• To this end the in vitro activities of daptomycin, linezolid, and rifampicin on S. epidermidis biofilms were accessed, using these antibiotics at MIC and peak serum concentrations. (unesp.br)
  • However, considering all the parameters studied, daptomycin was considered the most effective antibiotic tested, demonstrating an excellent in vitro activity against S. epidermidis biofilm cells. (unesp.br)
  • Therefore, the main aim of this study was to study the susceptibility of S. epidermidis biofilm cells to the two newer antimicrobial agents previously mentioned, and compare the results obtained with the antimicrobial effect of rifampicin, widely used in the prevention/treatment of indwelling medical device infections. (unesp.br)
  • In conclusion, this antibiotic can be strongly considered as an acceptable therapeutic option for S. epidermidis biofilm-associated infections and can represent a potential alternative to rifampicin in serious infections where rifampicin resistance becomes prevalent. (unesp.br)
  • on the other hand, rifampicin has been shown to be one of the most potent, prevalent antibiotics against S. epidermidis biofilms. (unesp.br)
  • Accordingly, the paucity of effective treatment against cells in this mode of growth is a key factor that potentiates the need for new agents active in the prevention or eradication of biofilms. (unesp.br)
  • Biofilms are one of the most widely distributed and successful modes of life on Earth," says Prof. Hans-Curt Flemming - director of the Institute for Interface Biotechnology at the University of Duisburg-Essen in Germany - in a 2016 article published in Nature Reviews Microbiology . (medicalnewstoday.com)
  • The author, who proposed this biofilm hypothesis, uses direct evidence from microscopy and from molecular techniques, presenting cogent reasons for moving beyond conventional culture methods that dominated microbiology throughout the last century. (springer.com)
  • Bill is widely regarded as the "grandfather" of biofilm microbiology. (springer.com)
  • Please go to URL http://www.bio.net and click on the 'Access the BIOSCI/bionet Newsgroups' option and then click on the BIOFILMS/bionet.microbiology.biofilms hyperlink. (bio.net)
  • If you do not see bionet.microbiology.biofilms in your newsreader within another day or two, ask your news system administrator to act on our 'newgroup' message to enable the group at your site. (bio.net)
  • You might also try the command 'g bionet.microbiology.biofilms' in rn-like newsreaders. (bio.net)
  • The complexity of biofilm activity and behavior requires research contributions from many disciplines such as biochemistry, engineering, mathematics and microbiology. (montana.edu)
  • Biofilms require a coordinated attack by researchers with expertise in everything from microbiology and immunology to materials science and mathematical modeling, Mangan explains. (sciencemag.org)
  • Citing that the techniques currently used to identify anti-biofilm activities in phage-derived proteins have the "important shortcomings" of being laborious endpoint assays that suffer from poor reproducibility, in the recent issue of Frontiers in Microbiology a team of scientists lead by Diana Gutierrez report a proof of concept study using an xCELLigence Real-Time Cell Analysis instrument to monitor the disruption of clinically important Staphylococcus aureus biofilms. (news-medical.net)
  • Furthermore, it has contributed to the field of biofilm microbiology by quantifying the BFP of each of the cultured isolates and' it has enhanced the clinical understanding of biofilms within veterinary wounds. (bl.uk)
  • Previous microbiological studies of showerhead biofilms have used culture methodology to detect and identify microbes, and have focused primarily on Legionella pneumophilia ( 7 , 8 , 9 ) and Mycobacterium avium ( 10 - 12 ). (pnas.org)
  • As illustrated in the micrographs in Fig. 1 , microbes generally were clumped and embedded in extracellular material, consistent with biofilm morphology. (pnas.org)
  • A key factor in the microbes' success on mudflats is that they live together in neighborhoods: the biofilms. (scientificamerican.com)
  • This is an excellent characteristic for health-promoting biofilms, but it's alarming when harmful microbes plant their flag in your body to start settling down. (dreddyclinic.com)
  • Your gut is uniquely suited to biofilm formation since the lining of the intestine is covered with a mucous gel-layer that protects your gut microbes. (dreddyclinic.com)
  • These biofilms are communities of microbes encased in a self-produced matrix that often contains polysaccharides, DNA and proteins. (mdpi.com)
  • Oral diseases, including caries and periodontitis, consist of biofilms* produced by microbes. (rainbow.coop)
  • The study of factors that allow manipulation of biofilm microbes in the biofilm growth state requires that reproducible biofilms by generated. (unt.edu)
  • And when pathogenic microbes form biofilms, they are. (medicalxpress.com)
  • Rather than existing in a planktonic or free-living form, evidence indicates that microbes show a preference for living in a sessile form within complex communities called biofilms. (waterstones.com)
  • Biofilms appear to afford microbes a survival advantage by optimizing nutrition, offering protection against hostile elements, and providing a network for cell-to-cell signaling and genetic exchange. (waterstones.com)
  • Unfortunately, one of the most troubling characteristics of microbes found in biofilms is a profound resistance to antimicrobial agents. (waterstones.com)
  • Clinically, researchers envision the biofilm producing microbes could be ingested in a probiotic pill. (harvard.edu)
  • Now, a group of researchers at Caltech and the University of Oxford have made progress in the fight against biofilms. (caltech.edu)
  • To better understand the fungus' biofilm capabilities, the researchers compared the biofilm mass of four strains of C auris with that of two other fungi, Candida albicans and Candida glabrata . (medscape.com)
  • In future studies, the researchers aim to better understand the mechanisms involved in preventing biofilms. (innovations-report.com)
  • For years, researchers have focused on developing antimicrobial treatments to stop the formation of biofilms, but as the statistics indicate, they have yet to find an affordable, effective solution. (infectioncontroltoday.com)
  • A team of researchers with members from the U.S., Germany and Sweden has discovered that the cellulose found in bacterial biofilms differs from the cellulose in plants. (phys.org)
  • The researchers assume that the added biofilm stimulates uniform crystal growth throughout the volume of the hybrid material. (tum.de)
  • We want researchers to know that we recognize the importance of biofilms and [want to] bring people together to work on the problem," says Dennis Mangan of the National Institute of Dental and Craniofacial Research (NIDCR), who is spearheading the effort. (sciencemag.org)
  • The goal is to understand how and why biofilms form so that researchers can identify their Achilles' heel and devise better treatments, which are badly needed. (sciencemag.org)
  • In their work , published Dec. 11 in Physical Review Letters , the researchers were able to find predictable patterns of how fluids move based on the general shapes of biofilms, insights that could find applications in many fields. (stanford.edu)
  • Within organized biofilms, the researchers found two common patterns of movement: vortexes and asters. (stanford.edu)
  • By targeting a noninfectious viral cage to biofilms, researchers developed a system for early detection and eventual destruction of these bacterial communities. (ebscohost.com)
  • To probe the anti-biofilm properties of iron ions, the researchers exposed polycarbonate films to iron-ion beams of two different energies. (natureasia.com)
  • Numerous challenges call for novel solutions and concepts of analytics, biofilm reactor design, product recovery, and scale-up strategies. (nih.gov)
  • In this review, we highlight recent advancements in spatiotemporal biofilm characterization and new biofilm reactor developments for the production of value-added fine chemicals as well as current challenges and future scenarios. (nih.gov)
  • MBBR (Moving bed biofilm reactor) is now the common name for biological treatment process invented by Professor Halvard Odegaard in Trondheim in the late eighties. (environmental-expert.com)
  • The Moving Bed Biofilm Reactor (MBBR) is one of the most advanced wastewater treatment technologies available in the world today as it combines the benefits of both the suspended and the attached growth process. (environmental-expert.com)
  • The TBR™ is an advanced MBBR™ biofilm technology is based on specially designed plastic biofilm carriers or biocarriers that are suspended and in continuous movement within a tank or reactor of specified volume. (environmental-expert.com)
  • The Moving Bed Biofilm Reactor or MBBR process is based on the aerobic biofilm principle and utilizes activated sludge and other biofilm systems. (environmental-expert.com)
  • Such limitation of bioavailability can be overcome by steady-state biofilm-based reactor. (mendeley.com)
  • In-vitro experiments such as the crystal violet microtitre plate assay and a CDC biofilm reactor were used to quantify biofilm formation. (bl.uk)
  • investigated characteristics of nitrogen removal from old landfill leachate by sequencing batch biofilm reactor (SBBR). (acronymfinder.com)
  • Enclosed in a matrix primarily consisting of polysaccharides, pathogens in biofilms are often more resistant to environmental stresses such as heat and chemical sanitizers than are their planktonic counterparts. (uga.edu)
  • Biofilm is a multidisciplinary, gold open access journal focused on hypothesis- or discovery-driven studies on microbial cells that grow in multicellular communities (including surface-attached biofilms and suspended aggregates) and demonstrate different gene expression, growth rate, behavior and appearance to those that are in planktonic (free-living) state. (elsevier.com)
  • The formation of a biofilm usually begins when a single planktonic microbe tenuously clings to a surface. (dreddyclinic.com)
  • The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single-cells that may float or swim in a liquid medium. (medicalxpress.com)
  • Methods: Mutation frequencies to resistance against mupirocin and rifampicin were determined for planktonic cultures and for biofilms generated using either a novel static biofilm model. (ebscohost.com)
  • Many years of research on biofilm and migratory shorebirds at Roberts Bank and other areas illustrate the covert yet vital role that the slime plays in the ecosystem. (scientificamerican.com)
  • Biofilm EPS, which is also referred to as slime (although not everything described as slime is a biofilm), is a polymeric conglomeration generally composed of extracellular DNA, proteins, and polysaccharides. (medicalxpress.com)
  • In simpler terms, biofilms are layers of slime that make it difficult to entirely clean and disinfect a surface. (neogen.com)
  • The structural and physiological complexity of biofilms has led to the idea that they are coordinated and cooperative groups, analogous to multicellular organisms. (nih.gov)
  • 3. The method of claim 1 wherein the step of providing a biofilm layer comprises introducing a gas into the gas compartment that diffuses through the membrane and selects gas degrading organisms in the biofilm layer. (google.com)
  • They form in pipes, in water systems, on living organisms-the first biofilm discovered was on a person's teeth-and, of course, on mud. (scientificamerican.com)
  • The engineers of mudflat biofilms are single-celled photosynthesizing organisms called diatoms. (scientificamerican.com)
  • The presence of pathogens attached to the middle-ear mucosa as a bacterial biofilm, rather than as free-floating organisms in a middle-ear effusion, has previously been suggested to explain these observations. (nih.gov)
  • According to the US Navy's Office of Naval Research, micro-fouling in the form of adhesive surface biofilms can increase drag by up to 20%, while the macro-fouling caused by larger organisms - typically barnacles - can add more than 60% overall. (naval-technology.com)
  • The Biofilm mode of growth provides such significant advantages to the members of the consortium that most organisms in important habitats are found in biofilms. (unt.edu)
  • Phototrophic biofilms can best be described as surface attached microbial communities (see also Biofilm and Chemistry of Biofilm Prevention) mainly driven by light as the energy source with phototrophic organisms clearly present. (wikipedia.org)
  • Biofilms are tricky beasts because they have a tendency to become resistant to all manner of efforts employed to eradicate them. (medicalnewstoday.com)
  • Chuanwu Xi, PhD, Assistant Professor in the Department of Environmental Health at the University of Michigan and his research team found that treated steam from a novel steam disinfection system utilizing TANCS® technology rapidly kills highly resistant biofilms with greater than 99.95 % killing efficiency in a 3 second treatment, and to a non-detectable level in a less than 10 second treatment. (prweb.com)
  • Was it better at forming a dense biofilm or was it more resistant to disinfectants than other Salmonella? (innovations-report.com)
  • This form of graphene is extremely resistant to biofilm formation, which has promise for places like water-treatment plants, oil-drilling operations, hospitals and ocean applications like underwater pipes that are sensitive to fouling," Tour said in a statement. (theengineer.co.uk)
  • Oral biofilms are the etiological factor for dental caries and periodontal disease. (ebscohost.com)
  • Prevention should focus on the removal of existing oral biofilms and inhibition of new biofilm formation. (ebscohost.com)
  • The eco-biology of biofilms, formerly called dental plaque in the case of oral biofilms, is yet to be fully explored. (sharjah.ac.ae)
  • Biodegradation of crude oil was estimated by gas chromatography, and biofilm formation near oil-water interface was quantified by confocal laser scanning microscopy. (mendeley.com)
  • Biofilm is a multidisciplinary, gold open access journal focused on hypothesis- or discovery-driven studies on microbial cells that grow in multicellular communities (including surface-attached biofilms and suspended aggregates) and demonstrate different gene expression, growth rate, behavior and appearance. (elsevier.com)
  • Animals were killed in a time series and the surface of the middle-ear mucosa was examined by scanning electron microscopy (SEM) for the presence of bacterial biofilms. (nih.gov)
  • This study aimed to collect and present information regarding the microbiological composition of equine wounds and to present evidence supporting the presence of bacterial biofilms within these wounds. (bl.uk)
  • This review addresses the current state of research into medical biofilm dispersal. (mdpi.com)
  • Lastly, we discuss some of the main hurdles to development of biofilm dispersal agents, and contemplate what needs to be done to overcome them. (mdpi.com)
  • In this Research Topic, we aim to highlight groundbreaking work in the development and/or application of quantitative analysis methods to bacterial biofilms, with a focus on those studies resulting in the discovery of new phenomena regulating biofilm initiation, development, function, or dispersal. (frontiersin.org)
  • This includes cell motility within biofilm and biofilms dispersal. (weizmann.ac.il)
  • 3. Biofilms can propagate through detachment of small or large clumps of cells, or by a type of 'seeding dispersal' that releases individual cells. (montana.edu)
  • Mucin coatings may help prevent biofilm formation on medical devices and could also find applications in personal hygiene: Incorporating them into products such as toothpaste or mouthwash may supplement the body's own defenses, especially in people whose natural mucus has been depleted, Ribbeck says. (medindia.net)
  • and (2) evaluate the efficacy of heat and chemical sanitizer treatments on inactivation of pathogens in biofilms formed on stainless steel. (uga.edu)
  • When LA (3%) and 2% LVA+0.5% SDS were applied to biofilms following treatment at 80ºC, all three pathogens were reduced to undetectable levels, i.e., samples were negative by enrichment. (uga.edu)
  • Springer Series on Biofilms presents carefully refereed volumes on selected topics on this field of research. (springer.com)
  • In fact, one of the first thorough studies of biofilms was carried out in an alpine stream. (medicalnewstoday.com)
  • V. cholerae biofilms consist of an extracellular matrix that is composed of Vibrio exopolysaccharides (VPS), lipids, nucleic acids and matrix proteins, including RbmA. (nature.com)
  • Biofilms, surface-associated microbial communities composed of aggregates of cells that are encased by an extracellular matrix, have a tremendous impact on industrial, clinical, and natural environments. (asm.org)
  • DNA has been described as a structural component of the extracellular matrix (ECM) in bacterial biofilms. (ebscohost.com)
  • At low cell density, biofilm genes, including Vibrio polysaccharide (VPS) biosynthesis genes and the major extracellular matrix genes RbmA, RbmC, and Bap1, are expressed. (genome.jp)
  • W. M. Dunne Jr., "Bacterial adhesion: seen any good biofilms lately? (hindawi.com)
  • As the biofilm progresses the adhesion is higher and chemical bonding is more hence lower the surface energy. (bio.net)
  • S. epidermidis biofilms were set up in vitro, erythromycin was acted as the positive control agent, XTT reduction assay was used to evaluate AG on the initial adhesion of S. epidermidis and bacterial metabolism within biofilm, microscope was applied to observe biofilm morphology, and Congo red assay was used to detect polysacchatide interc-ellular adhesion (PIA)formation when exposed to AG. (sigmaaldrich.com)
  • Biofilms are found naturally in many places, including teeth (plaque), medical devices such as intravenous catheters, prosthetic heart valves, and cardiac pacemakers, in sewage pipelines, ship hulls, and many other non-human environments. (google.com)
  • Biofilms stick to just about everything, from copper pipes to steel ship hulls to glass catheters. (innovations-report.com)
  • An artistic configuration of catheters in various stages of being clogged by biofilm. (infectioncontroltoday.com)
  • Studies that investigated anti-biofilm activities without describing the possible mechanisms were removed from the analysis. (mdpi.com)
  • Once the cells "sense" that a quorum has been reached, they begin to communicate, a process that in turn "throws the switch" for manufacturing virulence factors, such as biofilms. (scienceblog.com)
  • And in the mid-1980s, Joseph Lam of the University of Calgary in Alberta, using the transmission electron microscope, confirmed that biofilms are present in the lungs of cystic fibrosis patients. (sciencemag.org)
  • Pyocyanin has been used in the clinical identification of this strain for over a century, but several years ago the Newman group demonstrated that the molecule also supports biofilm growth, raising the possibility that its degradation might offer a new route to inhibit biofilm development. (caltech.edu)
  • One initial focus for research conducted at the Health Sciences Core Facility will be biofilms, which are implicated in 80 percent of infectious diseases. (eurekalert.org)
  • A revision of the new advances in biofilms research associated with infectious diseases, food industries, environmental and water biofilm as well as a vision of the new strategies to combat them will be compiled in this topic. (frontiersin.org)
  • Infective endocarditis is a typical biofilm-associated infectious disease frequently caused by commensal streptococci, but the contribution of host factors in biofilm formation is unclear. (ebscohost.com)
  • Battin TJ, Besemer K, Bengtsson MM, Romani AM, Packmann AI (2016) The ecology and biogeochemistry of stream biofilms. (springer.com)
  • 2016) Eradication of Enterococcus faecalis biofilms on human dentin. (weizmann.ac.il)
  • 2016) Methodologies to study Bacillus subtilis biofilms as models for characterizing small molecule biofilm inhibitors. (weizmann.ac.il)
  • 2016) Not so simple, not so subtle: The interspecies competition between Bacillus simplex and Bacillus subtilis and its impact on the evolution of biofilms. (weizmann.ac.il)
  • 2016) Spatio-temporal Assembly of Functional Mineral Scaffolds within Microbial Biofilms. (weizmann.ac.il)
  • International experts will write, or edit, volumes on specific aspects of biofilms, like research methods, or the roles of biofilms in diseases. (springer.com)
  • The journal looks forward to receiving manuscripts discussing translational biofilm research, i.e. manuscripts dealing with various applied aspects of biofilms (including but not limited to) standardization of biofilm approaches, vaccine development, identification of novel anti-biofilm compounds, study of biomaterials, bioengineering, etc). (elsevier.com)