• The S1 subunit contains a receptor binding domain or RBD that binds with the specific receptors, while the S2 subunit helps membrane fusion. (openaccesspub.org)
  • The crucial step of receptor binding depends on the closed and open conformations of the S-Protein ectodomain trimer 10 , 11 . (openaccesspub.org)
  • or actively by prior immunization of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody complexes which bind to the antigen receptor sites of the T-cells and block their cytotoxic activity. (lookformedical.com)
  • In analogy with histo-blood group A antigen, Forssman (Fs) antigen terminates with α3- N -acetylgalactosamine and can be used by pathogens as a host receptor in many mammals. (ashpublications.org)
  • In our body, the function of T cells and B Cells is to recognize specific non-self antigens, during a process known as antigen presentation. (wellnessadvantage.com)
  • This host-specific binding of the spike protein initiates coronavirus infection. (openaccesspub.org)
  • It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs. (lookformedical.com)
  • The approximate areas of the HSV-2 genes encoding HSV-2 type-specific CD4+ antigens have been decided through the use of HSV-1 x HSV-2 intertypic recombinant virus and embrace the approximate map areas 0.30 to 0.46, 0.59 to 0.67, 0.67 to 0.73, and 0.82 to 1.Zero items. (herpes-pics.com)
  • In this experiment, we observed cytokine gene expression changes in Gallus gallus embryo after challenge with Delta SARS-CoV-2 RBD spike protein antigen, from a concentration of 10 µg/mL to a series of highly diluted forms in ethanol, along with controls. (openaccesspub.org)
  • Attogram and zeptogram level concentrations of the antigen showed consistently remarkable up-regulation of INF-α among different cytokine gene expressions. (openaccesspub.org)
  • INF-β gene expressions at the zeptogram level of the antigen showed consistent changes, although not so outstanding. (openaccesspub.org)
  • A newly described polymorphism in the GBGT1 gene activates the encoded enzyme to synthesize Forssman antigen. (ashpublications.org)
  • Following activation, B cells and T cells leave a lasting legacy of the antigens they have encountered, in the form of memory cells. (wellnessadvantage.com)
  • The natural binding of coronaviruses' spike (S) glycoprotein occurs with various receptors - ACE2, APN, DPP4, CEACAM, Sia, and O-acSia of human cells. (openaccesspub.org)