The resulting glyconanomaterials have shown significant increase in the binding affinity to specific lectins through forming crosslinked agglomerates, by up to several orders of magnitudes compared to the free carbohydrate ligands due to multivalent interactions ( Liyanage and Yan 2020 ). (frontiersin.org)
Specific binding, which accounted for greater than 90% of total counts bound to the sections, was saturable, of high affinity, and stereoselective, having the same pharmacologic characteristics as binding to homogenates prepared from the same lungs. (nih.gov)
The effects of linker length on binding affinity and degree of aggregation have been examined in the antifluorescein 4-4-20 and anticarcinoma CC49 single-chain Fvs. (nih.gov)
gamma-aminobutyric acid (GABA) acted as an uncompetitive inhibitor of the binding of [35S]TBPS, decreasing both the number of binding sites and the affinity of TBPS. (nih.gov)
Inhibition1
SENP1 inhibition by lactate stabilizes SUMOylation of two residues on APC4, which drives UBE2C binding to APC/C. This direct regulation of APC/C by lactate stimulates timed degradation of cell cycle proteins, and efficient mitotic exit in proliferative human cells. (nature.com)
Assay3
Methods are described for introducing the cyclase reaction mixture directly into a protein binding assay for the cyclic nucleotide without purification of cyclic AMP. (elsevierpure.com)
Maguire, ME & Gilman, AG 1974, ' Adenylate cyclase assay with adenylyl imidodiphosphate and product detection by competitive protein binding ', BBA - Enzymology , vol. 358, no. 1, pp. 154-163. (elsevierpure.com)
The Access Total T3 assay is a competitive binding immunoenzymatic assay. (cdc.gov)
Noncovalent2
We investigated the interactions of noncovalent complexes of single-wall carbon nanotubes that are wrapped by disaccharide lactose-containing glycopolymers with the specific carbohydrate-binding proteins. (frontiersin.org)
Specifically, noncovalent complexes of the oligopeptide-binding protein, OppA, bound to either (Ala)3 or LysTrpLys were electrosprayed from aqueous buffer solution into a 9.4 tesla Fourier transform ion cyclotron resonance mass spectrometer. (ox.ac.uk)
MicroM2
The ICYP was incubated with cryostat sections of microscopically normal human lung method on microscope slides for 2 h at 37 degrees C. Nonspecific binding was determined by incubating adjacent serial sections in the presence of 200 microM (-)-isoproterenol. (nih.gov)
in the presence of 10 microM GABA, Ro5-4864 enhanced binding to a maximum value of 170% of control. (nih.gov)
Complexes2
Of the resulting antigen/antibody complexes, the T3 analogue/antibody complexes are bound to the streptavidin coated solid phase. (cdc.gov)
Separation in a magnetic field and washing removes the sample T3/antibody complexes and other materials not bound to the solid phase. (cdc.gov)
Interactions3
The CLM uses topo-graphically structured competitive and cooperative interactions in a layered network to partition a set of input features into salient groups. (mit.edu)
The synthesized compound also shows strong binding interactions with DNA and BSA in comparison with coumarin. (bvsalud.org)
These results indicate the reciprocal allosteric interactions between a binding site for pyrethroids, a binding site for Ro5-4864, the GABA recognition moiety and the binding site for TBPS in the brain of trout. (nih.gov)
Ligands1
The present in-trap clean-up technique may prove especially useful for identifying and screening the combinatorial library ligands most strongly bound to a receptor in the gas phase. (ox.ac.uk)
Proteins2
Sample is added to a reaction vessel with a stripping agent to dissociate T3 from the binding proteins. (cdc.gov)
A sample is added to a reaction vessel with anti-thyroxine antibody, thyroxine-alkaline phosphatase conjugate, and paramagnetic particles coated with goat anti-mouse capture antibody and a stripping agent to dissociate all T4 from binding proteins. (cdc.gov)
Additionally1
However, the mechanism of interference remained unclear, in particular since all D/N Vif mutants were unable to bind Cul5 and some mutants additionally failed to bind A3G, ruling out competitive binding to A3G or the E3 ubiquitin ligase complex as the sole mechanism. (nih.gov)
Increased aggregation1
Interestingly, an increased aggregation of nanotubes was also observed when interacting with a glucose (Glc) specific lectin, likely due to the removal of Glc groups from the surface of nanotubes resulting from the potential binding of the lectin to the Glc in the glycopolymers. (frontiersin.org)
Receptor2
31. Covalent binding of quinones activates the Ah receptor in Hepa1c1c7 cells. (nih.gov)
A public meeting of an independent Expert Panel was convened on May 21-22, 2002, at the Sheraton Imperial Hotel, Research Triangle Park, NC to review the current status of in vitro methods used to measure estrogen and androgen receptor binding and estrogen and androgen transcriptional activation assays. (nih.gov)
Bids5
Binding Bids Bill now sitting at 64 co-sponsors, AIR Act at 45 backers. (hme-business.com)
HME owner, VGM's Gallagher ask longtime industry ally to back audit reform, binding bids bill. (hme-business.com)
Consumer group organizes a Binding Bids sign-on letter to Congress backed by 25 supporting organizations. (hme-business.com)
More lawmakers back binding bids and audit reform bills, but more needed. (hme-business.com)
Sept. 9-10 lobbying effort will support audit reform, binding bids bill. (hme-business.com)
Analyze2
The goal of the current study was to revisit the mechanism of D/N interference by Vif mutants and analyze the possible involvement of core binding factor beta (CBFβ) in this process. (nih.gov)
The piecewise linear dynamics of the CLM allows a linear eigensubspace analysis, which we use to analyze the dynamics of binding in conjunction with annealing. (mit.edu)
Structural1
The nature of interaction, binding parameters and structural variations of BSA in the presence of the synthesized compound and coumarin have been evaluated using several usefull spectroscopy approaches such as UV -Vis, time resolved and stady state flurescence. (bvsalud.org)
Degrees1
Spiral-bound is the book printing format you'll want for many manuals, reports, cookbooks, directories, planners, and music books with pages that need to be kept open 360 degrees. (acutrack.com)
Reaction1
After incubation in a reaction vessel, materials bound to the solid phase are held in a magnetic field while unbound materials are washed away. (cdc.gov)
Supplements3
The purpose of this letter RFA is to enable the NCI Community Network Program (CNP) grantees to submit competitive supplements for pilot projects as part of the Community Network Program RFA-CA-05-012 requirements. (nih.gov)
The NCI intends to commit approximately $2,000,000 in FY 2006 to fund up to 27 competitive supplements in response to this announcement. (nih.gov)
The purpose of this letter RFA is to solicit competitive supplements from the NCI Community Network Program (CNP) awardees for pilot projects in community based participatory research to reduce health disparities as part of the Community Network Program RFA-CA-05-012 requirement. (nih.gov)
Game1
One of the familiar and original maps of the game, Bind, is making its return to VALORANT competitive queue and the official map pool with the release of Act III Episode VI. (tracker.gg)
Compound1
The DNA binding study shows groove binding interaction of the synthesized compound with CT- DNA . (bvsalud.org)
Complex2
We find that accumulated lactate binds and inhibits SENP1 by forming a complex with zinc in the SENP1 active site. (nature.com)
Competitive binding of USF1 with AhR.Arnt complex. (nih.gov)
Back1
Bind is back at the start of Act III. (tracker.gg)
Unoccupied binding sites on the anti-T3 antibody are bridged to the particle through the T3 analog. (cdc.gov)
Model1
We present a recurrent neural network for feature binding and sensory segmentation: the competitive-layer model (CLM). (mit.edu)
Specific1
The terminal galactose (Gal) of glycopolymers binds to the specific lectin as expected. (frontiersin.org)
Application1
Health Emergency Preparedness Cooperative Agreement AA154 and will be distributed by use of a competitive application process. (cdc.gov)
Process1
Consultancies are time-bound, project-related engagements that run through a competitive bid process. (habitat.org)
Price1
Regardless of the trim size you need, Acutrack can print your spiral book at high quality for a competitive price. (acutrack.com)
Nature1
These roles are typically time-bound, field-based in nature, may have national or multi-country scopes and are contingent upon Habitat being awarded the funding. (habitat.org)
Benefits1
Employment opportunities with our headquarters may be part- or full-time with competitive benefits and span all levels and departments of the organization. (habitat.org)
Recent2
There have been some recent mails about making new releases of the wnck bindings, but it is unclear what the current status is. (gnu.org)
CS GO Binds : Counter-Strike Global Offensive (CS GO) is one of the most played First Person Shooter (FPS) games of recent times. (mapmodnews.com)
Books2
Acutrack is the Best Choice to Print Your Spiral-Bound Book We've printed spiral books with excellent results for companies and self-publishers of all types, and you can choose from various time sizes, paper qualities, and cover stocks. (acutrack.com)
We print affordable, high-quality coil-bound books with the goal of improving our clients' sales and profitability. (acutrack.com)
Letter1
The Letter of Intent is not a binding agreement, nor will the absence of one exclude an awardee from applying. (cdc.gov)
Analysis2
Synthesis of water-soluble novel bioactive pyridine-based azo coumarin derivative and competitive cytotoxicity, DNA binding, BSA binding study, and in silico analysis with coumarin. (bvsalud.org)
Our analysis started from LINCS KINOMEscan data, which is a "benchmark" kinase target competitive binding bioassay. (iscb.org)
Business1
One provider takes stock of the true personal and professional cost paid when a home medical equipment business has to fight for survival in the face of CMS's competitive bidding and reimbursement cuts. (hme-business.com)
Projects1
This document provides guidance for applying for competitive funding for demonstration projects designed to further pandemic influenza preparedness and response. (cdc.gov)
High1
Our print turnarounds are fast, prices are competitive, and you'll be impressed with the high quality. (acutrack.com)