Biodegradation of aromatic compounds by escherichia. Medical search. Frequent questions

Sequence alignments of the Thermus thermophilus and E. coli hpaB enzymes show structural similarity to each other and to the oxygenase components of other bacterial two-component monooxygenases for compounds such as phenol and chlorophenol. (wikipedia.org)
A pathway for stilbene biosynthesis was constructed in Escherichia coli with 4-coumaroyl CoA ligase 1 4CL1) from Arabidopsis thaliana and stilbene synthase (STS) cloned from Arachis hypogaea . (biomedcentral.com)
Phenylpropionic acids, such as 4-coumaric acid and caffeic acid, can be efficiently converted to stilbene compounds by recombinant E. coli cells expressing plant biosynthetic genes. (biomedcentral.com)
The concepts of his Pseudomonas putida study are interwoven with issues in Escherichia coli, Electron donor, Dioxygenase, Dehydrogenase and Naphthalene. (research.com)
His Pseudomonas putida research is multidisciplinary, incorporating elements of Nuclear chemistry, Escherichia coli, Toluene, Chromatography and Toluene dioxygenase. (research.com)
David T. Gibson has researched Stereochemistry in several fields, including Strain, Escherichia coli, Stereospecificity, Binding site and Reaction mechanism. (research.com)
His Escherichia coli research integrates issues from Regioselectivity, Microorganism, Pseudomonas putida, Metabolite and Toluene dioxygenase. (research.com)
5 In Escherichia coli , it has a strong affinity toward PBPs 1a, 1b, 2, 3, 4 and 5 with preferential binding to PBPs 2 and 3. (drugbank.com)
Two genes from Streptomyces albidoflavus , one exochitinase (905-bp) and an endochitinase (1100-bp) were functionally expressed in Escherichia coli in form of a fusion protein with a maltose binding protein (MBP). (springeropen.com)
To solve this, an Escherichia coli strain engineered to express alcohol dehydrogenase (adhA) and alkane hydroxylase (alkB) was designed. (biotreks.org)
Arita M. The metabolic world of Escherichia coli is not small. (crossref.org)
Metabolic engineering of a novel muconic acid biosynthesis pathway via 4-hydroxybenzoic acid in Escherichia coli. (biosynsis.com)
Engineering of more efficient PETases is required for industrial relevance, but progress is currently hampered by the dependency on intracellular expression in Escherichia coli . (biomedcentral.com)

Oil spills, the most visible impact, spread and contaminate vast areas by releasing toxic compounds like polycyclic aromatic hydrocarbons (PAHs) and heavy metals. (biotreks.org)

To cope with the wide variety of phenolic compounds found in nature, bacterial pathways for degradation of aromatic compounds generally begin by channeling these diverse substrates towards a few common intermediates, which are then further degraded. (wikipedia.org)
A number of bacteria that can degrade a variety of aromatic compounds have been identified and the pathways involved in the degradation have been extensively characterized [ 3 , 4 ]. (biomedcentral.com)
Based on the complexity of the degradation pathways, the phenomenon of biodegradation is categorized into two types: convergent and divergent modes of degradation (Fig. 1 ). (biomedcentral.com)
Microbial degradation of organic compounds. (research.com)
The analysis of both the metagenome of the consortium and the reconstructed metagenome-assembled genomes show that the most abundant bacterial genus in the consortium, Acidocella , possess many of the genes required for the degradation of diesel fuel aromatic hydrocarbons, which are often the most toxic component. (springeropen.com)

Bioremediation, which utilizes the microbial metabolic potential of the degrading microorganisms, has come up as an efficient and cost-effective means of large scale removal of these compounds in comparison to the physico-chemical means of bioremediation. (biomedcentral.com)
Oh M, Yamada T, Hattori M, Goto S, Kanehisa M. Systematic analysis of enzyme-catalyzed reaction patterns and prediction of microbial biodegradation pathways. (crossref.org)

Straight chain hydrocarbons were the least selected class of compounds with binding free energy ranging between −2.9 kcal/mol to −3.1 kcal/mol. (eeer.org)
The best binding free energies (−3.8 kcal/mol to −5.1 kcal/mol) were obtained with the poly-branched hydrocarbons and the cyclic compounds. (eeer.org)
The alkB gene breaks down alkanes, saturated hydrocarbons, by oxidizing the hydrocarbon into alkanols (in the case of aliphatic hydrocarbons) or phenols (in the case of aromatic molecules) and to be metabolized in further metabolic steps. (biotreks.org)

Optimization of precursor conversion and cyclization of the bulky ferulic acid precursor by host metabolic engineering and protein engineering may afford the synthesis of even more structurally diverse stilbene compounds. (biomedcentral.com)
In the convergent mode, structurally diverse aromatic compounds are converted to one of a few aromatic ring cleavage substrates such as catechol, gent sate, protocatechuate and their derivatives [ 5 ]. (biomedcentral.com)
Peripheral enzymes, particularly oxygenases and dehydrogenases, were found to transform structurally diverse substrates into one of these central intermediates by bringing about the hydroxylation of the aromatic nucleus (Fig. 2A ), and hence it is thought that bacteria have developed these enzymes to extend their substrate range [ 5 ]. (biomedcentral.com)

Analytical method was developed and validated for the determination of profenofos and λ-cyhalothrin in bacterial medium to monitor the intended biodegradation of both compounds. (omicsonline.org)
Surfactants are known to modulate the solubility of hydrophobic compounds and improve their transport through bacterial membranes by reducing surface and interfacial tensions thus favoring the desulfurization rate. (researchgate.net)

Pathways for catabolizing aromatic compounds generally begin by adding two hydroxyl groups to the benzene ring, most often on adjacent carbons. (wikipedia.org)

Due to the importance of the oxygenases in chemical synthesis of drug intermediates and oxidation of xenobiotic compounds, OxDBase database would be very useful tool in the field of synthetic chemistry as well as bioremediation. (biomedcentral.com)
The amounts of the poly-branched and cyclic compounds in the crude oil sample suggested that cysteine dioxygenase of B. subtilis would show about 28 % efficiency in the bioremediation of environments polluted by crude oil of this composition. (eeer.org)
Bioremediation functions basically on biodegradation, which involves the complete mineralization of organic contaminants into carbon dioxide, water, inorganic compounds, and cell protein [ 9 ]. (eeer.org)

The study was aimed to validate the claim of the efficient use of this organism in crude oil remediation and to determine the selectivity of the compounds in the crude by this bacterium enzyme. (eeer.org)
Recently, a PETase enzyme from the bacterium Ideonella sakaiensi s was shown to facilitate PET biodegradation, albeit at slow rate. (biomedcentral.com)

They play a key role in the metabolism of organic compounds by increasing their reactivity or water solubility or bringing about cleavage of the aromatic ring. (biomedcentral.com)
Organic compounds containing the carboxy group (-COOH). (lookformedical.com)
Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. (lookformedical.com)
Organic compounds containing a carbonyl group in the form -CHO. (lookformedical.com)

Biodegradation of the mixtures of 4-chlorophenol and phenol by Comamonas testosteroni CPW301. (sciepub.com)

The straight-chain hydrocarbon derivatives containing carbonyl and hydroxyl groups formed the middle class of compounds selected by the enzyme with binding free energy ranging between − 3.3 kcal/mol to −3.7 kcal/mol. (eeer.org)

instead it occasionally leads to the formation of metabolic products that are more toxic or persistent than the parent compound 4 . (nature.com)

Many of these compounds have been reported to be toxic to the living organisms [ 3 ]. (biomedcentral.com)

The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (lookformedical.com)

EFV has poor aqueous solubility and is classified under the Biopharmaceutical Classification System (BCS) as a class II compound with highly permeability, its aqueous solubility is less than 10 mg/ml and is defined as a practically insoluble compound with a consequent poor bioavailability of approximately 40%, and erratic dissolution behaviour. (ru.ac.za)
SEDDS formulations have been shown to improve the aqueous solubility and consequently the bioavailability of BCS II compounds such as EFV. (ru.ac.za)

A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds. (lookformedical.com)

The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. (lookformedical.com)

Without the seemingly invaluable compound comprised of hydrogen and oxygen, life on the earth would be non-existent. (scirp.org)
Compounds with a 5-membered ring of four carbons and an oxygen. (lookformedical.com)

Increased public awareness about the hazards and toxicity of these compounds has encouraged the development of technologies for their remediation. (biomedcentral.com)

The chemical properties and quantities of the xenobiotic compounds determine their toxicity and persistence in the environment. (biomedcentral.com)
The relationship between the chemical structure of a compound and its biological or pharmacological activity. (lookformedical.com)
Dorn E, Knackmuss H-J. Chemical structure and biodegradability of halogenated aromatic compounds. (crossref.org)

Reduction of nitroaromatic compounds mediated by Streptomyces sp. (readabstracts.com)

Phenylpropanoids are the precursors to a range of important plant metabolites such as the cell wall constituent lignin and the secondary metabolites belonging to the flavonoid/stilbene class of compounds. (biomedcentral.com)

Biodegradation is the most viable alternative for numerous health and environmental issues associated with non-biodegradable materials. (intechopen.com)

Growing concern about public health and the deteriorating quality of the environment has prompted the development of a range of new, rapid analytical devices for the detection of hazardous compounds in air, water and land. (biologydiscussion.com)

This highly inert polyester consists of repeating units of the aromatic building block terephthalate (TPA) linked to ethylene glycol (EG) [ 1 ]. (biomedcentral.com)

This chapter covers an overview of biodegradation, factors and challenges associated with biodegradation processes, involvement of nanotechnology and nanomaterials in biodegradation, and biodegradable nanomaterials. (intechopen.com)

The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound. (lookformedical.com)

A fungistatic compound that is widely used as a food preservative. (lookformedical.com)

His Anthracene, Decomposition, Biodegradation and Lignin study in the realm of Organic chemistry interacts with subjects such as Materials science. (research.com)

During the last few years an increasing number of health benefits have been associated with these compounds. (biomedcentral.com)

In the last few decades, extensive urbanization and rapid industrialization has resulted in the addition of a large number of xenobiotic compounds into the environment. (biomedcentral.com)

The production of cis-muconic acid is mainly based on aromatic compounds of petroleum origin. (biosynsis.com)

Anatomy2

Organisms40

Diseases1

Chemicals and Drugs130

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Phenomena and Processes49

Disciplines and Occupations4

Technology, Industry, Agriculture3

Information Science4

Health Care17

Coli13

Polycyclic aromatic hyd1

Degradation5

Microbial2

Hydrocarbons3

Structurally diverse3

Bacterial2

Pathways1

Bioremediation3

Bacterium2

Organic compounds4

Phenol1

Hydroxyl groups1

Metabolic1

Toxic1

Molecules1

Solubility2

Quantitative1

Parent compound1

Oxygen2

Remediation1

Chemical3

Reduction1

Class1

Numerous1

Water1

Highly1

Overview1

Form1

Food1

Study1

Health1

Addition1

Production1