• Iron oxide nanoparticles have high stability, good dispersion, simple preparation and good biocompatibility. (selfgrowth.com)
  • But compared with other nanomaterials, porous spherical CaCO 3 appeared to have good biocompatibility. (scirp.org)
  • Cytotoxicity assay indicated that nanoparticles have good biocompatibility and low toxicity. (nanobe.org)
  • Cytotoxicity analyses of the drug delivery system based on human gastric cancer SGC-7901 and rat pheochromocytoma PC12 cells show low cytotoxicity and good biocompatibility. (rsc.org)
  • Our results showed that none of the NP suspensions influenced the cell viability of the co-culture systems, suggesting their good biocompatibility on short-term exposure (24 hours) according to the cytotoxicity assays performed. (sciforum.net)
  • To sum up, Fe 3 O 4 NPs conjugated with acridine orange could be promising hybrid nanomaterial with good biocompatibility and special properties for future applications in biomedicine. (sciforum.net)
  • Owing to their super magnetic capabilities, biocompatibility, high specialized region, appropriate nano-sized particulates, and lower toxic effects, Fe2O3 nanomaterials are one of the most promising alternatives for magnetic-responsive devices according to the researchers [31, 103, 104] (Figure 3). (researchgate.net)
  • Nanomaterials (NMs) and nanoparticles (NPs) can be defined as the material with structures on the nanoscale dimension (between 1 and 100 nm) ( 1 ). (brieflands.com)
  • Among the different types of nanomaterials, magnetic gold nanoparticles (GNPs) have attracted much attention in the last decades. (sepmag.eu)
  • Dr. Chen completed her Ph.D. in Materials Science and Engineering at UCSD, where she discovered several ultrasound-based contrast agents, revealed cytotoxicity and adsorption properties of various nanomaterials, and created a theranostic nanoparticle that improved the treatment efficacy of stem cell therapy for heart diseases. (stanford.edu)
  • A versatile stable platform for multifunctional applications: synthesis of a nitroDOPA-PEO-alkyne scaffold for iron oxide nanoparticles. (musc.edu)
  • Scientists from SCAMT Institute have devised a way to produce nanoparticles of iron oxides (magnetite, hematite, maghemite) using water-alcohol synthesis, as well as modify their color, size, and functional properties. (wevolver.com)
  • One of the experiments resulted in the creation of nanoparticles, but for a period of time the researchers were unable to reproduce the synthesis. (wevolver.com)
  • A schematic of the solvothermal synthesis of iron oxides in a water-alcohol medium. (wevolver.com)
  • The green synthesis of metal and metal oxide nanoparticles (NPs), notably from plants, has attracted increasing attention in recent years. (springeropen.com)
  • Complicated synthesis routes, poor biocompatibility, low photo-stability, non-specific targeting, low cargo capacity, poor biodegradation and lower theranostics efficiency are the general major hurdles with these materials. (ntno.org)
  • A great effort has been recently devoted to the design and synthesis of new magnetic nanoparticles driven by the rapid development of the nanomedicine and nanobiotechnology [1]. (cyberleninka.ru)
  • Surface modification of superparamagnetic iron oxide nanoparticles (SPIONs) has been introduced with lauric acid and oleic acid via co-precipitation and thermal decomposition methods, respectively. (nature.com)
  • Superparamagnetic iron oxide nanoparticles (SPION) are extensively explored as T 2 contrast agent due to their excellent biocompatibility, easy biodegradability, potential nontoxicity and distinct magnetic properties [6-8]. (nanobe.org)
  • We report a new controlled-release targeted drug delivery system based on core-shell structured silica mesoporous microspheres capped with superparamagnetic iron oxide nanoparticles . (rsc.org)
  • The application of magnetism in medical science was first introduced in the 1950s for "magnetic hyperthermia therapy" (cancer cell death) leading to various MNPs' syntheses including Superparamagnetic iron oxide NPs (SPIONs). (sepmag.eu)
  • Effect of manganese substitution of ferrite nanoparticles on particle grain structure. (musc.edu)
  • Magnetic cobalt ferrite nanoparticles have been widely employed in various applications, such as medical applications due to their desirable characteristics. (ac.ir)
  • For this purpose, in the present study, it was tried to synthesize Ca 2+ and Gd 3+ doped cobalt ferrite nanoparticles by the sol-gel auto-combustion method and coat them with chitosan and polyethylene glycol polymers. (ac.ir)
  • X-ray diffraction (XRD) pattern along with the Rietveld refinement results confirmed the formation of pure cobalt ferrite nanoparticles with the average crystallite size of 27 nm. (ac.ir)
  • Observation of magnetic anomalies in one-step solvothermally synthesized nickel-cobalt ferrite nanoparticles. (ac.ir)
  • The unique features of SPIONs makes them multifunctional "theranostic systems" in various biomedical applications as diagnostics (e.g. immunoassays), movement (cell sorting), treatment (e.g. drug, protein and peptide delivery), and imaging (MRI contrast agents, magnetic nanoparticle imaging). (sepmag.eu)
  • There were synthesized two different types of iron oxide nanoparticles, maghemite (y-Fe2O3) and magnetite (Fe3O4). (cyberleninka.ru)
  • Among them, iron oxide nanoparticles, in particular magnetite Fe3O4 and maghemite y-Fe2O3, play a prominent role since iron is indispensable component of living organisms and has reduced toxicity [2]. (cyberleninka.ru)
  • G. F. Paciotti, D. G. I. Kingston and L. Tamarkin, "Colloidal Gold Nanoparticles: A Novel Nanoparticle Platform for Developing Multifunctional Tumor-Targeted Drug Delivery Vectors," Nanobiotechnology, Drug Development Research, Vol. 67, No. 1, 2006, pp. 47-54. (scirp.org)
  • Gold nanoparticles to enhance ophthalmic imaging. (stanford.edu)
  • Considering the excellent biocompatibility and high peroxidase-like activity of GQDs, we conducted our work using GQDs to improve the antibacterial activity of H 2 O 2 for the application of wound disinfection. (nanowerk.com)
  • Magnetic characterization of the synthesized nanoparticles indicated that the formation of the coating layer can affect the magnetic properties, so that the saturation magnetization (M s ) increased from 67.93 to 74.61 emu/g. (ac.ir)
  • Comanescu C. Magnetic Nanoparticles: Current Advances in Nanomedicine, Drug Delivery and MRI. (ac.ir)
  • Thus, despite the known cytotoxicity of cobalt and zinc ions, these results suggest that iron oxide nanoparticles can be doped to sufficiently tailor their magnetic properties without compromising cellular biocompatibility. (keele.ac.uk)
  • The focus of this review will be on the preparation and fabrication of T1 contrast agents that contain mainly paramagnetic manganese and iron ions, with special attention being paid to the growth mechanism. (materialstoday.com)
  • Magnetic CoFe2O4 nanoparticles doped with metal ions: A review. (ac.ir)
  • A specific hydrophilic coating based on both citrate ions and glucose molecules allows high biocompatibility of the nanomaterial in biological matrices and its use in vivo. (univr.it)
  • Moreover, the results of both thermogravimetry (TGA) test and Fourier transform infrared (FTIR) spectroscopy confirmed the formation of a coated layer of chitosan and polyethylene glycol polymers on the surface of nanoparticles. (ac.ir)
  • Finally, in order to constitute a chimeric organism based on chitin, in addition to graphene, and based on chitosan, a derivative of chitin, which have been used for many years to constitute polymers, nanogels and other hydrogels - in synergy with various forms of graphene or other metallic nanoparticles. (xochipelli.fr)
  • Abstract The preparation of novel porphyrin derivatives and their immobilization onto iron oxide nanoparticles to build up suitable nanotools for potential use in photodynamic therapy (PDT) has been explored. (docksci.com)
  • Relevant research results titled Hypoxia-Triggered Self-Assembly of Ultrasmall Iron Oxide Nanoparticles to Amplify the Imaging Signal of a Tumor are available on Journal of the American Chemical Society. (selfgrowth.com)
  • Hypoxia-Triggered Self-Assembly of Ultrasmall Iron Oxide Nanoparticles to Amplify the Imaging Signal of a Tumor. (selfgrowth.com)
  • Magnetic nanoparticles are actively being developed as contrast agents for diagnosis of tumor. (nanobe.org)
  • These magnetotactic bacteria have a high demand for iron, so once they reach the tumor, as Prof. Schürle-Finke told MNT , they "can metabolically influence cancer cells through starvation from this vital nutrient. (medicalnewstoday.com)
  • com tumor rec growing in a laboratory dish was destroyed after exposure to iron oxide-coated spirulina. (pariscrepe80903.com)
  • On the other hand, various small molecules have been coated on the surface of nanoparticles (organic, inorganic, and biological) which improve their biocompatibility, blood circulation time, specific biodistribution and tumor binding ability. (ntno.org)
  • Surface modification of QDs and MPs with silica has led to improved stability, lower toxicity, and higher biocompatibility, and protection of the QDs against corrosion by the biological buffer. (springer.com)
  • They reported that these magnetic biopolymer microspheres could exhibit significant effect on magnetic contrast capability suitable for MRI application, demonstrating that the microspheres could be suitable also as drug delivery vehicles, in addition, such PHBV/SPION microspheres exhibited biocompatibility towards human T-lymphoma suspension cells and adherent colon carcinoma HT-29 cells. (nature.com)
  • Bimetallic nanoparticles have demonstrated drawbacks in stabilized biocompatible formulations. (dntb.gov.ua)
  • A future extension of this work could be the design of biocompatible functional nanoparticles with high peroxidase-like activity to further improve the antibacterial activity of H 2 O 2 at low concentrations. (nanowerk.com)
  • Bifunctional magnetic-fluorescent composite nanoparticles (MPQDs) with Fe 3 O 4 MPs and Mn:ZnS/ZnS core-shell quantum dots (QDs) encapsulated in silica spheres were synthesized through reverse microemulsion method and characterized by X-ray powder diffraction, scanning electron microscopy, transmission electron microscopy, vibration sample magnetometer, and photoluminescence (PL) spectra. (springer.com)
  • The experimental conditions for the silica coating on the surface of Fe 3 O 4 nanoparticles, such as the ratio of water to surfactant ( R ), the amount of ammonia, and the amount of tetraethoxysilane, on the photoluminescence properties of MPQDs were studied. (springer.com)
  • Meanwhile, for in vivo applications, surface modification of iron oxide nanoparticles is introduced to increase the dispersity and blood circulation [14, 15]. (nanobe.org)
  • So, the COVID-19 possesses characteristics of ultra-small size, large specific surface, both hydrophilicity and lipophilicity, that just as all of the nanoparticles. (clinmedjournals.org)
  • Magnetic Nanoparticles (MNPs) are particles of nanosized range (10−9 nm)(usually ,100 nm in size) with unique properties of magnetic targeting, biocompatibility, surface modification characteristics and superparamagnetic properties. (sepmag.eu)
  • Nanogels have been explored as drug delivery systems due to their advantageous properties, such as biocompatibility, high stability, tunable particle size, drug loading capacity, and possible modification of the surface for active targeting by attaching ligands that recognize cognate receptors on the target cells or tissues. (sharif.edu)
  • Surface engineered nanoparticles (metallic and nonmetallic) have gained tremendous attention for precise imaging and therapeutics of cell/tumors at molecular and anatomic levels. (ntno.org)
  • Major hurdles experienced in the surface engineering routes (coating to nanovalves approach) and limitations of the designed theranostics such as poor biocompatibility, low photostability, non-specific targeting, low cargo capacity, poor biodegradation and lower theranostics efficiency are discussed in-depth. (ntno.org)
  • In this work, surface of the formed nanoparticles was opsonized with proteins available in the fetal bovine blood serum. (cyberleninka.ru)
  • Qu points out that the V 2 O 5 and magnetic iron oxide were considered to be toxic and inappropriate for the application in vivo unless via elaborate surface functionalization. (nanowerk.com)
  • Special interests include the ability for nanoparticle geometry and surface properties to interfere with the human immune system and bloodstream. (swansea.ac.uk)
  • To investigate and compare the biological effects of γ-Fe 2 O 3 nanoparticle (NP) and gadolinium dimeglumine (Gd-DTPA) with high and multiple doses on the kidney of healthy mice. (dovepress.com)
  • Magnetic nanoparticles of iron oxides (MPs) also show many advantages in biological applications. (springer.com)
  • The nanoparticle can be synthesized at room temperature in aqueous solution and in the absence of surfactants, has blood circulation and renal clearance profiles that prevent opsonization, and leads to better imaging performance than Dotarem (gadoterate meglumine), a clinically approved gadolinium-based MRI contrast agent. (nature.com)
  • Using AC susceptibility we studied doping induced changes in the magnetic response of the nanoparticles both as stable aqueous suspensions and when associated with cells. (keele.ac.uk)
  • Lipid-based nanoparticle (LBNP) systems represent one of the most promising colloidal carriers for bioactive organic molecules. (mdpi.com)
  • Some notable advantages of these carriers are biocompatibility, biodegradability, ease of preparation, and good loading and delivery efficacy ( 22 - 24 ). (brieflands.com)
  • We have shown in in vitro models that an increasing number of bacteria induce an upregulation of iron-scavenging receptors and death in cancer cells. (medicalnewstoday.com)
  • In vitro studies of heparin-coated magnetic nanoparticles for use in the treatment of neointimal hyperplasia. (musc.edu)
  • Martin gained his PhD at Edinburgh Napier University in 2009, in Nanoparticle In Vitro Toxicolog. (swansea.ac.uk)
  • Martin's research is focused on the nanoparticle-(mammalian)cell interaction, with a view to determining the mechanistic toxicological, immunological and genotoxic effects that nanoparticles, with varying physico-chemical characteristics, may cause at the cellular level by using advanced, next-level in vitro systems combined with state-of-the-art microscopy and bioanalytical approaches. (swansea.ac.uk)
  • Another clear ambition of Martin's research is to create, study and promote alternative in vitro models that mimic in vivo environments, in order to gain a mechanistic understanding of how nanoparticles may, potentially, adversely impact human health. (swansea.ac.uk)
  • Special focus is also given to creating disease-based in vitro models and the role nanoparticles play in disease onsert and/or exacerbation. (swansea.ac.uk)
  • 100 publications within the field of nanotoxicology and the nanoparticle-cell interaction in vitro . (swansea.ac.uk)
  • Fe 3 O 4 nanoparticles (NPs) can be conjugated with acridine orange to create a hybrid nanomaterial with unique properties, such as the magnetic characteristics of magnetite and the fluorescence of acridine orange, making them useful for a variety of applications, including cell imaging, drug delivery, and magnetic separation. (sciforum.net)
  • In this paper, an innovative, promising nanomaterial, M48 composed of iron oxide-based phases has been tested. (univr.it)
  • Recently there has been a wide concern on inorganic nanoparticles as drug delivery carriers. (scirp.org)
  • Researchers have already demonstrated that functional inorganic analogues, such as V 2 O 5 and magnetic iron oxide, can be used to assist H 2 O 2 for antibacterial application, i.e. killing bacteria and destroying bacterial biofilms. (nanowerk.com)
  • The overall goal of this procedure is to synthesize bacterial nano-cellulose, or BNC, and render it magnetic by impregnating in situ with iron oxide nano-particles. (jove.com)
  • The presence of functional groups of lauric acid, oleic acid and iron oxide in the PHBV microspheres was confirmed by Fourier Transform Infrared spectroscopy (FTIR). (nature.com)
  • One of the main advantages of working with nanoparticles is the manipulation of their properties by controlling the material, size and shape of the nanocore, and the chemical functionalization with specific ligands, which provides multifunctionality to the nanosystem [6]. (docksci.com)
  • Additional emphasis is also put on their progressive development in an aim to overcome the drawbacks of classical iron oxide nanoparticle-based T2 and Gd3+-based T1 contrast agents. (materialstoday.com)
  • The effect of zinc doping on the magnetic properties of Fe 3 O 4 nanoparticles was studied. (nanobe.org)
  • Since iron ion contains five unpaired electrons, the iron oxide nanoparticles can also be used as a T 1 contrast agent and magnetic properties are closely related to their size [9-12]. (nanobe.org)
  • Nanoparticles (NPs) are the building blocks responsible for nanotechnology's applicative properties. (springeropen.com)
  • Although generally magnetic nanoparticles are appropriate for such employments, their applications are restricted due to their toxic properties. (ac.ir)
  • This is accomplished by the preparation of dextran-coated magnetic nanoparticles using a facile rapid co-precipitation method. (springeropen.com)
  • These iron oxide nanorods have strong light resistance, and are non-toxic, tasteless, insoluble in alkali and slightly soluble in acid, and can be widely used in coatings, plastics, paints and pharmaceutical fields. (selfgrowth.com)
  • In advanced cancer therapy, the combinational therapeutic effect of photothermal therapy (PTT) using near-infrared (NIR) light-responsive nanoparticles (NPs) and anti-cancer drug delivery-mediated chemotherapy has been widely applied. (oncotarget.com)
  • Recently, a research team has made progress in the use of hypoxia-assembled ultra small iron oxide nanoparticles to amplify the fluorescence and magnetic resonance imaging signals of tumors. (selfgrowth.com)
  • In this study, the researchers developed a novel hypoxia imaging probe, consisting of a hypoxia-triggered self-assembling ultrasmall iron oxide (UIO) nanoparticle and assembly-responding fluorescence dyes (NBD), to provide dual-mode imaging in vivo. (selfgrowth.com)
  • The nanoparticle's biocompatibility and imaging performance may prove advantageous in a broad range of preclinical and clinical applications of MRI. (nature.com)
  • Here, a review on the evolution of nanoparticles and their choice for diagnostics and therapeutics applications has been discussed. (ntno.org)
  • In this article, based on analysis of chemical composition and morphology structure of the New Coronavirus Disease-19 (COVID-19), that the COVID-19 belongs a kind protein nanoparticle virus with spherical complex structure has been explained. (clinmedjournals.org)
  • Bimetallic zinc oxide/iron oxide (magnetic form) nanoparticles (ZnO@Fe3O4NPs) were formulated using casein and starch as capping agents and stabilizers. (dntb.gov.ua)
  • To achieve this purpose, a zinc porphyrin derivative, ZnPR-COOH, has been synthesized, characterized at the molecular level and immobilized onto previously synthesized iron oxide nanoparticles covered with oleylamine. (docksci.com)