OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, AgricultureHealth Care
BetaineLipotropic AgentsFertility Agents, MaleBetaine-Homocysteine S-MethyltransferaseSarcosineDietary SupplementsHomocysteineMethionineFolic AcidCholineFood, FortifiedAnimal FeedDouble-Blind MethodOsmotic PressureWater-Electrolyte BalanceDietVitaminsTime FactorsMuscle StrengthTensile StrengthHand StrengthShear StrengthBody WeightBeta vulgarisBetalainsBeveragesFood Coloring AgentsMenu PlanningNitratesPotassium Compounds
Choline supplementationKnown as trimethylglycineTrimethylglycineAnhydrousPlaceboDetermine if betaineBenefits of betaineEvidence that betaineHydrochlorideRepetitions performedVitamin C supplementationNatural betaineShow that supplementationMethionineHomocysteine levelsErgogenic1.25Hydrochloric acidCreatine monohydrateDietaryGramsDonorMethyl donorsMetabolicFetal growthIntakeCurcuminNutrient foundEfficacyPositivelyResearchersBeta AlanineStudy investigatedMetabolismSupplementEnduranceSupplements on the marketPepsinLiverSquatDigestionEffectsOutcomesAminoHistidineVitamins0.05Body compositionAbsorptionNutrientsSignificantly greaterConcentrationsIntracellularMiceEffect
Choline supplementation9
  • Previous studies show that maternal choline supplementation normalizes fetal growth and adiposity of progeny from obese mice. (cuny.edu)
  • Although we previously reported that maternal choline supplementation downregulated mRNA expression of genes involved in de novo lipogenesis in fetal livers, such alterations were not observed with BS, suggesting differential effects of betaine and choline on fetal gene expression. (cuny.edu)
  • Remarkably, the beneficial effects of choline supplementation appear to be transgenerational, not only protecting mice receiving choline supplementation during gestation and lactation, but also the subsequent offspring of these mice. (azbio.org)
  • While this second generation received no direct choline supplementation, they nevertheless reaped the benefits of treatment, likely due to inherited modifications in their genes. (azbio.org)
  • Secondly, choline supplementation reduces the activation of microglia - cells responsible for clearing away debris in the brain. (azbio.org)
  • Choline supplementation reduces the activation of microglia, offering further protection from the ravages of Alzheimer's disease. (azbio.org)
  • This dissertation research sought to examine the effects of choline supplementation during pregnancy in the Dlx3+/- mouse, a model of placental insufficiency. (cornell.edu)
  • Study 1 investigated the effects of maternal choline supplementation (MCS) on pregnancy outcomes in Dlx3+/- mice. (cornell.edu)
  • This study demonstrated that maternal choline supplementation led to a marked increase in fetal growth by mid-gestation, which resulted in compensatory mechanisms to slow growth by downregulating Igf1. (cornell.edu)
Known as trimethylglycine3
  • Investigations into the cellular mechanics of hydration, waste removal and the postponement of fatigue have led researchers to betaine, also known as trimethylglycine, a nutrient that helps support cell hydration and volume during the dehydration, stress, and metabolite accumulation associated with high-intensity exercise. (prosource.net)
  • One supplement that has been gaining lots of attention lately is betaine (also known as trimethylglycine). (pumpsomeiron.com)
  • Extracted from the molasses of sugar beets, the natural betaine in BetaPower™ is also known as trimethylglycine. (fruit-processing.com)
Trimethylglycine2
  • Effect of supplementation with trimethylglycine (betaine) and/or vitamins on semen quality, fertility, antioxidant status, DNA repair and welfare of roosters exposed to chronic heat stress. (scielo.br)
  • Betaine (commonly referred to as trimethylglycine or TMG) is an amino acid that is commonly found in beets, which is where it first got its name. (pumpsomeiron.com)
Anhydrous3
  • Eighteen resistance trained men (23±5y) visited the laboratory after supplementing with either 6g/day betaine anhydrous (BET) or equivalently-dosed placebo (PLA) for 14-days. (wku.edu)
  • Danisco's betaine ingredient - BetaPower - is a natural betaine anhydrous grade. (nutraingredients-usa.com)
  • Betaine Anhydrous As a Pre-Workout Stimulant? (pumpsomeiron.com)
Placebo15
  • Prior to and following 14 days of twice daily B or placebo (P) supplementation, subjects completed two consecutive days (D1 and D2) of a standardized high intensity strength/power resistance exercise challenge (REC). (biomedcentral.com)
  • In the only study published to date on the effects of prolonged (14-15 days) betaine supplementation (1.25 g twice per day) on power performance, Hoffman and coworkers [ 6 ] reported no significant differences between betaine and placebo groups in the total repetitions performed to exhaustion at 75% 1RM, or in the number of repetitions performed at 90% of both peak and mean power, in the bench press exercise. (biomedcentral.com)
  • 0.05) on days 7-8 of betaine ingestion, and showed a similar trend (p = 0.06) on day 14-15, compared to the placebo group. (biomedcentral.com)
  • In a recent study published in the journal Amino Acids , study participants supplemented with placebo, creatine, or a combination of betaine and creatine over a period of 10 days. (prosource.net)
  • The creatine/betaine supplemented subjects experienced significant increases in power output during squat exercises when compared to the placebo group. (prosource.net)
  • The small-scale double-blind placebo-controlled trial found that the benefits of betaine supplementation were particularly apparent in the smaller upper-body muscle groups. (nutraingredients-usa.com)
  • The men all underwent a baseline two-day testing on physical performance, and were then randomly assigned to receive daily supplementation with betaine or placebo. (nutraingredients-usa.com)
  • Placebo was Gatorade without betaine. (nutraingredients-usa.com)
  • At the end of the 14 days, the betaine group displayed increased bench throw power and isometric bench press force compared to pre-supplementation and compared to the placebo group. (nutraingredients-usa.com)
  • The 24 subjects were split into two groups: one was given a daily placebo, and the other received betaine. (pumpsomeiron.com)
  • Subjects were then split into two groups: one receiving placebo and the other 2.5 grams of betaine daily. (pumpsomeiron.com)
  • Researchers found that the betaine group managed to do greater weekly training volumes when compared to placebo. (pumpsomeiron.com)
  • It revealed that subjects given an electrolyte drink containing Danisco's BetaPower™ Natural Betaine, performed better when cycling than those given a placebo. (fruit-processing.com)
  • Their cycling performance was measured against a benchmark performance that was recorded prior to a one-week betaine supplementation period and against an electrolyte drink placebo. (fruit-processing.com)
  • Betaine ingestion significantly increased average peak power, maximum peak power, average mean power and maximum mean power for all subjects combined compared to both placebo and baseline. (fruit-processing.com)
Determine if betaine2
  • This supplement can be great for you to try under supervision because the symptoms of low stomach acid often mirror those of high stomach acid, so it's important to be tested in order to determine if betaine HCl supplementation could be helpful for you. (consciousnutrition.com)
  • 9 ). In it, the team of researchers wanted to determine if betaine supplementation had any beneficial effects for athletic performance and body composition in women. (pumpsomeiron.com)
Benefits of betaine1
  • The results of this study add to the growing body of science supporting the benefits of betaine for athletic performance and as an important nutrient," adds Craig. (fruit-processing.com)
Evidence that betaine1
Hydrochloride3
  • Betaine hydrochloride is naturally found in beets and assists in the absorption of B12, calcium, iron and proteins. (consciousnutrition.com)
  • Betaine hydrochloride mirrors the action of healthy stomach acid levels increasing the comfort of digestion. (ovitaminpro.com)
  • This means taking three 500 mg capsules of a good blend of amino acids (ideally formulated to mimic the balance found naturally in an egg), together with one or two tablets of betaine hydrochloride, and three to six kelp tablets after each meal. (lesliekenton.com)
Repetitions performed2
  • For instance, in a published College of New Jersey study, athletes supplementing with this osmolytic agent experienced an increase of 30% in squat repetitions after 7 days of supplementation and 60% after 14 days, as well as significant increases in the quality of repetitions performed. (prosource.net)
  • Multi-nutrient supplementation improved vertical jump power, repetitions performed at 80% of their one-repetition maximum (1RM) and also favorably impacted hormonal changes [ 4 ]. (medsci.org)
Vitamin C supplementation1
  • This study investigated how combined betaine and vitamin C supplementation affect the productive performance of quails raised in a reduced floor space. (icsae.id)
Natural betaine2
  • BetaPower™ Natural Betaine, which is inherent in most living things, is found in particularly high levels in beets, wheat, spinach and shellfish. (fruit-processing.com)
  • BetaPower™ Natural Betaine is highly soluble and stable, so it can be used in a wide variety of product formulations developed for sports performance/enhancement, nutrition and hydration. (fruit-processing.com)
Show that supplementation1
  • Studies show that supplementation with 2.5 grams of betaine daily can help improve endurance, reduce muscular fatigue and support muscular strength. (priceplow.com)
Methionine5
  • Betaine is a significant determinant of plasma tHcy, particularly in case of folate deficiency, methionine load, or alcohol consumption. (nih.gov)
  • Betaine supplementation has a lowering effect on post-methionine load tHcy. (nih.gov)
  • Betaine has also been linked to healthy homocysteine levels and in the synthesis of precursors for SAM-e (S-adenosyl-L-Methionine). (ovitaminpro.com)
  • Effects of methionine and betaine supplementation on growth performance, carcass composition and metabolism. (tdtraktorist.ru)
  • And with the presence of S-adenosyl methionine (SAMe) during the process of methionine regeneration, Betaine has also been observed to treat depression/ anxiety, the first use of anabolic steroids was in the treatment for what ailment. (tdtraktorist.ru)
Homocysteine levels3
Ergogenic5
  • We investigated the ergogenic effects of betaine (B) supplementation on strength and power performance. (biomedcentral.com)
  • Considering the known importance of dietary betaine, the safety of betaine supplementation [ 2 ], and prevalence of betaine in foods typical of affluent American diets [ 9 ], this study aimed to further investigate the yet undefined ergogenic effects of betaine on resistance exercise, particularly on strength and power performance. (biomedcentral.com)
  • So far, we've seen mixed results from the research, with the majority of studies finding some ergogenic effects of betaine supplementation. (pumpsomeiron.com)
  • We've seen more and more pre-workout supplements containing betaine in recent years, as the amino acid seems to show ergogenic benefits. (pumpsomeiron.com)
  • Also, for people who engage in creatine supplementation, take BCAAs, nitrate, or others of these other ergogenic aids separately, a high-quality pre-workout can be quite an efficient one-stop-shop of a supplement. (garagegymreviews.com)
1.251
Hydrochloric acid2
  • Betaine HCl is hydrochloric acid that is naturally found in the gastric juices of the stomach. (elisreview.com)
  • Betaine HCl is a hydrochloric acid that helps break down foods, while pepsin is a proteolytic enzyme that aids in the digestion of proteins. (elisreview.com)
Creatine monohydrate1
  • While a near infinite combination of ingredients can exist, most multi-nutrient formulations contain a combination of key ingredients such as creatine monohydrate, amino acids, betaine, selected botanicals and plant extracts, carbohydrates, and caffeine [ 3 - 6 ]. (medsci.org)
Dietary2
  • Supplementation with various over-the-counter dietary supplements and "nutrient timing" are two popular approaches used by athletes to aid in performance and recovery [ 1 , 2 ]. (medsci.org)
  • Animal models have shown more directly that DNA methylation can be affected by dietary supplements that act as cofactors in one-carbon metabolism, and in humans, methylation at birth has been associated with peri-conceptional micronutrient supplementation. (frontiersin.org)
Grams1
  • A small human study from Serbia suggests that supplementation with 4 grams of creatine per day can speed up the healing process from Covid. (ergo-log.com)
Donor5
  • Folic acid supplementation spares betaine as a methyl donor. (nih.gov)
  • Our previous studies have shown that betaine, a methyl-donor, has efficacy in alleviating or preventing cardiac defects associated with CHDs in an avian model. (aap.org)
  • Choline is a precursor for several molecules with crucial roles during pregnancy: the methyl donor betaine, the neurotransmitter acetylcholine, and the phospholipid phosphatidylcholine. (cornell.edu)
  • TMG is a methyl donor that complements NMN supplementation by helping replenish the body's methyl pool. (prohealth.com)
  • As a compound, betaine has two primary functions within the body: as an osmolyte and as a methyl donor. (pumpsomeiron.com)
Methyl donors1
  • Protecting NCCs by supplementation with methyl donors and anti-oxidants may reduce the effects of PAE. (aap.org)
Metabolic4
  • This study examines whether supplementation of betaine, a choline derivative, has positive effects on fetal metabolic outcomes in mouse progeny exposed to maternal obesity and GDM. (cuny.edu)
  • Changes in plasma concentrations of total homocysteine (tHcy) reflect one aspect of the metabolic consequences of methyl group deficiency or nutrient supplementations. (nih.gov)
  • Our metabolomics discovery of metabolic pathway supplementations and/or rescue mechanisms may serve as adjunctive therapies for NE. (nature.com)
  • Through betaine, it participates in the metabolic network referred to as one-carbon metabolism which is essential for many biochemical processes including nucleotide synthesis, DNA methylation, and amino acid metabolism. (cornell.edu)
Fetal growth2
  • Maternal betaine supplementation affects fetal growth and lipid metabo" by Yaelle Joselit, Khatia Nanobashvili et al. (cuny.edu)
  • Placental betaine concentrations were strongly predictive of fetal weights, suggesting betaine supply may be a determinant of fetal growth. (cornell.edu)
Intake1
  • Prior to (d 1 to 34) and following heat exposure (d 35 to 41), betaine supplementation had no significant effect on body weight, total feed intake and cumulative feed conversion ratios of broilers. (upm.edu.my)
Curcumin1
  • If your liver is having a hard time - and there is more AST and ALT in your blood than you would like - curcumin supplementation may help you get the situation under control. (ergo-log.com)
Nutrient found2
  • Betaine is a nutrient found in foods such as shellfish, spinach, beets and whole grains. (nutraingredients-usa.com)
  • The research examined the effect of betaine, a nutrient found at high levels in spinach and whole grain, on cycling sprint performance 1 . (fruit-processing.com)
Efficacy2
  • Although the present findings do not support an extra-to-intracellular fluid flux-mediated BFR-betaine synergy, they further substantiate previous literature touting efficacy of either distinct modality. (wku.edu)
  • We hypothesized that betaine supplementation would be associated with improved strength and power in these individuals, thus demonstrating the potential efficacy of betaine in improving performance and recovery in strength and power exercise. (biomedcentral.com)
Positively1
  • In that study, researchers noted that twice-daily betaine supplementation positively impacted some of the athletic parameters. (pumpsomeiron.com)
Researchers3
  • Because of its increasing popularity, betaine has gotten the attention of many fitness enthusiasts and researchers alike. (pumpsomeiron.com)
  • Researchers found that betaine supplementation led to improved endurance on the squat and an increase in the quality of repetitions. (pumpsomeiron.com)
  • Beet root is very high in betaine of which the researchers were able to show that following supplementation with 1.2g betaine twice a day test subjects improved bench press force, throwing force, and vertical jump power. (tmrzoo.com)
Beta Alanine1
  • Click here now More about this company here A few of the very best pre-workouts include beta-alanine, citrulline, and also betaine. (tomsunic.info)
Study investigated1
  • This study investigated the effects of long term betaine supplementation on body composition, performance, and homocysteine thiolactone (HCTL) in experienced strength trained men. (nih.gov)
Metabolism2
Supplement7
  • In this prospective, randomized, double-blind, trial conducted in two parts, we examined the effects of a multi-ingredient pre-exercise workout supplement blend of creatine, betaine and a dendrobium extract (MMP) on safety, performance, and body composition in healthy men and women undergoing a supervised program of resistance exercise. (medsci.org)
  • In the current study, the primary effect of the betaine supplement was observed in the upper body, with enhanced bench press force and power production, but no change in the dynamic squat exercise performances. (nutraingredients-usa.com)
  • So if you are looking for a way to improve your health, consider taking a betaine supplement. (elisreview.com)
  • NOW Supplements Betaine HCl is a powerful supplement that can help improve your overall health. (elisreview.com)
  • With its wide range of health benefits, NOW Supplements Betaine HCl is an ideal supplement for those looking to improve their overall health and well-being. (elisreview.com)
  • If you're looking for a digestive enzyme supplement that can help you achieve optimal digestion and nutrient absorption, give Pure Encapsulations Betaine HCl Pepsin a try. (elisreview.com)
  • If you're looking for a digestive supplement that can help you break down food and absorb nutrients, Pure Encapsulations Betaine HCL Pepsin is a great option. (elisreview.com)
Endurance3
  • NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression. (prohealth.com)
  • Another study from the year before looked into the effects of 15 days of betaine supplementation on muscle endurance and time to exhaustion in college-aged men ( 8 ). (pumpsomeiron.com)
  • Research shows that supplementation with 800 mg of Siberian ginseng can improve VO2 max and endurance time! (priceplow.com)
Supplements on the market1
Pepsin3
  • If you're struggling with occasional indigestion, Pure Encapsulations Betaine HCl Pepsin may be just what you need. (elisreview.com)
  • Pure Encapsulations Betaine HCl Pepsin is also great for those who have trouble producing enough stomach acid on their own. (elisreview.com)
  • Integrative Therapeutics Betaine HCL w/pepsin then adds pepsin, an acid-stable protease, providing extra support for protein digestion. (ovitaminpro.com)
Liver5
  • The antioxidant betaine potentially helps prevent or reduce fatty deposits in the liver, according to animal studies . (healthline.com)
  • Betaine may also help protect your liver from toxins, though more studies are needed . (healthline.com)
  • Supplementation with a hefty dose of vitamin E improves liver health in non-alcoholic fatty liver disease. (ergo-log.com)
  • Beyond its sports nutrition benefits, betaine has also been linked to heart, liver and kidney health. (nutraingredients-usa.com)
  • Additionally, betaine HCl has been shown to promote healthy liver function and provide protection against oxidative stress. (elisreview.com)
Squat1
  • After the 14 days' supplementation, participants repeated the two-day exercise protocol, which included high-intensity strength/power resistance exercises such as bench throw, bench press, vertical jumps and squat repetitions. (nutraingredients-usa.com)
Digestion2
  • This unique formula provides 648 mg of betaine HCl per serving, which can help support healthy digestion and nutrient absorption. (elisreview.com)
  • Betaine HCl is designed to support healthy digestion by helping to maintain proper stomach acid levels. (elisreview.com)
Effects5
  • Overall, the data collected indicated that the meat quality of lambs (especially in the LD) improved as a result of betaine supplementation, and RPB showed better effects than those of UPB. (illinois.edu)
  • The effects of supplemental betaine (Betafin®) in the drinking water (50 g/kg) (WB) or feed (100 g/kg) (FB) were investigated on male broiler chickens (CobbxCobb) exposed to 4 h episodes of heat stress at 34±1°C on day (d) 35 and 36±1°C from d 36 to 41. (upm.edu.my)
  • The current study, funded by Danisco and published in the open access Journal of the International Society of Sports Nutrition ​, tested the effects of betaine supplementation on strength and power performance. (nutraingredients-usa.com)
  • Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. (prohealth.com)
  • The second study delved into the effects of betaine supplementation on strength and power performance 3 . (fruit-processing.com)
Outcomes1
  • Early evidence of positive outcomes of betaine supplementation collected from clinical studies has been encouraging. (prosource.net)
Amino1
  • Structurally, betaine is the amino acid glycine but with three methyl groups attached to it, which is where it gets its scientific name - trimethyl glycine. (pumpsomeiron.com)
Histidine3
  • Compared with CTL, the content of histidine in the LD increased with betaine supplementation. (illinois.edu)
  • In regression models, histidine and C6 sugar amine were significantly associated with cognitive, motor, and language and betaine with cognitive and motor Bayley-III composite scores. (nature.com)
  • The addition of histidine, C6 sugar amine, and betaine to a Sarnat score-based clinical regression model significantly improved model performance (Akaike information criterion and adjusted r 2 ) for Bayley-III cognitive, motor, and language scores. (nature.com)
Vitamins1
0.051
Body composition3
  • MPP supplementation for 6 weeks did not improve dual-energy x-ray absorptiometry (DEXA) measures of body composition or objective assessments of exercise performance. (medsci.org)
  • Over a six-week training and supplementation period, MPP use was not associated with improvements in performance or body composition. (medsci.org)
  • Six-weeks of betaine supplementation improved body composition, arm size, bench press work capacity, attenuated the rise in urinary HCTL, and tended to improve power (p = .07) but not strength. (nih.gov)
Absorption1
  • Rumen-protected betaine (RPB) can enhance betaine absorption in the small intestine of ruminants, while betaine can alter fat distribution and has the potential to affect the meat quality of livestock. (illinois.edu)
Nutrients1
Significantly greater1
  • Creatine/betaine supplementation led to significantly greater increases in maximal upper-body and lower-body strength as well. (prosource.net)
Concentrations1
Intracellular2
  • Blood flow restriction (BFR) training and betaine supplementation both possibly facilitate myofibril-level mechanotransduction via intracellular cell swelling. (wku.edu)
  • To explore a potential extra-to-intracellular fluid flux-mediated BFR-betaine synergistic effect on intramuscular phosphorylated signaling targets. (wku.edu)
Mice1
  • C57BL/6J mice were fed either a high-fat (HF) diet or a control (normal-fat, NF) diet and received either 1% betaine (BS) or control untreated (BC) drinking water 4-6 weeks before timed-mating and throughout gestation. (cuny.edu)
Effect1