Ubiquitin-Protein LigasesUbiquitinLigasesUbiquitinsUbiquitin-Conjugating EnzymesAngelman SyndromeUbiquitinationUbiquitin-Protein Ligase ComplexesEndosomal Sorting Complexes Required for TransportProteasome Endopeptidase ComplexCullin ProteinsAnaphase-Promoting Complex-CyclosomeSKP Cullin F-Box Protein LigasesMolecular Sequence DataAmino Acid SequenceProtein BindingCarbon-Nitrogen LigasesPolyubiquitinF-Box ProteinsUbiquitin ThiolesteraseMutationUbiquitin-Activating EnzymesS-Phase Kinase-Associated ProteinsFatty Acid Synthase, Type IISubstrate SpecificityBiotinylationProtein Structure, TertiarySaccharomyces cerevisiae ProteinsRNA Ligase (ATP)Cell LineProteolysisCell Cycle Proteinsbeta-Transducin Repeat-Containing ProteinsSequence Homology, Amino AcidSaccharomyces cerevisiaePeptide SynthasesBiotinCarrier ProteinsF-Box MotifsCysteine EndopeptidasesMultienzyme ComplexesProtein Processing, Post-TranslationalHeLa CellsBase SequenceRecombinant Fusion ProteinsThioctic AcidRepressor ProteinsRING Finger DomainsMultiprotein ComplexesUbiquitin CTranscription FactorsHEK293 CellsAcetyl-CoA CarboxylaseProteinsVon Hippel-Lindau Tumor Suppressor ProteinDNA LigasesHydroxyapatitesModels, MolecularTwo-Hybrid System TechniquesDNA-Binding ProteinsAmino Acid MotifsInhibitor of Apoptosis ProteinsProtein StabilityAdenovirus E4 ProteinsNuclear ProteinsRecombinant ProteinsBinding SitesImmunoprecipitationSignal TransductionProto-Oncogene Proteins c-cblLysineUbiquitinated ProteinsPolynucleotide LigasesProtein TransportModels, BiologicalRNA InterferenceEscherichia coliAdaptor Proteins, Signal TransducingUbiquitin-Specific ProteasesRNA, Small InterferingPeptide HydrolasesBacterial ProteinsSUMO-1 ProteinTransfectionCell Line, TumorPhosphorylationIntracellular Signaling Peptides and ProteinsCloning, MolecularTumor Suppressor ProteinsProteasome InhibitorsElectrophoresis, Polyacrylamide Gelvif Gene Products, Human Immunodeficiency VirusImmunoblottingEndopeptidasesCell CycleCarbon-Nitrogen LyasesCyclin-Dependent Kinase Inhibitor ProteinsCOS CellsSmall Ubiquitin-Related Modifier ProteinsSequence Alignment