• Manually curated GO annotations reflect our best understanding of the basic molecular function , biological process , and cellular component for this gene product. (yeastgenome.org)
  • Specific examples of recent successes include the ability to create proteins with premodified amino acids that can be expressed in prokaryotic systems where post translational modification is normally ineffective, engineering entire new multistep metabolic networks to drugs, and engineering bacteria which sense or home to specific biochemical or biological cue before releasing a therapeutic. (nih.gov)
  • Complex biochemical processes from a chemistry perspective: what are the challenges, what are the solutions used by Nature? (manchester.ac.uk)
  • Biological systems rely on intricate networks of biochemical reactions to carry out complex functions. (medium.com)
  • At the end of the course the student has knowledge of downstream and purification processes used for the industrial production of biological molecules. (unibo.it)
  • Biological processes such as cell cycle, organism development, and individual health are often controlled by a large number of molecules or biological components that interact and exchange information in a context-dependent manner. (nih.gov)
  • Over the course of these biological processes, there may exist multiple underlying "themes" that determine each molecule's function and relationship with other molecules. (nih.gov)
  • Free radicals are unstable molecules that can damage cells, including skin cells, and accelerate the aging process. (stylebeauty.info)
  • DNA computing harnesses the immense storage capacity and parallel processing capabilities of DNA molecules to perform computations. (medium.com)
  • Biological computing can facilitate the design and optimization of molecules with specific properties. (medium.com)
  • As a result, essential biological functions are progressively impaired, and organisms become increasingly vulnerable to death (i.e., ageing). (biorxiv.org)
  • All living organisms share many biological processes. (studysmarter.co.uk)
  • Biological computing, also known as biocomputing, harnesses the remarkable capabilities of living organisms and biological processes to perform complex computations and information-processing tasks. (medium.com)
  • Rule 26(5) further defines that the production of plants or animals is essentially biological if it consists entirely of natural phenomena, e.g. cross breeding or selection of organisms based on favourable characteristics. (appleyardleesgreenshoots.com)
  • Wastewater Treatment - Biological and Chemical processes is now out in a new and revised fifth edition. (polyteknisk.dk)
  • It is a basis for process understanding, design, optimization of operation and as a guide for troubleshooting for advanced wastewater operators at municipal and industrial wastewater treatment plants. (polyteknisk.dk)
  • Plant-pathogen interactions are determined by the genetic characteristics of the biological partners that participate in the interaction: a specific plant species, and a specific pathogen species or its biological variants. (frontiersin.org)
  • Exploratory analysis of multi-dimensional high-throughput datasets, such as microarray gene expression time series, may be instrumental in understanding the genetic programs underlying numerous biological processes. (biomedcentral.com)
  • NIGMS convened a workshop on November 24-25, 1997, to provide the Institute with a perspective on the emergence of new conceptual and experimental approaches to the study of complex processes such as genetic circuitry, metabolic regulation, macromolecular assembly, and other such problems at all levels of biological organization. (nih.gov)
  • Cellular automata and genetic regulatory networks are examples of cellular computing systems, where cells interact and communicate to process information and perform tasks. (medium.com)
  • Further validation of three of the identified proteins provided new insights into specific pathways and processes related to plant immunity where AtNHR2A and AtNHR2B participate. (frontiersin.org)
  • To date, studies that have estimated escalating biological noise within an ageing system have focused on variability in the expression of individual genes and/or signaling pathways( 6 - 9 ). (biorxiv.org)
  • A major bottleneck in this process is elucidating the function particularly from the large number of putative networks and pathways that arise from these efforts. (nih.gov)
  • It turned out that to a very high percentage, these key genes were significantly enriched in Gene Ontology categories or KEGG pathways that fitted very well to the biological context of cardiomyocytes differentiation. (biomedcentral.com)
  • Biological waste water treatment: activated sludge and supported biomass systems (biological filters, RBC), membrane bioreactors (MBR). (unibo.it)
  • Therefore, aerobic treatment processes take place in the presence of air and utilize those microorganisms (also called aerobes), which use molecular/free oxygen to assimilate organic impurities i.e., convert them into carbon dioxide, water, and biomass. (imemflo.com)
  • The purpose of secondary clarifiers is to separate the incoming biomass from the biological reactors into clarified effluent and thickened sludge. (ingersollrand.com)
  • Examples of other biotechnological processes: recombinant insulin production, citric acid. (unibo.it)
  • Institutions like the Fraunhofer Centre for Chemical-Biotechnological Processes (CBP) in Leuna support partners from research and industry in their efforts to transfer new technologies to an industrial scale. (biooekonomie-bw.de)
  • The CBP provides infrastructure and pilot plants that enable its partners to develop biotechnological processes that utilise renewable resources on an industrial scale. (biooekonomie-bw.de)
  • Regulation of biological processes occurs when any process is modulated in its frequency, rate or extent. (wikipedia.org)
  • Effective communication is also essential in the regulation of biological processes and function. (biorxiv.org)
  • F.W. Turek Biological rhythms play an important role in the regulation of many different physiological systems, including the reproductive system. (karger.com)
  • Before we go into the discussions of various aerobic biological treatment processes, it is important to briefly discuss the terms aerobic and anaerobic. (imemflo.com)
  • Broadly speaking, manufacturing-related R&D encompasses improvements in existing methods or processes, or wholly new processes, machines or systems. (nih.gov)
  • and (3) technologies that enable integrated and collaborative product and process development, including computer-aided and expert systems for design, tolerancing, process and materials selection, life-cycle cost estimation, rapid prototyping, and tooling. (nih.gov)
  • this is a core fundamental truth even for biological systems. (biorxiv.org)
  • High throughput biology, including genomics and transcriptomics have accelerated the discovery rate and systems biology has emerged as a method to combine multi dimensional experimental data with computational approaches to make sense of the data and generate biological or clinical hypotheses. (nih.gov)
  • Much of Dr. Chow's work involves creating and testing mathematical models that represent biological systems. (nih.gov)
  • The workshop participants ( roster below) provided examples from their own work and that of others and, in discussion, sought to define the common themes, challenges, and requirements of what was provisionally termed 'Biological Systems Analysis (BSA). (nih.gov)
  • The participants emphasized that, although there were differing views on approaches to the analysis of complexity in the context of diverse levels of organization in biological systems, a unifying goal could be identified. (nih.gov)
  • The goal is to promote the analysis of the design principles and dynamic behaviors of complex biological systems, with the expectation that such an understanding ultimately will impact the treatment of human disorders and disease. (nih.gov)
  • In September 1997, members of the National Advisory General Medical Sciences (NAGMS) Council were informed that staff intended to convene an informal workshop on analyzing complex biological systems. (nih.gov)
  • Some participants were trained in non-biological disciplines such as mathematics, physics, and engineering, with experience in the analysis of complex systems. (nih.gov)
  • In this talk, I will introduce multi-dimensional time-series models and point processes for such dynamic processes over networked biological systems. (nih.gov)
  • The course can be taken in parallel to BIOS13 Modelling Biological Systems which is also given part-time. (lu.se)
  • Waste management is the collection, transport, processing, recycling or disposal, and monitoring of waste materials, without affecting humans and other life systems and without disturbing the environment. (imemflo.com)
  • Sewage / Effluent Treatment Plant is a facility designed to receive the waste from domestic, commercial, and industrial sources and to remove materials (containing physical, chemical, and biological contaminants) that damage water quality and compromise public health and safety when discharged into water receiving systems. (imemflo.com)
  • By leveraging the inherent parallelism, adaptability, and energy efficiency of biological systems, researchers are exploring the potential of biological computing to revolutionize various fields, from healthcare and environmental monitoring to data storage and molecular design. (medium.com)
  • Biological computing involves complex biological processes and systems that are challenging to demonstrate through code. (medium.com)
  • The control information guides biological systems, from bacteria to ecosystems, in the process of natural learning executed by the universal algorithm. (philarchive.org)
  • Finally, the biosphere becomes the distributed network of communicative interactions between biological systems termed the interactome. (philarchive.org)
  • As scientific technologies advance rapidly alongside humankind's understanding our biological systems fundamental imperatives exploratory examinations towards computation intelligent modes using genomic algorithms' advances can let us predict earliest onset signs much fainter than presently possible if carefully supervised through broader community evaluation protocols. (dane101.com)
  • A current challenge in the life sciences is to understand how biological systems change their structural, biophysical and chemical properties to adjust functionality. (nature.com)
  • Principles of separation processes, choice of the appropriate unit operation for a given separation. (unibo.it)
  • By building molecular circuits and studying their behavior in cells, biologists can gain insight into biological design principles. (nih.gov)
  • To outline the basic principles of (bio)chemistry that will be relevant to an understanding of key biological structures and processes and to understand how it can be applied. (manchester.ac.uk)
  • Thus, to continue making progress, investigators may well need fundamentally new strategies, approaches, and tools to identify and understand the design principles and dynamics of complex biological processes. (nih.gov)
  • This article delves into the fascinating realm of biological computing, exploring its principles, applications, and future prospects. (medium.com)
  • By utilizing computational techniques based on biological principles, researchers can accelerate the discovery and development of new materials, drugs, and catalysts. (medium.com)
  • A new process rate is included in the model for anaerobic "hydrolysis" of XDAA to XS. (iwaponline.com)
  • Compared with using solely activated carbon method or biological method, the combined process prolongs the service life of activated carbon, improves the dewatering and anaerobic digestion of sludge, and has been used for various types of wastewater (chemical, printing, synthetic fibers, etc. (allcarbon.net)
  • The anaerobic treatment process, on the other hand takes place in the absence of air (and thus molecular/free oxygen) by those microorganisms (also called anaerobes) which do not require air (molecular/free oxygen) to assimilate organic impurities. (imemflo.com)
  • o Flexible computer-assisted integrated manufacturing equipment and intelligent processing equipment adaptable to the varied needs of biomedical research and medical care device and material production. (nih.gov)
  • To fully utilize the advances in omics technologies to achieve a more comprehensive understanding of the biological processes underlying human diseases, researchers have developed and tested MOGONET, a novel multi-omics data analysis algorithm and computational methodology. (sciencedaily.com)
  • In them, the researchers leverage biological receptors that allow detecting exogenous signals and, by means of synthetic biology , modify them to emit a response in accordance with the information they detect. (upf.edu)
  • Their massive computing power allows researchers like Dr. Chow to test many models designed to represent a biological process, each slightly different from its counterparts, until they find one that nearly matches real-world observations. (nih.gov)
  • During the past decade, biomedical researchers have been amassing an enormous volume of valuable data across a wide spectrum of the biological world. (nih.gov)
  • Recent developments in force-distance (FD) curve-based atomic force microscopy (AFM) now enable researchers to combine (sub)molecular imaging with quantitative mapping of physical, chemical and biological interactions. (nature.com)
  • Biological processes are those processes that are vital for an organism to live, and that shape its capacities for interacting with its environment. (wikipedia.org)
  • Biological processes within an organism can also work as bioindicators. (wikipedia.org)
  • the processes by which an organism has an observable effect on another organism of the same or different species. (wikipedia.org)
  • Each organism can regulate its biological processes , such as growth, nutrition, and breathing patterns. (studysmarter.co.uk)
  • Biological processes are processes that take place in a living organism that are essential and influence how an organism interacts with its surroundings. (studysmarter.co.uk)
  • In the new interpretation of natural learning the concept of biological information, guided by Peter Corning's concept of "control information", becomes the 'glue' holding the organism-environment interactions together. (philarchive.org)
  • This algorithm, summarized by the acronym IGPT (information-gain-process-translate) incorporates natural cognitive methods including sensing/perception, memory, communication, and decision-making. (philarchive.org)
  • Brain aging primarily stems from reduced neuron density that impacts several cognitive functions such as processing speed and working memory. (dane101.com)
  • Health factors like sleep patterns deficiency or heavy smoking may significantly speed up the processes of cognitive decline, while staying active by exercising physically daily in suitable activities like regular reading improves strategic planning capabilities associated with positive effects of delaying neurodegenerative conditions earlier onset symptoms. (dane101.com)
  • To recover underlying biological structure, we use existing prior knowledge regarding liver zonation to filter the spatial signal from single-cell liver data thereby enhancing the temporal circadian signal the cells are encoding. (biorxiv.org)
  • Similarly, our Cells have biological processes to help them stay alive and function properly. (studysmarter.co.uk)
  • The healthy human brain contains tens of billions of neurons, which are specialized cells that process and transmit information via electrical and chemical signals. (nih.gov)
  • Among the challenges that decoding developmental processes at single-cell resolution using single-cell RNA sequencing (scRNA-seq) poses, a unique difficulty is that scRNA-seq can only capture static snapshots of cells. (biomedcentral.com)
  • Despite the wide usefulness of these tools, they have several limitations which restrict their scope: (1) the majority of tools for pseudotime estimation require the users to explicitly designate the starting cells, meaning that they are limited to well-studied biological processes. (biomedcentral.com)
  • Figure 5: High-resolution FD-based AFM mapping of chemical and biological sites on living cells. (nature.com)
  • With MOGONET, our new AI [artificial intelligence] tool, we employ machine learning based on a neural network, to capture complex biological process relationships. (sciencedaily.com)
  • BioMOL: a computer-assisted biological modeling tool for complex chemical mixtures and biological processes at the molecular level. (nih.gov)
  • Nonhost resistance is a complex process that comprises preformed and inducible defenses, as well as the participation of hundreds of genes, many of which remain to be identified and characterized ( Senthil-Kumar and Mysore, 2013 ). (frontiersin.org)
  • For this reason, a few years ago "biological computers" began to be developed, in other words, living cellular devices that can detect multiple markers and generate complex responses. (upf.edu)
  • Thus mining the temporal expression patterns in such multi-dimensional datasets may not only provide insights into the key biological processes governing organs to grow and develop but also facilitate the understanding of the underlying complex gene regulatory circuits. (biomedcentral.com)
  • Computers are valuable tools for modeling biological processes, says the IRP's Dr. Carson Chow, and the more powerful the computer, the more complex the model can be. (nih.gov)
  • SiFT is applicable to a wide range of tasks, from the removal of unwanted variation in the data as a pre-processing step to revealing hidden biological structures. (biorxiv.org)
  • As a result, the molecular networks at each time point can undergo systematic rewiring and exhibit rich temporal structures instead of being invariant over time, as assumed in most current biological network studies. (nih.gov)
  • At the core of the aging process lies our DNA, which contains structures called telomeres. (stylebeauty.info)
  • In case of such three-dimensional datasets, at each time point the activity of all genes is measured for a number of biological replicates. (biomedcentral.com)
  • Appropriate computational methods are therefore required to analyze such high-throughput datasets specifically to identify temporal expression patterns over biological replicates and time points. (biomedcentral.com)
  • scTour's functionalities are demonstrated in a variety of biological processes from 19 datasets. (biomedcentral.com)
  • However, cellular populations encode multiple biological attributes, related to their spatial configuration, temporal trajectories, cell-cell interactions, and responses to environmental cues, which may be overshadowed by the dominant signal and thus much harder to recover. (biorxiv.org)
  • Cellular respiration is the process by which glucose is converted into ATP . (studysmarter.co.uk)
  • GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code. (yeastgenome.org)
  • Cellular computing can aid in understanding biological processes and modeling diseases, leading to advancements in precision medicine and therapeutics. (medium.com)
  • Photosynthesis is a biological process by which Plants use light energy to convert carbon dioxide and water into glucose. (studysmarter.co.uk)
  • The multiple localizations of AtNHR2A and AtNHR2B suggest that these two proteins are highly dynamic and versatile, likely participating in multiple biological processes. (frontiersin.org)
  • De novo generation of a long process of a neuron, including the terminal branched region. (zfin.org)
  • This process triggers chemical or electrical signals that either stimulate or inhibit activity in the neuron receiving the signal. (nih.gov)
  • Four main areas include: Unit process level technologies that create or improve manufacturing processes, including (1) fundamental improvements in existing manufacturing processes that deliver substantial productivity, quality, or environmental benefits, and (2) development of new manufacturing processes, including new materials, coatings, methods, and practices associated with these processes. (nih.gov)
  • The biological activated carbon process utilizes the metabolic capabilities of bacteria, fungi, algae, etc., to react with organic and inorganic compounds under suitable conditions (oxygen concentration, pH, nutrients). (allcarbon.net)
  • As part of CH2M HILL's effort to better understand the mechanisms behind these processes, a research effort was completed that was focused on developing an ASM based model which adequately reflects the performance of the Cannibal® Sludge Reduction process by Siemens. (iwaponline.com)
  • Several steps, such as transcription, RNA splicing and translation are involved in the process of gene expression, which is subject to a great many of regulatory mechanisms. (biomedcentral.com)
  • As we seek to defy the signs of aging and maintain a youthful appearance, understanding the biological mechanisms behind aging becomes crucial. (stylebeauty.info)
  • Knowledge of the main unit operations of a biotech process. (unibo.it)
  • However, estimation of biological noise for individual genes does not provide an integrative view of disorder in the aging system. (biorxiv.org)
  • EMOA- δ -TRIMAX has proven instrumental in identifying groups of genes in transcriptomic data sets that represent the functional categories constituting the biological process under study. (biomedcentral.com)
  • Microarray technology is used to measure the expression of thousands of genes over a set of biological replicates simultaneously. (biomedcentral.com)
  • Click "Gene Ontology Details" to view all GO information and evidence for this locus as well as biological processes it shares with other genes. (yeastgenome.org)
  • Since product concentration and formation rate are often very low, the resulting products need to be purified and recovered in marketable quantities in a process that is referred to as downstream processing. (biooekonomie-bw.de)
  • However, rather than test each approach himself, he leverages the IRP's considerable computing power to considerably accelerate the process of sorting the wheat from the chaff. (nih.gov)
  • I first assess the relative importance of particle-attached microbial respiration compared to other processes that degrade sinking marine particles. (whoi.edu)
  • Humans have been making use of microbial and enzymatic processes for a long time. (biooekonomie-bw.de)
  • Integrating data from various omics provides a more holistic view of biological processes underlying human diseases. (sciencedaily.com)
  • Elucidating underlying biological processes in single-cell data is an ongoing challenge and the number of methods that recapitulate dominant signals in such data has increased significantly. (biorxiv.org)
  • To approach this task, we developed SiFT (SIgnal FilTering), a method for filtering biological signals in single-cell data, thus uncovering underlying processes of interest. (biorxiv.org)
  • The physical, biological and chemical data collected are part of a long-term coastal Louisiana dataset. (noaa.gov)
  • The goal is to understand physical and biological processes that contribute to the causes of hypoxia and use the data to support environmental models for use by resource managers. (noaa.gov)
  • Thus, grouping similar biological replicates may facilitate the analysis of time series gene expression data. (biomedcentral.com)
  • I will also show how one can estimate the parameters in these models from data, and uncover and interpret the biological networks behind these biological processes. (nih.gov)
  • The latest schedule for the course Processing and Analysis of Biological Data in the schedule software TimeEdit. (lu.se)
  • Biological computing can provide efficient and secure methods for data storage, processing, and retrieval. (medium.com)
  • Biological E had presented interim safety and immunogenicity data of phase 2/3 clinical trials conducted on participants aged 5 to 18 years. (indiatimes.com)
  • Elements of reaction kinetics: reaction rate, order of reaction, catalysis, enzymes, kinetics of biological interest: Monod kinetic model, structured and segregated models. (unibo.it)
  • Product quantity can also be increased by optimising the manufacturing processes or biocatalysts used, for example by enhancing important metabolic activities, switching off less important ones (metabolic engineering) or optimising enzymes by directed evolution (enzymatic engineering). (biooekonomie-bw.de)
  • In place testing of newly installed or relocated biological safety cabinets is good practice, required in many cases. (atlantictechnologygrp.com)
  • These processes break down and convert nutrients that have been taken up into new products. (biooekonomie-bw.de)
  • The aims of the study published in December's British Journal of Psychiatry were to investigate brain function when people with psychopathy and a control group process facial emotion. (kcl.ac.uk)
  • RESEARCH OBJECTIVES The NIH, CDC, and FDA encourage research related to advanced processing in the manufacture of biomedical products and the implementation of new technologies in medical care. (nih.gov)
  • A new study from a research team led by Professor Declan Murphy has found that there are biological brain differences among criminals compared with normal people when they process facial emotion. (kcl.ac.uk)
  • The Department of Chemical and Biological Engineering at Iowa State University hosts the Biological Materials and Processes Experience for Undergraduates (BioMaP REU) summer research experience for undergraduate students. (iastate.edu)
  • The program creates novel research experiences for undergrad students from around the country in the areas of biological materials and processes. (iastate.edu)
  • For IRP senior investigator Carson Chow, Ph.D. , this process of testing and throwing out one potential solution after another is an essential part of his research, so much so that he may go through thousands of iterations before arriving at one that works. (nih.gov)
  • Membrane separation processes: classification based on the driving force, description and use of different membrane processes in biotechnology. (unibo.it)
  • Applied for pre-processing, SiFT outperforms state-of-the-art methods for the removal of nuisance signals and cell cycle effects. (biorxiv.org)
  • We are investigating how social signals like faces and eye gaze are processed in autism, including exploration of the brain signals that underlie these processes, as well as how well autistic people understand other peoples' minds. (cardiff.ac.uk)
  • Spanish researches have conducted a cross-sectional study with 886 participants, where they have compared their total energy intake and telomeres length (a universal marker of biological age). (gowinglife.com)
  • We will also discuss how these processes are related to the carbon cycle. (studysmarter.co.uk)
  • The biological activated carbon (BAC) process mainly utilizes the pore structure and surface area of activated carbon to achieve high efficiency as for growing concern of the treatment of water containing more and more kinds of pollutants nowadays. (allcarbon.net)
  • The process uses activated carbon as a carrier, and forms a biofilm on the surface of the carbon. (allcarbon.net)
  • Combining ozone and biological activated carbon is one of the mostly-used techniques in water plants. (allcarbon.net)
  • Biological activated carbon fluidized bed has high efficiency in removing various kinds of pollutants. (allcarbon.net)
  • p>This section provides any useful information about the protein, mostly biological knowledge. (uniprot.org)
  • Biological E has developed the protein subunit Covid vaccine Corbevax. (indiatimes.com)
  • Adult brains may even generate new neurons, a process called neurogenesis. (nih.gov)
  • Use of process simulators to size apparatuses and bioprocess design. (unibo.it)
  • Aerobic respiration is typically invoked as the dominant mass-balance sink for organic matter in the upper ocean, yet many other biological and abiotic processes can degrade particulate and dissolved substrates on globally significant scales. (whoi.edu)