Biochemical mechanisms. Medical search. Frequent questions

Plant hormones such as cytokinins (CK) are signaling molecules controlling gene expression and the activity of various biochemical pathways. (rutgers.edu)
It is required for normal cell processing such as cell division and apoptosis participating in multiple biochemical pathways such as transcription and cell division. (scirp.org)
These discrete catabolic pathways were verified by biochemical and microscopic techniques. (cdc.gov)
In conclusion, these two types of nanomaterial s with unique geometries differ significantly in their uptake mechanisms and induced lysosomal and autophagic catabolic pathways in human primary macrophages. (cdc.gov)
Many mechanisms of protein function contribute to amyloidogenesis, including "nonphysiologic proteolysis, defective or absent physiologic proteolysis, mutations involving changes in thermodynamic or kinetic properties, and pathways that are yet to be defined. (medscape.com)
The mechanisms of action of ototoxic substances may involve the entire organ, specific cells within the organ, components of specific cells, or individual biochemical pathways. (cdc.gov)

Proving and understanding these biochemical reactions in vivo will fill a substantial gap in our knowledge of cellular biochemistry in diabetics. (findaphd.com)
CMPS offers undergraduate and Master's level courses in biochemistry and biochemical techniques, as well as various courses in biophysical chemistry, NMR spectroscopy, and general physical chemistry. (lu.se)

Conclusion: Our results establish indicate ed that leaf osmoregulation, K + retention, Na + exclusion, and ion homeostasis are the main physiological mechanisms conferring salinity tolerance of these cultivars, rather than the regulations of leaf antioxidative ability.As an index of salinity tolerance, K + /Na + ratio in leaves or roots can be used for the selective breeding of highland quinoa cultivars. (researchsquare.com)
In order to tolerate soil salinization conditions, besides anatomical and morphological plasticity, plants have evolved multiple physiological mechanisms, e.g., osmotic adjustment, increased antioxidant response, accumulation or exclusion of ions, and ion homeostasis to maintain plant growth. (researchsquare.com)
An introduction to the biochemical and physiological mechanisms of living organisms. (sfu.ca)

The main goals of the research described in this thesis were to evaluate mechanisms responsible for drought tolerance in turfgrasses by evaluating whole-plant, cellular, proteomic, metabolomic, genetic, and genomic regions associated with drought defense responses. (rutgers.edu)
The purpose of this study was to identify endogenous factors that predispose vulnerable neurons to OS by employing genomic and biochemical approaches. (biomedcentral.com)
The various biochemical, physiological, and genomic factors that can influence BBB permeability in ALS and other neurodegenerative diseases are also discussed, in addition to novel therapeutic strategies centred upon the BBB. (hindawi.com)

In this study, proteomics and metabonomics techniques were used to analyze the tissue and plasma of DOX-induced heart failure (HF) in rats and to clarify the molecular mechanism of the harmful effects of DOX on cardiac metabolism and function in rats from a new point of view. (frontiersin.org)

Since OS-sensitive neurons might be the ones that degenerate early during the aging process or in certain neurodegenerative diseases [ 1 ], study of the molecular mechanisms of SNV to OS may offer insights into both aging-associated and disease-initiated neurodegeneration, as well as provide leads to the protection of vulnerable neurons. (biomedcentral.com)

The attenuation of metal/peroxide oxidative chemistry, as well as lipid peroxidation, appears to be the major chemical mechanisms by which NO may limit oxidative injury to mammalian cells. (researchgate.net)
In addition to these chemical and biochemical properties, NO can modulate cellular and physiological processes to limit oxidative injury, limiting processes such as leukocyte adhesion. (researchgate.net)

Considerable emphasis on modern theoretical interpretation of structure and of reaction mechanisms. (beloit.edu)

This article considers the biochemical adaptation process development analysis of different organisms to various factors and the universal character of adaptation mechanisms. (researchbib.com)
Used for mechanisms of heredity and the genetics of organisms, for the genetic basis of normal and pathologic states, and for the genetic aspects of endogenous chemicals. (bvsalud.org)

EVALUATION FOR ACCEPTABLE INTAKE BIOLOGICAL DATA Biochemical aspects Absorption, distribution and excretion The absorption, distribution, and excretion of paraquat in experimental animals have been reviewed by WHO (1984). (inchem.org)

Mechanisms of resistance to indoxacarb in Helicoverpa armigera (Lepidoptera: Noctuidae): the synergistic effects of PBO, DEF and DEM and the activities of detoxification enzymes [J]. , 2017, 60(8): 912-919. (insect.org.cn)

The results are interpreted in the light of the above-mentioned electrophysiological evidence, in an attempt to evaluate the scope and mechanisms of α-adrenoceptor-mediated control of stimulus-secretion coupling in the average individual varicosity of the sympathetic nerves of vas deferens. (portlandpress.com)
Release of Vasopressin within the Rat Paraventricular Nucleus in Response to Emotional Stress: A Novel Mechanism of Regulating Adrenocorticotropic Hormone Secretion? (jneurosci.org)

This article reviews the current knowledge and experimental research about the mechanisms by which fatty acids and their derivatives control specific gene expression involved during carcinogenesis. (springer.com)
Knowledge of the mechanisms by which fatty acids control specific gene expression may identify important risk factors for cancer and provide insight into the development of new therapeutic strategies for a better management of whole body lipid metabolism. (springer.com)

To investigate the salinitytolerance mechanisms, five contrasting quinoa cultivars belonging to highland ecotype were compared for their seed germination (under 0, 100 and 400 mM NaCl) and seedling's responses under five salinity levels (0, 100, 200, 300 and 400 mM NaCl). (researchsquare.com)
Further studies are needed to dissect the factors associated with soil age and its influence on soil biochemical responses to FT events. (springer.com)

We want to understand the molecular mechanisms of biological processes by exploring the structure, dynamics, interactions and function of proteins. (lu.se)

Subsequent targeted biochemical analyses confirmed the lower energy levels (in the form of ATP) in primary CbG neurons compared with cortical neurons. (biomedcentral.com)
We use a combination of classical, modern and chemical genetic screens with biochemical and high-resolution imaging analyses. (umassmed.edu)

These adaptive molecular and structural mechanisms increase respiration to maintain basic processes specific to cell types and tissues. (nature.com)

Release and transport mechanisms from source to air, groundwater, soil. (up.ac.za)

Considered, by many authors, as one of the most usual sequelae of orthodontic treatment, root resorption was the focus of this review of literature, which aimed to reexamine and clarify the biochemical mechanisms of resorption, as well as influent factors, either individual or regarding the very orthodontic treatment. (bvsalud.org)

Work in our department has identified new mechanisms of transgenerational inheritance where information is passed through the biologically paternal lineage to embryos developing in the uterus. (umassmed.edu)

Antimicrobial resistance occurs through different mechanisms, which include spontaneous (natural) genetic mutations and horizontal transfer of resistant genes through deoxyribonucleic acid (DNA). (who.int)
Biochemical signs and severity of symptoms of primary hyperparathyroidism (pHPT) differ among patients, and little is known of any coupling of clinical characteristics of nonfamilial pHPT to genetic abnormalities in the parathyroid tumors. (lu.se)
It includes biochemical and molecular influence on genetic material. (bvsalud.org)

The biochemical marker of the disease is currently considered to be the accumulation of an abnormal isoform (PrPres) of the normal cellular prion protein (PrPc). (cdc.gov)
Here we provide biochemical and cellular evidence that artemisinins are potent inhibitors of Plasmodium falciparum phosphatidylinositol-3-kinase (PfPI3K), revealing an unexpected mechanism of action. (nature.com)

In general, chemical reactions occur faster in the presence of a catalyst because the catalyst provides an alternative reaction mechanism (reaction pathway) having a lower activation energy than the non-catalyzed mechanism. (wikipedia.org)

PTE treatment maintained calcium and phosphorus homeostasis and improved other blood biochemical parameters to various degrees. (researchgate.net)
Physical exercise is a great ally, having beneficial effects on patients with CKD, and with that, this study was done to analyze the effects of aerobic exercise on the biochemical parameters of patients with CKD during hemodialysis. (bvsalud.org)

Most importantly, nutritional care should target the underlying mechanisms of reduced food intake/impaired anabolic response, and aim at minimising the impact of catabolic crisis, to maximise the recovery phase. (cambridge.org)

Mechanisms of insecticide resistance were studied in a field-selected resistant population (HJ-R) of Helicoverpa arrnigera. (insect.org.cn)
The monooxygenase seems to be the most important mechanism of carbamate resistance in HJ-R population. (insect.org.cn)

Fig. 4: Post-translational mechanisms governing respiratory control and the role of mitochondrial membrane dynamics. (nature.com)

[ 7 ] Thus, diverse biochemical mechanisms are responsible for altered protein function. (medscape.com)

The main groups include sodium channel blockers, calcium current inhibitors, gamma-aminobutyric acid (GABA) enhancers, glutamate blockers, carbonic anhydrase inhibitors, hormones, and drugs with unknown mechanisms of action (see the image below). (medscape.com)
The mechanism by which decreased activity of the SERCA2 calcium pump leads to these changes is still under investigation. (medscape.com)

Insufficient information on universal mechanisms implemented during different ways of cell adaptation is a current issue. (researchbib.com)

It is important to understand the mechanisms of action and the pharmacokinetics of antiepileptic drugs (AEDs) so that these agents can be used effectively in clinical practice, especially in multidrug regimens (see the image below). (medscape.com)
Clinical and biochemical characteristics of HPT were apparently unrelated to the presence or absence of LOH and the MEN1 gene mutations. (lu.se)

also, it appears to be regulated by the same modulators, such as prostaglandins, interleukins and tumor necrosis factor-a, showing a close relationship to inflammation mechanisms. (bvsalud.org)
Here, we hypothesised that prebiotic modulation of gut microbiota lowers intestinal permeability, by a mechanism involving glucagon-like peptide-2 (GLP-2) thereby improving inflammation and metabolic disorders during obesity and diabetes. (bmj.com)

The mechanisms by which specific ATP2A2 mutations impact the function of the ATP2A2 protein have been investigated using an in vitro model. (medscape.com)
Because the disease-causing mutations in ATP2A2 affect functional domains of the gene, the mechanism of autosomal dominant transmission is believed to be haploinsufficiency, in which a single wild-type functioning ATP2A2 is insufficient to prevent disease. (medscape.com)
Many of the detected mutations would most likely result in a nonfunctional menin protein, consistent with a tumor suppressor mechanism. (lu.se)

Antiepileptic drugs can be grouped according to their major mechanism of action. (medscape.com)
Some antiepileptic drugs work by acting on combination of channels or through some unknown mechanism of action. (medscape.com)

The study of biochemical adaptations has academic and applied significance and allows understanding the delicate nature of survival cell mechanisms. (researchbib.com)

Here, we summarize current progress on understanding the mechanisms and bioactive components of Pu-erh's weight-cutting effects as well as highlighting current weaknesses in the field in order to suggest possible solutions for future research on Pu-erh tea. (researchgate.net)

Western blot methods for characterization of the protease-resistant prion protein showed that all these isolates shared a unique biochemical signature: 5 groups of bands, including a characteristic band of apparent low molecular weight (11 kDa). (cdc.gov)

A new study reveals a possible biochemical mechanism which underlies the formation of long-term memories. (neurosciencenews.com)

Several theories have been proposed to explain the exact mechanism through which these agents cause neurotoxicity. (ajnr.org)

In this study we investigated a panel of 54 French atypical isolates from sheep (n = 51) and goats (n = 3) and compared their PrP genotypes and advanced PrPres biochemical signatures (WB electrophoretic mobility, epitope mapping, and PrPres deglycosylation pattern) with those of Nor98 cases. (cdc.gov)

This analysis discriminates between different biological mechanisms to achieve a transient signal from a sustained TGF-b input, where one mechanism is to use a negative feedback to turn the signal off. (lu.se)
Using microsatellite analysis for loss of heterozygosity (LOH) at 11q13 and DNA sequencing of coding exons, the MEN1 gene was studied in 49 parathyroid lesions of patients with divergent symptoms, operative findings, histopathological diagnosis, and biochemical signs of nonfamilial pHPT. (lu.se)

However, additional mechanisms exist for the antiproliferative effect of SNP. (scirp.org)

The AEDs can be grouped according to their main mechanism of action, although many of them have several actions and others have unknown mechanisms of action. (medscape.com)

The Brown Ring disease in clams, a double-edged defense mechanism for shell disease recovery! (canal-u.tv)
Dr Christine Paillard - The Brown Ring disease in clams, a double-edged defense mechanism for shell disease recovery! (canal-u.tv)
More efficient mechanisms in the treatment of this disease should be investigated. (bvsalud.org)

Body weight, blood biochemical indicators, relative organ coefficients, femoral bone mineral density (BMD), bone biomechanical properties, and bone microarchitecture were examined and analyzed. (researchgate.net)

Anatomy22

Organisms14

Diseases4

Chemicals and Drugs93

Analytical, Diagnostic and Therapeutic Techniques and Equipment40

Phenomena and Processes79

Disciplines and Occupations5

Information Science6

Health Care2

Pathways6

Biochemistry2

Physiological mechanisms3

Genomic3

Molecular mechanism1

Neurodegenerative diseases1

Oxidative2

Theoretical1

Organisms2

Absorption1

Enzymes1

Secretion2

Gene expression2

Responses2

Proteins1

Analyses2

PROCESSES1

Soil1

Clarify1

Biologically1

Genetic3

Cellular2

Reactions1

Parameters2

Intake1

Resistance2

Dynamics1

Protein function1

Calcium2

Adaptation1

Clinical2

Inflammation2

Mutations3

Drugs2

Cell1

Research1

Resistant1

FORMATION1

Theories1

Study1

Analysis2

Effect1

Main1

Disease3

Properties1