• Clinical trials are medical research studies conducted on human subjects. (wikipedia.org)
  • The progress and results of clinical trials are analyzed statistically. (wikipedia.org)
  • Randomized clinical trials analyzed by the intention-to-treat (ITT) approach provide fair comparisons among the treatment groups because it avoids the bias associated with the non-random loss of the participants. (wikipedia.org)
  • However, the National Academy of Sciences, in an advisory report to the Food and Drug Administration on missing data in clinical trials, recommended against the uncritical use of methods like LOCF, stating that "Single imputation methods like last observation carried forward and baseline observation carried forward should not be used as the primary approach to the treatment of missing data unless the assumptions that underlie them are scientifically justified. (wikipedia.org)
  • As the 1998 International Conference on Harmonization E9 Guidance on Statisticial Principles for Clinical Trials noted, "Unfortunately, no universally applicable methods of handling missing values can be recommended. (wikipedia.org)
  • 10 Recommendations for hormone therapy, for example, were based on observational studies and were later challenged by prospective trials. (aafp.org)
  • To examine indicators of publication bias in randomised controlled trials of psychotherapy for adult depression. (cambridge.org)
  • Study I described a review of 58 clinical trials (CTs) of etoricoxib to assess its compliance with the Recommendations of Evaluation of Gender Differences in the Clinical Evaluation of Drugs. (nih.gov)
  • Randomised controlled trials (RCTs) are one of the least biassed sources of evidence and the cornerstone of evidence-based medicine, but involve relatively small numbers of highly selected patients who do not reflect the general IBD population (e.g. pregnant patients and patients with co-morbidities, extensive surgery and stomas of all types are excluded). (ecco-ibd.eu)
  • Remote monitoring and leveraging wearable devices and sensors in clinical trials. (iconplc.com)
  • However, since such therapeutics are relatively new, there are many aspects to these clinical trials that differ from trials for traditional therapeutics, and which sponsors will need to consider. (iconplc.com)
  • Students will distinguish descriptive epidemiology from ana epidemiology and they will then cover the key epidemiological study designs in a logical sequence from ecological and cross sectional studies to case-control and cohort studies, and randomized controlled trials. (uaeu.ac.ae)
  • They will then be introduced to screening and clinical trials. (uaeu.ac.ae)
  • The biosta session deal with the interpretation of results obtained from the practical applications of statistics used in medical research including cohort studies and clinical trials. (uaeu.ac.ae)
  • Randomized controlled trials, cohort studies, and case-control studies were eligible. (chiroindex.org)
  • A systematic literature search was conducted, using PubMed, EMBASE, PsycInfo, CINAHL and OpenGrey databases, to identify all studies which compared treatment-resistant schizophrenia (defined as either a lack of response to two antipsychotic trials or clozapine prescription) to treatment-responsive schizophrenia (defined as known response to non-clozapine antipsychotics). (biomedcentral.com)
  • The approaches tested must be based on widely accepted interventions previously demonstrated to be efficacious in clinical trials. (nih.gov)
  • A literature search was conducted for randomized controlled trials (RCTs) and observational studies of telehealth strategies for women's reproductive health and IPV versus usual care for the period July 2016 to May 2022. (ahrq.gov)
  • A bias in a systematic review caused by incompleteness of the search, such as omitting non-English language sources, or unpublished trials (inconclusive trials are less likely to be published than conclusive ones, but are not necessarily less valid). (nhsevidencetoolkit.net)
  • Quantitative research generates numerical data or data that can be converted into numbers, for example clinical trials or the National Census, which counts people and households. (nhsevidencetoolkit.net)
  • The review included 44 randomized clinical trials with more than 3000 participants using six herbal remedies: apple cider vinegar, cinnamon, curcumin, fenugreek seeds, ginger , and saffron. (medscape.com)
  • Apple cider vinegar, fenugreek seeds, curcumin (turmeric), and cinnamon resulted in statistically significant reductions in fasting blood glucose compared with the control groups in the clinical trials. (medscape.com)
  • Apple cider vinegar had three clinical trials to back the finding, and fenugreek seeds had four studies supporting the results - fewer than the other included remedies. (medscape.com)
  • The authors also identified risks of bias from the randomization process and the allocation concealment process in several of the included trials. (medscape.com)
  • The six herbal remedies included in the study were chosen out of dozens of popular complementary medicines for the strength and number of clinical trials backing their use. (medscape.com)
  • Study Selection: Two reviewers independently screened for parallel and crossover randomized clinical trials (RCTs) that compared, in patients with refractory or unexplained chronic cough, either gefapixant with placebo, or 2 or more doses of gefapixant with or without placebo. (bvsalud.org)
  • PGx data is also important for drug discovery, clinical trials, and development of clinical PGx tests. (cdc.gov)
  • In addition, lack of ethnic diversity in PGx data sets can widen health disparities by negatively affecting the outcomes of clinical drug trials and translating genetic research into clinical practice. (cdc.gov)
  • 65 mmHg in patients after cardiac arrest (CA). Recent trials have studied the effects of targeting a higher MAP as compared to a lower MAP after CA. We performed a systematic review and individual patient data meta-analysis to investigate the effects of higher versus lower MAP targets on patient outcome. (lu.se)
  • Results: Four eligible clinical trials were identified, randomizing a total of 1,087 patients. (lu.se)
  • All the included trials were assessed as having a low risk for bias. (lu.se)
  • This means that for clinicians reading POCUS studies, attention to the blinding practices is important to ensure the results are generalizable. (bmj.com)
  • The EHR Research Group at LSHTM comprises a wide range of epidemiologists, statisticians, and clinicians with extensive experience analysing real-world data from around the world. (lshtm.ac.uk)
  • Clinicians engage in critical self-exploration, in which they explore their own biases as therapists. (scv-camft.org)
  • In an era in which evidence-based medicine is being promoted, increasing direct health care costs need to be controlled and the subjective perception of health by patients is increasingly valued, epidemiological studies provide essential additional information to clinicians and health care organisations. (ecco-ibd.eu)
  • Pharmaco-epidemiological post-marketing studies are subsequently important to provide clinicians with additional information on real world effectiveness and safety. (ecco-ibd.eu)
  • Perhaps most clinicians would admit that confounding factors exist, but it is important to examine both the clinical and scientific implications. (psychiatrictimes.com)
  • Paul Yock presented interesting examples from Stanford's unique Biodesign fellowship , which brings clinicians together with engineers, scientists, and others to design novel solutions for the clinical needs in medicine. (jwatch.org)
  • As clinicians around the world seek research findings to help inform treatment decisions related to the pandemic, the importance of publishing the findings of well-designed research - whether the results are positive or negative - has been confirmed. (heart.org)
  • As an alternative to weighting in- practitioners and patient decisions use disorders, there has been consid- dividual studies, clinicians may draw about appropriate health care for spe- erable controversy about what con- upon published syntheses of study find- cific clinical circumstances" ( 7 ). (who.int)
  • Although most people probably bring their own inherent biases with them when they enter the healthcare workforce, it is also known that they may acquire biases along the way as a result of interactions with other clinicians, including during education and training. (medscape.com)
  • Could the electronic health record (EHR)-specifically, the notes written by clinicians about their patients-be another way in which clinicians may unwittingly transmit bias to each other? (medscape.com)
  • A diverse team capitalising on research opportunities offered by routinely collected data, bringing methodological rigour to provide real-world evidence for important questions regarding human health. (lshtm.ac.uk)
  • The overarching aim of the EHR Research Group is to capitalise on research opportunities offered by the availability of routinely collected data, bringing methodological rigour to provide real-world evidence for important questions regarding human health. (lshtm.ac.uk)
  • The methodological limitations of the published literature prevent definitive conclusions, and further research is needed to better understand the relationship between breastfeeding and mental health in mothers and children. (bvsalud.org)
  • In 2005, epidemiologist John Ioannidis analyzed published replications of highly cited articles in clinical research that presented either a higher level of methodological rigor or a higher sample size than the original articles. (bvsalud.org)
  • An article in American Family Physician summarizing the top 20 research studies of 2011 reported on a number of practical, patient-oriented findings. (aafp.org)
  • Dividing research findings into the smallest publishable units might increase an investigator's total number of publications, but works against the interests of science. (uaf.edu)
  • In the case of clinical findings, this could contribute to a false impression that some greater number of patients have been studied. (uaf.edu)
  • While taking credit for someone else's research findings is clearly a greater wrong than copying their methods section, both are examples of plagiarism-- taking personal credit for someone else's words or ideas. (uaf.edu)
  • One of the most consistent findings in autism research has been the male-to-female prevalence ratio of 4:1 (Nordgren et al. (autism.org)
  • Contrary to historical findings, contemporary studies calculate an autism gender/sex ratio of 3:1, and recent investigations reveal gender biases in many diagnostic tools and assessments. (autism.org)
  • Lack of clear criteria to classify frailty and reliance on subjective assessment introduces the risk for bias, threatens the validity and interpretation of findings, and hinders transferability of findings to other contexts. (hindawi.com)
  • Clear frailty inclusion and exclusion criteria and a standardized approach in the reporting of how frailty is conceptually and operationally defined in study abstracts and the methodology used is necessary to facilitate dissemination and development of metasynthesis studies that aggregate qualitative research findings that can be used to inform future research and applications in clinical practice to improve healthcare. (hindawi.com)
  • Re-using data from registries is becoming an integral component of medical research and could accelerate findings from research to practice. (epidemiologie.nl)
  • The problems include, but are not restricted to, failure to publish all research findings, inadequate sharing of study methodologies, and inconsistent disclosure of conflicts of interest. (bmj.com)
  • As profound biases in medical research continue to reward "positive," interesting, or novel findings, worthy sentiments are not enough. (bmj.com)
  • October 1, 2020― Together, The Center for Biomedical Research Transparency (CBMRT), the American Heart Association (AHA) and Wolters Kluwer continue to address the issue of publication bias - and the importance of publishing research with negative findings - by launching the Null Hypothesis Initiative for all of the AHA's 12 peer-reviewed, scientific research journals. (heart.org)
  • The drive to publish the Null Hypothesis collection is to raise the awareness of the importance of negative/full findings to the scientific community -information that can help to reduce publication bias and give way to future advancements. (heart.org)
  • The Null Hypothesis Initiative, which was first launched by CBMRT in 2017 with Neurology - the flagship journal of the American Academy of Neurology also published by Wolters Kluwer - has already demonstrated its potential to promote balance in academic publications by encouraging more authors to write up and submit important negative and inconclusive research findings for peer review. (heart.org)
  • CBMRT's partnership with the AHA seeks to expand the impact of this work by featuring the research work of authors from within the AHA's robust scientific portfolio who choose to share their research findings for the benefit of informing future research. (heart.org)
  • It is critical to ensure well-designed research with negative or null/inconclusive findings are catalogued and available to help inform and validate future research, discourse and clinical care. (heart.org)
  • Together we can address publication bias by encouraging the write-up and publication of all well-performed studies - including those with "negative"/null or inconclusive findings. (heart.org)
  • however, no individual gene-association study reported their findings surviving correction for multiple comparisons. (biomedcentral.com)
  • Conclusions These findings suggest an altered attentive bias towards pictures with a high degree of interpersonal communication information across different clinical phases in schizophrenia. (bmj.com)
  • Even with high-quality rigorous research designs, implementation, and analysis, the value of research for practice guidelines can be limited by decisions made during protocol design, study procedures, and dissemination of findings. (uspreventiveservicestaskforce.org)
  • Our findings highlight the need for further research examining drivers of for public health programming and the designing of appropriate obesity disparities among children in rural communities. (cdc.gov)
  • In recent years, data on the reproducibility of published findings in some areas of research has become available. (bvsalud.org)
  • Still, the available figures suggest that research findings, even if peer-reviewed and published in reputable journals, should not be necessarily assumed to be reproducible. (bvsalud.org)
  • This study aimed to assess the feasibility of recruiting and following up an e-cohort of adults born preterm worldwide and provide estimations of participation, characteristics of participants, the acceptability of questions, and the quality of data collected. (jmir.org)
  • The age of the study participants ranged from 50 to 75 years old (59.9 ± 7). (who.int)
  • Participants perceived that a multimodal online platform facilitated by clinical champions influences knowledge transfer, skills and behaviour, encourages workplace CPI activities. (biomedcentral.com)
  • Participants with expertise in the assessment and management of people with LSS were invited using an international distribution process used for two previous Delphi studies led by the Taskforce. (biomedcentral.com)
  • Of 397 study participants, 86% rated their agreement ≥ 4 for the proposed algorithm on a 0-6 scale, of which 22% completely agreed. (biomedcentral.com)
  • We selected 10 key terms related to practice research and asked participants whether they knew the meaning of. (scirp.org)
  • Additionally, the agreement among participants about presence or absence of specific biases was assessed. (bmj.com)
  • We included 40 studies with 908,032 participants. (cdc.gov)
  • Classic epidemiological research has shown that the incidence and prevalence of IBD have increased rapidly in recent decades [1]. (ecco-ibd.eu)
  • Population-based prevalence and incidence studies are essential for understanding the burden of frontotemporal dementia (FTD). (cambridge.org)
  • The report makes several recommendations to reduce the prevalence of diagnostic error, covering many aspects of healthcare, from research funding to legal liability to patient advocacy. (bmj.com)
  • 2005). Prevalence of mental disorders in AjzenI(1991).Thetheoryofplannedbehav- agnostic and Statistical Manual of Mental the Zurich Cohort Study: a twenty year ior. (who.int)
  • Finally, it recommended sensitivity analyses as part of clinical trial reporting to assess the sensitivity of the results to the assumptions about the missing data mechanism. (wikipedia.org)
  • In addition, more studies are needed to confirm the impact of potential factors and to assess training protocols among a large population of individuals living with HIV who are at risk of developing HAND. (natap.org)
  • ABSTRACT The purpose of this study was to develop a Persian version of ECOS-16 Questionnaire and assess its reliability and validity. (who.int)
  • Risk of bias was assessed using the Newcastle-Ottawa Scale (NOS) while grading of Recommendations Assessment, Development and Evaluation (GRADE) was used to assess the certainty of evidence. (bvsalud.org)
  • We used the Cochrane Risk of Bias tool, version 2 (RoB 2) to assess for risk of bias. (lu.se)
  • The assumption is that the patients improve gradually from the start of the study until the end, so that carrying forward an intermediate value is a conservative estimate of how well the person would have done had he or she remained in the study. (wikipedia.org)
  • Other studies show that using tight control in patients with diabetes mellitus has produced fewer benefits than previously thought, and long-term treatment with bisphosphonates does not reduce the risk of femoral neck fracture. (aafp.org)
  • Briefly, we identified all patients who had had CDAD (based on either clinical diagnosis or a positive toxin test result) from 1993 through 2004 and who were registered for ≥2 years in a general practice anywhere in the United Kingdom. (cdc.gov)
  • Each case-patient was matched by practice and age (±2 years) to 10 control-patients who also had not been hospitalized during the prior year. (cdc.gov)
  • These clinical markers are, however, present in a large proportion of patients and their discriminative accuracy is still limited. (ecco-ibd.eu)
  • Patients who were diagnosed as secondary osteoporosis by clinical and laboratory examinations were excluded. (who.int)
  • Yet aside from some researchers and patients who have tried to get answers for themselves, awareness of the crisis in research remains limited. (bmj.com)
  • Excluding the wider public from this debate is a wasted opportunity, since, as both funders of research and as patients, they have the biggest stake in rectifying these problems. (bmj.com)
  • Doing so not only improves research culture and enhances research efficiency but reduces the risk of avoidable harm to patients by ensuring that clinical practice is informed by a more complete and balanced record," said A/Professor Sandra Petty, CEO of CBMRT. (heart.org)
  • In recent years several studies have reported altered levels and activities of G-protein alpha subunits in depressive patients. (neurotransmitter.net)
  • The purpose of this study was to estimate decreases in 10-year atherosclerotic cardiovascular disease (ASCVD) risk associated with EvidenceNOW, an initiative spanning multiple states that sought to improve cardiovascular preventive care by providing supportive interventions such as practice facilitation to address the "ABCS": (A)spirin for high-risk patients, (B)lood pressure control for hypertensive people, (C)holesterol management, and (S)moking screening and cessation counseling. (ahrq.gov)
  • Methods This study included 78 persons at clinical high risk (CHR) for schizophrenia, 68 first-episode (FEZ) patients, and 39 chronically ill patients from the Shanghai At Risk for Psychosis Extending Project (SHARP Extending cohort) as well as 74 healthy controls (HCs). (bmj.com)
  • Qualitative research techniques such as focus groups and in-depth interviews have been used in one-off projects commissioned by guideline development groups to find out more about the views and experiences of patients and carers. (nhsevidencetoolkit.net)
  • A third indicator of bias is implying patients' responsibility for their own condition with references to them being uncooperative: for example, documentation that states "the patient is refusing his oxygen mask" versus a statement that "the patient is not tolerating the oxygen mask. (medscape.com)
  • Information from the United Kingdom Clinical Practice Research Datalink and the Hospital Episode Statistics database was analyzed for 28,110 patients who were newly prescribed tramadol and 305,924 individuals who were newly prescribed codeine, all for noncancer pain, with 11,019 controls also included in the study. (medscape.com)
  • Fourteen MIT doctoral students will work side-by-side with clinical experts from HHC to use artificial intelligence and machine learning to advance healthcare. (hartfordhealthcare.org)
  • She is passionate about healthcare applications, and much of her research has been inspired by collaborations with hospitals (including work with Hartford Hospital on predictive machine learning models for length of stay reduction and identification of life-threatening patient events) that aim to improve the quality of their services and operations. (hartfordhealthcare.org)
  • Lisa is a second-year doctoral student and her research integrates optimization and machine learning with applications in healthcare and special interest in prescription. (hartfordhealthcare.org)
  • Jiayi is a second-year doctoral student with research interests that center around the synergy of machine learning and optimization in healthcare applications. (hartfordhealthcare.org)
  • His research experience thusfar has been in predictive models and optimization, both in topics regarding healthcare. (hartfordhealthcare.org)
  • Striving for high reliability in healthcare: a qualitative study of the implementation of a hospital safety programme. (ahrq.gov)
  • Development of a multicomponent intervention to decrease racial bias among healthcare staff. (ahrq.gov)
  • Organizational characteristics and perceptions of clinical event notification services in healthcare settings: a study of health information exchange. (ahrq.gov)
  • Although frailty was generally defined as a multidimensional, biopsychosocial construct with loss of resilience and vulnerability to adverse outcomes, most studies defined the study population based on older age and physical impairments derived from subjective assessment by the researcher, a healthcare professional, or a family member. (hindawi.com)
  • The extent of that aggressiveness and its impact on healthcare costs warrant further studies. (bmj.com)
  • Registry-based studies could render real-world evidence to better inform clinical decision making and may have substantial impact on the delivery of healthcare and therapeutic management. (epidemiologie.nl)
  • With sparse and sometimes inconsistent evidence to guide clinical decision-making, variable clinical care may lead to unsatisfactory patient outcomes and inefficient use of healthcare resources. (biomedcentral.com)
  • There is a need to establish evidence-based practice to expand the field, as it is the only practice accepted by other healthcare practitioners. (scirp.org)
  • These researches became good evidence that community pharmacists can contribute to manage disease and promote healthcare system. (scirp.org)
  • One barrier to achieving change is that it is difficult to explain these complex problems, as they are not fully understood even by many in healthcare and research. (bmj.com)
  • Boston Strategic Partners, Inc. has an immediate opening for a 40+ hour/week, work-from-home Data Scientist to assist with research using Electronic Health Records (EHR) and other healthcare-related data. (bostonsp.com)
  • Founded in 2003, Boston Strategic Partners, Inc. is an exclusively healthcare-focused consulting firm with a team of experienced clinical/medical, business, and programming professionals. (bostonsp.com)
  • Implicit bias is a well-recognized contributor to the ongoing dilemma of healthcare disparities. (medscape.com)
  • The TRANSLATE CKD study is an ongoing national, mixed-methods, cluster randomized control trial that examines the implementation of evidence-based guidelines for CKD into primary care practice. (jabfm.org)
  • As part of the mixed-methods process evaluation, semistructured interviews were conducted by phone with 27 providers participating in the study. (jabfm.org)
  • We have particular interest in developing and applying optimal research methods, including both observational and interventional approaches. (lshtm.ac.uk)
  • 2021). While these and other theories have been widely assessed, study methods and data collection vary across experiments making corroborated evidence rare and increasing the potential for errors in analysis (Zhang et al. (autism.org)
  • Data collection involved extracting the definition of frailty from the study aim, background, literature review, methods, and sampling strategy in each research study. (hindawi.com)
  • For the correct interpretation of these studies, basic knowledge of pharmaco-epidemiological methods is, however, important [9]. (ecco-ibd.eu)
  • advice on methods to reduce bias. (bostonsp.com)
  • Qualitative research or methodology does not try to quantify anything or use statistical methods - it's not about counting, but about words and their meaning. (nhsevidencetoolkit.net)
  • The clinical features range from Methods asymptomatic infection to severe pneumonia and death. (cdc.gov)
  • As both methods can quickly rank a large volume of pathogens, they generate an initial qualitative can be used to provide a short list for risk ranking using a more ranking for further study algorithm comprehensive technique. (who.int)
  • 15 Studies can also raise questions about harms associated with technology (such as radiation exposure from computed tomography) and testing (such as the harms of interventions initiated based on prostate-specific antigen testing exceeding the benefits of this testing). (aafp.org)
  • Differences in medication reconciliation interventions between six hospitals: a mixed method study. (ahrq.gov)
  • Future studies are needed to clarify whether there is a difference in training benefits between CCT programs and to examine the synergistic factors and outcomes of different auxiliary interventions (eg, tDCS or exercise). (natap.org)
  • A previous consensus conference on frailty endorsed the usefulness of defining frailty in clinical settings and the need for a clear conceptual framework, indicating that frailty was a clinical syndrome associated with increased vulnerability and potential for preventing, delaying, or reversing frailty with interventions [ 5 ]. (hindawi.com)
  • The interventions proposed under this FOA should have the potential to be widely disseminated to clinical practice, individuals and communities at risk. (nih.gov)
  • The USPSTF's evaluation of behavioral counseling interventions asks 2 primary questions: do interventions in the clinical setting influence persons to change their behavior, and does changing health behavior improve health outcomes with minimal harms? (uspreventiveservicestaskforce.org)
  • Advances in implementation science, which focuses on adoption and implementation of evidence-based interventions, further enhance our ability to move along the continuum from research to practice recommendations to practice changes. (uspreventiveservicestaskforce.org)
  • Despite advances in the development of evidence-based behavioral counseling interventions, challenges remain in aggregating the research into recommendations for practice. (uspreventiveservicestaskforce.org)
  • Figure 1 ) The systematic evidence reviews done for the USPSTF seek intervention studies that can answer whether interventions lead to changes in health outcomes and whether they can be implemented in primary care to effect behavior change. (uspreventiveservicestaskforce.org)
  • The WHO Mental Health Gap Action Programme intervention guide offers the most well synthesized summary of interventions that have evidence of support, clinical acceptance, extensive implementation and expert consensus. (who.int)
  • La présente note d'orientation a pour objectif de passer en revue les interventions disponibles pour la prise en charge des troubles liés à la consommation de substances psychoactives, d'examiner les bases factuelles pour ces interventions dont le guide d'intervention du Programme d'action de l'OMS : Combler les lacunes en santé mentale (mhGAP), et d'effectuer des recommandations concernant le traitement de ces troubles. (who.int)
  • Hospital-based medication reconciliation practices: a systematic review. (ahrq.gov)
  • Implicit racial/ethnic bias among health care professionals and its influence on health care outcomes: a systematic review. (ahrq.gov)
  • Systematic review of the impact of physician implicit racial bias on clinical decision making. (ahrq.gov)
  • The purpose of this qualitative systematic review was to examine how frailty was conceptually and operationally defined for participant inclusion in qualitative research focused on the lived experience of frailty in community-living frail older adults. (hindawi.com)
  • While some observational studies have explored the relationship between breastfeeding and mental health outcomes in mothers and children, a systematic review of the available evidence is lacking. (bvsalud.org)
  • Results Among the 150 articles identified, 42 were retained for review: 1 clinical trial, 3 observational cohorts, 21 retrospective analyses and 17 administrative data-based studies. (bmj.com)
  • Many thoughtful and constructive analyses focus on the importance of several factors in the design and conduct of studies. (uspreventiveservicestaskforce.org)
  • This leads to a literature that is full of positive and impacting results, but usually at the expense of selective or biased analyses and inflated effects, which distort our perception of the scientific problems under study (16). (bvsalud.org)
  • We studied the frequency of carbapenemase-producing (CP) CRE and performed whole-genome sequencing analyses of all carbapenem-resistant (CR) Klebsiella pneumoniae (CRKpn) isolates collected during the study period. (cdc.gov)
  • Effects of a refined evidence-based toolkit and mentored implementation on medication reconciliation at 18 hospitals: results of the MARQUIS2 study. (ahrq.gov)
  • In Study III, the websites of the eight best-selling hormone replacement therapy drugs in Spain on Google first page of results were analysed. (nih.gov)
  • Our results revealed no publication bias. (natap.org)
  • We selected 10 key terms commonly used to structure clinical questions, establish study designs, and evaluate results in practice research. (scirp.org)
  • Results of studies of proposed causes and treatments are often poor or contradictory. (wikipedia.org)
  • The results present challenges for current error reduction strategies based on identification of cognitive biases. (bmj.com)
  • The importance of publishing research with negative results has been highlighted recently in the example of hydroxychloroquine as a treatment for novel coronavirus 2019 (COVID-19). (heart.org)
  • We encourage and support the publication of negative study results and see the Null Hypothesis as a positive step to help authors achieve this goal for more balanced research," said Jayne Marks, VP, Publishing, Health Learning, Research & Practice, Wolters Kluwer. (heart.org)
  • The results of this study suggest that the investigated G-protein beta3 subunit seems to be a susceptibility factor for major depression and maybe even for bipolar disorder, but not for schizophrenia. (neurotransmitter.net)
  • The results are assessed by rigorous comparison of rates of disease, death, recovery or other appropriate outcomes in the study and control groups. (nhsevidencetoolkit.net)
  • RESULTS: Our review identified twenty-one original study. (bvsalud.org)
  • The results of this study could be used to promote the uptake of clinical PGx testing to enhance precision medicine, especially in underrepresented populations. (cdc.gov)
  • The results indicated that the selected studies used the qualitative method, are national and come from empirical research, clinical practice and theorists. (bvsalud.org)
  • Studies have correlated the outcomes of physician-supervised oral food challenges with serum test results. (medscape.com)
  • In 2015, the results of a large systematic replication of studies in cognitive and social psychology were released, which indicated success rates between 36% and 47% (9). (bvsalud.org)
  • This creates a problematic conflict of interest for the authors, as career advancement depends on obtaining particular results, biasing the conduct and the analysis of studies (17). (bvsalud.org)
  • Although they are viewed as such in basic science descriptions, the extrapolation into human studies has not been critically assessed (Hines, 2019). (autism.org)
  • Search of six electronic databases, 1994-2019, yielded 25 studies. (hindawi.com)
  • Implementation strategies in the context of medication reconciliation: a qualitative study. (ahrq.gov)
  • Studies in the field of implementation science are especially needed to address the challenge of removing barriers and bringing CCT from scientific research into clinical practice and implementing CCT programs in the real world. (natap.org)
  • Future studies are needed to design optimal specific training programs and use implementation science to enable the transformation of CCT from a scientific research tool to a real-world clinical intervention. (natap.org)
  • Late phase research, technology solutions and access to RWD are at the forefront of creating efficiencies in all stages of study design and implementation. (iconplc.com)
  • The second cluster was added into the 2015-2016 exit-surveys to measure clinical practice improvement (CPI) activities implementation ( N = 520). (biomedcentral.com)
  • In addition to publishing research reports and reviews, JAPA publishes articles that examine the development, implementation, and evaluation of physical activity programs among older adults. (humankinetics.com)
  • 11. With a clear remit to generate practical guidance for Member States, the communications workstream has focused on contemporary best practice thinking and campaign implementation to populate its guidance. (who.int)
  • Clinical heterogeneity in the frequency of flares and the appearance of complications and extra-intestinal manifestations is one of the main features of IBD. (ecco-ibd.eu)
  • Schizophrenia is highly heterogeneous and better characterisation of this heterogeneity is needed to progress research into aetiology, mechanisms and treatment. (biomedcentral.com)
  • Study heterogeneity was assessed using the I2 statistic. (bvsalud.org)
  • Publication bias and heterogeneity were examined. (lu.se)
  • ES for pain relief from IA hyaluronic acid, glucosamine sulphate, chondroitin sulphate and avocado soybean unsponifiables also diminished and there was greater heterogeneity of outcomes and more evidence of publication bias. (lu.se)
  • This thesis is part of the studies of gender bias in health which together with the paradigm of evidence-based medicine shares the empirical assumption that there are inaccuracies in medical practice, in addition to a lack of rigour and transparency. (nih.gov)
  • Unfortunately, however, empirical studies investigating the relationships between various regulatory rules and practices and consumer safety and workforce equity are rare in the existing literature. (journaltocs.ac.uk)
  • This paper identifies critical gaps in the current knowledge base and proposes a series of future research agendas that call for empirical evidence, including detailed data on jurisdictional regulatory rules and practices, the measures of consumer safety, and licensed social workers' demographic, employment, and practice characteristics. (journaltocs.ac.uk)
  • The paper concludes by calling out to all social work stakeholders about the need for empirical evidence on the effects of social work regulatory rules and practices. (journaltocs.ac.uk)
  • Empirical research is needed to thoroughly understand the interplay between HCW risk perceptions of distinct AGPs, their affective responses to conducting these procedures under various conditions, and their resulting decision to participate in these procedures. (cdc.gov)
  • These include the UK Clinical Practice Research Datalink (CPRD) based on primary care records, Hospital Episode Statistics, administrative data, drug and disease registries, and numerous international data sources. (lshtm.ac.uk)
  • If you are not a member of the EHR Research Group at LSHTM and are planning to use CPRD data, please refer to the Clinical Practice Research Datalink website for further details. (lshtm.ac.uk)
  • We are inviting entrepreneurs from across the world to evaluate proposed new technologies and products with our clinical experts. (hartfordhealthcare.org)
  • Because inpatients are often exposed to multiple antimicrobial drugs, these studies may have limited ability to evaluate agents rarely prescribed or rarely prescribed alone (e.g., macrolides). (cdc.gov)
  • Our original research uncovers how US payer organizations currently evaluate and manage digital therapeutics, and their perspectives for the future. (iconplc.com)
  • This study was undertaken to evaluate the literature on aggressive inpatient EOL care for lung cancer and analyse the evolution of its aggressiveness over time. (bmj.com)
  • They recommended that future research should evaluate clinical outcomes associated with more comprehensive insurance coverage. (ahrq.gov)
  • The purpose of this study is to systematically evaluate the association between breastfeeding and mental health disorders in mothers and children. (bvsalud.org)
  • For example, declining effect size when studies are replicated has been attributed to both publication bias and unconscious errors in data interpretation. (aafp.org)
  • It is not clear whether the effects of cognitive-behavioural therapy and other psychotherapies have been overestimated because of publication bias. (cambridge.org)
  • As indicators of publication bias we examined funnel plots, calculated adjusted effect sizes after publication had been taken into account using Duval & Tweedie's procedure, and tested the symmetry of the funnel plots using the Begg & Mazumdar rank correlation test and Egger's test. (cambridge.org)
  • The mean effect size was 0.67, which was reduced after adjustment for publication bias to 0.42 (51 imputed studies). (cambridge.org)
  • The effects of psychotherapy for adult depression seem to be overestimated considerably because of publication bias. (cambridge.org)
  • Reference Cuijpers, van Straten, van Oppen and Andersson 6 It may be possible, however, that these effects are overestimated because of publication bias - the tendency for increased publication rates among studies that show a statistically significant effect of treatment. (cambridge.org)
  • Reference Rothstein, Sutton and Borenstein 7 , Reference Sterne, Egger, Rothstein, Sutton and Borenstein 8 Publication bias can be considered as one of the major drawbacks of meta-analytic studies and a threat to their validity. (cambridge.org)
  • Although many meta-analytic studies have examined the effects of cognitive-behavioural and other psychotherapies for depression, Reference Cuijpers and Dekker 11 publication bias has not been examined thoroughly in these studies. (cambridge.org)
  • Indeed, publication is central to many disputes about responsible conduct of research. (uaf.edu)
  • For these latter reasons, publication has a prominent role in advancement, promotion, and continued research funding. (uaf.edu)
  • Ultimately, the centrality of publication in academic life means that it is implicated to some degree in nearly all aspects of the responsible conduct of research. (uaf.edu)
  • Without such reference, the second publication constitutes a falsification of the research record. (uaf.edu)
  • Chair of the AHA's Scientific Publishing Committee N. A. Mark Estes, III, M.D., commented, "The American Heart Association's scientific journals are committed to changing and strengthening research culture as it relates to publication bias, and this new Null Hypothesis collection allows us to ensure that we strive for balance. (heart.org)
  • Conclusion: Publication of a large amount of new research evidence has resulted in changes in the calculated risk-benefit ratio for some treatments for OA. (lu.se)
  • 6 Other Issues 27 Overview 249 28 Vote Counting a New Name for an Old Problem 251 29 Power Analysis for Meta-Analysis 257 30 Publication Bias 277 Pt. (who.int)
  • If this is so, then physicians already familiar with common cognitive biases should consistently identify biases present in a clinical workup. (bmj.com)
  • The aim of this paper is to determine whether physicians agree on the presence or absence of particular biases in a clinical case workup and how case outcome knowledge affects bias identification. (bmj.com)
  • Multicentre cohort study of 16-70-year-olds admitted to 4 UK hospitals following injury. (springer.com)
  • Evidence of such bias has been found in many intervention fields, including that of depression treatment. (cambridge.org)
  • An epidemiological experiment in which subjects in a population are randomly allocated into groups, usually called study and control groups, to receive or not receive an experimental preventive or therapeutic procedure, manoeuvre or intervention. (nhsevidencetoolkit.net)
  • The challenges relate broadly to study populations, intervention protocols, assessment of outcomes, and linking behavior changes to health outcomes. (uspreventiveservicestaskforce.org)
  • 5-7 These factors relate to study populations, practice settings, and intervention protocols and components. (uspreventiveservicestaskforce.org)
  • 8 This section focuses on challenges related to study populations, intervention protocols, outcomes and assessment, and linking behavior changes to health outcomes. (uspreventiveservicestaskforce.org)
  • intervention guide, and make recom- concept, to date, uniformly acknowl- Clinical expertise mendations related to the treatment of edge a variety of sources from which substance use disorders. (who.int)
  • Interpretation Individual physicians are unable to agree on the presence or absence of individual cognitive biases. (bmj.com)
  • The aim of this study was therefore to demonstrate the impact of psychological morbidity one month post-injury on subsequent quality of life in a general injury population in the UK to inform development of trauma care and rehabilitation services. (springer.com)
  • It may, however, serve as a clinical guide until evidence is sufficient to inform a fully stratified care model. (biomedcentral.com)
  • These data are critical to inform national policies and clinical care. (cdc.gov)
  • We further analyzed data from a population-based case-control study that was constructed using the United Kingdom's General Practice Research Database (GPRD). (cdc.gov)
  • GPRD is a well-validated ( 7 ) clinical database that records information taken from general practice records. (cdc.gov)
  • The limited number included in the review is a drawback, according to Merlin Willcox, DPhil, a clinical lecturer in general practice at the University of Southampton, United Kingdom, who was not involved in the research. (medscape.com)
  • Epidemiology is data driven and to avoid bias and guarantee validity, systematic data collection, meticulous study design and careful selection of the population and method of analysis are crucial. (ecco-ibd.eu)
  • 8-10 These recommendations emphasize the importance of the external validity of the research base, best summarized by the adage, "If you want to get research into practice, you must get practice into research. (uspreventiveservicestaskforce.org)
  • Eight RCTs, 1 nonrandomized trial, and 7 observational studies were included (7 studies of contraceptive care and 9 of IPV services). (ahrq.gov)
  • How can epidemiology help in clinical practice? (ecco-ibd.eu)
  • They will learn more about ethics in medical research and will have a revision session on scientific writin They will have sessions on chronic disease and injury epidemiology and will conclude with environmental epidemiology and an infectious disease case study. (uaeu.ac.ae)
  • ABSTRACT For the past 50 years, there has been a systematic effort to expand and improve treatment services for individuals with substance use disorders by developing an evidence base to guide practice. (who.int)
  • The primary outcome variable (Investigator's Global Assessment of Acne) was assessed by investigators blinded to randomisation throughout the study period. (bmj.com)
  • After a revision session covering he outcome measures, students will cover rate adjustment, cause, bias and confounding. (uaeu.ac.ae)
  • Inter-observer agreement was the primary outcome for the study. (gi.org)
  • We compared the number of biases identified when the outcome implied a correct or incorrect primary diagnosis. (bmj.com)
  • when the outcome implies a diagnostic error, twice as many biases are identified. (bmj.com)
  • Future research is needed to examine the effectiveness of multimodal care and guide clinical practice. (chiroindex.org)
  • Objective: To update evidence for available therapies in the treatment of hip and knee osteoarthritis (OA) and to examine whether research evidence has changed from 31 January 2006 to 31 January 2009. (lu.se)
  • Implicit racial bias, health care provider attitudes, and perceptions of health care quality among African American college students in Georgia, USA. (ahrq.gov)
  • Implicit racial bias in pediatric orthopaedic surgery. (ahrq.gov)
  • Implicit bias and caring for diverse populations: pediatric trainee attitudes and gaps in training. (ahrq.gov)
  • It is plausible that varying degrees of response to antipsychotics reflect categorically distinct illness subtypes, which would have significant implications for research and clinical practice. (biomedcentral.com)
  • What are the implications for public health practice? (cdc.gov)
  • To discuss the study and its implications, [ 1 ] Medscape spoke with Goddu and Mary Catherine Beach, MD, MPH, a professor of medicine in the School of Medicine at Johns Hopkins University and the principal investigator. (medscape.com)
  • In our study "Blinding practices during acute point-of-care ultrasound research: the BLIND-US meta-research study" (bmjebm-2020-111577), we searched the acute POCUS literature for studies assessing the diagnostic accuracy of POCUS. (bmj.com)
  • Most meta-analytic studies of cognitive-behavioural and other psychotherapies for adult depression have found that these therapies have moderate to large effects on depression compared with control conditions, Reference Cuijpers, van Straten, Warmerdam and Smits 1 - Reference McDermut, Miller and Brown 5 effects that are comparable to those of antidepressive medication. (cambridge.org)
  • Multiple studies involving cognitively healthy adults57 and individuals with Alzheimer disease62 have reported that training benefits extended beyond the cognitive domains assessed after training to include other cognitive domains, and these benefits have transferred to daily function, psychological health, and other higher-order competencies.63,64 We also found an association between CCT and daily function among people living with HIV. (natap.org)
  • Background Many authors have implicated cognitive biases as a primary cause of diagnostic error. (bmj.com)
  • 2 One chapter is devoted to summarising research on the psychology of clinical reasoning, described by a 'dual process' theory 2 , 3 in which two very different cognitive processes are at play: system 1, which is rapid, subconscious and relies heavily on cognitive shortcuts or 'heuristics' which may lead to a bias, and system 2, which is slow, conscious and analytical. (bmj.com)
  • While errors may arise in both systems, it is presumed that most errors arise from cognitive biases. (bmj.com)
  • The notion that cognitive biases are a primary cause of diagnostic error has been prevalent in the medical literature for over 30 years. (bmj.com)
  • The Original Research section contains scientific studies and investigations, systematic clinical observations, and controlled case studies. (humankinetics.com)
  • Evidence-based imental investigations, correlational into clinical practice are practice guide- practices studies, field studies, case reports and lines and best practices. (who.int)
  • One aspect of diagnostic accuracy study design that may impact generalizability and risk of bias are blinding practices. (bmj.com)
  • Studies investigating treatment strategies or aiming at head-to-head comparison of already available drugs are much less likely to be performed. (ecco-ibd.eu)
  • These studies help to provide information on the potential place of new drugs or strategies in the treatment of IBD. (ecco-ibd.eu)
  • AHRQ Projects funded by the Patient-Centered Outcomes Research Trust Fund. (ahrq.gov)
  • We serve all life science sectors including pharmaceuticals, biotech, medical devices, clinical diagnostics, and bioinformatics in five practice areas: Business & Clinical Strategy, Health Economics & Outcomes Research, Medical & Technical Communications, Regulatory Strategy, and Financial Advisory. (bostonsp.com)
  • 0000-0002-2119-3935 older age groups and higher levels of education, and with a comorbidity presented a total score of the highest level of covid-19 prevention practices. (bvsalud.org)
  • What is the autism gender bias? (autism.org)
  • Outside of genetics, explanations for the autism gender bias have included the Extreme Male Brain Theory (EMBT) and camouflaging. (autism.org)
  • This paper aims to identify whether health care staff perceive a 12-week online facilitated, multimodal, person-centred care, dementia education program influences their knowledge, skills, behaviour and practice improvement activities in dementia care. (biomedcentral.com)
  • Aims This pilot study used eye-tracking technology to investigate attentive bias towards interpersonal communication information across different clinical phases of schizophrenia. (bmj.com)
  • This policy brief aims to review the avail- ed that the definition of "best research are conducted. (who.int)
  • 9 Despite this, numerous studies have documented that primary care physicians' understanding, awareness, and adequate management of early CKD are lacking, and CKD is generally under-recognized and undertreated by primary care physicians. (jabfm.org)
  • Increase personal self-awareness of biases that may impact one's clinical practice with socially and culturally diverse communities. (scv-camft.org)
  • She holds a Ph.D. in American Studies, an M.A. in Counseling Psychology, a B.A. in African American Studies, and another B.A. in International Relations. (scv-camft.org)
  • To reduce bias, titles and abstracts were screened for eligibility by 2 independent reviewers. (cdc.gov)
  • However, medical investigators often have difficulties in accepting ITT analysis because of clinical trial issues like missing data or adherence to protocol. (wikipedia.org)
  • If a patient drops out of the study after the third week, then this value is "carried forward" and assumed to be his or her score for the 5 missing data points. (wikipedia.org)
  • The student-physician teams, under the direction of Professor Dimitris Bertsimas , will study how AI and ML can be used to predict disease probability sooner, provide more exacting tests and use massive amounts of data to deliver care that is more personalized. (hartfordhealthcare.org)
  • She holds a bachelor's degree in industrial engineering and global health studies from Northwestern University, and is particularly interested in using holistic, data-driven approaches to address public health challenges. (hartfordhealthcare.org)
  • Here is Liam Smeeth talking about why access to routinely collected health data is so important for the research community. (lshtm.ac.uk)
  • CPRD data can be accessed and used for studies by LSHTM staff. (lshtm.ac.uk)
  • Artificial intelligence (AI) technology, combined with big data, hold the potential to solve many key clinical trial challenges. (iconplc.com)
  • However, registry-based research also has risks, as data is not collected for the purpose of research, which may hamper data quality and introduce bias. (epidemiologie.nl)
  • All data relevant to the study are included in the article or uploaded as supplementary information. (bmj.com)
  • and use of existing data sets to link behavior change and clinical outcomes. (uspreventiveservicestaskforce.org)
  • data can be brought to bear on clinical Two other broad categories of docu- decision-making. (who.int)
  • In this chapter, we will use "reproducibility" and "replicability" interchangeably, indicating that a similar result is obtained when collecting new data under conditions similar to those in the original study. (bvsalud.org)
  • Of 51 treatment modalities, new data on efficacy have been published for more than half (26/39, 67%) of those for which research evidence was available in 2006. (lu.se)
  • 5 Complex Data Structures 22 Overview 215 23 Independent Subgroups within a Study 217 24 Multiple Outcomes or Time-Points Within a Study 225 25 Multiple Comparisons within a Study 239 26 Notes on Complex Data Structures 243 Pt. (who.int)
  • Subsequent to recommendations, follow-up studies raise questions about adverse effects of medications, such as the potentially deleterious cardiovascular effects of calcium supplementation. (aafp.org)
  • Disclosing adverse events in clinical practice: the delicate act of being open. (ahrq.gov)
  • Adverse events in women giving birth in a labor ward: a retrospective record review study. (ahrq.gov)
  • Cohort studies can also identify specific patient subgroups and clinical markers predictive of the risk of adverse effects or primary non-response, thereby facilitating personalised medicine approaches. (ecco-ibd.eu)
  • Our literature review indicated that chronic liver disease (CLD) is associ- ated with increased adverse clinical outcomes in terms of severity of dis- tality. (cdc.gov)
  • Describe the uses and limitations of different types of epidemiological studies and their applications to public health. (uaeu.ac.ae)
  • 42 Code of Federal Regulations, Chapter IV, §410.74 Physician assistants' services, §410.75 Nurse practitioners' services and §410.76 Clinical nurse specialists' services. (cms.gov)
  • Nevertheless, I think each practicing physician, should make efforts to incorporate social media as a routine part of clinical practice. (jwatch.org)
  • As the evidence supporting its integration into clinical practice grows, a critical look at research practices is important to ensure decisions are being made with the highest quality evidence possible. (bmj.com)
  • Implementing established evidence-based guidelines for CKD in practice has proven challenging for multiple reasons. (jabfm.org)
  • Two Dutch studies formed the foundation and the best available evidence for the practice of youth medical gender transition. (nih.gov)
  • Gender biases identified in this thesis limited the legitimacy of medicine, which is not based on the best possible evidence. (nih.gov)
  • Because of the evidence-based nature of DTx, in many cases a clinical trial is required to demonstrate safety and efficacy. (iconplc.com)
  • There is a widely-recognised need for standardised and evidence-based clinical practice guidelines [ 5 , 6 ] but current guidelines are inconsistent and rely on limited evidence [ 7 ]. (biomedcentral.com)
  • Studies with a low risk of bias were synthesized following best evidence synthesis principles. (chiroindex.org)
  • For depressive disorders (5 studies) and anxiety disorders (3 studies), we found conflicting evidence with some studies showing a small protective effect while others found no effect. (bvsalud.org)
  • Part III : Changes in evidence following systematic cumulative update of research published through January 2009. (lu.se)
  • Regular updating of research evidence can help to guide best clinical practice. (lu.se)
  • Early evidence on the efectivenes smoking regulations and at itudes towards consent in scho l-based survey research. (who.int)
  • The USPSTF relies on clear definitions of the populations that were studied to make recommendations for asymptomatic persons and to stratify recommendations for those who are at average or high risk for particular conditions (such as cardiovascular disease). (uspreventiveservicestaskforce.org)
  • In addition, databases that aggregate allele frequencies, such as gnomAD are also biased toward European populations and contain very little information from individuals of African or other ancestries. (cdc.gov)
  • Even so, a scientist's reputation is likely to be more respected if based on a few widely respected studies rather than on many small, fragmentary reports. (uaf.edu)
  • estimates of incidence vary widely because studies have used different definitions. (wikipedia.org)
  • Several problems with health research are now widely recognised. (bmj.com)
  • Whereas blinding of the POCUS interpreter to the reference stands (and vice versa) is as an important step to limit bias, whether the person performing the POCUS scan should be blinded to the patient's clinical information is less clear. (bmj.com)
  • Despite a proliferation of frailty frameworks and some agreement on aspects of physical frailty, the precise defining characteristics and clinical indicators for frailty and how to measure them in diverse care contexts (e.g., community, nursing home, and acute care hospital) are still evolving [ 2 , 4 ]. (hindawi.com)
  • Student is also expected to prepare a concise and complete Research Proposal that clearly defines the research problem and objectives, and outlines the research methodology and a plan that the student will follow for the dissertation work. (uaeu.ac.ae)
  • Our work covers a broad spectrum including disease aetiology, safety and effectiveness of medications, vaccines and surgery, environmental influences, and health services research. (lshtm.ac.uk)
  • These include the Wellcome Trust, Medical Research Council, National Institute for Health Research, GSK, and the British Heart Foundation. (lshtm.ac.uk)
  • Dr. Worsley combines her academic passion for exploring social identity issues with her clinical expertise in addressing the mental health needs of culturally diverse communities. (scv-camft.org)
  • Her vocational goal is to help eradicate mental health disparities that impair the health and well-being of communities of color as she continues to provide therapy services through her private practice in Northern California. (scv-camft.org)
  • They will learn how to ask public health research questions, propose hypotheses and select appropriate study designs. (uaeu.ac.ae)
  • In health care, qualitative techniques have been commonly used in research documenting the experience of chronic illness and in studies about the functioning of organisations. (nhsevidencetoolkit.net)
  • The inclusion criteria consisted of all studies evaluating links between breastfeeding and development of mental health disorders in children and mothers. (bvsalud.org)
  • Three studies evaluated the associations between breastfeeding and maternal mental health disorders. (bvsalud.org)
  • Three studies looking at association between breastfeeding and maternal mental health, were too heterogeneous to draw any firm conclusions. (bvsalud.org)
  • Beyond the communications working group, the workstream reached out to the broader professional communications community working in Member States, academia and analogous areas of public health, to build a contemporary picture of best practice in communications before developing and testing a bespoke approach to guidance on substandard and falsified medical products. (who.int)
  • Despite high levels of need, mental health is a relatively neglected area in Health EDRM, with little focus on services funding, human resources or research in the field (6-7). (who.int)
  • Consequently, there is tremendous opportunity to improve disaster mental health risk reduction through rigorous research and informed policy. (who.int)
  • Thus, targeted and wel -timed research is required to reliably demonstrate the mental health impacts of disasters. (who.int)
  • Random pairs of independent reviewers screened studies for relevance and critically appraised relevant studies using the Scottish Intercollegiate Guidelines Network criteria. (chiroindex.org)
  • The purpose of our review was to investigate the effectiveness of multimodal care for the management of musculoskeletal disorders of the elbow, forearm, wrist and hand on self-rated recovery, functional recovery, or clinical outcomes in adults or children. (chiroindex.org)
  • Our search did not identify any low risk of bias studies examining the effectiveness of multimodal care for the management of other musculoskeletal disorders of the elbow, forearm, wrist or hand. (chiroindex.org)
  • 1 One striking feature of this article is the inclusion of several studies that challenge traditional medical opinion. (aafp.org)
  • We identified 97 studies meeting the inclusion criteria. (bmj.com)
  • Nineteen studies of moderate quality met inclusion criteria. (biomedcentral.com)
  • Allele frequencies will also be correlated with prescription drug use among the different ethnic groups to study whether drugs prescribed for each are appropriate given the PGx allele frequency determined for the population and how the drugs prescribed could be modified if more comprehensive PGx testing were available. (cdc.gov)
  • These efforts can directly improve patient care by helping to avoid repeating studies that won't work, and, therefore, accelerate new treatments. (heart.org)
  • Clinical recommendations may be more vulnerable to reversal when research conditions favor bias and error. (aafp.org)
  • Research must target the prevention or reversal of obesity, prevention of type 2 diabetes, improved care of type 1 and type 2 diabetes, or the prevention or delay of the complications of these conditions. (nih.gov)