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  • hemodialysis
  • Several studies have shown a reduction in many inflammation-related parameters, better nutritional indices, reduced beta-2-microglobulin levels, and improved anemia management achieved with less erythropoietin stimulating agents when hemodialysis patients are treated with ultrapure dialysate, in comparison with standard dialysate. (thefreedictionary.com)
  • cytochrome
  • In an article appearing in the December 2007 issue of the JASMS, researchers at Leeds describe the successful separation and analysis of various folded forms of the proteins cytochrome c and beta-2-microglobulin , an achievement the Ashcroft Laboratory hopes will lead to a more complete understanding of the biological processes responsible for amyloid fibril formation, bacterial pilus aggregation and virus capsid assembly -- all associated with debilitating diseases. (thefreedictionary.com)
  • proteins
  • The 90/45 kD LA45 proteins thus appear to be non-beta 2m-associated MHC class I alpha chains that are selectively expressed by activated but not by resting human T lymphocytes. (rupress.org)
  • Beta globulins are a group of globular proteins in plasma that are more mobile in alkaline or electrically charged solutions than gamma globulins, but less mobile than alpha globulins. (wikipedia.org)
  • amyloid
  • However, this mutation apparently precludes the formation of long amyloid fibrils and instead progress to off-pathway oligomers [2] . (proteopedia.org)
  • nephrotoxicity
  • Human Beta 2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumors and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy). (prospecbio.com)
  • removal
  • However, Nephros' Mid-Dilution HDF showed an 18% improvement in phosphate clearance over HD, as well as a statistically significant improvement in clearances and removal percentages for beta-2-Microglobulin ("b2M") and leptin. (thefreedictionary.com)
  • Barril concluded that Mid-Dilution HDF therapy is an effective alternative to standard HDF, enabling high convective transport (thereby more effectively removing larger toxins associated with malnutrition, infection, a range of other maladies and mortality in the ESRD patient), with (1) effective removal of Beta-2-microglobulin , (2) adequate balance of adipocytokines, relating to increases in appetite and (3) an overall improved distribution of fluids and body composition. (thefreedictionary.com)
  • Marker
  • 2. Drbal K, Angelisova P, Hilgert I, Cerny J, Novak P, Horejsi V.: A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells. (acris-antibodies.com)
  • Enzyme
  • Thymidine kinase is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase, EC 2.7.1.21 that catalyzes the reaction: Thd + ATP → TMP + ADP where Thd is (deoxy)thymidine, ATP is adenosine 5'-triphosphate, TMP is (deoxy)thymidine 5'-phosphate and ADP is adenosine 5'-diphosphate. (wikipedia.org)
  • Thymidine kinase 1 is such a salvage enzyme, whereas thymidine kinase 2 is not cell cycle-dependent. (wikipedia.org)