MoleculesSubstratesPlant-derivedAnaloguesMimicsOrganicExtractAromaticInhibitorsSynthesisTargetsProteinsFoodsPowderSubstancesResearchNaturalHighlyActiveComplexProductsIncludeApproachXenobiotic compoundsAssayPhenolicAnti-inflammatoryPrecursorsPharmacologicalPotentCytotoxicityReceptorHerbalStudyValuableActivityEffectPresentCapableDevelopmentHealth
Molecules2
- 3. Research on bioactive molecules: For the study of certain bioactive molecules, such as proteins, enzymes, etc., the chelation effect of EDTA may affect their activity or stability. (hbdsbio.com)
- Our ready-to-use ChemScene compound libraries consist of over 4000 small molecules with validated biological and pharmacological activities. (chemscene.com)
Substrates2
- Display our full list of chromogenic substrates . (megazyme.com)
- New chromogenic substrates for the assay of alpha-amylase and (1→4)-β-D-glucanase. (megazyme.com)
Plant-derived2
- Previous studies showed that different plant-derived flavonoid compounds could stimulate osteoblasts function, and inhibit osteoclasts functions either alone or in combination. (biomedcentral.com)
- The use of plant-derived bioactive compounds has gained significant popularity due to their potential benefits such as weight loss, stress relief, and revitalization. (laboratoire-cellmade.fr)
Analogues2
- Moreover, a selective analytical method based on high performance liquid chromatography with fluorescence detection (HPLC-FLD) for the simultaneous identification and quantification of thirteen compounds including bisphenol analogues (BPA, BPB, BPC, BPE, BPF, BPG) and BADGEs (BADGE, BADGE. (academic-accelerator.com)
- The present invention relates generally to the synthesis of fluorescent compounds that are analogues of cyanine dyes. (justia.com)
Mimics2
- H-D-Phe-Pip- Arg -pNA dihydrochloride, a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fib. (targetmol.com)
- Screening of a collection of 450 compounds as inhibitors revealed a structure-activity relationship that mimics in part that of mammalian DPP9. (inra.fr)
Organic3
- Indole is an aromatic, heterocyclic, organic compound with the formula C8H7N. (wikipedia.org)
- OBJECTIVES To apply a combined metabolomic fingerprinting approach by nuclear magnetic resonance (NMR) and gas chromatography-mass spectrometry (GC-MS) to common dandelion, corn poppy and stinging nettles to obtain simultaneous identification and quantitation of the major classes of organic compounds. (academic-accelerator.com)
- Current material science, pharmaceutical, and organic chemistry compound synthesis reaction pathway determination has been implemented with various computational chemistry methods. (asdrp.org)
Extract4
- Bioassay guided fractionation on each extract establishes for exploring S. jamaicensis leaves active compounds. (bvsalud.org)
- The extract of fresh and HPD dried drumstick powder contained 50 major bioactive compounds such as 2,6-Dihydroxybenzoic acid 3TMS derivative, Butanal 2-ethyl-3-methyl-, etc, these bioactive compounds act as various nutraceuticals and therapeutic values. (arccjournals.com)
- The company also notes that the extract is highly bioactive with a 20 to1 concentration ratio, meaning 20 kg of Chaga produces 1 kg of extract. (nutritioninsight.com)
- To ensure their optimal effectiveness, it is necessary to extract and concentrate bioactive compounds using advanced technological processes that allow them to reach the desired plasma concentrations. (laboratoire-cellmade.fr)
Aromatic1
- Helical inclusion complexes of amylose with aromatic compounds: crystallographic evidence for new V-type allomorphs. (toulouse-biotechnology-institute.fr)
Inhibitors1
- Berries are rich in bioactive compounds, including antioxidants and especially polyphenols, known inhibitors of starch metabolism enzymes. (bvsalud.org)
Synthesis1
- She is currently focusing on small molecule synthesis but is also venturing into natural products and metal-based bioactive compounds. (monash.edu)
Targets1
- MCE owns a unique collection of 17212 compounds with confirmed biological activities and clear targets. (chemscene.com)
Proteins1
- These compounds generally penetrate cell membranes, act on specific target proteins in cells, regulate intracellular signaling pathways, and cause some changes in cell phenotype. (chemscene.com)
Foods1
- Evaluation of a chromogenic medium for total coliforms andEscherichia coli determination in ready-to-eat foods. (potravinarstvo.com)
Powder1
- HPD dried drumstick powder at 55°C was found maximum drying characteristics and higher retention of bioactive compounds with special reference to high powder recovery (97.22%), excellent flowability and better functional characteristics. (arccjournals.com)
Substances2
- Ligand fishing is a suitable approach for the highly selective screening of bioactive substances in complex mixtures. (bvsalud.org)
- Bioactive compounds are a general term for a class of substances that can cause certain biological effects in the body, which are the main source of small molecule drugs. (chemscene.com)
Research2
- 2. Specific anticoagulants: For drug analysis or bioactive molecule research, specific anticoagulants in the experiment can be selected to ensure the stability and accuracy of the sample. (hbdsbio.com)
- Compound libraries are useful professional tools for drug discovery and new indication research. (chemscene.com)
Natural1
- Therefore, these natural compounds may be of interest to be used to supplement oral healthcare products. (biomedcentral.com)
Highly2
- Considering the highly concentrated nature of these compounds, it is crucial to assess their efficacy, quality, and potential toxicity in order to safeguard human health. (laboratoire-cellmade.fr)
- Cyanine dyes that are highly charged, such as those including multiple sulfonate, alkylsulfonate, carboxylate and/or alkylcarboxylate moieties are examples of cyanine dyes of use in the compounds of the invention. (justia.com)
Active1
- Dipivefrin hydrochloride (Dipivefrine hydrochloride) is an antiglaucoma proagent that is hydrolyzed to the active compound, epinephrine, by esterases in the cornea. (medchemexpress.com)
Complex1
- Expertly extracted in alignment with the wisdom of traditional Siberian herbalists and then freeze dried to capture and secure the valuable chromogenic complex compounds that chaga's powerful immune boosting & numerous adaptogenic properties are revered for. (primalalchemy.co.uk)
Products1
- designed an HPD dryer, which resulted in the retention of bioactive compounds in dried products. (arccjournals.com)
Include1
- Other indolic compounds include the plant hormone auxin (indolyl-3-acetic acid, IAA), tryptophol, the anti-inflammatory drug indomethacin, and the betablocker pindolol. (wikipedia.org)
Approach1
- This integrated approach, supported by a robust dataset, expedites the discovery and development of safe and effective bioactive compounds. (laboratoire-cellmade.fr)
Xenobiotic compounds1
- it plays a key role in the maintenance of GSH homeostasis, detoxification of xenobiotic compounds, and metabolism of endogenous biomolecules. (hindawi.com)
Assay2
- 16. A competitive chromogenic assay to study the functional interaction of urokinase-type plasminogen activator with its receptor. (nih.gov)
- tomentosum exhibited PAI-1 inhibitory activity, and identified Toddalolactone as the main active component that inhibited the activity of recombinant human PAI-1 with IC50 value of 37.31 ± 3.23 μM, as determined by chromogenic assay, and the effect was further confirmed by clot lysis assay. (chemfaces.com)
Phenolic2
- Among them, phenolic acids and flavonoids are the main compound classes that show pharmacological activities in Toxicodendron plants both in vitro and in vivo. (bvsalud.org)
- Cannabis leaves contain a diverse range of antioxidants, including cannabinoids, flavonoids, and phenolic compounds, which offer significant health benefits. (mdpi.com)
Anti-inflammatory3
- Other indolic compounds include the plant hormone auxin (indolyl-3-acetic acid, IAA), tryptophol, the anti-inflammatory drug indomethacin, and the betablocker pindolol. (wikipedia.org)
- Background: The anti-inflammatory activity of magnolol and related compounds is currently a focus of interest. (iiarjournals.org)
- Native Brazilian flora is an important source of bioactive natural products, including antimicrobial and anti-inflammatory substances [ 43 ]. (biomedcentral.com)
Precursors2
- Mechanistic Studies of the TRIP Catalyzed Allylation with Organozinc Reagents 3,3-Bis(2,4,6-triisopropylphenyl)-1,1-binaphthyl-2,2-diyl hydrogenphosphate (TRIP) catalyzes the uneven allylation of aldehydes with organozinc compounds leading to extraordinarily worthwhile structural motifs, like precursors to lignan pure merchandise. (tissue-cell-culture.com)
- Substituted indoles are structural elements of (and for some compounds, the synthetic precursors for) the tryptophan-derived tryptamine alkaloids, which includes the neurotransmitter serotonin and the hormone melatonin, as well as the naturally occurring psychedelic drugs dimethyltryptamine and psilocybin. (wikipedia.org)
Pharmacological1
- Biomolecules & Therapeutics (Biomolecules & Therapeutics) (Print ISSN 1976-9148, Online ISSN 2005-4483) is an international, peer-reviewed, open access journal that covers pharmacological and toxicological fields related to bioactive molecules and therapeutics. (koreascience.kr)
Potent2
- The screening of medicinal plants used locally for the treatment of infectious diseases, can provide a reliable option in the discovery of potent therapeutic compounds. (biomedcentral.com)
- The prodrugs, except compound 5, exhibited very potent activity similar to that of araC ( $ED_{50}$ about $0.12{\mu}g/mι$ ) when evaluated against another human DNA virus, cytomegarovirus. (koreascience.kr)
Cytotoxicity1
- Among the compounds, emodin addressed to the ethanol-induced cytotoxicity more effectively compared to the chrysophanol. (hindawi.com)
Receptor1
- PAH compounds are not estrogenic, and indeed, stomach and small intestine digestions of 62.5 nmol naphthalene, phenanthrene, pyrene, and benzo( a )pyrene showed no estrogenic effects in the human estrogen receptor bioassay. (nih.gov)
Herbal1
- 5. Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase. (nih.gov)
Study2
- In the present study, the inhibitory effects of these compounds on cyclooxygenase (COX-2) expression and nuclear factor-kappa B (NF-κB) activation were investigated in RAW264.7 macrophage-like cells stimulated with the fimbriae of Porphyromonas gingivalis, an oral anaerobe. (iiarjournals.org)
- A study in Clinical Cancer Research has shown that the new drug NUC-7738, developed by NuCana, has a up to 40 times greater potency for killing cancer cells than its parent compound, with limited toxic side effects. (ox.ac.uk)
Valuable1
- Expertly extracted in alignment with the wisdom of traditional Siberian herbalists and then freeze dried to capture and secure the valuable chromogenic complex compounds that chaga's powerful immune boosting & numerous adaptogenic properties are revered for. (primalalchemy.co.uk)
Activity2
- Ethanol-induced HepG2/CYP2E1 cells were treated with the compounds at various concentrations, and the results showed that there was a dose-dependent decrease of gamma-glutamyl transpeptidase (GGT) activity and increase of glutathione (GSH) in the culture media with an increase in cell viability. (hindawi.com)
- Screening of a collection of 450 compounds as inhibitors revealed a structure-activity relationship that mimics in part that of mammalian DPP9. (inra.fr)
Effect1
- The regulatory effect of these compounds on the expression of COX-2 mRNA, stimulated by exposure to the fimbriae was investigated by real-time polymerase chain reaction (PCR). (iiarjournals.org)
Present1
- The Bestmann-Ohira Reagent and Related Diazo Compounds for the Synthesis of Azaheterocycles Azaheterocycles are one of the crucial prevalent programs of compounds present in fairly a number of bioactive compounds, pure merchandise, and agrochemicals, and undoubtedly, new methods to entry them are on a regular basis in extreme demand. (tissue-cell-culture.com)
Capable1
- These compounds may be capable of preventing chronic inflammatory diseases induced by oral bacteria. (iiarjournals.org)
Development1
- Cordyceps sinensis has had potential applications in cancer treatment for hundreds of years, but the limitations of its bioactive compound Cordycepin has prevented its development into approved chemotherapy drugs. (ox.ac.uk)
Health1
- Hence, if microbial PAH bio-transformation in the human colon is possible, the susceptibility of the colon epithelium to bioactive PAH metabolites may increase the health risks that are associated with non-absorbed PAHs that reach the colon. (nih.gov)