• In this study, we have identified novel Triazole linked 2-phenyl benzoxazole derivatives (13j and 13h) as a negative regulator of apoptosis inhibiting micro RNAs ( miR-2, miR-13 and miR-14 ) in a well established in vivo model Drosophila melanogaster where the process of apoptosis is very similar to human apoptosis. (springer.com)
  • These twelve ligands were divided into two groups (A and B), with the first group consisting of derivatives of 2-(2'-hydroxphenyl)-benzoxazole and the second group consisting of three derivatives of 2-(4'-amino-2'-hydroxyphenyl)-benzazoles, alternating between N, S and O in the azole ring and three Tröger bases derived from them. (ufrgs.br)
  • 19. A compound according to claim 1 of the formula: 5-chloro-2-(3,5-di-t-butyl-4-hydroxy-benzyl)-7-(2-(2-pyridyl)-ethynyl)-benzoxazole. (google.com)
  • Benzoxazole, the compound that slowed bone aging by up to 31% over the course of a year's treatment in the mice, was first identified as one of five compounds that extended nematode lifespan in the Lithgow lab in a study that appeared in Nature in 2011. (nutritionreview.org)
  • Gandhi, A.M. / New benzoxazoles as potential antitumor agents . (elsevier.com)
  • It was also found that benzoxazoles and benzothiazoles exhibit significant herbicidal [ 16 - 25 ] and antialgal activity [ 18 , 19 , 26 , 27 ]. (hindawi.com)
  • Although the mode of action of some herbicidal benzoxazoles and benzothiazoles consists in inhibition of fatty acid synthesis, over 50% of commercially available herbicides act by reversible binding to photosystem II (PS II), a membrane-protein complex in the thylakoid membranes, which catalyses the oxidation of water and the reduction of plastoquinone [ 32 ], and thereby inhibit photosynthesis [ 33 - 35 ]. (hindawi.com)
  • Benzoxazole and its isosteres benzimidazole and benzothiazole represent privileged structures, that is, they are useful ligands for more than one type of receptor or enzyme targets by judicious structural modifications. (hindawi.com)
  • Isoquinoline, acridine, benzimidazole, and benzoxazole residues were introduced into the pyrazolone ring by reaction of N-heteroaromatic compounds with pyrazolones in the presence of acylating agents. (springer.com)
  • Benzoxazole is an aromatic organic compound with a molecular formula C7H5NO, a benzene-fused oxazole ring structure, and an odor similar to pyridine. (wikipedia.org)
  • Two series of aromatic poly(amide-benzoxazole)s have been obtained from 5-chlorocarbonyl-2-(4-chlorocarbonylphenyl)benzoxazole (NBOC) and 6-chlorocarbonyl-2-(4-chlorocarbonylphenyl)benzoxazole (OBOC). (csic.es)
  • The invention relates to bichromophoric benzotriazole-benzoxazole compounds which have been found to be effective ultraviolet stabilizers. (google.es)
  • The PET-inhibiting activity of the most active ortho -substituted compound 2-[( E )-2-(2-methoxyphenyl)ethenyl]-1,3-benzoxazole was IC 50 = 76.3 μ mol/L, while the PET-inhibiting activity of para -substituted compounds was significantly lower. (hindawi.com)
  • Las moléculas seleccionadas 6b y 6i se sometieron a acoplamiento molecular y luego a ensayo de afinidad basado en SPR. (isciii.es)
  • The benzoxazole system is present in numerous antimicrobial agents [ 5 , 7 - 15 ]. (hindawi.com)
  • Design of new benzoxazole-2-thione derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole. (uni-regensburg.de)
  • These benzoxazole-2-thiones constitute a new class of inhibitors of bacterial Hyals and are well suited for further optimization of their selectivity, potency, and pharmacokinetic properties. (uni-regensburg.de)
  • Ten new 2-(3-aryl-1-phenyl-4-pyrazolyl)benzoxazoles have been synthesized by oxidative intramolecular cyclization of the corresponding Schiff's bases using iodobenzene diacetate in methanol as an oxidant. (mdpi.com)
  • Prakash O, Pannu K, Kumar A. Synthesis of Some New 2-(3-Aryl-1-phenyl-4-pyrazolyl)-benzoxazoles Using Hypervalent Iodine Mediated Oxidative Cyclization of Schiff's Bases. (mdpi.com)
  • The crystal structure of 4-methyl-2-phenyl-7-isopropyl-1,3-benzoxazole-5-ol (1a) has been determined by X-ray diffraction. (ac.rs)
  • Cross-photodimerization of 4-(2-phenylethenyl)pyridine, 2-(2-phenylethenyl)benzoxazole and 5-phenyl-2-(2-phenyl-ethenyl) oxazole[J].Acta Phys. (pku.edu.cn)
  • Benzoxazoles belong to the group of well-known antifungal agents with antioxidant, antiallergic, antitumoral and antiparasitic activity. (wikipedia.org)
  • TQ and ATQ showed better antibacterial activity against tested Gram-positive and Gram-negative bacterial strains than benzoxazoles. (ac.rs)
  • Benzoxazole Derivative K313 Induces Cell Cycle Arrest, Apoptosis and Autophagy Blockage and Suppresses mTOR/p70S6K Pathway in Nalm-6 and Daudi Cells. (nih.gov)
  • Gandhi, A.M. / New benzoxazoles as potential antitumor agents . (elsevier.com)
  • The least toxic compound against normal fibroblast cells, which maintains similar antitumor activities as TQ, was 2-(4-chlorophenyl)-4-methyl-7-isopropyl-1,3-benzoxazole-5-ol (1e). (ac.rs)
  • Nataxazole, a New Benzoxazole Derivative with Antitumor Activity Produced by Streptomyces sp. (nature.com)
  • 1. Polymers derived from 2-(4-carboxyphenyl) benzoxazole-5- and 6-carboxylic acids. (csic.es)
  • It consists of the activation of enals with a secondary amine catalyst and the activation of benzoxazoles with a metal Lewis acid. (rsc.org)
  • Zirconium Dodecylphosphonate: Selective and Constructive Catalyst for Preparation of 2-Alkyl Benzoxazoles from Aliphatic Carboxylic Acids', Iranian Journal of Chemistry and Chemical Engineering (IJCCE) , 36(1), pp. 27-33. (ac.ir)
  • 2,2-(Thiophene-2,5-diyl)bis[5-(1,1-dimethylethyl)]-benzoxazole (CAS 7128-65-5) Market Research Report 2018 contents were prepared and placed on the website in February, 2018. (marketpublishers.com)
  • Please note that 2,2-(Thiophene-2,5-diyl)bis[5-(1,1-dimethylethyl)]-benzoxazole (CAS 7128-65-5) Market Research Report 2018 is a half ready publication and contents are subject to change. (marketpublishers.com)
  • The reaction of alkyl-benzoxazoles with enals has been reported using a synergistic approach. (rsc.org)
  • We demonstrated the applicability of this reaction in a cascade reaction (cyclopropanation + ring opening) that circumvents some of the limitations of the simple Michael addition between alkyl-benzoxazoles and enals. (rsc.org)
  • More particularly, the invention relates to bichromophoric benzotriazole-benzoxazole compositions and the stabilization of ultraviolet degradable organic compositions against deterioration resulting from the exposure to such radiations with such bichromophoric compositions. (google.es)
  • The glass transition temperatures were above 300°C, whilst the onset of thermal degradation ranged from 455 to 515°C. A theoretical study was also done, by means of computational chemistry methods, to relate the orientation of the benzoxazole ring in both series with monomer reactivity and polymer properties. (csic.es)
  • Keto-enol tautomerization of 2-(2'-hydroxyphenyl)benzoxazole and 2-(2'-hydroxy-4'-methylphenyl)benzoxazole in the triplet state: hydrogen tunneling and isotope effects. (mpg.de)
  • Intramolecular proton transfer and tunnel effects in the metastable triplet states of 2-(2′-hydroxyphenyl)benzoxazole studied by micro- and nanosecond laser flash photolysis. (mpg.de)
  • In the third chapter, Saini and Bhalla have described a benzoxazole scaffold for effective drug design in therapeutic drug design. (novapublishers.com)
  • CEPA) (Canada 1999), the Minister of the Environment and the Minister of Health have conducted a screening assessment of benzoxazole, 2,2'-(1,4-naphthalenediyl)bis-, hereinafter referred to as fluorescent brightener 367, to determine whether this substance presents or may present a risk to the environment or to human health. (canada.ca)
  • The structural data suggested a similar binding mode for N-(3-phenylpropionyl)-benzoxazole-2-thione. (uni-regensburg.de)
  • So, this method introduces a selective and constructive method for synthesis of 2-alkyl benzoxazoles without salt formation. (ac.ir)
  • Photoisomerization of 2-(2'-hydroxyphenyl) benzoxazole formation and decay of the trans-keto tautomer in dry and in water containing 3-methylpentane. (mpg.de)
  • Furthermore, 2,2-(thiophene-2,5-diyl)bis[5-(1,1-dimethylethyl)]-benzoxazole prices in regional markets can be found in the report with regards to countries and companies. (marketpublishers.com)