• Connecting the clinical state of age-related frailty with underlying biological age, as measured by biomarkers, has long been an elusive goal. (biomedcentral.com)
  • Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry. (ox.ac.uk)
  • Contexts of use and how to approach candidate biomarkers in biological specimens other than cerebrospinal fluid (CSF), e.g. blood, were precisely defined. (ox.ac.uk)
  • World Journal of Biological Psychiatry, 18(5):330-356. (uzh.ch)
  • An objectively measured variable or trait that is used as an indicator of a normal biological process, a disease state, or effect of a treatment. (syenza.com)
  • A biological marker or biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. (sbir.gov)
  • Results: Outcomes include objectively measured physical activity, biological markers of health, and self-report survey data at baseline, after the 6-month intervention or control period, and at a 12-month follow-up. (cdc.gov)
  • Diagnostic markers are key in clinical trials to differentiate FTD from other neurodegenerative dementias. (unimi.it)
  • The objective of this study was to evaluate clinical and microscopic features of squamous cell carcinomas using immunohistochemical analysis and assessing biological markers of angiogenesis and tumor vascular activity (anti-CD31, anti-CD34, Factor VIII), cell proliferation (Ki-67), and loss of cell suppression (p53). (bvsalud.org)
  • Since the renal function is assessed in clinical routine, also markers of the renal function have gained increasing interest. (degruyter.com)
  • The ability to distinguish between biological sex and sociocultural gender would revolutionize health research and clinical practice by allowing us to move beyond a binary view of gender completely confounded by sex. (bristol.ac.uk)
  • Of these, three displayed particularly aggressive biological behavior, whereas there were no clinical details provided for the others. (ox.ac.uk)
  • We investigated bax/bcl-2 ratio by flow cytometry in 502 patients and identified a cut off of 1.50 to correlate bax/bcl-2 ratio with well-established clinical and biological prognosticators. (haematologica.org)
  • The authors ask whether disparate results of recent consensus conferences, which ``good old'' clinical markers, if optimally analysed, might have attempted, using simple criteria, to define ``low- have a similar discriminating power with regard to breast risk'' patients for whom adjuvant chemotherapy should cancer prognosis as the microarray gene expression pro- not be recommended. (lu.se)
  • Our findings suggest an important contribution of tumor markers in the diagnosis and prognosis of these malignancies, as well as in treatment planning. (bvsalud.org)
  • Furthermore, in some tumors we identified a breakpoint between markers intragenic and extragenic to the retinoblastoma gene (Rb1) on chromosome 13q, suggesting that tumor suppressor genes other than or in addition to Rb1 may be involved in pituitary tumorigenesis. (ox.ac.uk)
  • In the study, published today in the journal Translational Psychiatry, Redei and her team developed a test that looks for markers in the blood of teens with major depressive disorder. (go.com)
  • The aim of the present review is to unravel the progress in biomarker discovery, discussing the potential applications of available biological, imaging, and neurophysiological markers. (unimi.it)
  • A growing number of researches have tried to understand the nature of human behavior by adding biological factors, especially exposure to the hormone testosterone. (bvsalud.org)
  • Table 2 presents resilience factors derived from a recent review of psychosocial, biological, and genetic research. (psychiatrictimes.com)
  • Individual differences in responses to trauma may be determined by a complex interplay between psychological, behavioral, social, and biological factors. (psychiatrictimes.com)
  • There are strong expectations that biological tumour factors undergo quality assessment and control. (lu.se)
  • Thus, neural variability may be an underlying biological contributor to well established behavioral and neural deficits found in poor readers. (biggerbetterbrains.com)
  • This article aims to demonstrate an experimental design in the area of behavioral economics and the inclusion of the research based cognitive bias of the 2D:4D ratio biological marker (Fernandes et al. (bvsalud.org)
  • Demographic characteristics, two biological variables (A1C and non-HDL cholesterol), and four behavioral management measures (kilocalories, calories of saturated fat, number of fruit and vegetable servings, and minutes of physical activity) were assessed. (diabetesjournals.org)
  • Allelic deletion in pituitary adenomas reflects aggressive biological activity and has potential value as a prognostic marker. (ox.ac.uk)
  • Conse- markers could improve prognostic assessments and help quently, one might speculate that resources could be more to better discriminate which subjects are likely to re- profitably spent for the promotion of quality assurance spond to the various tailored systemic treatments. (lu.se)
  • Tracking and diagnosing ASD can be difficult, since there is no single biological marker, and diagnostic criteria have recently changed. (cdc.gov)
  • In the past, transla- progesterone receptor (PgR) expression, and all of the tional research focused on single biological markers following features: pT 6 2 cm, grade I, age P 35 years which could putatively discriminate patients' prognosis should be considered in this low-risk category, whereas or treatment response. (lu.se)
  • An interesting finding Licis shared from her research was that underlying biological differences associated with sleep were observed in these populations. (hcplive.com)
  • Co-dominant markers can be used in mapping, to identify particular locations within a genome and can represent differences in phenotype. (wikipedia.org)
  • While sex refers to biological differences and gender refers to sociocultural effects, these terms are often used interchangeably, and most studies only consider their combined effects in a binary framework comparing two sexes/genders. (bristol.ac.uk)
  • Perhaps the weak link in the approach of the tient outcome is also highly variable and depends on Lund group is their faith in the reproducibility of biological differences among the tumours. (lu.se)
  • By the from these conventional markers to determine individual same token, within the moderate/high-risk groups, pa- prognosis [6]. (lu.se)
  • Dr. Horvath showed that progeria-affected kids who have undeniable biological aging have young epigenetic and chronological ages. (rechargebiomedical.com)
  • We aim to develop a tool to distinguish gender from sex using epigenetic markers (chemical alterations to DNA that can be readily measured in biological samples such as blood). (bristol.ac.uk)
  • For another example, some proteins can be molecular markers of Alzheimer's disease in a person from which they are taken. (wikipedia.org)
  • Researchers with an international consortium looking to understand the long-term consequences of Covid-19 on the central nervous system are finding memory issues and biological markers similar to those seen in Alzheimer's disease patients. (cbs58.com)
  • In additional research presented at the conference, Dr. Thomas Wisniewski, a professor of neurology at New York University Grossman School of Medicine, and colleagues found that Covid-19 patients over the age of 60 had biological blood markers also found in Alzheimer's patients. (cbs58.com)
  • Biological monitoring of chemical exposure in the workplace : guidelines. (who.int)
  • 1991. Documentation of the threshold limit values and biological exposure indices. (cdc.gov)
  • Threshold limit values for chemical substances and physical agents and biological exposure indices for 1997. (cdc.gov)
  • Genomic markers as mentioned, have particular strengths and weakness, so, consideration and knowledge of the markers is necessary before use. (wikipedia.org)
  • Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. (bvsalud.org)
  • There are many types of genetic markers, each with particular limitations and strengths. (wikipedia.org)
  • Genetic markers can aid in the development of new novel traits that can be put into mass production. (wikipedia.org)
  • Molecular markers may be non-biological. (wikipedia.org)
  • Molecular markers are used in molecular biology and biotechnology to identify a particular sequence of DNA in a pool of unknown DNA. (wikipedia.org)
  • Molecular markers are effective because they identify an abundance of genetic linkage between identifiable locations within a chromosome and are able to be repeated for verification. (wikipedia.org)
  • When using molecular markers to study the genetics of a particular crop, it must be remembered that markers have restrictions. (wikipedia.org)
  • These novel traits can be identified using molecular markers and maps. (wikipedia.org)
  • One example of using molecular markers in identifying a particular trait within a plant is, Fusarium head blight in wheat. (wikipedia.org)
  • A close relationship was found between this property and infection with the type 2 strains and it is hoped that this observation may be used as a simple and reliable biological marker for the differentiation of HVH type 1 and type 2. (microbiologyresearch.org)
  • Biological markers for differentiation of herpes-virus strains of oral and genital origin. (microbiologyresearch.org)
  • A temperature marker test for differentiation of strains of herpesvirus hominis. (microbiologyresearch.org)
  • Among new markers, growth differentiation factor 15 and the mid-regional part of the prohormone of adrenomedullin, have shown some promising results. (degruyter.com)
  • I still maintain that the other markers except epigenetics tend to deteriorate because of telomere erosion in stem cells but there is no denial of the predictive value of mileage in all but the progeric kids affected with telomeropathies. (rechargebiomedical.com)
  • The research must include quality human studies that meet specific criteria and biological explanations for the findings. (aicr.org)
  • The impact of yoga on neurodegenerative diseases have revealed that it reverses memory loss, reduce anxiety, depression and stress, the biological indicators of disease. (yogahealthandhealing.com)
  • Saudi Journal of Biological Sciences , 28 (1), 707-716. (pucv.cl)
  • The Department of Biological Sciences includes a wide range of specializations and, in order to be appointed, a person must have sufficient knowledge in the discipline of the course to interpret the course material, as demonstrated by either having above average performance in an equivalent or related course from an undergraduate or graduate degree, or through graduate-level research in the subject area. (sfu.ca)
  • What are the biological and other reliable indicators to suggest that doing asanas, pranayama, and meditation could reduce or treat wide range of life style disorders are discussed. (yogahealthandhealing.com)
  • 1990. Subcommittee report on biological indicators of organ damage. (cdc.gov)
  • Co-dominant markers are more beneficial because they identify more than one allele thus enabling someone to follow a particular trait through mapping techniques. (wikipedia.org)
  • Similarly, biological marker of stress were not affected. (nature.com)
  • 1974. In: Biological handbooks: Biology data book, Volume III, second edition. (cdc.gov)
  • Are you disappointed to learn that I believe the best measurement of biological age is chronological age? (rechargebiomedical.com)
  • Oxidative DNA damage and its repair: Mechanisms, measurement and biological consequences. (nist.gov)
  • Eotaxin-1 is a chemokine described as a marker of ageing, which also appear to increase with cognitive deficits and neurogenesis. (cambridge.org)
  • Besides cardiac troponin, no other markers have consistently been shown to be useful for selection of specific treatments. (degruyter.com)
  • Mills said the identification of 17 pleiotropic loci -- specific sites in the genome which may affect the expression of a number of genes and influence a range of biological pathways, in this case affecting both prostate cancer and cardiovascular disease risk -- was a key finding. (sciencedaily.com)
  • However, given that ADEM lacks a specific identified biological marker rendering a reliable laboratory diagnosis, long-term follow-up is important as there are instances where an illness initially diagnosed as ADEM is ultimately replaced with a diagnosis of MS. (medscape.com)
  • These markers allow for the amplification of particular sequence within the genome for comparison and analysis. (wikipedia.org)
  • And there are no objective, biological measures for evaluating them for depression. (go.com)
  • By studying rats that had genetic and environmental predispositions for depression, the researchers were able to pinpoint 26 markers of major depression. (go.com)
  • They looked for these markers in the blood of 28 human teenagers, ages 15 to 19, half with depression and half without. (go.com)
  • They found that 11 of the markers showed up in the depressed teens but not in teens without depression. (go.com)
  • Redei said her test is different because it identifies blood markers not previously linked to depression. (go.com)
  • Their duration of benefit and availability to the molecular characteristics of pathogens, such as viru- appears limited at the biological level, a constraint not seen lence, transmissibility, and survival fitness, which are with therapies for other disease conditions. (cdc.gov)
  • Qualitative traits (requires less than 2 genes) such as color, can be identified using MAS (marker assisted selection). (wikipedia.org)
  • This study was designed to test the hypothesis that genetic deletions are a marker of invasive behavior and to identify the loci most commonly involved. (ox.ac.uk)
  • Researchers found biological markers in the blood of 14 depressed teenagers. (go.com)
  • For instance, a RAPD marker is dominant (identifying only one band of distinction) and it may be sensitive to reproducible results. (wikipedia.org)
  • RAPD's may only need 0.02ug of DNA while an RFLP marker may require 10ug of DNA extracted from it to produce identifiable results. (wikipedia.org)
  • Results of SSR markers show that genotype MR-2 was similar to MR-1 and RK-2 with 70.8 and 42.9% similarity, whereas genotype was similar to RK-2, MR-1 and MR-2 with 63.9, 43.2 and 42.9% similarity, respectively. (pucv.cl)
  • That will allow us to differentiate between a normal situation and disease," says Maria Eugenia Inda, a Pew Postdoctoral Fellow in MIT's Department of Electrical Engineering and Computer Science (EECS) and Department of Biological Engineering (BE). (mit.edu)
  • Once a desired marker is found, it is able to be followed within different filial generations. (wikipedia.org)
  • This was further supported by the presence of Rb protein in two of four tumors where the genetic loss extended to include the intragenic marker D13S153. (ox.ac.uk)
  • This period is characterized by a range of biological and hormonal changes that can lead to symptoms similar to, but often milder than, those experienced during menopause. (bewellbuzz.com)
  • The purpose of hair collection is to obtain a suitable biological sample to determine total mercury levels in hair. (cdc.gov)
  • An identifiable marker may help follow particular traits of interest when crossing between different genus or species, with the hopes of transferring particular traits to offspring. (wikipedia.org)
  • A team of researchers led by Dr. Jayakrishna Ambati at the University of Kentucky has discovered a biological marker for neovascular age-related macular degeneration (AMD). (eyedocnews.com)
  • If you want to learn why telomeres are still one of the most useful markers of aging in both prematurely and normally aging people, watch this video. (rechargebiomedical.com)
  • Don't let people ignore the biological hazard present in your facility. (quill.com)
  • This graph shows the total number of publications written about "Biological Markers" by people in UAMS Profiles by year, and whether "Biological Markers" was a major or minor topic of these publications. (uams.edu)
  • Below are the most recent publications written about "Biological Markers" by people in Profiles over the past ten years. (uams.edu)
  • Moreover, many people view the genome as a means to better understand one's ancestral past and as a window to their biological future. (cdc.gov)
  • Literature data has already shown that treatment with inhaled or oral corticosteroids as well as with biological treatment such as monoclonal humanized anti-IgE antibody is able to decrease the level of FeNO in children with asthma and allergic rhinitis [ 13 ]. (biomedcentral.com)
  • Objective To evaluate whether including a test for faecal calprotectin, a sensitive marker of intestinal inflammation, in the investigation of suspected inflammatory bowel disease reduces the number of unnecessary endoscopic procedures. (bmj.com)
  • Non-biological markers are often used in environmental studies. (wikipedia.org)
  • currently, SNP markers have turned out to be a potential tool in breeding programs in several crops. (wikipedia.org)
  • The marker, a receptor known as CCR3, shows strong potential as a means for both the early detection of the disease and for preventive treatment. (eyedocnews.com)