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  • metabolism
  • Our lead compound, developed at the National Institute on Aging, was 2-deoxyglucose, an analogue of the native sugar, that acted as a glycolytic inhibitor, having limited metabolism and actually reducing overall energy flow--analogous to CR. (isharonline.org)
  • organic
  • Thus, heterocyclic compounds play an important role in organic compounds especially in organic medicines. (chemicalbook.com)
  • the compound is further comprised of M as a hydroxonium, a nitrosonium NO + , an ammonium -NH 4 + , a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. (google.com)
  • protein
  • These results indicate that in some cellular context, the cell sensitivity to PRIMA-1 could depend on the abolition of a gain-of-function activity of the mutated p53, through a protein degradation pathway specifically induced by this compound. (biomedsearch.com)
  • For example, heterocyclic structure exists in chlorophyll in plants, hemoglobin in animal blood, alkaloids and glycosides as the active ingredient in herbs, some antibiotics and vitamins, certain composition of amino acids in protein and bases in nucleotide. (chemicalbook.com)
  • example
  • An example of a spirocyclic compound is the photochromic switch spiropyran. (wikipedia.org)
  • For example, decalin is named bicyclo[4.4.ecane. (wikipedia.org)
  • The numbers are sometimes omitted when no ambiguity is created as there is no alternative possible - for example, bicyclo[1.1.utane is typically called simply bicyclobutane. (wikipedia.org)
  • effects
  • METHODS: We studied the effects of these compounds on whole-cell currents through cloned K(ATP) channels expressed in Xenopus oocytes or mammalian cells (HEK293). (ox.ac.uk)