infect gram-negative bacteria, which have become increasingly resistant to antibiotics and are the source of many infections in health-care settings. (wustl.edu)
His research in food and health includes the development of new antibiotics and anti-infectives, bacteriophage, human and animal pathogens, and how the gut microbiota influences health. (ucc.ie)
It is a fantastic recognition of the work that people in our lab have been doing for many years: first on protein synthesis, antibiotics targeting it and antibiotic resistance mechanisms that counter the antibiotics - and more recently, on bacterial viruses, bacteriophages. (lu.se)
Stafford and his team discovered that the feces of several endangered animals harbored bacteriophages capable of killing bacterial strains resistant to antibiotics. (medscape.com)

These bacteriophages appear to be most similar to bacteriophages that infect Pseudomonas and Ralstonia rather than Enterobacteriales bacteria by protein similarity, however, we were only able to detect infection of Erwinia and the closely related strains of Pantoea . (frontiersin.org)

A bacteriophage (/bækˈtɪərioʊfeɪdʒ/), also known informally as a phage (/ˈfeɪdʒ/), is a virus that infects and replicates within bacteria and archaea. (wikipedia.org)
A bacteriophage is a virus that infects bacteria and has a double stranded DNA core. (meritnation.com)
Enterobacteria phage λ ( lambda phage ) is a temperate bacteriophage that infects Escherichia coli . (wikidoc.org)

Structural biology of beneficial viruses: the anatomy of a flagellotropic bacteriophage and surprises in the architecture of flaviviruses. (pasteur.fr)
Studying virus entry using a multidisciplinary toolkit encompassing basic virology, computational/mathematical analysis, structural biology, and advanced microscopy. (gla.ac.uk)
Users do not have to have any previous bioinformatics or structural biology experience. (lu.se)

General and enviromental microbiology researcher and PI with independent research programme in microbial ecology, metagenomics, host-microbial interactions and bacteriophage-related technologies. (massey.ac.nz)

As such, there is a strong demand to develop eco-friendly alternative strategies to reduce the burden of microbial contamination through the application of bacteriophages. (iit.edu)
Indeed, our oceans, soils and potentially even our bodies would be overrun with bacteria were it not for bacteria-eating viruses, called bacteriophages, that keep the microbial balance of ecological niches in check. (wustl.edu)

Bacteriophages are considered natural predators of bacterial pathogens. (iit.edu)
There is indeed a pressing need to explore alternative treatments, and bacteriophages represent a promising solution with their clinically proven effectiveness against AMR bacterial pathogens. (thepoultrysite.com)

Our crystal structures of Phd-Doc from bacteriophage P1, the HigA antitoxin from Escherichia coli CFT073, and YeeU of the YeeUWV systems from E. coli K12 and Shigella flexneri confirm this inference and reveal additional, unanticipated structural relationships. (nih.gov)

Morphology of Bacteriophages 3. (biologydiscussion.com)

Systems Biology and Synthetic Biology Research Unit, Institute for Research in Immunology and Cancer. (uoguelph.ca)

This module provides an up to date understanding of how fundamental research in bacterial cell biology helps to elucidate central biological questions such as the control and regulation of cell division and of gene expression in bacteria. (ncl.ac.uk)
The lecture sequence will comprise of a module introduction followed by lectures on specific aspects of bacterial cell biology. (ncl.ac.uk)

Dr. Huskey, an associate professor in WKU's Department of Biology, is a functional morphologist and studies the feeding mechanisms and feeding habits of fish. (wku.edu)

Many large viruses, including tailed dsDNA bacteriophages and herpesviruses, assemble their capsids via formation of precursors, called procapsids or proheads. (rcsb.org)

5JBL: Structure of the bacteriophage T4 capsid assembly protease, gp21. (rcsb.org)
Structure of the bacteriophage T4 capsid assembly protease, gp21. (rcsb.org)

His current research focuses on the strategic integration of bacteriophage and peptide applications to target salmonella and E. coli along the poultry production continuum. (iit.edu)
Bacteriophage Lambda binds to the target E. coli cell, the tail tip binding to a maltose receptor. (wikidoc.org)
Shown is a micrograph image of RNA bacteriophages attached to part of the bacterium E. coli. (wustl.edu)

Q: The European Parliament has recognized bacteriophages' potential in combating antimicrobial resistance (AMR), and there is an urgent call for an appropriate regulatory framework. (thepoultrysite.com)
A: As we are facing the global threat of antimicrobial resistance, it is encouraging that the European Parliament has acknowledged the crucial role bacteriophages can play in the fight against AMR. (thepoultrysite.com)
Sublethal streptomycin concentrations and lytic bacteriophage together promote resistance evolution. (mpg.de)

Fully human monoclonal antibodies are produced using transgenic mice that contain human immunoglobulin genes or using phage display (ie, a bacteriophage-based cloning method) of immunoglobulin genes isolated from human B cells. (msdmanuals.com)

While TAs have a variety of functions, one function that has recently stepped into the limelight recently is a role in defence against bacterial viruses, bacteriophages. (lu.se)

What is your perspective on the European Union's current stance on bacteriophages as feed additives and veterinary medical products? (thepoultrysite.com)
In a striking convergence of veterinary biology and medical science, researchers from the University of Sheffield have unveiled findings that could potentially advance the treatment of diabetic foot ulcers, a condition affecting an estimated 18.6 million people worldwide. (medscape.com)

But you can think of bacteriophages and bacteria as having a predator-prey relationship. (wustl.edu)

Aging can easily be measured in C. elegans worms, a powerful laboratory model for eukaryotic biology. (marymount.edu)

Bacteriophage cultures require host cells in which the virus or phage multiply. (libretexts.org)

Department of Biology, York University. (uoguelph.ca)
Department of Cell & Systems Biology, University of Toronto. (uoguelph.ca)
Dr. Bruce Schulte, Head of WKU's Department of Biology, receives recognition for his work with African elephants by the British Broadcasting Company! (wku.edu)
For more information on elephant impacts on trees and the effects on amphibians and reptiles, contact Dr. Schulte at the Department of Biology at WKU. (wku.edu)

His work led to a manuscript recently published in the Journal of Experimental Biology which also featured cover photography by WKU's university photographer Clinton Lewis of a male veiled chameleon housed in EBS. (wku.edu)

Nature Cell Biology. (lu.se)

But the researchers also showed for the first time that these bacteriophages also may infect gram-positive bacteria, which are responsible for strep and staph infections as well as MRSA (methicillin-resistant Staphylococcus aureus ). (wustl.edu)

Wang estimates that of the more than 1,500 bacteriophages that have been identified, 99 percent of them have DNA genomes. (wustl.edu)
What we know about RNA bacteriophages in any environment is limited," Wang said. (wustl.edu)
Krishnamurthy SR, Janowski AB, Zhao G, Barouch D and Wang D. Hyperexpansion of RNA bacteriophage diversity. (wustl.edu)

Is the Subject Area "Bacteriophages" applicable to this article? (plos.org)
In this article we will discuss about Bacteriophages:- 1. (biologydiscussion.com)
The article, The role of hyoid muscles in biotremor production in Chamaeleo calyptratus , spotlights groundbreaking work on chameleon communication conducted by former WKU graduate student Samuel M. Tegge, WKU biology professor Steve Huskey, University of South Dakota biology professor Christopher V. Anderson and WKU biology professor Michael E. Smith. (wku.edu)

Anatomy5

Organisms52

Chemicals and Drugs86

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Phenomena and Processes80

Disciplines and Occupations11

Technology, Industry, Agriculture3

Information Science4

Health Care5

Treating bacterial1

Phages8

Genome10

Viruses and Bacteriophages1

Phage therapy1

Lytic bacteriophages1

Molecular17

Chemistry1

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Biocontrol1

Antibiotics5

Infection1

Infects3

Structural Biology3

Interactions1

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Escherichia1

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Mechanisms1

Capsids1

Assembly2

Coli3

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Predator-prey1

Laboratory1

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