• Moreover, analysis showed that while expression of many genes on the monosomic Ch5 is altered in accordance with the chromosome ploidy, expression of a large fraction of genes is increased to the normal diploid level, presumably compensating for gene dose. (biomedcentral.com)
  • In light of data pointing to the importance of Ch5 in C. albicans drug resistance, there is a growing need to better understand the control of Ch5 ploidy and regulation of genes on this chromosome. (biomedcentral.com)
  • Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum. (cornell.edu)
  • TE-rich genomic islands in expanded fungal ( P. fijiensis , L. maculans ) and oomycete ( Phytophthora infestans ) genomes carry genes that code for lineage-specific, putative small, secreted proteins. (biomedcentral.com)
  • Experimentally, we demonstrate the transfer of two LS chromosomes between strains of F. oxysporum , converting a non-pathogenic strain into a pathogen. (nature.com)
  • The major human fungal pathogen Candida albicans possesses a diploid genome, but responds to growth in challenging environments by employing chromosome aneuploidy as an adaptation mechanism. (biomedcentral.com)
  • Candida albicans is an opportunistic fungal pathogen that is part of the normal microbial community of the digestive tract and genitalia of humans. (biomedcentral.com)
  • Here, we address this by assembling a global thousand-genome panel of Zymoseptoria tritici, a major fungal pathogen of wheat reported in all production areas worldwide. (bvsalud.org)
  • Transformation of your oomycete pathogen Phytophthora megaspema f. sp.gEycinea takes place of the DNA consolidation into solitary or multiple chromosomes. (bulle-dair-coiffure.fr)
  • Simchen.An initial chromosomal part with major roles inside the yeast chromosome I11 meiotic disjunction, recombination and double strand holiday breaks. (realprowa.com)
  • The JGI Annotation Pipeline was used to add additional functional annotation to the author's chromosomes and proteins. (doe.gov)
  • These findings put the evolution of fungal pathogenicity into a new perspective. (nature.com)
  • Divergent and Convergent Evolution of Fungal Pathogenicity. (doe.gov)
  • Vertebrate chromosomes are mosaic structures containing large conserved segments that can reside in different linkage groups in different species. (biomedcentral.com)
  • 2006). Karyotypic relationships among the tribes of Hypostominae (Siluriformes: Loricariidae) with description of XO sex chromosome system in a Neotropical fish species. (geneticsmr.com)
  • 2019. Comparative Chromosome Mapping of Musk Ox and the X Chromosome among Some Bovidae Species. (farre-evogenomicslab.com)
  • Common bunt, caused by two fungal species, Tilletia caries and Tilletia laevis , is one of the most potentially destructive diseases of wheat. (mdpi.com)
  • Genomic studies on fungal species with hydrolytic activity have gained increased attention due to their great biotechnological potential for biomass-based biofuel production. (biomedcentral.com)
  • We also show that Pds5 co-localizes with cohesin on chromosomes, that the chromosomal association of Pds5 and cohesin is interdependent, that Scc1 recruits Pds5 to chromosomes in G1 and that its cleavage causes dissociation of Pds5 from chromosomes at the metaphase-to-anaphase transition. (nih.gov)
  • Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog ofmetazoan p300/CBP. (embl.de)
  • Rtt109, also known as KAT11, is a recently characterized fungal-specific histone acetyltransferase (HAT) that modifies histone H3 lysine 56 (H3K56) to promotegenome stability. (embl.de)
  • This family contains the fungal KAT11 protein (previously known as RTT109) which is required for H3K56 acetylation. (embl.de)
  • Genome-wide association study for Chagas Cardiomyopathy identify a new risk locus on chromosome 18 associated with an immune-related protein and transcriptional signature. (cdc.gov)
  • Transfers of a single gene, a complete metabolic pathway 10 , whole chromosomes 11 or even cases of the integration of almost complete genomes from bacterial endosymbionts into their eukaryotic hosts 12 have been described. (nature.com)
  • 2014) Convergent bacterial microbiotas in the fungal agricultural systems of insects . (doe.gov)
  • 1997. Shared themes of antigenic variation and virulence in bacterial, protozoal, and fungal infections. . (cornell.edu)
  • Our analysis revealed lineage-specific (LS) genomic regions in F. oxysporum that include four entire chromosomes and account for more than one-quarter of the genome. (nature.com)
  • These artificial chromosomes are used extensively in molecular biology for the construction of comprehensive genomic libraries of higher organisms. (harvard.edu)
  • Moreover, as the first gapless genome assembly in the genus Saccharomycopsis including members with desirable traits for bioconversion, the unique genomic features of S. fibuligera and its hybrid will provide in-depth insights into fungal genome dynamics as evolutionary adaptation. (biomedcentral.com)
  • Our results are consistent with a model wherein chromosome-wide elevation of H4 acetylation mediated by the NuA4 complex plays a role in increasing gene expression in compensation for gene dose and adaption to growth in a toxic environment. (biomedcentral.com)
  • These observations led us to propose that in C. albicans , transcriptional compensation for gene dose serves to facilitate the formation and maintenance of aneuploid chromosome states that are required for survival in adverse environments [ 7 ]. (biomedcentral.com)
  • Brand new HOPl gene encodes good meiosisspecific part of fungus chromosomes. (realprowa.com)
  • Previous analyses revealed that TE-mediated gene amplifications can have variable effects on fungal genomes, from inactivation of function to production of multiple active copies. (biomedcentral.com)
  • Transfer of LS chromosomes between otherwise genetically isolated strains explains the polyphyletic origin of host specificity and the emergence of new pathogenic lineages in F. oxysporum . (nature.com)
  • Ultimately, I hope to offer the community of soil microbial ecologists a game-changing new tool to study chemistry and ecosystem functions of microbial metabolites (including 'fungal warfare' compounds) in more realistic settings. (lu.se)
  • Supercharging SIP in the Fungal Hyphosphere Applying high-throughput stable isotope probing to the study of a particular fungi, researchers identified novel interactions between bacteria and the fungi. (doe.gov)
  • C. albicans normally possesses a diploid genome organized in eight pairs of chromosomes, but uses reversible loss or gain of an entire chromosome or a large part of chromosomes to survive in toxic environments that would otherwise kill cells or prevent their propagation [reviewed in 1 , 2 ]. (biomedcentral.com)
  • Chromosomes in which fragments of exogenous DNA ranging in length up to several hundred kilobase pairs have been cloned into yeast through ligation to vector sequences. (harvard.edu)
  • The seven chromosome pairs of KJJ81 subgenomes exhibit highly conserved synteny, indicating a very recent hybridization event. (biomedcentral.com)
  • A quality control worker in a feed factory developed acute disease after taking samples of cattle feed treated with phytase, a fungal-derived enzyme used to treat cattle feed to strengthen bone. (cdc.gov)
  • Comparisons between the genomes of the closely related nematodes Caenorhabditis elegans and Caenorhabditis briggsae reveal high rates of rearrangement, with a bias towards within-chromosome events. (biomedcentral.com)
  • Telomerase is mechanistically a reverse transcriptase but to the grateful genomes on which it operates it is a chromosome end-specific DNA polymerase. (rupress.org)
  • Comparative analyses revealed that a similar event occurred in five additional genomes representing the fungal genera Cercospora , Pseudocercospora and Sphaerulina . (biomedcentral.com)
  • The research projects aim to advance methods in microbiological ecology and map the development of sex chromosomes. (lu.se)
  • The loss of one Ch5 also confers laboratory resistance to the anti-fungal flucytosine, as well as resistance to toxic sugar l -sorbose, which kills C. albicans in a manner similar to caspofungin or other frontline drugs from the echinocandin class [reviewed in 3 ]. (biomedcentral.com)
  • These chips reveal fungal cells for microscopic analysis. (lu.se)
  • Cells lacking Rtt109 or expressing rtt109 mutants withalterations at a conserved aspartate residue lose H3-K56 acetylation and exhibit increased sensitivity toward genotoxic agents, as well as elevated levels ofspontaneous chromosome breaks. (embl.de)
  • The Cajal body is an intriguing nuclear structure present in a great variety of plant, animal, and some fungal cells. (rupress.org)
  • For example, we have shown that C. albicans adapts to growth on the toxic sugar l -sorbose by transitioning to a state in which one chromosome (chromosome 5, Ch5) becomes monosomic. (biomedcentral.com)
  • This graph shows the total number of publications written about "Chromosomes, Artificial, Yeast" by people in Harvard Catalyst Profiles by year, and whether "Chromosomes, Artificial, Yeast" was a major or minor topic of these publication. (harvard.edu)
  • Many techniques have been devised to capture the architectural information within whole genome [ 1 - 9 ], among which the High-throughput Chromosome Conformation Capture (Hi-C) technique has gained widespread adoption. (biomedcentral.com)
  • Chromosome level ordering of the scaffolds was achieved by anchoring the assemblies either to a genetic map for Fv (ref. 7 ), or an optical map for Fol ( Supplementary Information A and Supplementary Table 2 ). (nature.com)
  • Estimation of rates of intrachromosomal to between-chromosome rearrangements showed that both were very frequent (approximately fourfold greater than that observed in D. melanogaster ). (biomedcentral.com)
  • These data show a significant chromosome-wide elevation in histone H4 acetylation on the mCh5, but not on any other chromosome. (biomedcentral.com)
  • Immunofluorescence studies suggest that NEK7 is cytoplasmic and located on chromosome 1 (1). (signalchem.com)
  • et que les fruits en développement ont un impact négatif sur les dynamiques des réserves en azote et en zinc dans les branches ainsi que sur la production des fleurs femelles l'année suivante. (cnrs.fr)
  • 2011. An improved consensus linkage map of barley based on flow-sorted chromosomes and single nucleotide polymorphism markers. (triticeaecap.org)
  • When this RNA later leaves, its promotional job done, a little spot of single-stranded template DNA is exposed-a dangerous dangle, potentially activating chromosome and even cellular destruction. (rupress.org)
  • It will give me the opportunity to assemble a research team that will work together both towards the novel spectroscopy method development, but also addressing specific research questions and pushing the frontier in soil fungal biology. (lu.se)
  • In mammals, whether an individual develops as a male or female depends on its sex chromosome constitution: those with a Y chromosome become males because of the development of the embryonic gonad into a testis. (plos.org)