• Cite this: Teplizumab Preserves Beta Cells in New-Onset Type 1 Diabetes - Medscape - Oct 18, 2023. (medscape.com)
  • Beta has twice been used to name an Atlantic Basin tropical cyclone: Hurricane Beta, in 2005 Tropical Storm Beta, in 2020 Beta is often used to denote a variable in mathematics and physics, where it often has specific meanings for certain applications. (wikipedia.org)
  • Wayward Soundtrack: Volume Beta is the long awaited follow-up to the original 9 tracks, composed and produced by Austin Dhillon throughout 2018. (steampowered.com)
  • Google makes an interesting move yesterday jumping into the realm of academic and scholar web search by releasing the beta version of Google Scholar . (seroundtable.com)
  • Feedback from beta testers helps to enhance the product's performance, usability, and compatibility, ensuring it meets the needs and expectations of the target audience. (devx.com)
  • The feedback collected from the beta testers enables developers to improve the product's performance, usability, and overall experience, ensuring a higher quality and more stable release for the general public. (devx.com)
  • Consequently, beta testing serves as a fundamental, user-centric strategy that ensures technological products deliver on the promise of functionality, usability, and overall satisfaction, contributing to a more favorable reception upon its public release. (devx.com)
  • As with all of our Fedora releases, we aim to make life better for desktop users with several enhancements and upgrades for Fedora 22 Workstation Beta, from usability to the appearance and user interface (UI). (redhat.com)
  • The Fedora 13 Beta release gives an early peek at free and open source technologies that reach new heights of functionality and usability. (osnews.com)
  • A beta-screen forms when there is a deficiency in alpha-functioning and beta-elements replace the contact-barrier. (encyclopedia.com)
  • Beta thalassemia syndromes are a group of hereditary disorders characterized by a genetic deficiency in the synthesis of beta-globin chains. (medscape.com)
  • Detection and functional characterization of the novel missense mutation Y254D in type II 3 beta-hydroxysteroid dehydrogenase (3 beta HSD) gene of a female patient with nonsalt-losing 3 beta HSD deficiency. (medscape.com)
  • GNOME and Windows 8 developments have resulted in some controversial changes for Ubuntu 12.10 (codenamed Quantal Quetzal), which has now reached the Beta 2 stage. (zdnet.com)
  • Unfortunately, Nautilus 3.6 no longer provides the features felt to be essential to Ubuntu, and so - as already reported in our Beta 1 preview - Ubuntu 12.10 sticks with Nautilus 3.4. (zdnet.com)
  • The Quantal Quetzal Beta Release of Ubuntu GNOME Remix 12.10 is a developer snapshot to give you a very early glance at the next version of Ubuntu GNOME Remix. (ubuntu.com)
  • Android Q Beta gives you access to an early build of Android Q. Joining this program earns you a chance to experience Android Q ahead of its launch, test and share your feedback, or develop your apps to make it compatible with the official Android Q platform. (asus.com)
  • Please note that Android Q Beta is not the final build, so some features might be missing or not working properly. (asus.com)
  • To learn more about Android Q Beta, please visit Android Q Beta developer site . (asus.com)
  • The current Android Q Beta version does not support VoLTE or Gesture Navigation. (asus.com)
  • Android Q Beta updates are sometimes not as stable as official ASUS firmware updates. (asus.com)
  • Please note that this Android Q Beta version is stock Android. (asus.com)
  • Hi all, Today, we pushed a small number of GPL projects for Android 14 Beta 1. (google.com)
  • The tag is android-u-beta-1-gpl. (google.com)
  • Beta blockers, such as propranolol, oxprenolol, and sotalol, are used to treat disorders of the cardiovascular system , including high blood pressure (hypertension), angina pectoris , and irregularities of heartbeat (arrhythmias). (encyclopedia.com)
  • Beta-blockers are not suitable for patients with asthma or severe lung disease. (encyclopedia.com)
  • Beta can be calculated as the covariance of a financial asset (or portfolio) with its benchmark index, divided by the variance of the benchmark index. (wikipedia.org)
  • One measure for this is beta (known as "market risk"), based on the statistical property of covariance. (selfgrowth.com)
  • However, we show that modifications of the xylose moiety of the beta-D-xylopyranosides can render inhibitors of galactosylation. (lu.se)
  • In the International Phonetic Alphabet, Greek minuscule beta denotes a voiced bilabial fricative [β]. (wikipedia.org)
  • Variants (also known as mutations) in the HBB gene cause beta thalassemia. (medlineplus.gov)
  • The HBB gene provides instructions for making a protein called beta-globin. (medlineplus.gov)
  • Some variants in the HBB gene prevent the production of any beta-globin. (medlineplus.gov)
  • Other HBB gene variants allow some beta-globin to be produced but in reduced amounts. (medlineplus.gov)
  • In these cases, one copy of the altered gene in each cell is sufficient to cause the signs and symptoms of beta thalassemia. (medlineplus.gov)
  • Peripheral smear in beta-zero thalassemia minor showing microcytes (M), target cells (T), and poikilocytes.The genetic defect usually is a missense or nonsense mutation in the beta-globin gene, although occasional defects due to gene deletions of the beta-globin gene and surrounding regions also have been reported. (medscape.com)
  • [ 7 , 8 ] As background, in 2009, Collombat and colleagues [ 9 ] showed that pancreatic misexpression of the gene Pax4 led to the conversion of glucagon -producing alpha cells into functional beta cells. (medscape.com)
  • These mutations, by causing impaired synthesis of the beta-globin protein component of Hb, result in anemia. (medscape.com)
  • In beta thalassemia minor (ie, beta thalassemia trait or heterozygous carrier-type), one of the beta-globin genes is defective, resulting in an approximately 50% decrease in the synthesis of the beta-globin protein. (medscape.com)
  • All beta-lactams bind to and inactivate enzymes required for bacterial cell wall synthesis. (msdmanuals.com)
  • Since the industry of finance gravitates towards return generating activities, typically the historical returns (percentage changes) are used in the calculations Beta values (among others). (wikipedia.org)
  • Added a conteiner definition for the Minfo R package that should be used for the beta value calculations. (lu.se)
  • Teplizumab (Tzield) infusions in children and adolescents with new-onset type 1 diabetes met the primary endpoint of preserved beta-cell function and trended toward improved secondary glycemic endpoints. (medscape.com)
  • In type 1 diabetes , beta cells succumb to autoimmunity, leaving individuals with significantly reduced beta-cell mass and a lifelong dependence on insulin replacement therapy. (medscape.com)
  • Feature requests for the Beta release can also be submitted by opening a service request online. (vmware.com)
  • This is a BETA release, that should only be used on test sites. (joomla.org)
  • The feedback received from beta testers is crucial in refining the product for its eventual public release. (devx.com)
  • Beta testing is a critical phase in software development where the product is tested by a select group of users in real-world scenarios to identify and fix any bugs or issues before the final release. (devx.com)
  • The goal of our beta programs is to improve the release versions of Live 11 and Push software by finding and removing any unintended behavior in the beta versions. (ableton.com)
  • We usually take a couple of weeks to polish the beta version before promoting it to the stable release stage. (opera.com)
  • Apple has provided developers with the sixth beta build of visionOS to try out, as the release of the Apple Vision Pro slowly approaches. (appleinsider.com)
  • The Beta release of Fedora 13 (codename "Goddard") blasts off today , true to its namesake, scientist and liquid-fueled rocketry pioneer Robert Hutchings Goddard . (osnews.com)
  • The Beta milestone is when the Fedora Project encourages users, developers, and administrators of all types to download and try out the release early. (osnews.com)
  • While generally the Beta is reasonably stable, this is the time for users to exercise their favorite parts of the system and report any lingering bugs before the final release. (osnews.com)
  • The Fedora 13 beta is pretty stable and is looking to be a very solid release. (osnews.com)
  • Es liegt vorerst eine Beta-Version vor. (4homepages.de)
  • Beta version? (bullzip.com)
  • Opera beta is one step away from the final version, but still a work in progress. (opera.com)
  • In a continuing bid to capture some of the tape-backup market, Microsoft on Wednesday released a beta version of the upgrade to its file-and-application server recovery software, which includes support for a wider range of the company's server products. (cio.com)
  • A few days ago, Apple surprised everyone by releasing the first beta of Safari 4 , the company's latest version of their WebKit browser. (osnews.com)
  • Beta thalassemia affects one or both of the beta-globin genes. (medscape.com)
  • This team showed that injection of just three genes- Neurog3, Mafa, and Pdx1 -into the pancreatic parenchyma of mice leads to conversion of exocrine cells to functional beta cells, a process popularly known as "reprogramming. (medscape.com)
  • Studies of 3 beta-hydroxysteroid dehydrogenase genes in infants and children manifesting premature pubarche and increased adrenocorticotropin-stimulated delta 5-steroid levels. (medscape.com)
  • For example, typing in 'Fir' ( en route to 'Firefox') also generates hits for a Kindle Fire and, among other odd results, various music download links via the Ubuntu One cloud service. (zdnet.com)
  • Beta-lactams are antibiotics that have a beta-lactam ring nucleus. (msdmanuals.com)
  • Objective: The indiscriminate use of antibiotics has led to the creation of resistant microorganisms, with the aim of this study was to compare in vitro the degree of effectiveness of beta-lactam antibiotics and glycopeptide in the inhibition of Staphylococcus aureus by comparing its effectiveness in surgical wound infection. (bvsalud.org)
  • Peripheral smear in beta-zero thalassemia minor showing microcytes (M), target cells (T), and poikilocytes. (medscape.com)
  • The introduction of fluorescent proteins that can be targeted to the secretory granules, in combination with the advent of new techniques that allow real-time imaging of granule trafficking in living cells (granule dynamics), has led to an explosion of our knowledge of the pre-exocytotic and post-exocytotic processes in the beta cell. (lu.se)
  • In this study production levels of interleukins (IL)-12 and IL-13 were measured by commercial ELISA in culture supernatants of mitogen-stimulated peripheral blood mononuclear cells from 30 non-splenectomized beta-thalassaemia cases with iron overload and 20 age- and sex-matched healthy individuals. (who.int)
  • In recent years, we have come to appreciate that loss or dysfunction of insulin-producing islet beta cells underlies virtually all major forms of diabetes mellitus. (medscape.com)
  • In type 2 diabetes , beta cells fail to secrete sufficient insulin to overcome the prevailing insulin resistance . (medscape.com)
  • Although a few FDA-approved therapies for type 2 diabetes (meglitinides, sulfonylureas, incretin-based drugs) directly enhance beta-cell function, no therapies for any form of diabetes lead to the growth of healthy, new beta cells to replace those that were lost or dysfunctional. (medscape.com)
  • Multiple strategies to replace beta cells in individuals with diabetes have been considered. (medscape.com)
  • A more appealing strategy involves the transplantation of beta cells grown from stem cells, particularly with recent advances in generating large numbers of beta cells from human stem cells. (medscape.com)
  • Still missing from these approaches is any attempt to induce regeneration or replication of endogenous beta cells in the pancreas, an approach that would be physiologically desirable. (medscape.com)
  • A 2008 study by Zhou and colleagues [ 6 ] provided early insight into how endogenous cells in the pancreas could be coaxed into becoming beta cells. (medscape.com)
  • Using careful, state-of-the-art cell tracking techniques, the same group subsequently showed that Pax4 misexpression initially caused the conversion of cells lining the ducts to become alpha cells, which were then converting to beta cells. (medscape.com)
  • The term 'Beta Motorcycles Australia' or 'us' or 'we' refers to the owner of the website whose registered office is 1/19 Expansion St, MOLENDINAR, QLD, 4214, AU. (betamotor.com.au)
  • The uppercase letter beta is not generally used as a symbol because it tends to be rendered identically to the uppercase Latin B. The term "beta" refers to advice on how to successfully complete a particular climbing route, boulder problem, or crux sequence. (wikipedia.org)
  • Beta test refers to the phase of software development where a product, in its nearly completed state, is released to a limited group of users for testing. (devx.com)
  • Two of the biggest changes in Quantal Quetzal, already introduced in Beta 1, are the addition of the Unity Dash preview feature and the removal of the Unity 2D shell to simplify Unity development. (zdnet.com)
  • Sensitivity of S. aureus to beta-lactam and glycopeptide. (bvsalud.org)
  • If you feel like being an innovator, we invite you to try our newest browser features and experiments in our Opera beta and Opera developer releases. (opera.com)
  • You can read about the latest additions to Opera Browser beta and Opera Browser developer on our Desktop team's blog . (opera.com)
  • Each of the browsers is a separate installations, so you can use the different versions in parallel: developer, beta and stable. (opera.com)
  • This vital phase in the developmental life cycle comes after alpha testing and entails a more specific group of users, typically known as beta testers, who thoroughly examine the product under real-world scenarios. (devx.com)
  • This highly collaborative approach benefits not only developers but also the end-users, as beta testers often comprise both experts in the relevant field and a sample of the target audience. (devx.com)
  • Many of the suggestions made by beta testers were implemented in the final product. (devx.com)
  • Hemoglobin consists of four protein subunits, typically two subunits of beta-globin and two subunits of another protein called alpha-globin. (medlineplus.gov)
  • During the beta testing phase, users provided valuable feedback on the design, functionality, and user experience of the product. (devx.com)
  • Beta-alanine and carnosine together help improve the muscles' functionality due to various body processes during exercise. (medicalnewstoday.com)
  • Fass environmental information for Puregon (follitropin beta) from MSD (downloaded 2019-05-08). (janusinfo.se)
  • beta blocker ( beta-adrenoceptor antagonist ) Any of a group of drugs that bind preferentially to beta adrenoceptors and hence block their stimulation by the body's own neurotransmitters, adrenaline and noradrenaline. (encyclopedia.com)
  • This means people following a vegan or vegetarian diet will likely have significantly less beta-alanine and carnosine in their system and require supplementation to enhance athletic performance. (medicalnewstoday.com)
  • As the beta-screen is composed of beta-elements which lend themselves to projective identification, it also manifests itself in a bombardment directed both against the alpha-functioning of the patient himself and against any external object susceptible to arousing meaningful feelings. (encyclopedia.com)
  • Beta male, or simply beta, is a slang term for men derived from the designation for beta animals in ethology, along with its counterpart, alpha male. (wikipedia.org)
  • Drawing a line of best fit through the data points allows us to quantify the passive risk (beta) and the active risk (alpha). (selfgrowth.com)
  • In our diagram example above, alpha is the amount of portfolio return not explained by beta, represented as the distance between the intersection of the x and y-axes and the y-axis intercept, which can be positive or negative. (selfgrowth.com)
  • The difference in pricing between passive and active strategies (or beta risk and alpha risk respectively) encourages many investors to try and separate these risks (e.g. to pay lower fees for the beta risk assumed and concentrate their more expensive exposures to specifically defined alpha opportunities). (selfgrowth.com)
  • This is popularly known as portable alpha, the idea that the alpha component of a total return is separate from the beta component. (selfgrowth.com)
  • Portable alpha strategies use derivatives and other tools to refine how they obtain and pay for the alpha and beta components of their exposure. (selfgrowth.com)
  • It all started when a group of brave women created a petition for Omega Phi Alpha to be welcomed into the national Pi Beta Phi sorority sisterhood. (uidaho.edu)
  • Dig out your pin, smile for the camera man and join your sisters at our beloved Idaho Alpha Pi Beta Phi! (uidaho.edu)
  • If you'd like to become a beta tester for the latest Push software, head to the Push beta testing portal . (ableton.com)
  • In any case, this latest beta has made a very bold move in the interface department, and I'm sad to say that it's not for the better. (osnews.com)
  • Before officially releasing a major iOS update, Apple releases beta versions to registered developers and the public, allowing them to test new features and provide feedback on any bugs or issues they encounter. (devx.com)
  • VMware offers self-help and web-based support for Beta users during the term of the Beta period. (vmware.com)
  • Beta tests can be either open (public), where anyone can participate, or closed (private), where only a specific group of users is invited to test the product. (devx.com)
  • The term "Beta Test" is essential in the technology industry as it represents a critical stage in the software development cycle where a product, either a software application or a hardware device, undergoes thorough testing by a select group of users before its official launch. (devx.com)
  • Gmail remained in its "beta" phase until 2009, even though it had millions of users by that time. (devx.com)
  • Though AppleInsider normally warns users not to install beta operating systems or software onto primary or "mission critical" hardware due to the possibility of data loss, the lack of hardware means it isn't a factor for the vast majority of beta participants. (appleinsider.com)
  • 2.1 Although utilizable by experienced users, AVG Beta Software is still being developed, tested and evaluated. (avg.com)
  • Conditional on the benchmark index, the resulting beta value can vary considerably (S&P500 vs NASDAQ vs ETF of a specific industry). (wikipedia.org)
  • beta-blocker Any of a class of drugs that block impulses to beta nerve receptors in various tissues throughout the body, including the heart, airways, and peripheral arteries. (encyclopedia.com)
  • In the heterozygous state, the beta thalassemia trait (ie, thalassemia minor) causes mild to moderate microcytic anemia. (medscape.com)
  • beta) results in ineffective erythropoiesis and severe microcytic hypochromic anemia. (medscape.com)
  • Based on enzymatic studies, that is galactosylation and its inhibition, conformational analysis and molecular modeling using the crystal structure, we propose that the binding pocket of beta 4GalT7 is very narrow, with a precise set of important hydrogen bonds. (lu.se)
  • A shortage of beta-globin hinders the formation of functional hemoglobin. (medlineplus.gov)
  • Beta testing serves a significant purpose within the domain of technology development by allowing developers to identify and eliminate any discrepancies or shortcomings in their products, such as software or hardware, before releasing them to the general public. (devx.com)
  • Moreover, beta testing can lead to the identification of novel product applications or use-cases, which could influence the evolution and improvement of the software or hardware. (devx.com)
  • This is BETA software! (neowin.net)
  • 1.1 Your use of the AVG Beta Software is governed by these terms and conditions ("Beta User Conditions") which you should read carefully before installing AVG Beta Software. (avg.com)
  • 1.3 These Beta User Conditions apply to you regardless of how you have accessed the AVG Beta Software and regardless of the territory in which you live or conduct business. (avg.com)
  • AVG Beta Software has not been released for sale, distribution or any use by the general public. (avg.com)
  • AVG Technologies will not provide any technical support, maintenance or any other services for any AVG Beta Software. (avg.com)
  • However, should AVG Technologies in its sole discretion provide you with any Updates, such Updates will be deemed to form part of AVG Beta Software for all purposes under these Beta User Conditions, unless other terms of use are provided by AVG Technologies in connection with such Updates. (avg.com)
  • Thank you for participating in the PS5 system software beta program. (playstation.com)
  • All editions of Fedora 22 Beta include an updated package manager for RPM-based Linux distributions called "DNF. (redhat.com)
  • The biosynthesis of GAG chains is initiated by xylosylation of a serine residue of the core protein, followed by galactosylation by beta 4GalT7. (lu.se)
  • In physics a stream of unbound energetic electrons is commonly referred to as beta radiation or beta rays. (wikipedia.org)
  • In spaceflight, beta angle describes the angle between the orbit plane of a spacecraft or other body and the vector from the sun. β is sometimes used to mean the proton-to-electron mass ratio. (wikipedia.org)
  • Over at the official Hellgate: London home page, you'll find a rather fetching link that'll let you sign up for the game's upcoming beta. (kotaku.com.au)
  • Added thumbnails of the beta adjustment plot to the derived bioassay list and view page for Methylation items. (lu.se)
  • citation needed] In the system of Greek numerals, beta has a value of 2. (wikipedia.org)
  • Apple iOS Public Beta: Apple often holds public beta tests for its iOS operating system updates. (devx.com)
  • All Beta versions are precursors of final products. (eset.com)
  • Because we don't expect Beta releases to be implemented in a production environment, and due to the volume of requests received, we cannot commit a response to each and every Beta service request. (vmware.com)
  • Dans la présente étude, les taux de production des interleukines 12 et 13 (IL-12 et IL-13) ont été mesurés à l'aide de la méthode ELISA dans les surnageants de culture de cellules mononucléées de sang périphérique stimulées par des mitogènes chez 30 cas de bêta-thalassémie non splénectomisés présentant une surcharge martiale ainsi que chez 20 individus en bonne santé appariés pour l'âge et le sexe. (who.int)
  • Beta-lactamase production is among the most clinically important mechanisms of resistance for gram-negative bacterial pathogens. (msdmanuals.com)
  • Customers with proper Beta Support Entitlement will be able to submit service requests online. (vmware.com)