Protein BindingMolecular Sequence DataBinding SitesAmino Acid SequenceBase SequenceProtein Structure, TertiaryDNA-Binding ProteinsCell LineRecombinant ProteinsModels, MolecularTranscription FactorsPromoter Regions, GeneticKineticsBinding, CompetitiveRecombinant Fusion ProteinsCarrier ProteinsMutationSequence Homology, Amino AcidDNACells, CulturedProtein ConformationNuclear ProteinsLigandsGene Expression RegulationRNA, MessengerTransfectionSignal TransductionEscherichia coliCloning, MolecularHeLa CellsMutagenesis, Site-DirectedBacterial ProteinsCytokinesInterleukinsCrystallography, X-RayInterleukin-6Membrane ProteinsAntibodies, MonoclonalAmino Acid MotifsSequence AlignmentRNA-Binding ProteinsRepressor ProteinsDimerizationPeptide FragmentsTwo-Hybrid System TechniquesElectrophoresis, Polyacrylamide GelPhosphorylationPeptidesDNA PrimersReceptors, InterleukinReceptors, Cell SurfaceSurface Plasmon ResonanceTrans-ActivatorsPlasmidsInterleukin-1COS CellsCell MembraneMacromolecular SubstancesProtein Structure, SecondaryMolecular WeightCattleInterleukin-10Models, BiologicalProteinsSubstrate SpecificityCell NucleusInterleukin-1betaMice, Inbred C57BLBlotting, WesternCricetinaeTumor Cells, CulturedInterleukin-13Interleukin-2Nucleic Acid ConformationInterleukin-4Saccharomyces cerevisiaeCHO CellsTumor Necrosis Factor-alphaDNA, ComplementaryElectrophoretic Mobility Shift AssaySaccharomyces cerevisiae ProteinsCell Line, TumorGene ExpressionConserved SequencePhosphoproteinsEnzyme-Linked Immunosorbent AssaySequence DeletionProtein Interaction Domains and MotifsMice, Inbred BALB COligodeoxyribonucleotidesAdaptor Proteins, Signal TransducingT-LymphocytesRabbitsMice, KnockoutMembrane GlycoproteinsInterleukin-8Protein TransportConsensus SequenceEscherichia coli ProteinsMutagenesis