Bind chelating agents. Medical search. Frequent questions

Chelating agents for the binding of metal ions to macromolecules. (jax.org)
Chelating agents" are ligands that bind metal ions through more than one bond. (wikipedia.org)
This white, water-soluble solid is widely used to bind to iron and calcium ions. (brenntag.com)
It binds these ions as a hexadentate ('six-toothed') chelating agent. (brenntag.com)
The additive can act on the ions in the solution (known as chelating agents), binding them and limiting the amount of solids that form. (databasefootball.com)
Oxalate can bind barium ions in the solution, but is this how it impacts? (databasefootball.com)
In earth science, chemical weathering is attributed to organic chelating agents, e.g. peptides and sugars , that have the ability to solubilize the metal ions in minerals and rocks. (wikidoc.org)
This is called chelating agent, and function of this agent is to binding the ions like Calcium and magnisium so tgihtly and that they can not bind with others. (assignmenthelp.net)
Ethylene-Diamine-Tetra-Acetic Acid (EDTA) is a chelating agent with antioxidant properties and can bind to free-flowing metal ions in the bloodstream, forming a chemical bond that can facilitate the removal of these complexes. (qfc.com)

EDTA is a chelating agent used in various industries including water treatment, food, cleaning and other industrial applications. (brenntag.com)
One such agent, Na 2 EDTA, was formerly used for treatment of hypercalcemia, but its use has become infrequent because of concerns regarding nephrotoxicity and because of the availability of less toxic alternatives ( 3 ). (cdc.gov)
Initial medication orders included IV Na 2 EDTA and oral succimer (an agent primarily used for treatment of lead poisoning). (cdc.gov)
During selective precipitation, ethylenediaminetetraacetic acid (EDTA) is used as a stabilizing agent to prevent iron and phosphorus co-precipitation. (rsc.org)
Citric acid, phosphoric acid, ethylenediaminetetraacetic acid (EDTA) and tetracycline hydrochloride (TTC) 10 are considered the most used agents for this purpose. (bvsalud.org)
The enzyme was found to be inactivated by the metal chelating agent, ethylene diamine tetracetate (EDTA) at 5 X 10-3 and 5 X 10-4 M concentrations. (who.int)

Such chelating agents include the porphyrin rings in hemoglobin or chlorophyll and the Fe 3+ -chelating siderophores secreted by microorganisms . (wikidoc.org)
These compounds represent a specific means by which potent antimicrobial agents, covalently linked to iron-chelating siderophores, can be actively transported across the outer membrane of gram-negative bacteria. (rcsb.org)
The structural information derived from this study provides novel insights into the diverse array of antibiotic moieties that can be linked to the distal portion of iron-chelating siderophores and offers a structural platform for the rational design of hydroxamate-type siderophore-antibiotic conjugates. (rcsb.org)

Chelation therapy involves injecting a type of medication called a chelator or chelating agent. (healthline.com)
A "chelator" helps to bind ingredients). (manbarsoap.com)

Because chelating agents bind to metals through more than one coordination site, such ligands bind more tenaciously than unidentate ligands (like water). (wikidoc.org)
The concentration of the chemicals tested as anti-biofilm agents was chosen based on cytotoxicity assays: the highest non-cytotoxic chemical concentration was used for biofilm inhibition assays, with dendrimer concentration 10-fold higher than polyamino-phenolic ligands. (frontiersin.org)

A variety of chelating agents are used, such as peptides and amino acids derived from hydrolysed soy proteins, which form amino acid complexes. (wikipedia.org)
The specific characters of peptides (high bioactivity, high specificity, and low toxicity) have made them attractive therapeutic agents. (intechopen.com)

Penicillamine is a chelating (KEE-late-ing) agent that binds to excess copper and removes it from the blood stream. (cigna.com)

Organic chelating agents form multiple bonds with metals in soil and may reduce P binding with Fe and Al. (confex.com)
The most important is chelation, or the binding and removal of metals and other toxins from the body. (naturalnews.com)
They are both used as chelating agents of heavy metals and other toxins. (naturalnews.com)
The body's natural chelating agent is called metallothienein (MT). This protein binds to toxic metals for delivery to the liver or kidneys for excretion. (naturalnews.com)
Chelating agents also increase excretion of other heavy metals and minerals, such as zinc and, in certain cases, calcium ( 1 ). (cdc.gov)
Chelating agents, especially those intended for use in children, should be effective in reducing lead and other heavy metals from the body without producing substantial adverse effects on levels of critical serum electrolytes, such as calcium. (cdc.gov)
Chelating drugs are only used in acute cases of poisoning because there's a risk that they can also deplete your body of essential minerals, like iron, that it needs to function, or cause the metals to enter your bloodstream, which could lead them to travel to organs like the brain. (everydayhealth.com)
In addition to these adventitious chelators, several are produced to specifically bind certain metals. (wikidoc.org)
Chelators work by binding to metals in the bloodstream. (healthline.com)
Once they're injected into the bloodstream, they circulate through the blood, binding to metals. (healthline.com)
That reference interval, that normal green range, is the level under non -provoked conditions, meaning normal urine, not urine from someone who was just given a chelating drug to provoke the response, to intentionally grab onto heavy metals in the body and pull them into the urine. (nutritionfacts.org)

Thalassaemia is a inherited (mostly autosomal recessive) blood disease that can lead to anemia by causing the formation of abnormal hemoglobin molecules not able to properly bind and release oxygen. (blogspot.com)

Calcium-DTPA (.PDF, 416 KB) and zinc-DTPA (.PDF, 345 KB) are injectable chelating agents used to enhance the excretion of plutonium and other transuranics from the body. (orau.gov)
The fluorophore was absorbed through the tadpole's skin and bound to calcium stored along the larva's notochord. (yale.edu)
Proponents claim that chelators bind to calcium found in plaque, which helps to loosen and remove the buildup. (healthline.com)
The sodium alginate allowed calcium to be absorbed through the intestinal wall while binding most of the strontium, which was excreted out of the body. (radiationdangers.com)

In the late 18th century, antisyphilitic agents contained mercury. (medscape.com)
Before 1990, paints contained mercury as an antimildew agent. (medscape.com)
In medicine, mercury is used in dental amalgams and various antiseptic agents. (medscape.com)
Chelation therapy describes the use of chelating agents to detoxify poisonous metal agents such as mercury , arsenic , and lead by converting them to a chemically inert form that can be excreted without further interaction with the body. (wikidoc.org)
We also have all patients rinse with Bentonite, a chelating agent that binds any loose mercury particles. (winaturaldentist.com)

Fish protein binds more than 90% of the consumed methylmercury so tightly that even the most vigorous cooking methods (eg, deep-frying, boiling, baking, pan-frying) cannot remove it. (medscape.com)
This website contains examples of drugs with CYP enzyme-based and transporter-based interactions but does not include drugs with other mechanisms leading to drug interactions (such as certain interactions affecting drug absorption (e.g., chelating agents, resin-based binders, interactions, and drugs that change gut pH), interactions affecting drug plasma protein binding, or pharmacodynamic interactions). (fda.gov)
[5] Most metal complexes in the environment and in nature are bound in some form of chelate ring, e.g. with " humic acid " or a protein. (wikidoc.org)
MECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). (bvsalud.org)
This indicates that TCR-pMHC binding in cell contacts depends significantly on the local environment and not only on the protein-protein interaction per se. (lu.se)

Radiogardase™ Prussian Blue (.PDF, 420 KB) binds to radiocesium and thallium and enhances their excretion from the body. (orau.gov)
Chelating agents bind lead in soft tissues and are used in the treatment of lead poisoning to enhance urinary and biliary excretion of lead, thus decreasing total lead levels in the body ( 1 ). (cdc.gov)
Deferiprone is an oral iron chelating agent, binding excess iron in the blood and thus making it available to excretion from the body. (blogspot.com)

Most acid soils have a high capacity to bind P strongly as iron and aluminum compounds which can result in low P fertilizer use efficiency. (confex.com)
Increasing regulatory restrictions and consumer negative response to chemical compounds and to the use of antibiotics in agriculture have contributed to the pressure for the development of alternative compounds for use as antimicrobial agents [ 6 ]. (hindawi.com)
Chlorella is a green algae and spirulina is a blue-green algae which contain chlorophyllin and other nutrients that bind toxic compounds in the gut. (naturalnews.com)
Soil is a major reservoir for xenobiotic compounds as it possesses an ability to bind various chemicals [ 2 ]. (omicsonline.org)

Therapeutic approaches based on the use of ferrochelating agents such as lactoferrin combined with antimicrobial drugs may help to counteract the reduced efficacy of current antibiotics. (nih.gov)
This review paper will focus on the plant-derived products as antimicrobial agents for use in food preservation and to control foodborne pathogens in foods. (hindawi.com)
Antimicrobial agents have been predominantly isolated from bacteria and fungi and either produced through fermentation or produced chemically [ 1 ]. (hindawi.com)

VWF binds to receptors on the platelet surface membrane (glycoprotein Ib/IX). (msdmanuals.com)
A low level of signaling was also obtained when functionalizing the blocked SLBs with adhesion molecules binding to receptors on the T cell. (lu.se)

Mehlich-1 and Mehlich-3 extractable P levels, before and after incubation, were also measured to evaluate the effects of the chelating agents on routine soil analysis results. (confex.com)
241 as influenced by chelating agent, lime, and soil type. (cdc.gov)

It is treated by removing excess iron from the blood, either by removing blood from the body (phlebotomy) or by taking a medicine (chelating agent) that binds to and removes iron from the body. (wellspan.org)

CXCR4 binding efficacy and toxicity studies were performed on CXCR4 expressing cancer cell-lines. (aacrjournals.org)

To suppress iron (Fe) interferences with the PAN reagent, the Fe(III) masking agents deferoxamine mesylate (DFO-B) or disodium 4,5-dihydroxy-1,3-benzenedisulfonate (Tiron) were added and their Fe masking efficiencies were investigated. (nature.com)

Treatment of the particulate enzyme with 0.1 present and 0.5 present (v/v) of the nonionic surface active agent, Triton X - 100, solubilized 71 percent and 76 percent of the invertase. (who.int)

Albomycins are broad-host range antibiotics that consist of a hydroxamate-type iron-chelating siderophore, and an antibiotically active, thioribosyl pyrimidine moiety. (rcsb.org)
The economic and social cost of the disease is high owing to the patient's life- long need for monthly blood transfusions and treatment with iron chelating agent. (who.int)

Chelate" is jargon for metal complexes of chelating agents. (wikipedia.org)

The term is reserved for complexes in which the metal ion is bound to two or more atoms of the chelating agent, although the bonds may be any combination of coordination or ionic bonds . (wikidoc.org)

Methods: Standardization of conjugation of AMD3100 with bifunctional chelating agents (DTPA, NOTA etc. (aacrjournals.org)
Despite the well-described uses of these agents, there is lack of standardization of the procedures employed by clinicians and researchers. (bvsalud.org)

However, hospital formularies usually stock multiple chelation agents. (cdc.gov)
There are no published peer review publications regarding the efficacy of chelation agents for the treatment of autism. (wikidoc.org)

If you experience acute poisoning, you will most likely be treated with chelating agents, which bind to the metal and are then excreted in your urine. (everydayhealth.com)
Chelating agents have been useful in treating acute lead poisoning by removing lead from the body and reducing dangerously high blood lead levels. (cdc.gov)

Plant oils and plant extracts have been utilized for thousands of years, serving many purposes, such as food preservatives and medical therapeutic agents [ 2 ]. (hindawi.com)

Binds hard water and other minerals to allow the cleaning actives to perform more effectively. (rbnainfo.com)

2000. Threshold limit values for chemical substances and physical agents and biological exposure indices. (cdc.gov)
An improvement of biological response on root surface after conditioning with demineralizing agents has been described9. (bvsalud.org)
In vivo human 9 histological studies have shown improved biological response when decalcifying/chelating agents are used to condition the root surface. (bvsalud.org)

Proprietary Formula: The secret to our efficacy is what we include that others do not, a powerful chelating agent. (theprodukkt.com)

To better understand how, and if, adhesion molecules of different lengths influences TCR-pMHC binding the 2D Kd of TCR-pMHC in the presence of differently-sized adhesion molecules was studied. (lu.se)
Furthermore, even for height-matched adhesion molecules the 2D Kd of the TCR-pMHC interaction was found to be dependent on the relative density fraction of TCR to adhesion molecules, with low fractions of TCR molecules giving 2-3 times weaker binding. (lu.se)

Unexpectedly, this antibiotic assumes two conformational isomers in the binding site of FhuA, an extended and a compact form. (rcsb.org)

We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associated with several neurological disorders. (bvsalud.org)

To our knowledge, this represents the first structure of an antibiotic bound to its cognate transporter. (rcsb.org)

Inorganic lead binds to the red blood cells which transport it throughout the body, allowing it to be stored in the bone, vital organs and tissues. (cdc.gov)

You see a lot of correlational studies like this, speculating about "the possibility that one of the hidden agents spurring the rise in autism" is something within the food supply, especially industrialized meat production, particularly poultry. (nutritionfacts.org)

Surface-active agent helps remove dirt, stains, and bad smells. (rbnainfo.com)
Extrinsic stains are defined as stains located on the outer surface of the tooth structure and caused by topical or extrinsic agents. (medscape.com)

Depsolube ACMS offers a 3 in 1 function - anti-crease, softener and hydrophilicity agent. (crodaindustrialspecialties.com)

Health-care providers who are unfamiliar with chelating agents and are considering this treatment for lead poisoning should consult an expert in the chemotherapy of lead poisoning. (cdc.gov)

A large pool of research has been aimed at characterizing this interaction by measuring the binding kinetics and relating it to the T cell response. (lu.se)

This testimony before the Subcommittee on Manpower, Compensation, and Health and Safety dealt with the effects of occupational lead (7439921) exposure on human health and the special risks posed by prophylactic use of chelating agents among lead workers. (cdc.gov)

Catechol surfactants such as poly-norepinephrine (pNE) are biomolecules that are used as material-independent binding, local chelating and wetting agents due to their multi-functional side groups. (programmaster.org)

Powerful non-cresylic low foam wetting agent particularly designed for the mercerising process. (crodaindustrialspecialties.com)

In many T cell activation studies, the SLB contains the nickel-chelating lipid DGS-NTA(Ni) to functionalize the SLB with histidine-tagged proteins. (lu.se)

These are the proteins and binds with active site of amylase, it is nutritional supplements. (assignmenthelp.net)

This is measured on individual cell-SLB contacts, providing an accurate new means of measuring binding affinity and to study differences in the 2D Kd in the cell population. (lu.se)

Clobazam decreases the frequency of the LGS seizures by potentiating GABAergic neurotransmission, trough the binding of the GABA A receptor at the benzodiazepine site. (blogspot.com)

If the poisonous substance is unknown, the patient's case history and clinical features may help determine the causative agent, which is important for the selection of a proper antidote (if available). (amboss.com)

Safeguard your body and protect it from radiation damage by taking at least one chelating agent such as chlorella , modified citrus pectin, or zeolite. (naturalnews.com)
Canadian researchers reported that sea vegetables contained a polysaccharide substance that selectively bound radioactive strontium and helped eliminate it from the body. (radiationdangers.com)

Anatomy22

Organisms17

Chemicals and Drugs99

Analytical, Diagnostic and Therapeutic Techniques and Equipment38

Phenomena and Processes80

Information Science3

Health Care1

Ions9

EDTA6

Siderophores3

Chelator2

Ligands2

Peptides2

Penicillamine1

Metals11

Hemoglobin1

Calcium4

Mercury5

Protein5

Excretion3

Compounds4

Antimicrobial3

Receptors2

Soil2

Excess1

Toxicity1

Disodium1

Enzyme1

Iron2

Chelate1

Bonds1

Standardization2

Chelation agents2

Acute2

Therapeutic1

Minerals1

Biological3

Efficacy1

Molecules2

Form1

Findings1

Antibiotic1

Blood1

Autism1

Surface2

Function1

Treatment1

Response1

Effects1

Local1

Powerful1

Studies1

Active1

Study1

Site1

Clinical1

Body2