• Research shows that factors and changes in the body (biological), the mind (psychological), and a person's experiences with others along with the conditions in their environment (social) are all contributors to an individual's experience of pain. (nih.gov)
  • Psychological factors are things like mood and stress. (nih.gov)
  • This essay will compare two theoretical explanations for addiction, including a psychological theory, and a biological theory. (bartleby.com)
  • Biological, psychological, behavioral, and social factors may put men at disproportionate risk of death. (cdc.gov)
  • It probably involves interactions between biological and psychosocial factors and pruritus-specific risk factors as well as mechanisms shared with other persistent somatic symptoms addressed in other projects of the SOMACROSS Research Unit (RU). (iasp-pain.org)
  • We expect that psychosocial factors relevant to the persistence of symptoms such as fatigue and pain may also show associations to CP. (iasp-pain.org)
  • We describe an approach that considers biological and psychosocial factors that affect men's health and how these factors may intersect. (cdc.gov)
  • In today's post, I want to focus on the most common bottlenecks in biological wastewater treatment systems. (biologicalwasteexpert.com)
  • Let's take a closer look at what's happening with biological sulfate treatment in Minnesota and what it means for your wastewater projects. (barr.com)
  • In this study, a pilot wastewater treatment plant was used to evaluate the co-treatment of biological-staining residues and domestic wastewater under non-sterile conditions. (scirp.org)
  • Biological factors associated with pain include things like brain function and genetics. (nih.gov)
  • The researchers plan to continue using epigenetic data, along with information on genetics, environment, and lifestyle to better understand how these factors interact and contribute to disease risks. (nih.gov)
  • Although some progress has been made in identifying behavioral risk factors for sexual transmission of human immunodeficiency virus (HIV), little is known about the biologic determinants of infectivity and susceptibility. (nih.gov)
  • Biological therapies in cancer treatment will nearly double in the next five years, and reach more than $66 billion by 2019. (bccresearch.com)
  • 2019. Methylation-based biological age and breast cancer risk. (nih.gov)
  • It has also been possible to conduct longitudinal studies to identify biomarkers and contribute to improve understanding of the peripheral biological changes accompanying conversion from prodromes to full-blown psychosis. (cam.ac.uk)
  • Primary outcome criteria were clinical depression ratings (HAM-D scale), vital signs, classical cardiovascular risk factors and inflammatory biomarkers which were compared between MDD patients and healthy controls. (uni-muenchen.de)
  • Environmental health scientists say that more knowledge about such biological indicators - called biomarkers of effect - could shed light on the progression of certain diseases and spur medical advances. (nih.gov)
  • Hepatocyte Growth Factor (HGF) is a multifunctional, heparin-binding factor that stimulates the proliferation of liver cells. (sigmaaldrich.com)
  • Human basic fibroblast growth factor (hBFGF) is a heparin-binding growth factor and stimulates the proliferation of a wide variety of cells and tissues causing survival properties and its stability and biological activity improvements have received much attention. (ac.ir)
  • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. (nih.gov)
  • In this review, we analyze the clinical characteristics and outcomes of autoimmune diseases developing after biological therapies through a baseline Medline search as one of the objectives of the BIOGEAS project, created by the Spanish Society of Internal Medicine. (nih.gov)
  • Understanding factors that mediate the regeneration of neurons and the growth of axons is crucial for the development of breakthrough therapies for blinding diseases. (nih.gov)
  • The market for innovative biological therapies in cancer treatment reached more than $51 billion in 2014. (bccresearch.com)
  • Biological Therapies for Cancer: Technologies and Global Markets provides a detailed overview and thorough analysis of the present and future global market for cancer biotherapeutics. (bccresearch.com)
  • The latest update of our registry (15 July 2009) included more than 800 cases of autoimmune diseases secondary to biological therapies, including a wide variety of both systemic (lupus, vasculitis, sarcoidosis and antiphospholipid syndrome) and organ-specific (interstitial lung disease, uveitis, optic neuritis, peripheral neuropathies, multiple sclerosis and autoimmune hepatitis) autoimmune processes. (nih.gov)
  • Previous studies have shown that cancer cells could behave in the form of adaptation to hypoxia in tumor growth, which could result in their biological changes and determine their responses to the therapies. (nih.gov)
  • Researchers found that certain biological differences didn't predict whether someone would lose more weight from a low-fat or low-carbohydrate diet. (nih.gov)
  • However, because critical scientific gaps remain in our understanding of underlying biological mechanisms that could contribute to these differences, it is difficult to develop targeted therapeutic regimens for those in greatest need. (nih.gov)
  • Recent studies of other diseases demonstrating racial/ethnic disparities in prevalence and severity have identified biological factors as possible reasons for differences in disease outcomes. (nih.gov)
  • To date, transmission patterns of Streptococcus mutans from mother to child and between family members have been characterized, but no distinct biological differences in caries pathways have been documented for different racial or ethnic groups. (nih.gov)
  • In our opinion, a multivariate analysis is the only appropriate statistical method capable of revealing important details concerning potential gender differences in organ donation and enabling comprehension of the tight interdependence between biological and social variables. (alliedacademies.org)
  • However, it appears that there are many factors that must be taken into consideration before proper gender differences can be identified. (alliedacademies.org)
  • I conclude that citation frequency differs not only among biological sub-disciplines such as ecology and taxonomy, but also among taxonomic papers on highly similar topics, and that these latter differences largely depend on the organismal group (cryptogams vs. vascular plants and species-rich vs small genera and families) and the geographic region concerned. (lu.se)
  • Mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR) gene in lung cancers are associated with increased sensitivity of these cancers to drugs that inhibit EGFR kinase activity. (nih.gov)
  • Transcription factors are essential for the regulation of gene expression and are, as a consequence, found in all living organisms. (wikipedia.org)
  • The number of transcription factors found within an organism increases with genome size, and larger genomes tend to have more transcription factors per gene. (wikipedia.org)
  • Hence, the combinatorial use of a subset of the approximately 2000 human transcription factors easily accounts for the unique regulation of each gene in the human genome during development. (wikipedia.org)
  • Depending on the transcription factor, the transcription of the adjacent gene is either up- or down-regulated. (wikipedia.org)
  • Transcription factors use a variety of mechanisms for the regulation of gene expression. (wikipedia.org)
  • This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. (nih.gov)
  • In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. (wikipedia.org)
  • Orthologous to human ARL6IP6 (ADP ribosylation factor like GTPase 6 interacting protein 6). (nih.gov)
  • A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit. (nih.gov)
  • Insulin-like growth factor 2 ( IGF-2 ) is one of three protein hormones that share structural similarity to insulin . (wikipedia.org)
  • The diagnostic value of serum insulin-like growth factor binding protein 7 in gastric cancer. (nih.gov)
  • Mammalian cells have 2 additional ER stress sensors: the membrane-bound transcription factor ATF6 and the receptor-type protein kinase PERK. (nature.com)
  • The researchers speculated that biological age might be tied to environmental exposures. (nih.gov)
  • However, we do not yet know how exposures and lifestyle factors may affect biological age or whether this process can be reversed. (nih.gov)
  • The purpose of this initiative is to encourage studies aimed at understanding biological factors that mediate the increased prevalence and severity of Dental, Oral, and Craniofacial (DOC)-related diseases and conditions in oral health disparities populations. (nih.gov)
  • A tree growing is like a horse and cart system moving forward down the road," says William Anderegg, an associate professor in the U's School of Biological Sciences and principal investigator of the study. (utah.edu)
  • Extracting wood cores from tree stems and measuring the width of each ring on these cores essentially lets us reconstruct past tree growth," says Antoine Cabon, a postdoctoral scholar in the School of Biological Sciences and lead author of the study. (utah.edu)
  • In addition, phthalates are a common environmental exposure (see sidebar), which when present in high concentrations in the body have been associated with sperm epigenetic profiles in biological pathways known to be important for early embryonic development. (nih.gov)
  • Gender disparities and organ transplantation are a prime illustration of how biological and social factors interact. (alliedacademies.org)
  • Ortona A. Gender disparities and organ transplantation are a prime illustration of how biological and social factors interact. (alliedacademies.org)
  • Discuss to what extent cognitive and biological factor interact in emotion The cognitive level of analysis (CLOA) is a way of understanding the mind and its processes and how these purposes guide human behavior. (bartleby.com)
  • von Willebrand factor (VWF), a plasma glycoprotein that is essential for normal hemostasis, is heavily glycosylated, containing 13 N-linked and 10 O-linked glycans. (nih.gov)
  • They used three different measures, called epigenetic clocks, to develop biological age estimates. (nih.gov)
  • We investigated biological behaviors such as cell cycle, proliferation, radiation sensitivity, apoptosis and migration, hypoxia signal pathway in the lung cancer cells treated with chronic intermittent hypoxia, as well as the role of hypoxia inducible factor 1 there, hypoxia-inducible genes analyzed by real-time RT-PCR chip in H446 cells treated with the model. (nih.gov)
  • Studies have suggested two potential biological factors for success with different diets: metabolic predisposition and genetic predisposition. (nih.gov)
  • As the global population shifts toward more older people than children, investigators want to understand the environmental and genetic factors that influence how "successfully" an individual ages. (nih.gov)
  • The study was designed to identify environmental and genetic risk factors for breast cancer. (nih.gov)
  • We found that if your biological age is older than your chronological age, your breast cancer risk is increased," said corresponding author Jack Taylor, M.D., Ph.D. , head of the NIEHS Molecular and Genetic Epidemiology Group. (nih.gov)
  • There are still many other factors involved, such as environment, values, morals, and genetic predisposition, these factors are not even considered and will most likely be crossed without regard to the consequences until treatment and recovery are the only options left. (bartleby.com)
  • However, they don't rule out the idea that further research will identify genotypes or other factors that do predict responses to low-fat and low-carb diets. (nih.gov)
  • Because there is very limited information on biological/cellular aspects that affect sexual transmission, there is a need to stimulate research in this area. (nih.gov)
  • The objective of this program announcement is to stimulate research on the biological factors influencing HIV sexual transmission. (nih.gov)
  • Examples of research studies encouraged include, but are not limited to, the following: o Biological mechanism of cell-free versus cell- associated viral entry across the genital mucosal barrier, including such aspects as virus variability, tropism, and stability. (nih.gov)
  • He co-manages the International Research Network Dev-O-Psy exploring the biological bases of early phases of psychosis. (cam.ac.uk)
  • The research provides more evidence that biological age is a real concept and can be used in assessing health outcomes,' Kresovich said. (nih.gov)
  • As regulations and research evolve, we expect biological sulfate removal to become increasingly viable as a treatment alternative for Minnesota industries and utilities. (barr.com)
  • The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. (nih.gov)
  • Multiple studies have also found that the circadian rhythm - a kind of 24-hour biological clock that governs mood, appetite and sleepiness - can affect athletic or fitness performance. (thestar.com.my)
  • Lots of factors can directly affect both photosynthesis and cell growth rate, including temperature and the availability of water or nutrients. (utah.edu)
  • This figure shows how sulfur changes between sulfate, sulfide, and sulfur, and related reactions that affect biological sulfate removal technologies. (barr.com)
  • Biological age, which is a DNA-based estimate of a person's age, is linked to future development of breast cancer, according to NIEHS scientists in a study published online February 22 in the Journal of the National Cancer Institute. (nih.gov)
  • Here we aim to identify psychosocial and biological factors and their interactions which might be associated with the persistence of CP with and without immunologic/inflammatory origin, that is, atopic dermatitis and pruritus on non-inflamed skin. (iasp-pain.org)
  • Transcription factors bind to either enhancer or promoter regions of DNA adjacent to the genes that they regulate. (wikipedia.org)
  • Other transcription factors differentially regulate the expression of various genes by binding to enhancer regions of DNA adjacent to regulated genes. (wikipedia.org)
  • purified recombinant mouse hepatocyte growth factor receptor extracellular domain expressed in insect Sf 21 cells. (sigmaaldrich.com)
  • Bangla version of the Composite Scale of Morningness: Factor invariance and validity with sleep habits, mood and mental health. (ucm.es)
  • Levoleucovorin and leucovorin are analogs of tetrahydrofolate (THF) and are able to bypass DHFR reduction to act as a cellular replacement for the co-factor THF. (rcsb.org)
  • abstract = "Based on my experience and analyses of citation frequencies of papers published in various biological journals, I discuss the use of citation counts and journal Impact Factors as measures of scientific quality. (lu.se)
  • They also found that the psychophysiological pattern of anxiety, poor concentration, and biological indicators of stress in community members affected remained subclinically elevated for 6 years and only returned to normal levels 10 years after the accident. (cdc.gov)
  • Even though donor-recipient sex mismatch, according to biological considerations, appears undesirable in female recipients, the effect of sex mismatch on transplant outcome is still up for debate. (alliedacademies.org)
  • The two-factor theory support the interaction between biological and cognitive factors in the following ways: - Physiological arousal is imperative for the experience of emotion, but this only is labeled through a cognitive evaluation of the situation. (bartleby.com)
  • Biologic factors may contribute to other cancer health disparities, such as colorectal cancer and prostate cancer in African-Americans ( National Cancer Institute ). (nih.gov)
  • Biosimilars are entering an important period of development, and it is anticipated that the market will evolve from 2014 to 2024 along with many new players in the biological cancer drug space. (bccresearch.com)
  • NIEHS scientists reported that women whose DNA shows biological age older than their chronological age face a higher risk of breast cancer. (nih.gov)
  • If a woman's biological age is older than her chronological age, she has an increased risk of developing breast cancer. (nih.gov)
  • The study showed that for every five years a woman's biological age was older than her chronological or actual age, known as age acceleration, she had a 15 percent increase in her chance of developing breast cancer. (nih.gov)
  • If your biological age is younger than your chronological age, you may have decreased risk of developing breast cancer. (nih.gov)
  • Because age is the leading risk factor for breast cancer, he thought that age acceleration might be associated with higher breast cancer risk. (nih.gov)
  • Kresovich suggested that using DNA methylation to measure biological age might help scientists better understand who is at risk for developing cancer and other age-related diseases. (nih.gov)
  • Folic acid is particularly important during phases of rapid cell division, such as infancy, pregnancy, and erythropoiesis, and plays a protective factor in the development of cancer. (rcsb.org)
  • Zack, Gamm, and their teams plan to study precursor photoreceptor cells derived from human stem cells to determine what factors help coax them into becoming fully developed and connected photoreceptor cells. (nih.gov)
  • There are approximately 2800 proteins in the human genome that contain DNA-binding domains, and 1600 of these are presumed to function as transcription factors, though other studies indicate it to be a smaller number. (wikipedia.org)
  • Therefore, approximately 10% of genes in the genome code for transcription factors, which makes this family the single largest family of human proteins. (wikipedia.org)
  • Wu X, Li X, Zeng Y, Zheng Q, Wu S. Site-directed PEGylation of human basic fibroblast growth factor. (ac.ir)
  • Solid-phase N-terminus PEGylation of recombinant human fibroblast growth factor 2 on heparin-sepharose column. (ac.ir)
  • Scientists used these clocks to estimate biological age, which could then be compared with chronological age. (nih.gov)
  • The team is now using their data to explore other factors that may influence an individual's success with weight loss. (nih.gov)
  • Social factors include things like having (or not having) a support system or experiencing biased care. (nih.gov)
  • It will also be argued that not only is a social constructionism perspective necessary when determining sexuality but it is also more important that biological determinism. (bartleby.com)
  • It is believed to be a major fetal growth factor in contrast to insulin-like growth factor 1 (IGF-1), which is a major growth factor in adults. (wikipedia.org)
  • As a result, journals with a broad biological scope face difficulties in competing in terms of Impact Factors, and thus in competing for the best manuscripts, with journals specialized on particular sub-disciplines that attract many citations. (lu.se)
  • The findings for each risk factor except age are summarized in Table 3 and discussed separately in the following sections. (medscape.com)
  • Biological agents are increasingly used for a rapidly-expanding number of rheumatic and systemic autoimmune diseases, with a growing number of reports of the paradoxical induction of autoimmune processes, overwhelmingly associated with anti-TNF agents. (nih.gov)
  • Each set of factors affects and impacts one another. (nih.gov)
  • A team led by Dr. Christopher D. Gardner of Stanford University explored the influence of certain biological factors on the success of weight loss with low-fat and low-carbohydrate diets. (nih.gov)
  • We can seize this moment to reimagine and redesign our health care and public health systems to consider the many factors that influence men's health. (cdc.gov)
  • It was found that such changes were related to hypoxia inducible factor 1, alpha subunit (HIF-1α). (nih.gov)
  • It has been found that transcription factors (TF) dysregulation, leading to the significant expression modifications of genes, is a widely distribut. (ccb.org.co)
  • Data suggest that several factors may contribute to the development of pyromania and that the interaction of environmental and biological factors may play a role. (medicalnewstoday.com)
  • Factors underpinning the shift to eveningness during early adolescence: Pubertal development and family conflicts. (ucm.es)
  • Precise detection of cardiovascular risks in MDD beyond classical risk factors is warranted to allow effective prophylaxis and treatment of both conditions. (uni-muenchen.de)