• Tumor markers. (powells.com)
  • Tumor markers -- Diagnostic use -- Congresses. (powells.com)
  • This study examined, in a randomized double-blind placebo-controlled clinical trial, the effects of dietary flaxseed on tumor biological markers and urinary lignan excretion in postmenopausal patients with newly diagnosed breast cancer. (aacrjournals.org)
  • The selection of patients for tumor-specific therapies using molecular/biological properties of the patient's tumor has been a long tradition in breast cancer (e.g., estrogen receptor, progesterone receptor, and HER-2/ neu ) but has not been widely accepted in lung cancer therapy selection ( 1 , 2 ). (aacrjournals.org)
  • Determination of tumor markers has not been very successful due to the low sensitivity and specificity of the techniques used and the requirement of large volumes of biological samples or the use of invasive methods for collecting them. (urosario.edu.co)
  • The serum tumor markers arise, as a useful tool to obtain information about the disease progress and constitute as a scientific challenge to improve its applicability in early diagnosis, prognosis, monitoring of the disease and evaluation of therapeutic efficacy. (urosario.edu.co)
  • The objective of this study was to evaluate clinical and microscopic features of squamous cell carcinomas using immunohistochemical analysis and assessing biological markers of angiogenesis and tumor vascular activity (anti-CD31, anti-CD34, Factor VIII), cell proliferation (Ki-67), and loss of cell suppression (p53). (bvsalud.org)
  • Our findings suggest an important contribution of tumor markers in the diagnosis and prognosis of these malignancies, as well as in treatment planning. (bvsalud.org)
  • Inflammatory markers, such as interleukin-6 (IL-6), have been associated with both the malignant transformation of epithelial cells and tumor progression, thus linking low-grade inflammation with a higher risk of cancer and recurrence in the survival phase. (jmir.org)
  • The potential use as a tumor marker was suggested by Gronowitz et al. (wikipedia.org)
  • The enzyme suggested as a tumor marker in malignant disease is the cytosolic cell cycle dependent TK1 that is present during cell division in quantities much larger than TK2 and is therefore set free to the circulation in quantities that completely dominate the activity of thymidine kinase in blood and other body fluids. (wikipedia.org)
  • Scientists at the Salk Institute for Biological Studies may have found one explanation for the puzzling variety in brain organization and function: mobile elements, pieces of DNA that can jump from one place in the genome to another, randomly changing the genetic information in single brain cells. (salk.edu)
  • The Salk Institute for Biological Studies in La Jolla, California, is an independent nonprofit organization dedicated to fundamental discoveries in the life sciences, the improvement of human health and the training of future generations of researchers. (salk.edu)
  • Stephen Wood summarises a systematic review of biological markers for treatment response in first episode psychosis, which discusses a number of hot topics in this field including inflammation, infectious disease and oxidative stress. (nationalelfservice.net)
  • Cohen, the Robert E. Doherty Professor of Psychology in CMU's Dietrich College of Humanities and Social Sciences, suggests that "telomere length is a relatively consistent marker across the life span and that it can start predicting disease susceptibility in young adulthood. (redorbit.com)
  • In conclusion, the results of this thesis indicate that blood telomere length has potential to act as an independent prognostic marker in malignancy. (diva-portal.org)
  • In a separate group of five blood donors, a remarkable drop in telomere length was detected in one donor over a 6--?month period, whereas the other donors exhibited only small fluctuations in telomere length.In conclusion, the results of this thesis indicate that blood telomere length has potential to act as an independent prognostic marker in malignancy. (avhandlingar.se)
  • Now, researchers may be able to predict which people will become infected by viruses based on certain biological markers found in their chromosomes . (redorbit.com)
  • The researchers, led by Carnegie Mellon´s Sheldon Cohen, found that these biological markers in the immune system can predict our ability to fight off infections such as the common cold . (redorbit.com)
  • Athens, Ga. - A team of researchers led by faculty at the University of Georgia has identified a number of biological markers that make it possible to classify mental disorders with greater precision. (eurekalert.org)
  • In addition to finding more accurate ways of categorizing disease types, the researchers hope that this project may inspire a renewed interest in psychiatric drug development, which has been stymied recently by a lack of clear biological targets. (eurekalert.org)
  • But now, researchers from Northwestern University in Evanston, Ill., have found a biological marker that could indicate when a person is struggling with reading comprehension. (foxnews.com)
  • Researchers have confirmed the role played by three particular molecules known as cytokines in causing Type 2 diabetes and have identified these molecules as early biological markers that may be used to more accurately predict future diabetes in healthy individuals. (emaxhealth.com)
  • BigDataViewer gradually is researchers with sustainable download biological markers of so, while the woman you are to be enables just only new. (max-access.com)
  • At that time , they and several other researchers noted that there were significant limitations in our understanding of the complex interactions that occur among biological , psychological , and social factors across the life span . (uakron.edu)
  • In news that is bound to pave the way for a greater understanding of dyslexia, Northwestern University researchers report they have found a biological mechanism that appears to play an important role in the reading process reports, the Science Daily. (org.in)
  • Peter Smart, download biological of UX and relation staging at Fantasy, is that systems will Search more rubbish but represents we Even work a certain cell to succeed. (max-access.com)
  • WHO HQ Library catalog › Results of search for 'su:{Biological markers. (who.int)
  • Jumping genes with ORF0 are basically protein factories with wheels, and over the eons evolution has been driving the bus. (salk.edu)
  • One of these biological markers is C-reactive protein (CRP).Aim. (deepdyve.com)
  • 00:03:31.24 And because I was working on a transparent animal, 00:03:37.00 Caenorhabditis elegans, I was looking at gene expression, 00:03:41.20 I suddenly realized that this protein, GFP, 00:03:45.10 would make a terrific marker for our experiments. (ibiology.org)
  • For protein-based markers, ferritin/transferrin and vitamin D-binding protein levels have been suggested for isocyanate-OA. (cdc.gov)
  • Measurements included were biological salivary markers (IL-6 and C-reactive protein [CRP]), self-completed questionnaires (the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, the user version of the Mobile Application Rating Scale [uMARS] and an ad hoc clinical and sociodemographic questionnaire) and physical objective measures (accelerometry, weight and height). (jmir.org)
  • For this, we propose to measure blood and urinary markers of formation and bone resorption before consumption, then 45 and 90 days after daily consumption of 10 g of hydrolyzed collagen. (clinicaltrials.gov)
  • We have reviewed primary research in this area, noting that factors involved in the susceptibility and expression of PTSD symptoms are more complex and heterogeneous than is commonly stated, with extensive findings which are inconsistent with the stereotypic behavioral and biological profile of the PTSD patient. (nih.gov)
  • Markers of biological age have recently proven to be strong mortality predictors independent of other risk factors. (aldringoghelse.no)
  • Taken together, these studies identify some of the factors contributing to biological aging and ultimately help to select the ideal targets for future preventive measures. (aldringoghelse.no)
  • Discussion: This study aims at collecting precise clinical data, comprehensive geriatric assessment, risk factors, and biological data from acute care patients. (lu.se)
  • But if we can identify a biological mechanism that contributes to disease, then we may reinvigorate drug development, and that's what we're trying to provide. (eurekalert.org)
  • We have been trying to find a biological marker for Parkinson's for many years and the reason is that we need a tool to measure change in the disease in clinical trials in a very sensitive way. (medicalsearch.com.au)
  • Here we review 23 articles on the HD prodrome, all of which related cognition to a biological marker of disease burden (i.e., genetic load, neuroimaging). (ed.gov)
  • These findings indicate that cognitive signs can be reliably detected in the HD prodrome when comparing cognition to additional disease markers, however, there continues to be significant variability on cognitive findings among large and methodologically rigorous studies. (ed.gov)
  • On the other hand, the reshuffling of an existing ORF0 sequence during a jump could result in a disease-causing mutation. (salk.edu)
  • We also evaluated the correlation between ccfDNA and the clinical activities or the response for biological DMARDs, using disease activity score of 28 joints erythrocyte sedimentation rate (DAS28ESR) and the european league against rheumatism (EULAR) response criteria. (bmj.com)
  • Before viewing these same ideas, it is soon few to help Fast that tablets do how to extract download biological markers of alzheimers disease from the set when they have it. (max-access.com)
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  • An understanding of biological variation of markers is essential to interpretation of changes in response to disease events. (aaccjnls.org)
  • Data on biological variation should be generated early in the evolution of new diagnostic and disease monitoring tests ( 19 ). (aaccjnls.org)
  • Their current aim is to look for early biological markers of autism through the use of various behavioral observations and neuropsychological studies conducted at the Birkbeck Babylab (University of Birkbeck, London). (autismparentingmagazine.com)
  • The research team recruited more than 700 patients with psychosis and some of their first-degree relatives--a parent, sibling or child--as well as a control group of healthy individuals to see if they could identify brain-based diagnostic markers to differentiate these conditions. (eurekalert.org)
  • Czerwionka M, Korf H-W, Hoffmann O, Busch H, Schachenmayr W (1989) Differentiation in medulloblastomas: correlation between the immunocytochemical demonstration of photoreceptor markers (S-antigen, rod-opsin) and the survival rate in 66 patients. (springer.com)
  • Methods The study group included 29 patients with RA who started biological DMARDs therapy. (bmj.com)
  • Eight markers were evaluated in plasma EVs from CRC patients and healthy controls. (biomedcentral.com)
  • Prospective validation of a risk score based on biological markers for predicting progression free survival in Binet stage A chronic lymphocytic leukemia patients: results of the multicenter O-CLL1-GISL study. (semanticscholar.org)
  • A risk score based on three biological features (CD38, ZAP-70, and IGHV mutational status) was previously developed to predict progression-free survival (PFS) in untreated Binet A CLL patients. (semanticscholar.org)
  • Biological markers (CD38, ZAP-70, and IGHV mutational status) and gene expression profiles (GEP) of leukemic cells from CLL patients included in a prospective multicenter observational study (O-CLL1-GISL protocol, clinicaltrial.gov ID:NCT00917549) were used to assess the value and reproducibility of this score. (semanticscholar.org)
  • To date, 468 Binet A patients were classified as low- (0 positive marker), intermediate- (1 positive marker), or high-risk (2 or 3 positive markers) using the progression risk score. (semanticscholar.org)
  • In the biological markers trials, biofluid samples (i.e., cerebrospinal fluid 'CSF' and plasma) were obtained from 11 patients with PD. (otago.ac.nz)
  • Data from ongoing studies are considered essential to improve assessment of existing markers and to identify those for early follow-up of treated patients. (gob.ar)
  • Different therapeutic strategies have shown efficacy in the modification of these and other biological parameters, but with contradictory results. (jmir.org)
  • An optical-mechanical sensor of our own design fixed the clicker trigger moment to have synchronized the biomechanical and electrophysiological parameters of the shooting process - and thereby identify and track by the relevant dominant markers the shooting process phases. (teoriya.ru)
  • VEGF and CD133 mRNAs comprise a unique CRC signature in EVs that has the potential to act as a novel, non-invasive, and accurate biomarker that would improve the current diagnostic platform for CRC, while also serving to strengthen the value of EV mRNA as diagnostic markers for myriad of diseases. (biomedcentral.com)
  • BioMARK (Biological Marker of Auditory Processing) is a neurophysiological test used to quickly and objectively identify disordered processing of sound - the auditory brainstem response (ABR) to speech - which has been associated with learning impairments in many children. (listenandlearn.com.au)
  • Transposable L1 elements, or "jumping genes" as they are often called, make up 17 percent of our genomic DNA but very little is known about them. (salk.edu)
  • This diversity arises from a new component of itinerant sections of genetic code known as jumping genes. (salk.edu)
  • In a paper published October 22, 2015 in Cell , Salk scientists report finding human and chimp DNA peppered with sequences of genetic code they've dubbed ORF0, which spreads throughout the genome on jumping genes. (salk.edu)
  • This discovery shows that jumping genes are an even more important source of variation in the primate genome than we thought, whether you're looking at the level of different species, different people or even the different cells within an individual's body," says Rusty Gage , senior author of the paper and a professor in Salk's Laboratory of Genetics . (salk.edu)
  • With the sequencing of the human genome, it became clear that jumping genes-mobile genetic elements first discovered in maize by Barbara McClintock in the early 1950s-were also present and highly active during human evolution. (salk.edu)
  • The evolutionary importance of jumping genes was highlighted by the results of another recent study by Gage and collaborators at Stanford. (salk.edu)
  • The findings, also reported in Cell, suggested that jumping genes played a role in the evolutionary split between humans and other primates. (salk.edu)
  • In the more recent study that uncovered ORF0, Gage and his colleagues focused on a class of jumping genes known as LINE-1 elements, which make up about 17 percent of the human genome. (salk.edu)
  • These elements contain all the necessary genetic machinery for moving themselves and other classes of jumping genes, unaided, to elsewhere in the genome. (salk.edu)
  • Here, a self-specialization mechanism is identified as a possible biological role of jumping genes, in particular LINE-1 retrotransposition. (rsc.org)
  • The mechanism involves competition within a gene set in which a subset of genes cooperating in particular biological processes. (rsc.org)
  • This reshapes the cell genome toward self-specializing of those biological processes that are carried out with a high number of LINE-1 containing genes. (rsc.org)
  • If enough of these jumps occur, they could allow individual brains to develop in distinctly different ways. (salk.edu)
  • According to lead author of the study Nina Kraus, Hugh Knowles Professor of Neurobiology, Physiology and Communication at Northwestern, the biological underpinnings all revolve around the brain and a seemingly unrelated action - a person's hearing ability. (foxnews.com)
  • In recent years, the biological effects and mechanisms of action of estrogen have been deeply revisited, and extensive efforts have been made to better understand both the physiology and pathophysiology of estrogen actions in different target tissues. (springer.com)
  • The biomarker is objectively measured and evaluated as an indicator of normal biological processes or pharmacological responses to therapeutic interventions. (deepdyve.com)
  • Despite recent progress in the development of potentially improved drugs, there is no consensus among different research groups on the lack of therapeutic response markers to evaluate efficacy of newly proposed drugs early after treatment. (gob.ar)
  • Despite their value in guiding modeling efforts, there are few data documenting large-scale patterns of invasion for species that spread primarily via jump-dispersal or that spread by multiple processes. (pnas.org)
  • Although clearly adaptive, the way in which specialization of cells is realized remains incompletely understood as it requires the reshaping of a cell's genome to favor particular biological processes in the competition on a cell's functional capacity. (rsc.org)
  • The selection of a particular biomarker of SHSe and the analytic biological medium depends on the scientific or public health question of interest, study design and setting, subjects, and funding. (pubmedcentralcanada.ca)
  • Our findings add some evidence of a biological embodiment in response to stress which ultimately affects mortality. (springer.com)
  • Extensive research has identified stereotypic behavioral and biological abnormalities in post-traumatic stress disorder (PTSD), such as heightened autonomic activity, an exaggerated startle response, reduced basal cortisol levels and cognitive impairments. (nih.gov)
  • In: Hensley K., Floyd R.A. (eds) Methods in Biological Oxidative Stress. (springer.com)
  • The report, Using Biological Markers to Measure Stress in Listeners of Commercial Talk Radio , established that a methodology employing biological markers can help determine the physiological and psychological effects of hate speech. (ucla.edu)
  • This manuscript reviews recent evidence supporting the utility of telomeres and mitochondrial DNA copy number (mtDNAcn) in detecting the biological impacts of adverse childhood experiences (ACEs) and outlines mechanisms that may mediate the connection between early stress and poor physical and mental health. (acesconnection.com)
  • and culturable fungi and bacteria, endotoxin, markers of fungi (extra-cellular polysaccharides specific for Penicillium/Aspergillus, ergosterol, and beta(1-->3) glucans) and cat allergen in chair and floor dusts. (cdc.gov)
  • Specifically, we interrogate the hypothesis of a cumulative biological risk (allostatic load) reflecting 4 physiological systems potentially predicting future risk of death (N = 132). (springer.com)
  • Employing a computational functional genomics approach, we demonstrate the biological plausibility in functional genomic datasets of potentially chronifying situations and interpret our results in relation to a biological mechanism of self-specialization of complex systems in response to a persistent challenge as met in chronifying traits. (rsc.org)
  • There are apparently no strategies in which telemedicine, and specifically mobile health (mHealth), are used as a means to potentially cause biological changes. (jmir.org)
  • The ability to modify/visualize biological surfaces, and then study the modified cell/virion in a range of in vitro and in vivo environments is essential to gaining further insight into the function of specific molecules or the entire entity. (jove.com)
  • But while this technology is being refined and improved, medical experts are still searching for biological markers that can detect brain injuries in athletes now, and recent findings suggest they may exist in the blood. (consumeraffairs.com)
  • Study of Change in Biological Markers of Bone Metabolism Following Consumption of Hydrolyzed Collagen for 3 Months in Healthy, Non-osteoporotic, Menopausal Women. (clinicaltrials.gov)
  • Biogerontology is the study of the aging of biological systems. (isharonline.org)
  • This study examines the expression of intestinal differentiation markers in this type of breast carcinoma. (biomedcentral.com)
  • But preliminary research from a new Stanford study offers further evidence that it is a physical ailment with biological causes and not a psychological condition - and suggests an approach that may help detect it. (mercurynews.com)
  • Self-termination of the mechanism is achieved by allowing LINE-1 to also occasionally jump into the coding region of itself, thus destroying the information about competitor destruction by successively decreasing the number of LINE-1 until the mechanism ceases. (rsc.org)
  • Nonnuclear markers may be recombination insensitive, and mtDNA has been used to demonstrate a single hereditary line, where the mtDNA was inherited unilinearly (Whittaker et al. (barnardhealth.us)
  • Identification of acute kidney injury (AKI) is predominantly based on changes in plasma creatinine concentration, an insensitive marker. (aaccjnls.org)
  • Harris HA, Katzenellenbogen JA, Katzenellenbogen BS (2002) Characterization of the biological roles of estrogen receptors, ERα and ERβ, in estrogen target tissues in vivo through the use of an ERα-selective ligand. (springer.com)
  • Six specialized download biological markers of alzheimers writers are reusable tissues and best 1990s for learning subsequent way overlays. (max-access.com)
  • Now knowing the biological underpinnings of dyslexia and reading impairment, Kraus hopes this technology can one day be used by teachers and scientists to better understand how the reading process develops in a child's brain - and to ultimately help them become better readers if they start to fall behind. (foxnews.com)
  • Estrogen is a pivotal factor in the regulation of a wide array of biological systems, in both the male and the female, which include not only the reproductive axis but also bone, the cardiovascular system, adipose tissue and the brain. (springer.com)
  • Apart from their activity in testis and ovaries, jumping L1 elements are not only unique to the adult brain but appear to happen also during early stages of the development of nerve cells. (salk.edu)
  • The frequency and distances of jump-dispersal events are thought to be stochastic, difficult to determine, and therefore have rarely been quantified (refs. (pnas.org)
  • Results showed the potential for such data to provide the basis for a standardized approach to the measurement of cleaning effectiveness, based on detection and quantification of pollutant loads of biological origin, across critical surfaces in school building environments. (ciriscience.org)