• A key step during the initial phase of this process is the establishment of so-called proneural clusters in the Drosophila neuroectoderm, which are characterised by expression of proneural genes that belong to the basic helix-loop-helix (bHLH) family of transcriptional activators ( Dambly-Chaudiere and Vervoort, 1998 ). (silverchair.com)
  • Among 4,180 transcripts that changed significantly during development, approximately 2/3 of the genes were expressed at high levels up until PN5 and then declined whereas the other 1/3 of the genes increased expression from PN5 and remained at the higher levels until at least PN21. (biomedcentral.com)
  • This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. (en-academic.com)
  • 2. A gene network downstream of transcription factor Math5 regulates retinal progenitor cell competence and ganglion cell fate. (nih.gov)
  • The SRY gene encodes the testis determining factor , which is also referred to as the SRY protein . (wikidoc.org)
  • This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. (wikidoc.org)