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Anatomy19

Cell Line CHO Cells Periaqueductal Gray Brain Spinal Cord Cells, Cultured Cell Membrane Nociceptors HeLa Cells Neurons COS Cells Vas Deferens Ileum Tumor Cells, Cultured Locus Coeruleus Nucleus Accumbens Cell Nucleus Cell Line, Tumor Medulla Oblongata

Organisms15

Rats, Sprague-Dawley Cricetinae Guinea Pigs Cricetulus Escherichia coli Rats, Wistar Cattle Salvia Mice, Inbred ICR Mice, Inbred C57BL Rabbits Mice, Knockout Saccharomyces cerevisiae Cercopithecus aethiops Rats, Inbred Strains

Diseases18

Opioid-Related Disorders Pain Substance Withdrawal Syndrome Chronic Pain Morphine Dependence Heroin Dependence Pain, Intractable Drug Overdose Hyperalgesia Pain, Postoperative Substance-Related Disorders Chronic Disease Acute Pain Cocaine-Related Disorders Nociceptive Pain Neonatal Abstinence Syndrome Pruritus Disease Models, Animal

Chemicals and Drugs107

Receptors, Opioid, mu Receptors, Opioid Analgesics, Opioid Receptors, Opioid, delta Receptors, Opioid, kappa Opioid Peptides Narcotic Antagonists Naloxone Naltrexone Enkephalins Enkephalin, Ala(2)-MePhe(4)-Gly(5)-Morphine Narcotics Enkephalin, D-Penicillamine (2,5)-Endorphins Dynorphins Buprenorphine Enkephalin, Leucine Enkephalin, Leucine-2-Alanine Diprenorphine beta-Endorphin Benzeneacetamides Analgesics Morphinans Fentanyl Methadone Hydromorphone Benzomorphans Pyrrolidines Heroin Ligands Levorphanol Oligopeptides Butorphanol Prescription Drugs Diterpenes, Clerodane DNA-Binding Proteins Oxymorphone Ethylketocyclazocine Morphine Derivatives Recombinant Proteins Benzylidene Compounds Cyclazocine Analgesics, Non-Narcotic Recombinant Fusion Proteins Transcription Factors Carrier Proteins D-Ala(2),MePhe(4),Met(0)-ol-enkephalin Guanosine 5'-O-(3-Thiotriphosphate)Alfentanil Nalbuphine Hydrocodone Tramadol DNA Sufentanil Loperamide Opiate Alkaloids Piperidines Peptide Fragments Azocines RNA, Messenger Methadyl Acetate Codeine Nuclear Proteins Pentazocine Peptides Somatostatin Meperidine Dihydromorphine Meptazinol Bacterial Proteins Membrane Proteins RNA-Binding Proteins Spiro Compounds DNA, Complementary Repressor Proteins Antibodies, Monoclonal Receptors, Cell Surface Protein Precursors DNA Primers Macromolecular Substances Opium Cyclic AMP Tetrahydroisoquinolines Adenylate Cyclase Nerve Tissue Proteins Trans-Activators G-Protein-Coupled Receptor Kinase 3 GTP-Binding Proteins Pirinitramide Proteins Calcium Pertussis Toxin Arrestins Saccharomyces cerevisiae Proteins Benzamides Piperazines Street Drugs Cocaine Anesthetics, Local Protein Isoforms Ethanol Oligodeoxyribonucleotides Receptors, sigma Phosphoproteins Escherichia coli Proteins Freund's Adjuvant

Analytical, Diagnostic and Therapeutic Techniques and Equipment41

Pain Measurement Analgesia Opiate Substitution Treatment Binding, Competitive Prescription Drug Misuse Models, Molecular Injections, Spinal Drug Overdose Radioligand Assay Transfection Cloning, Molecular Pain Management Mutagenesis, Site-Directed Sequence Alignment Crystallography, X-Ray Injections, Intraventricular Two-Hybrid System Techniques Electrophoresis, Polyacrylamide Gel Drug Prescriptions Self Administration Microinjections Models, Biological Substance Abuse Detection Double-Blind Method Surface Plasmon Resonance Blotting, Western Analgesia, Patient-Controlled Analysis of Variance Electroacupuncture Immunoprecipitation Electric Stimulation Immunohistochemistry Autoradiography Amino Acid Substitution Inappropriate Prescribing Drug Administration Routes Electrophoretic Mobility Shift Assay Drug Administration Schedule Analgesia, Epidural Acupuncture Analgesia Disease Models, Animal

Psychiatry and Psychology17

Opioid-Related Disorders Pain Substance Withdrawal Syndrome Morphine Dependence Heroin Dependence Pain Threshold Behavior, Animal Substance-Related Disorders Conditioning, Operant Nociception Behavior, Addictive Cocaine-Related Disorders Motor Activity Neonatal Abstinence Syndrome Euphoria Reward Reinforcement (Psychology)

Phenomena and Processes46

Protein Binding Pain Binding Sites Drug Tolerance Amino Acid Sequence Dose-Response Relationship, Drug Base Sequence Binding, Competitive Protein Structure, Tertiary Kinetics Pain Threshold Sequence Homology, Amino Acid Promoter Regions, Genetic Transfection Drug Interactions Mutation Signal Transduction Protein Conformation Time Factors Gene Expression Regulation Dimerization Phosphorylation Stereoisomerism Amino Acid Motifs Protein Structure, Secondary Substrate Specificity Molecular Weight Plasmids Brain Chemistry Molecular Structure Protein Transport Hot Temperature Nucleic Acid Conformation Molecular Conformation Motor Activity Structure-Activity Relationship Conserved Sequence Gene Expression Protein Multimerization Mutagenesis Sequence Deletion Protein Interaction Domains and Motifs Enzyme Activation Amino Acid Substitution Regulatory Sequences, Nucleic Acid Tissue Distribution

Disciplines and Occupations1

Immunohistochemistry

Anthropology, Education, Sociology and Social Phenomena1

Drug and Narcotic Control

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care9

Pain Management Drug Prescriptions Substance Abuse Detection Drug and Narcotic Control Double-Blind Method Analysis of Variance Hot Temperature Substance Abuse Treatment Centers Inappropriate Prescribing

Geographicals1

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Psychiatry and Psychology Phenomena and Processes Anthropology, Education, Sociology and Social Phenomena Information Science Health Care

Receptors, Opioid, mu Receptors, Opioid Analgesics, Opioid Receptors, Opioid, delta Receptors, Opioid, kappa Opioid Peptides Narcotic Antagonists Naloxone Opioid-Related Disorders Naltrexone Enkephalins Enkephalin, Ala(2)-MePhe(4)-Gly(5)-Morphine Narcotics Enkephalin, D-Penicillamine (2,5)-Endorphins Dynorphins Buprenorphine Enkephalin, Leucine Protein Binding Enkephalin, Leucine-2-Alanine Diprenorphine Pain Molecular Sequence Data beta-Endorphin Binding Sites Benzeneacetamides Analgesics Morphinans Drug Tolerance Fentanyl Methadone Amino Acid Sequence Pain Measurement Hydromorphone Benzomorphans Pyrrolidines Substance Withdrawal Syndrome Analgesia Dose-Response Relationship, Drug Opiate Substitution Treatment Base Sequence Binding, Competitive Heroin Ligands Chronic Pain Levorphanol Prescription Drug Misuse Cell Line Protein Structure, Tertiary Oligopeptides Morphine Dependence Butorphanol Prescription Drugs Models, Molecular Rats, Sprague-Dawley Kinetics Diterpenes, Clerodane DNA-Binding Proteins Heroin Dependence Oxymorphone Ethylketocyclazocine Morphine Derivatives Injections, Spinal Recombinant Proteins Pain, Intractable Benzylidene Compounds Drug Overdose Cyclazocine Pain Threshold Analgesics, Non-Narcotic Recombinant Fusion Proteins Transcription Factors Radioligand Assay CHO Cells Periaqueductal Gray Carrier Proteins D-Ala(2),MePhe(4),Met(0)-ol-enkephalin Sequence Homology, Amino Acid Cricetinae Guanosine 5'-O-(3-Thiotriphosphate)Hyperalgesia Alfentanil Nalbuphine Hydrocodone Promoter Regions, Genetic Transfection Tramadol Drug Interactions DNA Mutation Signal Transduction Protein Conformation Brain Cloning, Molecular Sufentanil Loperamide Time Factors Opiate Alkaloids Piperidines

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