Biological processes and accumulate. Medical search. Frequent questions

Accumulating studies have suggested that miRNAs are frequently dysregulated in tumors compared with normal tissues, resulting in aberrant expression of target genes or proteins and cancer progression 13 . (nature.com)

What is now evident is that oxygen accounts for only a small number of redox reactions in organisms and knowledge of biological redox reactions is still quite limited. (nih.gov)
Supersulfides were determined to be abundant in all organisms, but their redox biological properties have remained largely unexplored. (nih.gov)
MeHg can accumulate in aquatic organisms including fish. (alberta.ca)
Methoxychlor bioconcentrates in a number of aquatic organisms including microorganisms, snails, clams, and some fish (see Section 6.3.1), but probably does not accumulate in mammalian species due to rapid metabolism and elimination. (cdc.gov)
A trio of American scientists was awarded the Nobel Prize in physiology or medicine for revealing the mechanisms of the cellular clock that regulates biological changes in complex organisms across a 24-hour span. (latimes.com)
The research is "a great example of how studying fundamental biological processes in model organisms such as fruit flies reveals important principles that translate into a deeper understanding of human biology and disease," said Jon R. Lorsch, director of the NIH's National Institute on General Medical Sciences. (latimes.com)
Process by which unwanted microbial, plant or animal materials or organisms accumulate on man-made surfaces. (bvsalud.org)

Accumulating studies have revealed that miRNAs that participate in the myocardial fibrotic program, such as miR-18a-5p, attenuate cardiac fibrosis via regulating the Notch2 pathway [ 13 ], and miR-24-3p alleviates myocardial fibrosis through PHB2 [ 14 ]. (hindawi.com)
MicroRNAs (miRNAs) play vital roles in regulating various biological processes. (biomedcentral.com)

When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. (prosci-inc.com)
Together, the methods enhance researchers' toolkit for studying epigenetic modifications, which also include cytosine methylation and hydroxymethylation, allowing them to elucidate their potential biological role in mammalian cells. (genomeweb.com)

Cellular studies show that cadmium can accumulate in pancreatic beta cells and it inhibits the insulin secretion, impairing beta cell function. (placidway.com)
With chronic exposure, cadmium accumulates in the liver and kidneys where it is bound to metallothionein, an inducible metal binding protein. (cdc.gov)

Develop a biological knowledge base common to contemporary biologists, encompassing microscopy, cell structure, cellular membranes, and nucleic acids biology. (uaeu.ac.ae)
Use a biological knowledge base common to contemporary biologists in cellular, sub-organismic, organismic, and systems levels of biological organization. (uaeu.ac.ae)
This molecular clock mechanism ensures that specific cellular and biological processes occur at the correct time of day. (hhs.gov)

Accumulating evidence has demonstrated that supersulfides are indispensable for fundamental biological processes such as energy production, nucleic acid metabolism, protein translation and others. (nih.gov)

Present in toxic waste, they enter the body through the food chain and accumulate in both hard and soft tissues. (placidway.com)
Second, insoluble nanoparticulate carriers may accumulate in human tissues or organs. (cdc.gov)

Recent advances in neuroimaging methods have revealed that pathological proteins accumulate along specific macroscale brain networks, implicating the network architecture of the brain in the system-level pathophysiology of neurodegenerative diseases. (lu.se)
Vitamin D is a lipophilic hormone playing a key role in bone metabolism and calcium homeostasis, [ 1 ] and it is also involved in many other pathological processes [ 2 ] commonly linked with obesity. (medscape.com)

Damage can result from biological processes or from exposure to risk factors. (cancerresearchuk.org)
Despite clear, causal evidence for some exposure-disease relationships, the effects they have on the human body-the carcinogenic process itself-remain largely a mystery. (cancer.gov)
MeHg accumulates in the human body over time and because it is a known neurotoxin, it is necessary to limit human exposure to MeHg. (alberta.ca)

Accumulating evidence shows that circadian rhythm disruption worsens tissue function and injury in animals and humans consuming alcohol. (hhs.gov)
In a world that's open for business 24/7, research has shown that people who try to defy their circadian rhythms will eventually come up against the biological limits of their cells' internal clocks. (latimes.com)

All exposures we study affect our metabolism, the chemical processes that are needed to maintain life: breaking down nutrients, eliminating toxins, or building tissue. (cancer.gov)
When a woman's menstrual period came to a permanent end, toxins could accumulate and stimulate disease (in addition to a slew of physical and mental conditions). (duke.edu)

When these processes work in harmony, we produce sufficient enzymes to process the "raw material. (cancer.gov)
Ribonucleases (RNases) are RNA-processing or -degrading enzymes that hydrolyze phosphodiester bonds within RNA molecules ( 1 ). (frontiersin.org)
Copper is an integral part of many important enzymes involved in several vital biological processes. (vin.com)

Methylmercury (MeHg) is often formed from inorganic mercury during biological processes such as methylation by microorganisms in water and sediment. (alberta.ca)

Accumulating studies have revealed that RNase T2 is critical for the pathophysiology of inflammation and cancer. (frontiersin.org)
Over the past three decades, clinical and pharmacological studies have accumulated a body of evidence that not only demonstrated these therapeutic effects, but also provided significant insights into the pharmacokinetic behavior, therapeutic profile, and mode of action of scutellarin in humans and animal models. (cdc.gov)

In addition, oxygen-derived reactive oxygen species including hydrogen peroxide and nitrogen free radicals, such as superoxide, hydroxyl radical and nitric oxide radical, undergo a complicated sequence of electron transfer reactions with other biomolecules, which lead to their modified physiological functions and diverse biological and pathophysiological consequences (e.g. oxidative stress). (nih.gov)
Calcium and phosphorus are essential minerals involved in many physiological processes including metabolic pathways and mineralization of the bones. (usda.gov)
Pathologized and medicalized, this physiological transition was viewed as anything but a natural, biological process. (duke.edu)

It would take several more years for Hall and Rosbash to see that the protein encoded by that gene - called PER - went through a daily cycle of accumulating during the night and depleting over the course of the day. (latimes.com)
PPFBM represents each protein by the other molecules that associate with it in the abstracts referenced in the protein's entries in reliable biological databases. (biomedcentral.com)

In its citation for the $1.1-million prize, the Nobel Assembly at Sweden's Karolinska Institute said the researchers "were able to peek inside our biological clock and elucidate its inner workings. (latimes.com)

FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. (prosci-inc.com)

MicroRNAs have broad biological functions in cancers and may serve as ideal biomarkers. (nature.com)

Besides causing nervous system disorders, peripheral vascular disease, endocrine disruption and cancer, arsenic has also been found to alter certain biological processes that regulate insulin resistance. (placidway.com)

In the case study, researchers from Manchester Geomicro, a geo-microbiology and molecular environmental science research group affiliated with the University of Manchester, used combined chemical and microbiological contaminant degradation processes to remediate tetrachloroethene at a contaminated site in Germany. (hazmatmag.com)
Can new data sources - e.g. on-line sensor data, chemical and molecular analyses, new analytical techniques, off-gas analysis - keep up with the increasing process complexity? (bvsalud.org)

Vitamin D accumulates in adipose tissue (AT), and vitamin D deficiency is frequent in obesity. (medscape.com)
The ischemic injury underlying these illnesses is complex, involving intricate interplays among many biological functions including energy metabolism, vascular regulation, hemodynamics, oxidative stress, inflammation, platelet activation, and tissue repair that take place in a context- and time-dependent manner. (cdc.gov)
but reperfusion may introduce additional harm to the tissue through a process known as ischemia/reperfusion injury. (cdc.gov)

One facility that processes methoxychlor reports that 29 pounds were released to the air and none was released to land or water. (cdc.gov)
A facility that processes residentially collected mixed recyclables into new products available for market. (frtr.gov)

Carbo-Iron® particles accumulated the pollutants and promoted their reductive dechlorination via a combination of chemical and microbial degradation processes. (hazmatmag.com)
Despite the emergence of cis-DCE, it did not accumulate, pointing to the presence of an additional microbial degradation step. (hazmatmag.com)

This largely reflects cell DNA damage accumulating over time. (cancerresearchuk.org)

Plan and conduct biological experiments. (uaeu.ac.ae)

Passive targeting occurs due to poorly differentiated vasculature of solid tumors by a process called angiogenesis. (trialx.com)
Angiogenesis is a process involving growth of formation of new blood vessels from old pre-existing ones. (trialx.com)

Biological funneling simply means we've engineered the metabolic network of a microbes to direct the carbon from a large number of substrates to a single product," said Allison Werner, a co-author on the study. (globenewswire.com)

Biological Weapons Biological warfare is the use of microbiological agents as weapons. (msdmanuals.com)

Identify the different processes and stages that occur during animal development. (uaeu.ac.ae)
Though small customer design changes often occur, as the project develops, we strive ultimately to produce what is required for the target application or process within the pre-agreed price range. (azosensors.com)
There's been a tendency to [say] 'these rarer modifications can't possibly be important because they're present at such low levels,'" he said, but some appear to occur at relatively high levels in specific areas of the genome and might have biological functions. (genomeweb.com)

Water is also used to transport the resulting biological molecules, such as the oxygen-carrying haemoglobin in the blood, not only around the body but also to carry away the waste-products of metabolism, such as urea in urine. (xray-mag.com)

These nanoparticulate carriers themselves may be responsible for toxicity and interaction with biological macromolecules within the human body. (cdc.gov)

Due to the temperature, kinetic and biological processes accumulated in the raw cotton in Bunt, it can spread over a large surface, first in a small-local state, over time with a nonlinear law. (scirp.org)
Their immune, reproductive, digestive and central nervous systems are still developing and they spend their time closer to the ground where dust and chemicals accumulate. (who.int)

Results: The process of hormesis serves as a bridge between the biology of neuron-germ cell interactions on one hand, and the clinical relevance of these interactions on the other. (mdpi.com)
Because the proposed model is based on a biological mechanism, we believe it is an inherent part of any wastewater system and, hence, that it should be used in any WWS analysis where the aim is to relate WWS measurement to clinical cases. (bvsalud.org)

The small size of nanoparticles allows them to interact readily with biomolecules on the cell surface (receptors) and within the cell, and thus allows better understanding of complex processes that govern the behavior of cells in their normal state and during the diseased state. (trialx.com)

Consequently, the formation of carcinogenic degradation intermediate vinyl chloride was avoided due to the sequential reduction and oxidation processes. (hazmatmag.com)
To achieve its biological function, 1,25-dihydroxyvitamin D3 requires two sequential hydroxylation steps from vitamin D3 catalyzed by 25-hydroxylase and 1 α -hydroxylase. (medscape.com)

Golden, CO, Oct. 13, 2022 (GLOBE NEWSWIRE) -- Combining chemical and biological processes is a promising new strategy for the valorization of mixed plastic waste, according to researchers with the Bio-Optimized Technologies to keep Thermoplastics out of Landfills and the Environment (BOTTLE) Consortium. (globenewswire.com)

Proceedings will unfold in several stages, and as the deliberation process builds, it will add to the accumulating record of harms perpetrated by this corporation against human and non-human bodies, food, biological processes, weeds, neighborhoods, farmers, alternative forms of knowledge, and finally the environment from which all these entities emerge. (sustainablepractice.org)
The process builds upon work pioneered a decade ago: Chemical oxidation can be used to break down a variety of plastic types, which was developed by a scientist from DuPont. (globenewswire.com)

Methoxychlor in water and sediment is degraded to dechlorinated, dehydrochlorinated, and demethylated products by chemical, photochemical, and biological processes. (cdc.gov)
It is possible to create a system that changes the physical and mechanical properties of raw materials stored in cotton gins by changing their sensitivity to the external environment, through biological, thermal, chemical and other processes. (scirp.org)
We supply to a diverse range of applications in markets ranging from healthcare and pharmaceuticals, chemical process plant measurements, automotive fluid metering and hazardous measurements in petrochemical refineries, to beverage/beer dispensing. (azosensors.com)
The BOTTLE researchers developed a process that can convert mixed plastics to a single chemical product, working toward a solution that would allow recyclers to skip sorting plastic by type. (globenewswire.com)
Beckham is the senior author of a new paper published in the journal Science that details work creating a tandem chemical and biological process to produce single high-value products from waste plastic. (globenewswire.com)
The paper, " Mixed plastics waste valorization through tandem chemical oxidation and biological funneling ," was co-authored by NREL researchers and BOTTLE team members from the Massachusetts Institute of Technology, Oak Ridge National Laboratory, and the University of Wisconsin-Madison. (globenewswire.com)
The chemical catalysis process we have used is just a way of accelerating that process that occurs naturally, so instead of degrading over several hundred years, you can break down these plastics in hours or minutes," said Kevin Sullivan, a postdoctoral researcher at NREL and co-author of the paper. (globenewswire.com)
This oxidation process breaks down the PS, PET, and HDPE plastics into a complex mixture of chemical compounds-including benzoic acid, terephthalic acid, and dicarboxylic acids-that would require advanced and costly separations to yield pure products. (globenewswire.com)

As a result, gangliosides accumulate in the central nervous system until they interfere with normal biological processes. (wikipedia.org)
Spontaneous mutation and acquired immunologic processes can result in this disorder, as well. (medscape.com)

Once the new version is accepted by our customer, we install the new processes under our ISO 9001 system and generate the customer-specific part. (azosensors.com)

56 processes such as socioeconomic and environmental exposures [27-30]. (who.int)

Introduction: The primary objective of researchers in the biology of aging is to gain a comprehensive understanding of the aging process while developing practical solutions that can enhance the quality of life for older individuals. (mdpi.com)
The story of how Florence Tate, a journalist from Dayton, Ohio, and a fixture in the city's civil rights struggle, became active in African independence movements unfolds in her archive , recently processed and available for researchers at the Rubenstein Library at Duke. (duke.edu)

In 2006, Camp Pendleton's lead emissions from the bullets Marines fire while training made it the state's sixth largest producer of bioaccumulative chemicals - substances that pose a threat to human health because they accumulate up the food chain. (voiceofsandiego.org)

Mercury (Hg) enters the environment through natural processes and human activities. (alberta.ca)
Table 6-1 lists releases to the environment in 1999 from facilities that manufacture or process methoxychlor. (cdc.gov)
Waste plastics have emerged as a global energy and pollution problem as ineffectively managed materials continue to accumulate in landfills and the environment. (globenewswire.com)

In addition, in the field of nanomedicine, intravenous and subcutaneous injections of nanoparticulate carriers deliver exogenous nanoparticle s directly into the human body without passing through the normal absorption process. (cdc.gov)

the vast knowledge accumulated (1) . (who.int)

In spite of all the evidence that cigarette smoke stimulates atherogenesis and lipoprotein oxidation may play an important role [ 9 ], very little is known about the biological processes induced by smoke that contribute to increased cardiovascular disease. (biomedcentral.com)

The main biological roles of these ribonucleases are cleaving or degrading RNA substrates. (frontiersin.org)

In the industrialized world (and in many developing countries as well), poor indoor environments are often characterized by reduced ventilation, high moisture, the presence of biological agents such as moulds, and a range of chemicals present in furnishing and construction materials. (who.int)

The lack of effect of delayed feeding on the expression of some transporter genes could be related to the adequate presence of calcium and phosphorus accumulated in yolk sack that provides a minimum requirement during this short period. (usda.gov)

Dr. Derkach adds, "Metabolites can give us a window into the underlying biological processes causing disease. (cancer.gov)

I believe that formyl-C is important and it will start to feature in a number of biological contexts in work that will roll out over the next couple of years," said Shankar Balasubramanian, whose group developed redBS-Seq and published it in Nature Chemistry last week. (genomeweb.com)

To improve the ecological condition of the landscape and prevent its destruction in the process of urban development, it is essential to optimizing its ecological-sociological functions, we utilizing ecological services of the landscape as well as providing our socio-economic needs. (ac.ir)

This is a potential entry point into processing plastics that cannot be recycled at all today," said Gregg Beckham, a senior research fellow at the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) and head of BOTTLE. (globenewswire.com)
Anthrax spores are a potential biological weapon. (msdmanuals.com)

After the cotton is harvested from the fields, the high heat retention-insulation properties of the fibers in it can be explained by changes in the biological activity of the seed, heat dissipation and the state under which it is pressed into the bunt. (scirp.org)
This is thought to be due to formic acid's predilection for accumulating in high concentrations within the putamen, but the reasons for this phenomenon are unclear. (medscape.com)

It's known that, how the cotton is stored is of great importance in the initial processing of cotton. (scirp.org)

The purpose of the carbon station is for all visitors to have an experience that burning fossil fuels is the cause of the global warming that is currently taking place, and that the contribution of carbon dioxide to the atmosphere is small but significant, compared to the natural processes. (lu.se)

However, for flow meters that require a significant manufacturing process change, we do ask for a minimum order quantity to cover the additional development costs. (azosensors.com)
However, the identification of the partial dechlorination product cis-dichlorethene (cis-DCE) at depths between 12.5m and 25m below ground level one year into the study, suggested additional microbially mediated degradation processes were also involved. (hazmatmag.com)

Initiation of atherosclerotic plaque formation is a complex process. (biomedcentral.com)

The biological carbon cycle has a very fast circulation rate compared to the geological cycle. (lu.se)
Whereas the biological cycle is complete with the life span of a living organism, the geological cycle regards the formation and weathering of rocks - a very slow process - and so the circulation rate of the geological carbon cycle can take around 600 million years! (lu.se)
This means that there is much more carbon bound within the geological cycle, but also that changes in the carbon distribution can be noticed much faster in the biological cycle. (lu.se)
Or it can be transferred to the biological carbon cycle as organic material. (lu.se)
The oceans also see photosynthesis and respiration, just like the biological carbon cycle on land, which means carbon dioxide is both absorbed and emitted. (lu.se)

A major pathogenetic pathway is that accumulated copper catalyzes the formation of highly reactive oxygen species (ROS), like hydroxyl radicals. (vin.com)

Methoxychlor may react with photochemically- produced hydroxyl radicals in air, but most is probably removed from the atmosphere by wet and dry deposition processes. (cdc.gov)
G-292 (NO.CRL-1423), U2OS (NO.40342) and MNNG/HOS (NO.1547) were purchased from ATCC, and were cultured at 37 °C in DMEM medium (Biological Industries, Israel) supplemented with 10% fetal bovine serum (PAN) in a humidified incubator in an atmosphere containing 5% CO 2 . (biomedcentral.com)

Anatomy15

Organisms15

Diseases5

Chemicals and Drugs37

Analytical, Diagnostic and Therapeutic Techniques and Equipment54

Phenomena and Processes94

Disciplines and Occupations17

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture6

Information Science31

Health Care10

Suggested that miRNAs1

Organisms7

MiRNAs2

Mammalian cells2

Cadmium2

Cellular3

Fundamental biological processes1

Tissues2

Pathological2

Exposure3

Circadian2

Toxins2

Enzymes3

Methylation1

Studies2

Physiological3

Protein2

Elucidate1

Tumor1

Cancers1

Regulate1

Molecular2

Tissue3

Facility that processes2

Microbial2

Damage1

Experiments1

Angiogenesis2

Metabolic1

Microbiological1

Occur3

Metabolism1

Toxicity1

Time2

Clinical2

Cells1

Sequential2

20221

Builds2

Chemical8

Result2

Specific1

Exposures1

Researchers2

Food1

Environment3

Human body1

Knowledge1

Evidence1

Main1

Materials1

Presence1

Disease1

Work1

Functions1

Potential2

High2

Great1

Natural1

Additional2

Complex1

Cycle5

Formation1

Atmosphere2