• Breast calcifications are a common mammographic finding, present on over 80% of images, and they are usually benign. (medscape.com)
  • [ 1 , 2 ] Radiologists who interpret mammograms encounter calcifications on a daily basis (see the images below) and must be able to identify typically benign breast calcifications that do not require biopsy to prevent unnecessary procedures and to reduce patient anxiety. (medscape.com)
  • Finally, on the basis of the interpretation, the radiologist can make an informed decision about whether the calcifications identified are benign and do not require biopsy or whether the appearance of the calcifications warrants biopsy. (medscape.com)
  • 001). The researchers concluded that the rate of calcification change may help discriminate benign from malignant calcifications. (medscape.com)
  • Mammography is limited in evaluating benign calcifications when benign calcifications morphologically overlap with indeterminate or malignant calcifications. (medscape.com)
  • Although screening mammography remains the only modality demonstrated to reduce death from breast cancer, 70-80% of biopsies performed for suspicious mammographic findings (masses and calcifications) are benign. (medscape.com)
  • In a study comparing conspicuity of DCIS to benign calcifications on unenhanced breast CT (bCT), contrast-enhanced breast CT (CEbCT), and mammography, DCIS was found to be more conspicuous than benign microcalcifications on CEbCT. (medscape.com)
  • Lobular calcifications are almost always benign. (radiologyassistant.nl)
  • The mammogram revealed bilateral benign calcification and no other masses or malignancy. (robertkreisman.com)
  • Neuroimaging revealed bilateral basal ganglia calcifications and white matter lesions. (thaimedicalnews.com)
  • Primary familial brain calcification is a condition characterized by abnormal deposits of calcium (calcification) in blood vessels within the brain. (medlineplus.gov)
  • The main signs and symptoms of primary familial brain calcification are movement disorders and psychiatric or behavioral problems. (medlineplus.gov)
  • Other movement problems common in people with primary familial brain calcification include involuntary tensing of various muscles (dystonia), uncontrollable movements of the limbs (choreoathetosis), and an unsteady walking style (gait). (medlineplus.gov)
  • Psychiatric and behavioral problems occur in 20 to 30 percent of people with primary familial brain calcification. (medlineplus.gov)
  • Recent research has indicated that primary familial brain calcification may occur in 2 to 6 per 1,000 people, with many affected individuals not showing signs and symptoms of the condition. (medlineplus.gov)
  • Primary familial brain calcification is caused by mutations in one of several genes. (medlineplus.gov)
  • In about half of individuals with primary familial brain calcification the genetic cause is unknown. (medlineplus.gov)
  • However, it is unclear how the mutations cause primary familial brain calcification. (medlineplus.gov)
  • Other genes known to be associated with primary familial brain calcification also have roles in cell signaling and phosphate homeostasis. (medlineplus.gov)
  • Researchers suggest that calcium deposits lead to the features of primary familial brain calcification by disrupting the connections between the basal ganglia and other areas of the brain, particularly the frontal lobes. (medlineplus.gov)
  • Recently the designation "primary familial brain calcification (PFBC)" has been proposed in opposition to 'secondary' and on the basis of family history (Sobrido et al. (springeropen.com)
  • Figure I.1 - Bilateral Mammogram, May 23, 1985. (iptq.com)
  • Figure I.3 - Bilateral Mammogram, October 26, 1986. (iptq.com)
  • After discovering calcifications on the mammogram, Michel underwent another ultrasound and a biopsy. (philadelphiaeagles.com)
  • Sanifit conducted a phase-IIb trial (CaLIPSO) in 274 patients to assess the effect of SNF472 on slowing arterial calcification, a major risk factor for cardiovascular disease in dialysis patients. (menafn.com)
  • The aim of this paper is to report the autopsy findings of an Idiopathic Infantile Arterial Calcification-new-born male and describe its follow-up. (nih.gov)
  • Microscopic investigation revealed a generalized arterial calcification of all organs. (nih.gov)
  • Idiopathic arterial calcification is primarily a disease of infancy. (nih.gov)
  • It is characterized pathologically by generalized arterial calcification within the internal elastic lamina, associated with intimal fibrous proliferation. (nih.gov)
  • Cranial computed tomography done at the outside hospital shows diffuse cerebral calcifications. (contemporarypediatrics.com)
  • The presence of cerebral calcifications in individuals infected with SARS-CoV-2 has been confirmed by several case reports and studies. (thaimedicalnews.com)
  • It is crucial to consider the possibility of Fahr's syndrome and conduct brain MRIs to check for cerebral calcifications. (thaimedicalnews.com)
  • Intracranial calcifications may occur physiologically or pathologically for many reasons. (springeropen.com)
  • Then, in the year 1922, the first radiographic evidence of intracranial calcifications was brought forth by Weber [ 10 ]. (hindawi.com)
  • Idiopathic basal ganglia calcification (IBGC) is a rare, intractable disease with unknown etiology. (springeropen.com)
  • Idiopathic basal ganglia calcification (IBGC), also called Fahr disease, is a rare and intractable disease. (springeropen.com)
  • We present a case of a 46-year-old man who was admitted for shortness of breath and pleuritic chest pain and was found to have iron deficiency anemia, deep venous thrombosis, and bilateral pulmonary emboli (PE). (hindawi.com)
  • Diffuse calcifications were also observed in bilateral basal ganglia and both hemispheres, more on the left. (springeropen.com)
  • Lobular calcifications usually have a diffuse or scattered distribution, since most of the breast is involved in the process that forms the calcifications. (radiologyassistant.nl)
  • Diffuse irregularity of the vertebrobasilar system, with small basilar distal to the origin of the anterior inferior cerebellar arteries, may be due to atherosclerotic narrowing and or presence of bilateral fetal origin PCAs. (claripacs.com)
  • The macroscopic examination showed a bilateral pleural liquid effusion without any other abnormalities. (nih.gov)
  • Bilateral pleural plaques and/or calcification of the diaphragm are virtually pathognomonic of previous exposure to asbestos. (merckmanuals.com)
  • The association of pleural thickening and calcification with interstitial changes enhances diagnostic accuracy of asbestosis. (cdc.gov)
  • Two with histories of road maintenance work (one had also worked in a local gravel pit) were found with mild bilateral localized pleural changes with calcification and minimal unilateral and bilateral lower lobe interstitial changes that could only be seen by CT scan. (cdc.gov)
  • Vifor Pharma has announced the acquisition of Sanifit Therapeutics, a Spanish clinical-stage cardio-renal biopharmaceutical company focused on treatments for end-stage kidney disease patients with progressive vascular calcification disorders, and Inositec AG, a Swiss company, developing first-in-class non-dialysis treatments for soft tissue and vascular calcification disorders. (menafn.com)
  • Through these acquisitions, Vifor Pharma will be able to serve a continuum of vascular calcification disorders at all stages of CKD. (menafn.com)
  • Acquisition of Sanifit is for the continued clinical development and commercialization of SNF472, a novel, first-in-class intravenously administered inhibitor of vascular calcification, for the treatment of CUA and PAD in patients with end-stage kidney disease. (menafn.com)
  • Inositec's novel asset INS-3001, is a once-daily subcutaneous treatment for patients with vascular calcification disorders PAD and AVS, which are both major contributors to cardiovascular morbidity and mortality in affected patient populations. (menafn.com)
  • With INS-3001 daily subcutaneous dosing, patients with earlier stages of vascular calcification can be optimally treated, while end-stage kidney disease patients will benefit from the three times per week dosing regimen of SNF472. (menafn.com)
  • These acquisitions are a perfect fit for our expanding nephrology pipeline, which now includes vascular calcification inhibition treatments across various stages of non-dialysis CKD and even non-CKD patient populations. (menafn.com)
  • Vifor Pharma will be spearheading the vascular calcification field, emphasizing our strategic focus to bring innovative assets to patients with high unmet medical need as we strive to improve lives of people suffering from serious diseases around the world. (menafn.com)
  • This agreement is a testament to the enduring commitment of our dedicated team and investors, as well as our unique approach to combat vascular calcification, which originated from the University of the Balearic Islands. (menafn.com)
  • This acquisition builds on years of hard work from the entire Inositec team and provides a strong foundation for improving outcomes for patients suffering from cardiovascular and vascular calcification disorders," said Mattias Ivarsson, Founder and Chief Executive Officer of Inositec, adding"Inositec's transition to a clinical-stage company represents an ideal time to partner with Vifor Pharma to accelerate the clinical development of INS-3001. (menafn.com)
  • In 1879, Sturge reported on a case with bilateral facial nevus, vascular deformity, and congenital glaucoma in the right eye and spasms affecting the patient's left side of the body [ 9 ]. (hindawi.com)
  • Imaging findings may include tram track calcifications on CT, pial angiomatosis, and hemicerebral atrophy. (wikipedia.org)
  • Findings of chest radiography performed in the ED showed bilateral hilar lymphadenopathy with dilation of the ascending thoracic aorta ( Figure 1 ). (consultant360.com)
  • Additional findings included multiple bilateral ground-glass and nodular opacities, cardiac enlargement, and coronary artery calcification, suggesting spread of sarcoidosis to the great vessels. (consultant360.com)
  • The patient had bilateral facial nevus as well as unilateral buphthalmos [ 8 ]. (hindawi.com)
  • It has a variable morphology, can be complete or incomplete and may be unilateral or bilateral. (radiopaedia.org)
  • The background fibrous stroma frequently contains coarse calcifications. (cap.org)
  • Since the direct diagnosis of AVM in non-contrast brain-computed tomography (CT) is difficult, the detection of calcification in these regions requires the presence of AVM in the differential diagnosis. (springeropen.com)
  • The initial diagnosis of bilateral elbow synovial chondromatosis was performed by physical examination and imaging report. (biomedcentral.com)
  • For a diagnosis of IBGC, other known causes of calcification, including metabolic, infectious, toxic, or traumatic causes should be excluded (Bonazza et al. (springeropen.com)
  • LEFT: Lobular calcifications: punctate, round or 'milk of calcium' RIGHT: Intraductal calcifications: pleomorph and form casts in a linear or branching distribution. (radiologyassistant.nl)
  • This results in uniform, homogeneous and sharply outlined calcifications, that are often punctate or round. (radiologyassistant.nl)
  • Bilateral seminal vesicle calcification of unknown cause. (uct.ac.za)
  • The seminal vesicles are bilateral, lobulated glands (see the following image). (medscape.com)
  • Figure A ) Cranial magnetic resonance imaging shows generalized parenchymal atrophy and dilation of the bilateral lateral ventricles with patent basal cisterns and coarse supratentorial calcifications involving the cortex, bilateral basal ganglia, and the vermis. (contemporarypediatrics.com)
  • A. Axial cranial CT of case patient showing generalized cortical calcifications with dilation of bilateral lateral ventricles. (contemporarypediatrics.com)
  • B. Axial cranial MRI of case patient showing generalized parenchymal atrophy and dilation of the bilateral lateral ventricles (yellow arrows) with patent basal cisterns and coarse supratentorial calcifications involving the cortex (red arrows), basal ganglia bilaterally, and the vermis. (contemporarypediatrics.com)
  • Top right: A 4.0 × 4.1-cm dilation of the aortic root, and calcifications. (consultant360.com)
  • Skull tomography demonstrated bilateral calcification foci in the cerebral hemispheres. (bvsalud.org)
  • This causes calcification of tissue and loss of nerve cells in the cerebral cortex. (wikipedia.org)
  • High-quality mammography is the best diagnostic tool for the identification of breast calcifications. (medscape.com)
  • Recent studies and case reports have revealed concerning neurological effects of SARS-CoV-2 infections, including the development of brain calcifications. (thaimedicalnews.com)
  • Calcific trochanteric bursitis: resolution of calcifications and clinical remission with non-invasive treatment. (fitterdoors.ru)
  • Bilateral tender cervical lymphadenopathy with two 1 cm lesions on the right, and three 1 cm lesions on the left. (iptq.com)
  • We present a case of coral reef aorta with hemodynamically significant symptomatic aortic stenosis causing intermittent claudication and bilateral cyanosis of the toes. (thieme-connect.com)
  • 17 Sekar N, Manoj S, Jagan J. Suprarenal aortic occlusion due to coral reef calcification: successful endovascular management assisted by intravascular lithotripsy and visceral protection. (thieme-connect.com)
  • Most calcifications in the breast form either within the terminal ducts (intraductal calcifications) or within the acini (lobular calcifications). (radiologyassistant.nl)
  • and calcification or opacities were present in the remainder. (cdc.gov)
  • Bottom right: Bilateral pathognomonic ground-glass opacities seen with sarcoidosis. (consultant360.com)
  • Atherosclerotic calcifications present in the bilateral cavernous carotid arteries with multifocal irregularity. (claripacs.com)
  • Multifocal irregularity of the bilateral M1 segments, with stenosis of the distal right M1. (claripacs.com)
  • The prevalence of X-ray abnormality and bilateral pleural thickening increased with length of exposure. (cdc.gov)
  • Pacientes y métodos Estudio prospectivo en pacientes con derrame pleural a los que se realizó una PET-TAC desde octubre de 2013 hasta octubre de 2019 (cohorte de referencia). (bvsalud.org)
  • The altered signaling may result in an abnormally large amount of calcium entering the cells that line blood vessels in the brain, leading to calcification of these blood vessels. (medlineplus.gov)
  • The haemangioma present on the surface of the brain is in the vast majority of cases on the same side as the birth mark and gradually results in calcification of the underlying brain and atrophy of the affected region. (wikipedia.org)
  • HDBSCC is an autosomal recessive disorder with a distinctive phenotype comprising hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. (nih.gov)
  • The arcuate foramen develops by calcification of the posterior atlanto-occipital membrane . (radiopaedia.org)
  • There are fetal origins of the bilateral posterior cerebral arteries. (claripacs.com)
  • A neurobehavioral syndrome associated with bilateral medial temporal lobe dysfunction. (bvsalud.org)
  • MRI bilateral hip joint shows abnormal bone marrow edema involving bilateral acetabulum and subchondral portion of right sacral ala. (neuroradiologycases.com)
  • CEbCT may have an advantage over mammography by reducing false positive examinations when calcifications are analyzed. (medscape.com)
  • In this article, we present a 47-year-old case of hemispheric AVM accompanied by bilateral basal ganglia calcification. (springeropen.com)
  • In this article, we aimed to present the imaging features of a patient with hemispheric proliferative type AVM with bilateral basal ganglia and subcortical calcification. (springeropen.com)
  • Bilateral lentiform nuclear calcifications are present. (bayloraids.org)
  • From the literature, it can be found that heterogeneous breast densities make masses more challenging to detect and classify compared with calcifications. (jmir.org)
  • Susceptibility weighted imaging (SWI) sequence showed no bleeding in the AVM neighborhood and SWI and phase images confirmed the presence of the calcifications (Fig. 3 ). (springeropen.com)
  • These calcifications can occur rapidly in rare cases or gradually over time in most cases. (thaimedicalnews.com)
  • The report introduced a case about synovial chondromatosis in bilateral elbow found in a 14-year-old girl, which is rarely involved in bilateral elbow and rarely found in adolescents. (biomedcentral.com)
  • Our case describes a 14-year-old female gymnast with bilateral elbow synovial chondropathy. (biomedcentral.com)
  • These calcifications are extremely variable in size, density and form (i.e. pleomorphic from the Greek pleion 'more' and morphe 'form' ). (radiologyassistant.nl)
  • In arteriovenous malformations (AVMs), calcification is not uncommon and is usually detected in the lesion vessel walls and surrounding parenchyma. (springeropen.com)
  • However, rarely calcifications can also be seen in bilateral basal ganglia and especially in watershed areas, which are far from the lesion. (springeropen.com)
  • Bilateral basal ganglion calcification and subcortical calcifications far from the lesion have rarely been reported. (springeropen.com)
  • From the very beginning, Sanifit has been a pioneer of new approaches to treat calcification disorders, a huge area of unmet need. (menafn.com)
  • Il s'agit de la première série de cas du syndrome de Sanjad-Sakati confirmés génétiquement en Jordanie. (who.int)